ES2049254T3 - Aparato y procedimiento para la dilucion y mezcla de muestras liquidas. - Google Patents
Aparato y procedimiento para la dilucion y mezcla de muestras liquidas.Info
- Publication number
- ES2049254T3 ES2049254T3 ES88307946T ES88307946T ES2049254T3 ES 2049254 T3 ES2049254 T3 ES 2049254T3 ES 88307946 T ES88307946 T ES 88307946T ES 88307946 T ES88307946 T ES 88307946T ES 2049254 T3 ES2049254 T3 ES 2049254T3
- Authority
- ES
- Spain
- Prior art keywords
- chamber
- sample
- mixing
- application
- relation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
- G01N33/04—Dairy products
Abstract
APARATO PARA DILUIR UNA MUESTRA CON UN DILUYENTE, QUE CONSTA DE UNA CAMARA MEDIDORA DE VOLUMEN FIJO, UNA CAMARA RECEPTORA DE VOLUMEN FIJO EN COMUNICACION CON LA ANTERIOR, UN ORIFICIO DE AIREACION DE GAS EN LA CAMARA DE RECEPCION, UNA CONEXION DE DETENCION DEL FLUJO ENTRE LA CAMARA MEDIDORA Y LA RECEPTORA, UN PUNTO DE APLICACION DE LA MUESTRA EN RELACION CON LA CAMARA DE MEDICION, SIENDO LA DIFERENCIA DE ALTURA ENTRE EL LUGAR DE APLICACION DE LA MUESTRA Y LA CONEXION INSUFICIENTE PARA QUE APAREZCA UNA PRESION HIDROSTATICA CAPAZ DE SUPERAR LA CONTRAPRESION EN LA CONEXION CUANDO LA MUESTRA SE APLICA, ASI COMO EL DILUYENTE EN RELACION CON LA CAMARA DE MEDICION. LA MUESTRA Y EL DISOLVENTE SE AÑADEN SECUENCIALMENTE AL APARATO PARA CONSEGUIR LA DISOLUCION SIN NECESIDAD DE OTRAS OPERACIONES. EN UN SEGUNDO DISEÑO, UN CARTUCHO DE DILUCION Y MEZCLA CONSTA DE UN PUNTO DE APLICACION DE LA MUESTRA, UNA CAMARA MEZCLADORA EN RELACION CON EL ANTERIOR, UN PUNTO DE APLICACION DEL DISOLVENTE EN RELACION CONLA CAMARA DE MEZCLA, UNA CAMARA DE AISLAMIENTO DE LA MEZCLA CONECTADA HIDROSTATICAMENTE A LA DE MEZCLADO, UNA PRIMERA VALVULA QUE IMPIDE DE FORMA SELECTIVA LA CIRCULACION DESDE EL PUNTO DE APLICACION DE DISOLVENTE A LA CAMARA DE MEZCLADO Y UNA CAMARA DE AISLANTE DE LA MEZCLA CONECTADA HIDROSTATICAMENTE A LA CAMARA DE MEZCLA. EL INVENTO INCLUYE IGUALMENTE UN METODO PARA UTILIZAR ESTE CARTUCHO PARA DILUIR SECUENCIALMENTE UNA MUESTRA CON UNO O VARIOS DILUYENTES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/090,026 US4868129A (en) | 1987-08-27 | 1987-08-27 | Apparatus and method for dilution and mixing of liquid samples |
US07/117,791 US5077017A (en) | 1987-11-05 | 1987-11-05 | Integrated serial dilution and mixing cartridge |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2049254T3 true ES2049254T3 (es) | 1994-04-16 |
Family
ID=26781444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88307946T Expired - Lifetime ES2049254T3 (es) | 1987-08-27 | 1988-08-26 | Aparato y procedimiento para la dilucion y mezcla de muestras liquidas. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0305210B1 (es) |
JP (1) | JPH0756492B2 (es) |
AU (1) | AU615208B2 (es) |
CA (1) | CA1333850C (es) |
DE (1) | DE3886140T2 (es) |
ES (1) | ES2049254T3 (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5104813A (en) * | 1989-04-13 | 1992-04-14 | Biotrack, Inc. | Dilution and mixing cartridge |
US5225163A (en) * | 1989-08-18 | 1993-07-06 | Angenics, Inc. | Reaction apparatus employing gravitational flow |
WO1991002589A1 (en) * | 1989-08-18 | 1991-03-07 | Cambridge Bioscience Corporation | Reaction apparatus and method employing gravitational flow |
US5230866A (en) * | 1991-03-01 | 1993-07-27 | Biotrack, Inc. | Capillary stop-flow junction having improved stability against accidental fluid flow |
EP0501796A3 (en) * | 1991-03-01 | 1993-10-06 | Biotrack, Inc. | Capillary stop-flow junction having improved stability against accidental fluid flow |
EP0865606B1 (en) * | 1995-12-05 | 2005-03-16 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
EP1577010A3 (en) * | 1995-12-05 | 2005-11-16 | Tecan Trading AG | Microsystem platform and its use |
US6709869B2 (en) | 1995-12-18 | 2004-03-23 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
US6143248A (en) * | 1996-08-12 | 2000-11-07 | Gamera Bioscience Corp. | Capillary microvalve |
WO1998028623A1 (en) * | 1996-12-20 | 1998-07-02 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
US6632399B1 (en) | 1998-05-22 | 2003-10-14 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays |
JP3469585B2 (ja) | 1997-05-23 | 2003-11-25 | ガメラ バイオサイエンス コーポレイション | ミクロ流体工学システムでの流動運動を駆動するために向心的加速を使用するための装置および方法 |
AU9020698A (en) | 1997-08-15 | 1999-03-08 | Alexion Pharmaceuticals, Inc. | Apparatus for performing assays at reaction sites |
SE9803734D0 (sv) | 1998-10-30 | 1998-10-30 | Amersham Pharm Biotech Ab | Liquid handling system |
US6193471B1 (en) * | 1999-06-30 | 2001-02-27 | Perseptive Biosystems, Inc. | Pneumatic control of formation and transport of small volume liquid samples |
DE60034479T2 (de) * | 1999-11-15 | 2007-12-27 | I-Stat Corporation | Vorrichtung und verfahren zum bestimmen der koagulation in flüssigproben |
DE10057895B4 (de) * | 2000-11-22 | 2009-06-18 | peS Gesellschaft für medizinische Diagnosesysteme mbH | Vorrichtung und Verfahren zur Probenvorbereitung flüssiger Proben |
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
EP1483052B1 (en) | 2001-08-28 | 2010-12-22 | Gyros Patent Ab | Retaining microfluidic microcavity and other microfluidic structures |
US6919058B2 (en) | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
US20030198576A1 (en) * | 2002-02-22 | 2003-10-23 | Nanostream, Inc. | Ratiometric dilution devices and methods |
JP4210783B2 (ja) | 2002-09-26 | 2009-01-21 | アークレイ株式会社 | 分析用具 |
DE102004022423A1 (de) * | 2004-05-06 | 2005-12-15 | Siemens Ag | Mikrofluidiksystem |
JP4660662B2 (ja) * | 2005-09-06 | 2011-03-30 | アークレイ株式会社 | カートリッジ |
JP2007003414A (ja) * | 2005-06-24 | 2007-01-11 | Arkray Inc | 分析装置用カートリッジ |
JP4797619B2 (ja) * | 2005-12-22 | 2011-10-19 | 東レ株式会社 | 分析チップおよび被検物質の分析方法 |
JP5241209B2 (ja) * | 2007-11-26 | 2013-07-17 | 株式会社日立ハイテクノロジーズ | 試料前処理用デバイス及び試料分析方法 |
US9040285B2 (en) | 2008-12-18 | 2015-05-26 | Koninklijkle Philips N.V. | Sensing device for sensing a fluid |
JP5888885B2 (ja) * | 2010-06-23 | 2016-03-22 | アークレイ株式会社 | 測定装置、測定方法、測定プログラム、および測定システム |
CN104813170B (zh) * | 2012-11-15 | 2017-11-24 | 安捷伦科技有限公司 | 到可指定的稀释率的样品稀释 |
JP5833716B1 (ja) * | 2014-07-24 | 2015-12-16 | 日本電信電話株式会社 | 血液凝固検査方法および血液凝固検査用流路チップ |
AU2017212754B2 (en) | 2016-01-29 | 2023-06-29 | Purigen Biosystems, Inc. | Isotachophoresis for purification of nucleic acids |
JP7289792B2 (ja) * | 2017-04-21 | 2023-06-12 | メサ バイオテック,インク. | 流体検査用カセット |
SG11202000871WA (en) * | 2017-08-02 | 2020-02-27 | Purigen Biosystems Inc | Systems, devices, and methods for isotachophoresis |
CN117109990A (zh) * | 2018-02-27 | 2023-11-24 | 芯易诊有限公司 | 获得定量样品混合物的装置及方法 |
CN108393105B (zh) * | 2018-04-20 | 2023-08-25 | 华南师范大学 | 一种微流控芯片及其控制系统、控制方法 |
WO2020149067A1 (ja) * | 2019-01-17 | 2020-07-23 | 日本分光株式会社 | スタティックミキサー |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE330624B (es) * | 1965-09-02 | 1970-11-23 | Medicinskkemiska Lab Calab Ab | |
US3799742A (en) * | 1971-12-20 | 1974-03-26 | C Coleman | Miniaturized integrated analytical test container |
US3869068A (en) * | 1974-06-06 | 1975-03-04 | Hyperion Inc | Diluter probe assembly |
US4426451A (en) * | 1981-01-28 | 1984-01-17 | Eastman Kodak Company | Multi-zoned reaction vessel having pressure-actuatable control means between zones |
US4503012A (en) * | 1983-04-19 | 1985-03-05 | American Monitor Corporation | Reagent dispensing system |
FI834387A0 (fi) * | 1983-11-30 | 1983-11-30 | Labsystems Oy | Foerfarande foer utspaedning av vaetskeprov |
-
1988
- 1988-08-26 EP EP88307946A patent/EP0305210B1/en not_active Expired - Lifetime
- 1988-08-26 CA CA000575875A patent/CA1333850C/en not_active Expired - Fee Related
- 1988-08-26 ES ES88307946T patent/ES2049254T3/es not_active Expired - Lifetime
- 1988-08-26 DE DE3886140T patent/DE3886140T2/de not_active Expired - Fee Related
- 1988-08-27 JP JP63213515A patent/JPH0756492B2/ja not_active Expired - Lifetime
- 1988-08-29 AU AU21639/88A patent/AU615208B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0305210A3 (en) | 1989-10-11 |
AU2163988A (en) | 1989-03-02 |
EP0305210B1 (en) | 1993-12-08 |
DE3886140T2 (de) | 1994-05-19 |
AU615208B2 (en) | 1991-09-26 |
EP0305210A2 (en) | 1989-03-01 |
JPH0756492B2 (ja) | 1995-06-14 |
CA1333850C (en) | 1995-01-10 |
JPH01257268A (ja) | 1989-10-13 |
DE3886140D1 (de) | 1994-01-20 |
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