ES2053257T3 - Derivados de pradimicina. - Google Patents

Derivados de pradimicina.

Info

Publication number
ES2053257T3
ES2053257T3 ES91116628T ES91116628T ES2053257T3 ES 2053257 T3 ES2053257 T3 ES 2053257T3 ES 91116628 T ES91116628 T ES 91116628T ES 91116628 T ES91116628 T ES 91116628T ES 2053257 T3 ES2053257 T3 ES 2053257T3
Authority
ES
Spain
Prior art keywords
sub
beta
methyl
glucosil
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91116628T
Other languages
English (en)
Inventor
Shimpei Aburaki
Haruhuro Yamashita
Takayuki Naito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2053257T3 publication Critical patent/ES2053257T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS COMPUESTOS ANTIFUNGALES QUE TIENEN LA FORMULA EN LA QUE R SUB 1 ES HIDROGENO, METIL, O HIDROXIMETIL; R SUB 2 Y R SUB 3 ESTAN INDEPENDIENTEMENTE SELECCIONADOS ENTRE EL GRUPO QUE CONSTA DE HIDROGENO Y ALQUIL C SUB 1-C SUB 5; Y R SUB 4 SE SELECCIONA DEL GRUPO QUE CONSTA DE (BETA)-L-XILOSIL; (BETA)-D-RIBOSIL, (ALFA)-L-ARABINOSIL, (BETA)-D-CHINOVOSIL, (BETA)-D-FUCOSIL, Y (BETA)-D-GLUCOSIL; CON LA CONDICION DE QUE CUANDO R SUB 1 SEA METIL O HIDROXIMETIL, Y UNA DE R SUB 2 O R SUB 3 SEA METIL, R SUB 4 NO SERA (BETA)-D-GLUCOSIL; ASI MISMO SE PRESENTAN LAS SALES FARMACEUTICAMENTE LAS SALES DE LOS MENCIONADOS COMPUESTOS.
ES91116628T 1990-09-28 1991-09-27 Derivados de pradimicina. Expired - Lifetime ES2053257T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/590,621 US5696096A (en) 1990-09-28 1990-09-28 Pradimicin derivatives

Publications (1)

Publication Number Publication Date
ES2053257T3 true ES2053257T3 (es) 1994-07-16

Family

ID=24362965

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91116628T Expired - Lifetime ES2053257T3 (es) 1990-09-28 1991-09-27 Derivados de pradimicina.

Country Status (8)

Country Link
US (1) US5696096A (es)
EP (1) EP0479175B1 (es)
JP (1) JPH04282396A (es)
AT (1) ATE105565T1 (es)
CA (1) CA2052020C (es)
DE (1) DE69101960T2 (es)
DK (1) DK0479175T3 (es)
ES (1) ES2053257T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960755A (en) * 1988-07-19 1990-10-02 Bristol-Myers Company BU-3608 derivatives
JP3134010B2 (ja) * 1991-11-26 2001-02-13 財団法人微生物化学研究会 デスアラニンベナノマイシンａ誘導体およびそれらの製造法
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5733647A (en) * 1992-11-05 1998-03-31 Polymer Innovations, Inc. Insole
CN104817604B (zh) * 2015-03-16 2017-08-04 邦泰生物工程(深圳)有限公司 一种β‑烟酰胺单核苷酸的纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130709A (en) * 1977-12-08 1978-12-19 Eli Lilly And Company Pleuromutilin glycoside derivatives
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics
US5055453A (en) * 1987-11-02 1991-10-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Benanomicins a and antibiotic compositions
US4992425A (en) * 1988-06-07 1991-02-12 Bristol-Myers Company Antibiotics BU-3608D and BU-3608E
US4960755A (en) * 1988-07-19 1990-10-02 Bristol-Myers Company BU-3608 derivatives
US4973673A (en) * 1988-11-10 1990-11-27 Bristol-Myers Company Serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
US5053395A (en) * 1989-03-24 1991-10-01 Bristol-Myers Company Pradimicin amide derivatives
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof

Also Published As

Publication number Publication date
ATE105565T1 (de) 1994-05-15
JPH04282396A (ja) 1992-10-07
CA2052020A1 (en) 1992-03-29
DE69101960T2 (de) 1994-09-22
DE69101960D1 (de) 1994-06-16
DK0479175T3 (da) 1994-06-13
EP0479175B1 (en) 1994-05-11
CA2052020C (en) 2002-02-26
EP0479175A1 (en) 1992-04-08
US5696096A (en) 1997-12-09

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