ES2055454T3 - Compuestos de imidazoquinoxalina, su preparacion y uso. - Google Patents

Compuestos de imidazoquinoxalina, su preparacion y uso.

Info

Publication number
ES2055454T3
ES2055454T3 ES90917143T ES90917143T ES2055454T3 ES 2055454 T3 ES2055454 T3 ES 2055454T3 ES 90917143 T ES90917143 T ES 90917143T ES 90917143 T ES90917143 T ES 90917143T ES 2055454 T3 ES2055454 T3 ES 2055454T3
Authority
ES
Spain
Prior art keywords
branched
alkyl
hydrogen
straight
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90917143T
Other languages
English (en)
Inventor
Frank Watjen
Holger Claus Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2055454T3 publication Critical patent/ES2055454T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

NUEVOS COMPUESTOS DE IMIDAZOQUINOXALINA CON LA FORMULA (I) GENERAL, EN LA QUE Q ES (A) , EN LA QUE R1 Y R2 INDEPENDIENTEMENTE SON HIDROGENO, C1-6-ALQUILO DE CADENA RECTA O RAMIFICADA, O C3-7-CICLOALQUILO; R3 ES HIDROGENO, C1-6-ALQUILO DE CADENA RECTA O RAMIFICADA, C2-6-ALQUENILO DE CADENA RECTA O RAMIFICADA O ALQUILARILO O ALQUILALOIRO QUE SE PUEDE SUSTITUIR OPCIONALMENTE POR HALOGENO O C1-6-ALCOXI; R4 Y R5 INDEPENDIENTEMENTE SON HIDROGENO, HALOGENO, C1-6-ALQUILO O TRIFLUOROMETILO. LOS COMPUESTOS SON UTILES EN PREPARACIONES FARMACEUTICAS TALES COMO ANTICONVULSIVOS, ANSIOLITICOS, HIPNOTICOS Y AL MEJORAR LA FUNCION COGNITIVA DEL CEREBRO DE LOS MAMIFEROS.
ES90917143T 1989-11-22 1990-11-22 Compuestos de imidazoquinoxalina, su preparacion y uso. Expired - Lifetime ES2055454T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK588389A DK588389D0 (da) 1989-11-22 1989-11-22 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
ES2055454T3 true ES2055454T3 (es) 1994-08-16

Family

ID=8145913

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90917143T Expired - Lifetime ES2055454T3 (es) 1989-11-22 1990-11-22 Compuestos de imidazoquinoxalina, su preparacion y uso.

Country Status (19)

Country Link
US (1) US5102885A (es)
EP (1) EP0502885B1 (es)
JP (1) JPH05503084A (es)
KR (1) KR920703593A (es)
AT (1) ATE106405T1 (es)
AU (1) AU645508B2 (es)
CA (1) CA2073046A1 (es)
DE (1) DE69009493T2 (es)
DK (2) DK588389D0 (es)
ES (1) ES2055454T3 (es)
FI (1) FI97228C (es)
HU (1) HUT63420A (es)
IE (1) IE69960B1 (es)
IL (1) IL96372A (es)
NO (1) NO300064B1 (es)
NZ (1) NZ236156A (es)
PT (1) PT95972B (es)
WO (1) WO1991007408A1 (es)
ZA (1) ZA909304B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) * 1987-12-08 1991-10-14 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
FR2659329B1 (fr) * 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
DK588389D0 (da) 1989-11-22
HU9201709D0 (en) 1992-09-28
IL96372A0 (en) 1991-08-16
IL96372A (en) 1994-10-21
PT95972A (pt) 1991-09-13
EP0502885A1 (en) 1992-09-16
NO300064B1 (no) 1997-04-01
DK0502885T3 (da) 1994-09-26
DE69009493T2 (de) 1994-12-08
FI97228C (fi) 1996-11-11
DE69009493D1 (de) 1994-07-07
NZ236156A (en) 1993-01-27
ATE106405T1 (de) 1994-06-15
FI922269A0 (fi) 1992-05-19
ZA909304B (en) 1991-09-25
WO1991007408A1 (en) 1991-05-30
JPH05503084A (ja) 1993-05-27
KR920703593A (ko) 1992-12-18
NO921886D0 (no) 1992-05-13
HUT63420A (en) 1993-08-30
EP0502885B1 (en) 1994-06-01
FI922269A (fi) 1992-05-19
PT95972B (pt) 1998-01-30
FI97228B (fi) 1996-07-31
IE69960B1 (en) 1996-10-16
CA2073046A1 (en) 1991-05-23
AU645508B2 (en) 1994-01-20
AU6742990A (en) 1991-06-13
IE904157A1 (en) 1991-05-22
NO921886L (no) 1992-05-13
US5102885A (en) 1992-04-07

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