ES2046107A1 - Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina. - Google Patents
Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina.Info
- Publication number
- ES2046107A1 ES2046107A1 ES9200500A ES9200500A ES2046107A1 ES 2046107 A1 ES2046107 A1 ES 2046107A1 ES 9200500 A ES9200500 A ES 9200500A ES 9200500 A ES9200500 A ES 9200500A ES 2046107 A1 ES2046107 A1 ES 2046107A1
- Authority
- ES
- Spain
- Prior art keywords
- hetero
- methyl piperazine
- cycloalkenyl
- cycloalkyl
- phenyl methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
SE DESCRIBE LA PREPARACION DE NUEVOS DERIVADOS DE LA DIFENILMETILPIPERACINA DE FORMULA: FORMULA EN DONDE A ES UN GRUPO CARBONILO O ALQUILAMINOCARBONILO Y B ES UN GRUPO HETEROARILO, SUSTITUIDO O NO, CICLOALQUILO O CICLOALQUENILO, ASI COMO SUS SALES DE ADICION FARMACEUTICAMENTE ESTABLES. LOS NUEVOS DERIVADOS SE SINTETIZAN HACIENDO REACCIONAR LA DIFENILMETILPIPERACINA, O UN DERIVADO ALQUILENAMINO DE LA MISMA, CON UN CLORURO DE UN ACIDO HETEROAROMATICO, EN EL QUE EL HETEROATOMO ES PREFERENTEMENTE UN NITROGENO Y QUE ESTA SUSTITUIDO POR UN HALOGENO, PREFERENTEMENTE CLORO O BROMO; O CON EL CLORURO DE UN ACIDO BICICLOALCANOICO O ALQUENOICO. ESTOS COMPUESTOS PRESENTAN ACTIVIDAD FARMACOLOGICA, EN PARTICULAR ANTIHISTAMINICA Y ANTIALERGICA.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200500A ES2046107B1 (es) | 1992-03-05 | 1992-03-05 | Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200500A ES2046107B1 (es) | 1992-03-05 | 1992-03-05 | Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2046107A1 true ES2046107A1 (es) | 1994-01-16 |
ES2046107B1 ES2046107B1 (es) | 1994-08-01 |
Family
ID=8276315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9200500A Expired - Fee Related ES2046107B1 (es) | 1992-03-05 | 1992-03-05 | Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2046107B1 (es) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3267104A (en) * | 1964-06-09 | 1966-08-16 | Janssen Pharmaceutica Nv | 1, 4-disubstituted piperazines and diazepines |
ES8203870A1 (es) * | 1980-06-16 | 1982-04-01 | Ferrosan Ab | Procedimiento para preparar difenilbutil-1-acilpiperazinas |
EP0210782A2 (en) * | 1985-07-19 | 1987-02-04 | Dainippon Pharmaceutical Co., Ltd. | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same |
EP0343961A2 (en) * | 1988-05-24 | 1989-11-29 | American Home Products Corporation | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity |
-
1992
- 1992-03-05 ES ES9200500A patent/ES2046107B1/es not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3267104A (en) * | 1964-06-09 | 1966-08-16 | Janssen Pharmaceutica Nv | 1, 4-disubstituted piperazines and diazepines |
ES8203870A1 (es) * | 1980-06-16 | 1982-04-01 | Ferrosan Ab | Procedimiento para preparar difenilbutil-1-acilpiperazinas |
EP0210782A2 (en) * | 1985-07-19 | 1987-02-04 | Dainippon Pharmaceutical Co., Ltd. | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same |
EP0343961A2 (en) * | 1988-05-24 | 1989-11-29 | American Home Products Corporation | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity |
Also Published As
Publication number | Publication date |
---|---|
ES2046107B1 (es) | 1994-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19991102 |