ES2055529T3 - Nuevos derivados de piridina y procedimientos para su sintesis. - Google Patents
Nuevos derivados de piridina y procedimientos para su sintesis.Info
- Publication number
- ES2055529T3 ES2055529T3 ES91301571T ES91301571T ES2055529T3 ES 2055529 T3 ES2055529 T3 ES 2055529T3 ES 91301571 T ES91301571 T ES 91301571T ES 91301571 T ES91301571 T ES 91301571T ES 2055529 T3 ES2055529 T3 ES 2055529T3
- Authority
- ES
- Spain
- Prior art keywords
- procedures
- synthesis
- new
- piridine derivatives
- piridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 229940090865 aldose reductase inhibitors used in diabetes Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
Abstract
ESTA INVENCION SE REFIERE A UN PROCESO E INTERMEDIARIOS PARA LA PREPARACION DE AZOLONES-HETERO-SPIRO. LOS ULTIMOS COMPUESTOS SON UTILES COMO INHIBIDORES DE REDUCTASA ALDOSA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/490,906 US5068333A (en) | 1990-03-07 | 1990-03-07 | 6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2055529T3 true ES2055529T3 (es) | 1994-08-16 |
Family
ID=23949994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91301571T Expired - Lifetime ES2055529T3 (es) | 1990-03-07 | 1991-02-27 | Nuevos derivados de piridina y procedimientos para su sintesis. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5068333A (es) |
EP (1) | EP0445950B1 (es) |
JP (1) | JPH0586031A (es) |
AT (1) | ATE106871T1 (es) |
CA (1) | CA2037590A1 (es) |
DE (1) | DE69102315T2 (es) |
ES (1) | ES2055529T3 (es) |
FI (1) | FI911124A (es) |
IE (1) | IE910740A1 (es) |
PT (1) | PT96948A (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11257361A (ja) | 1998-01-08 | 1999-09-21 | Nippon Seiko Kk | 転がり軸受の密封装置 |
CN103664765A (zh) * | 2013-12-06 | 2014-03-26 | 常熟市联创化学有限公司 | 一种2-氨基-3-溴吡啶的制备方法 |
CN105061300B (zh) * | 2015-08-31 | 2018-02-16 | 南京红太阳生物化学有限责任公司 | 一种氯代吡啶及其衍生物的合成方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4176185A (en) * | 1979-01-22 | 1979-11-27 | Pfizer Inc. | Spiro-quinolylhydantoins |
FR2455046A1 (fr) * | 1979-04-25 | 1980-11-21 | Science Union & Cie | Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament |
US4287347A (en) * | 1980-05-12 | 1981-09-01 | Ciba-Geigy Corporation | Process for producing 2,3,5-trichloropyridine |
US4510148A (en) * | 1982-06-12 | 1985-04-09 | Pfizer Inc. | 2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents |
CA1217774A (en) * | 1983-09-06 | 1987-02-10 | Richard L. Burson | Halopyridines |
MX12896A (es) * | 1987-09-04 | 1993-06-01 | Pfizer | Procedimiento para preparar un compuesto de espiro-heteroazolonas |
US4980357A (en) * | 1990-03-01 | 1990-12-25 | Pfizer Inc. | Azolidinedione derivatives |
-
1990
- 1990-03-07 US US07/490,906 patent/US5068333A/en not_active Expired - Fee Related
-
1991
- 1991-02-27 ES ES91301571T patent/ES2055529T3/es not_active Expired - Lifetime
- 1991-02-27 AT AT91301571T patent/ATE106871T1/de not_active IP Right Cessation
- 1991-02-27 DE DE69102315T patent/DE69102315T2/de not_active Expired - Fee Related
- 1991-02-27 EP EP91301571A patent/EP0445950B1/en not_active Expired - Lifetime
- 1991-03-05 CA CA002037590A patent/CA2037590A1/en not_active Abandoned
- 1991-03-06 IE IE074091A patent/IE910740A1/en unknown
- 1991-03-06 FI FI911124A patent/FI911124A/fi not_active Application Discontinuation
- 1991-03-06 PT PT96948A patent/PT96948A/pt not_active Application Discontinuation
- 1991-03-07 JP JP3041860A patent/JPH0586031A/ja active Pending
-
1992
- 1992-10-14 US US07/961,049 patent/US5336771A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5068333A (en) | 1991-11-26 |
US5336771A (en) | 1994-08-09 |
ATE106871T1 (de) | 1994-06-15 |
JPH0586031A (ja) | 1993-04-06 |
IE910740A1 (en) | 1991-09-11 |
EP0445950B1 (en) | 1994-06-08 |
FI911124A0 (fi) | 1991-03-06 |
EP0445950A1 (en) | 1991-09-11 |
DE69102315T2 (de) | 1994-09-15 |
CA2037590A1 (en) | 1991-09-08 |
PT96948A (pt) | 1991-10-31 |
FI911124A (fi) | 1991-09-08 |
DE69102315D1 (de) | 1994-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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