ES2053655T3 - Un procedimiento para preparar un derivado de acido penicilanico. - Google Patents

Un procedimiento para preparar un derivado de acido penicilanico.

Info

Publication number
ES2053655T3
ES2053655T3 ES88114620T ES88114620T ES2053655T3 ES 2053655 T3 ES2053655 T3 ES 2053655T3 ES 88114620 T ES88114620 T ES 88114620T ES 88114620 T ES88114620 T ES 88114620T ES 2053655 T3 ES2053655 T3 ES 2053655T3
Authority
ES
Spain
Prior art keywords
acid derivative
preparing
procedure
penicilanic acid
penicilanic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88114620T
Other languages
English (en)
Inventor
Masatoshi C O Otsuga Taniguchi
Michio C O Otsuka Kaga Sasaoka
Kiyotoshi C O Otsuka Matsumura
Ichiro C O Otsuka Kag Kawahara
Kenji C O Otsuka Kagaku K Kase
Daisuke C O Otsuka Kaga Susuki
Shigeru Torii
Hideo Tanaka
Motoaki Tanaka
Akira Nakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Taiho Pharmaceutical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd, Taiho Pharmaceutical Co Ltd filed Critical Otsuka Chemical Co Ltd
Application granted granted Critical
Publication of ES2053655T3 publication Critical patent/ES2053655T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL PRESENTE INVENTO PROVEE UN PROCESO PARA PREPARAR UN DERIVADO DE ACIDO PENICILINICO DE LA FORMULA (II) QUE COMPRENDE PLOMO QUE REACCIONA CON UNDERIVADO DE ACIDO PENICILINICO HALOGENADO DE LA FORMULA (I) EN DONDE X, Y, Z Y R1 SON DEFINIDOS EN LA ESPECIFICACION. LA REACCION ES CONDUCIDA MAS VENTAJOSAMENTE EN LA PRESENCIA DE UN METAL QUE TIENE TENDENCIA DE IONIZACION MAS GRANDE QUE EL PLOMO.
ES88114620T 1987-09-07 1988-09-07 Un procedimiento para preparar un derivado de acido penicilanico. Expired - Lifetime ES2053655T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62224589A JP2603082B2 (ja) 1987-09-07 1987-09-07 ペニシラン酸誘導体の製造法

Publications (1)

Publication Number Publication Date
ES2053655T3 true ES2053655T3 (es) 1994-08-01

Family

ID=16816096

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88114620T Expired - Lifetime ES2053655T3 (es) 1987-09-07 1988-09-07 Un procedimiento para preparar un derivado de acido penicilanico.

Country Status (7)

Country Link
US (1) US4912213A (es)
EP (1) EP0306924B1 (es)
JP (1) JP2603082B2 (es)
AU (1) AU609870B2 (es)
CA (1) CA1297870C (es)
DE (1) DE3879049T2 (es)
ES (1) ES2053655T3 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
DE69225821T2 (de) * 1991-03-13 1998-11-05 Otsuka Kagaku Kk Penamderivate und Verfahren zu deren Herstellung
WO1999033838A1 (en) 1997-12-29 1999-07-08 Research Corporation Technologies, Inc. 2-β-SUBSTITUTED-6-ALKYLIDENE PENICILLANIC ACID DERIVATIVES AS β-LACTAMASE INHIBITORS
ATE288438T1 (de) * 1999-03-03 2005-02-15 Astur Pharma Sa Verfahren zur herstellung von dioxopenicillansäurederivaten
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
JP3743822B2 (ja) * 2000-08-11 2006-02-08 大塚化学ホールディングス株式会社 ペニシリン結晶及びその製造法
ATE339424T1 (de) 2001-07-24 2006-10-15 Univ Southern Methodist 3-substituierte 7-alkylidene-3-cephem-4- carbonsäuren als beta-lactamase inhibitoren
US7022691B2 (en) 2002-04-04 2006-04-04 John D. Buynak Inhibitors of serine and metallo-β-lactamases
CA2487883C (en) 2002-06-07 2011-04-19 Orchid Chemicals & Pharmaceuticals Limited Process for preparation of penam derivatives from cepham derivatives
TW200519119A (en) * 2003-10-10 2005-06-16 Otsuka Chemical Co Ltd PENAM crystal and process for producing the same
US20060173177A1 (en) * 2005-01-28 2006-08-03 Gego Csaba L Process for preparation of penam derivatives
CN103044447B (zh) * 2013-01-16 2014-12-17 江西富祥药业股份有限公司 一种青霉烷亚砜酸二苯甲酯的制备方法
CN109503627A (zh) * 2018-11-28 2019-03-22 齐鲁天和惠世制药有限公司 一种他唑巴坦中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656263A (en) * 1979-03-05 1987-04-07 Pfizer Inc. 6-β-substituted penicillanic acid compound free of the 6-α-epimer
US4762920A (en) * 1979-03-05 1988-08-09 Pfizer, Inc. 6,6-Dihalopenicillanic acid 1,1-dioxides
FI67553C (fi) * 1980-01-21 1985-04-10 Bristol Myers Co Foerfarande foer framstaellning av en terapeutiskt anvaendbar 2beta-klormetyl-2alfa-metylpenam-3alfa-karboxylsyrasulfon sater och estrar daerav
JPS58185589A (ja) * 1982-04-23 1983-10-29 Taiho Yakuhin Kogyo Kk ペニシリン誘導体
AU541028B2 (en) * 1982-06-21 1984-12-13 Taiho Pharmaceutical Co., Ltd. 6-unsubstituted penicillin derivatives
EP0139048A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
EP0306924A1 (en) 1989-03-15
US4912213A (en) 1990-03-27
DE3879049T2 (de) 1993-10-07
JPS6466189A (en) 1989-03-13
DE3879049D1 (de) 1993-04-15
AU2192188A (en) 1989-03-09
JP2603082B2 (ja) 1997-04-23
AU609870B2 (en) 1991-05-09
CA1297870C (en) 1992-03-24
EP0306924B1 (en) 1993-03-10

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