ES2054282T3 - Composiciones aerosoles destinadas a la imaginologia, al diagnostico y a la terapia selectiva de focos inflamatorios y tumorales. - Google Patents

Composiciones aerosoles destinadas a la imaginologia, al diagnostico y a la terapia selectiva de focos inflamatorios y tumorales.

Info

Publication number
ES2054282T3
ES2054282T3 ES90400628T ES90400628T ES2054282T3 ES 2054282 T3 ES2054282 T3 ES 2054282T3 ES 90400628 T ES90400628 T ES 90400628T ES 90400628 T ES90400628 T ES 90400628T ES 2054282 T3 ES2054282 T3 ES 2054282T3
Authority
ES
Spain
Prior art keywords
inflammatory
compound
imaginology
diagnosis
compositions intended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90400628T
Other languages
English (en)
Inventor
D Hinterland Lucien Dussourd
Pape Alain Le
Gerard Normier
Anne-Marie Pinel
Jacques Durand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Application granted granted Critical
Publication of ES2054282T3 publication Critical patent/ES2054282T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Atmospheric Sciences (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

LA PRESENTE INVENCION TIENE POR OBJETO UNA COMPOSICION DE AEROSOL QUE CONTIENE UN AGENTE VECTOR CAPAZ DE RECONOCER Y FIJARSE SOBRE LOS FOCOS INFLAMATORIOS Y TUMORALES, MOVILIZANDO EN SU ENTORNO PROXIMO MACROFAGOS, Y UN SUBSTRATO AEROSOL, CARACTERIZADO PORQUE DICHO AGENTE VECTOR CONSISTE EN UN COMPUESTO POLISACARIDO, ELEGIDO ENTRE EL COMPUESTO D 25 EXTRACTO DE PROTEOGLICANOS MEMBRANARIOS DE LA BACTERIA KLEBSIELLA PNEUMONIAE, Y QUE TIENE UN PESO MOLECULAR DE 30 +- 10 KD, Y EL COMPUESTO D 25 OXIDADO EN EL QUE EL RESIDUO GALACTO FURANOSA (GALF) DE LA CADENA POLISACARIDA LINEAL DEL D 25 HA SIDO TRANSFORMADA EN ARABINOSA, Y SUS DERIVADOS DE TIPO AMIDA, ESTER O ETER, ASI COMO SUS SALES Y DERIVADOS DE AMONIO CUATERNARIOS, ASI COMO LOS DERIVADOS OBTENIDOS POR INJERTO DE FOSFATIDOS.
ES90400628T 1989-03-08 1990-03-08 Composiciones aerosoles destinadas a la imaginologia, al diagnostico y a la terapia selectiva de focos inflamatorios y tumorales. Expired - Lifetime ES2054282T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR898903034A FR2644059B1 (fr) 1989-03-08 1989-03-08 Compositions aerosols destinees a l'imagerie, au diagnostic et a la therapie ciblee de foyers inflammatoires et tumoraux

Publications (1)

Publication Number Publication Date
ES2054282T3 true ES2054282T3 (es) 1994-08-01

Family

ID=9379492

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90400628T Expired - Lifetime ES2054282T3 (es) 1989-03-08 1990-03-08 Composiciones aerosoles destinadas a la imaginologia, al diagnostico y a la terapia selectiva de focos inflamatorios y tumorales.

Country Status (10)

Country Link
US (1) US5362474A (es)
EP (1) EP0387154B1 (es)
JP (1) JPH03236332A (es)
AT (1) ATE88643T1 (es)
AU (1) AU626645B2 (es)
CA (1) CA2011772A1 (es)
DE (1) DE69001454T2 (es)
DK (1) DK0387154T3 (es)
ES (1) ES2054282T3 (es)
FR (1) FR2644059B1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3320734B2 (ja) * 1993-07-28 2002-09-03 ダイアタイド・インコーポレイテッド 放射性同位体標識したグルカン類
US5406950A (en) * 1993-12-23 1995-04-18 Mallinckrodt Medical, Inc. Inhalable contrast agent
DE19529921C2 (de) * 1995-08-01 1997-09-25 Schering Ag Verwendung von MRT-Kontrastmitteln zur Ventilations-Bildgebung der Lunge
CA2215152A1 (en) * 1996-01-12 1997-07-17 Redcell Canada, Inc. Cellular and serum protein anchors for diagnostic imaging
GB9710604D0 (en) * 1997-05-22 1997-07-16 Nycomed Imaging As Contrast media

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929994A (en) * 1969-05-20 1975-12-30 Roussel Uclaf Anti-inflammatory glycoprotein compositions and method of use
US3885197A (en) * 1974-02-01 1975-05-20 Lear Siegler Inc Light dimmer
FR2546756B1 (fr) * 1983-06-03 1985-11-29 Centre Nat Rech Scient Nouveaux derives immunostimulants, leur preparation et leur application comme medicament
EP0142641B1 (de) * 1983-09-26 1991-01-16 Udo Dr. Ehrenfeld Mittel und Erzeugnis für die Diagnose und Therapie von Tumoren sowie zur Behandlung von Schwächen der zelligen und humoralen Immunabwehr
FR2570081B1 (fr) * 1984-09-10 1987-01-09 Pf Medicament Polysaccharides membranaires utiles notamment comme medicament et procede pour leur preparation
FR2598434B1 (fr) * 1986-05-12 1988-09-16 Pf Medicament Nouveaux immunomodulateurs obtenus par hemisynthese a partir d'un polysaccharide bacterien isole d'une souche mutante non capsulee de klebsiella pneumoniae
FR2614306B1 (fr) * 1987-04-22 1989-07-28 Pf Medicament Nouveau derive de d.25, procede de preparation, utilisation a titre d'agent immunostimulant et compositions pharmaceutiques le contenant.

Also Published As

Publication number Publication date
DE69001454T2 (de) 1993-08-26
DK0387154T3 (da) 1993-05-24
FR2644059A1 (fr) 1990-09-14
EP0387154A1 (fr) 1990-09-12
US5362474A (en) 1994-11-08
AU5111490A (en) 1990-09-13
ATE88643T1 (de) 1993-05-15
JPH03236332A (ja) 1991-10-22
DE69001454D1 (de) 1993-06-03
CA2011772A1 (fr) 1990-09-08
EP0387154B1 (fr) 1993-04-28
AU626645B2 (en) 1992-08-06
FR2644059B1 (fr) 1994-03-04

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