ES2056431T3 - Procedimiento para la produccion de r(+)-aminocarnitina y s(-)-aminocarnitina. - Google Patents

Procedimiento para la produccion de r(+)-aminocarnitina y s(-)-aminocarnitina.

Info

Publication number
ES2056431T3
ES2056431T3 ES90830159T ES90830159T ES2056431T3 ES 2056431 T3 ES2056431 T3 ES 2056431T3 ES 90830159 T ES90830159 T ES 90830159T ES 90830159 T ES90830159 T ES 90830159T ES 2056431 T3 ES2056431 T3 ES 2056431T3
Authority
ES
Spain
Prior art keywords
production
carnitine
amino
amino carnitine
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90830159T
Other languages
English (en)
Inventor
Maria Ornella Tinti
Domenico Misiti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2056431T3 publication Critical patent/ES2056431T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Catalysts (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCESO PARA LA PRODUCCION DE R(+)-AMINOCARNITINA Y S(-)-AMINO-CARNITINA MEDIANTE LA RESOLUCION DE LA COMBINACION DE LOS DIASTEREOISOMEROS DE CLORURO DE ESTER DE BENCILO DE N-(ALFA-METILBENZIL) AMINOCARNITINA, EN DONDE LOS DIASTEREOISOMEROS SEPARADOS SE DESBENCILAN POSTERIORMENTE PARA OBTENER EL CLORURO DE R(+)-AMINOCARNITINA Y DE S(-)-AMINOCARNITINA.
ES90830159T 1989-04-12 1990-04-11 Procedimiento para la produccion de r(+)-aminocarnitina y s(-)-aminocarnitina. Expired - Lifetime ES2056431T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8947842A IT1231751B (it) 1989-04-12 1989-04-12 Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina

Publications (1)

Publication Number Publication Date
ES2056431T3 true ES2056431T3 (es) 1994-10-01

Family

ID=11262871

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90830159T Expired - Lifetime ES2056431T3 (es) 1989-04-12 1990-04-11 Procedimiento para la produccion de r(+)-aminocarnitina y s(-)-aminocarnitina.

Country Status (9)

Country Link
US (1) US5041643A (es)
EP (1) EP0402322B1 (es)
JP (1) JP2941350B2 (es)
AT (1) ATE108174T1 (es)
DE (1) DE69010405T2 (es)
DK (1) DK0402322T3 (es)
ES (1) ES2056431T3 (es)
HK (1) HK1005866A1 (es)
IT (1) IT1231751B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238344B (it) * 1989-10-20 1993-07-13 Sigma Tau Ind Farmaceuti Estere della l-carnitina con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che lo contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma
IT1240760B (it) * 1990-02-12 1993-12-17 Sigma Tau Ind Farmaceuti Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma.
IT1254136B (it) * 1992-01-16 1995-09-08 Sigma Tau Ind Farmaceuti Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.
IT1254135B (it) * 1992-01-16 1995-09-08 Sigma Tau Ind Farmaceuti Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.
FR2688499B1 (fr) * 1992-03-10 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de la beta-phenylisoserine et de ses analogues.
US5939561A (en) * 1992-03-10 1999-08-17 Rhone-Poulence Rorer S.A. Process for the preparation of β-phenylisoserine and β-lactam and their analogues
HUT65327A (en) * 1992-06-11 1994-05-02 Sandoz Ag Process for producing phosphinyloxy-propyl-ammonium inner sact derwatives ang pharmateutical preparations containing them
IT1261230B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
IT1261828B (it) * 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
IT1261489B (it) * 1993-07-29 1996-05-23 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
US7776915B2 (en) * 2005-03-24 2010-08-17 Tracie Martyn International, Llc Topical formulations and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767781A (en) * 1981-11-26 1988-08-30 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate and their production and use
US4521432A (en) * 1981-11-26 1985-06-04 Takeda Chemical Industries, Ltd. Physiologically active substance FA-5859, its derivative, their production and use
CH652270GA3 (es) * 1983-05-19 1985-11-15
US4781863A (en) * 1984-04-02 1988-11-01 Cornell Research Foundation, Inc. Aminocarnitines
IT1205758B (it) * 1987-03-18 1989-03-31 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (-) n-acetil ammino carnitina e di (+) n-acetil ammino carnitina

Also Published As

Publication number Publication date
DE69010405D1 (de) 1994-08-11
JP2941350B2 (ja) 1999-08-25
EP0402322B1 (en) 1994-07-06
DK0402322T3 (da) 1994-10-24
IT8947842A0 (it) 1989-04-12
HK1005866A1 (en) 1999-01-29
JPH02304049A (ja) 1990-12-17
EP0402322A3 (en) 1991-01-02
DE69010405T2 (de) 1994-10-20
IT1231751B (it) 1991-12-21
EP0402322A2 (en) 1990-12-12
US5041643A (en) 1991-08-20
ATE108174T1 (de) 1994-07-15

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