ES2039265T3 - Procedimiento mejorado para la preparacion de benzo-(calcogeno) (4,3,2-cd)indazoles. - Google Patents

Procedimiento mejorado para la preparacion de benzo-(calcogeno) (4,3,2-cd)indazoles.

Info

Publication number
ES2039265T3
ES2039265T3 ES198888104592T ES88104592T ES2039265T3 ES 2039265 T3 ES2039265 T3 ES 2039265T3 ES 198888104592 T ES198888104592 T ES 198888104592T ES 88104592 T ES88104592 T ES 88104592T ES 2039265 T3 ES2039265 T3 ES 2039265T3
Authority
ES
Spain
Prior art keywords
calcogen
benzo
indazoles
preparation
improved procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888104592T
Other languages
English (en)
Inventor
Vladimir Genukh Beylin
Om Prakash Goel
Anthony Denver Sercel
Howard Daniel Hollis Showalter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2039265T3 publication Critical patent/ES2039265T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCESOS MEJORADOS PARA PRODUCIR BENZO(CALCOGENO) [4,3,2-CD] INDAZOLES SUSTITUIDOS. LOS PROCESOS PRODUCEN COMPUESTOS CON GRAN RENDIMIENTO Y DE MAYOR PUREZA USANDO UNA NUEVA SECUENCIA DE QUIMICA DE ACILACION Y GRUPOS DE PROTECCION FACILMENTE SEPARABLES. LOS COMPUESTOS PRODUCIDOS TIENEN ACTIVIDAD ANTIBACTERIANA, ANTIFUNGICA, ANTILEUCEMICA Y ANTITUMORAL.
ES198888104592T 1987-03-23 1988-03-22 Procedimiento mejorado para la preparacion de benzo-(calcogeno) (4,3,2-cd)indazoles. Expired - Lifetime ES2039265T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2902187A 1987-03-23 1987-03-23
US07/149,103 US4806654A (en) 1987-03-23 1988-02-11 Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof

Publications (1)

Publication Number Publication Date
ES2039265T3 true ES2039265T3 (es) 1993-09-16

Family

ID=26704423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888104592T Expired - Lifetime ES2039265T3 (es) 1987-03-23 1988-03-22 Procedimiento mejorado para la preparacion de benzo-(calcogeno) (4,3,2-cd)indazoles.

Country Status (15)

Country Link
US (1) US4806654A (es)
EP (1) EP0284966B1 (es)
JP (1) JP2648165B2 (es)
KR (1) KR960001477B1 (es)
AU (1) AU605551B2 (es)
DE (1) DE3867280D1 (es)
DK (1) DK174623B1 (es)
ES (1) ES2039265T3 (es)
FI (1) FI93730C (es)
GR (1) GR3003513T3 (es)
IE (1) IE61090B1 (es)
NO (1) NO171161C (es)
NZ (1) NZ223761A (es)
PH (1) PH25229A (es)
PT (1) PT87040B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ303528A (en) * 1995-02-27 1998-08-26 Sanofi Winthrop Inc Benzothiopyran[4,3,2-cd]indazole derivatives and medicaments
US6747039B2 (en) 2002-03-12 2004-06-08 Albany Molecular Research, Inc. Aza-benzothiopyranoindazoles with antitumor activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1381442A (en) * 1972-05-02 1975-01-22 Searle & Co Process for the preparation of prostaglandin precursors
CH577464A5 (es) * 1972-09-22 1976-07-15 Ciba Geigy Ag
JPS559517B2 (es) * 1973-07-16 1980-03-10
CA1206153A (en) * 1983-01-06 1986-06-17 Donald F. Worth Benzothiopyrano ¬4,3,2-cd| indazole compositions and methods for their production and use
US4604390A (en) * 1983-01-06 1986-08-05 Warner-Lambert Company Antibacterial benzo(chalcogeno)[4,3,2-cd]indazoles
CA1251450A (en) * 1984-06-29 1989-03-21 David B. Capps Benzopyrano¬4,3,2-cd|indazole compositions and methods for their production and use
CA1251451A (en) * 1984-06-29 1989-03-21 Ellen M. Berman Benzoseleno¬4,3,2-cd|indazole compositions and methods for their production and use

Also Published As

Publication number Publication date
JPS646277A (en) 1989-01-10
NO171161B (no) 1992-10-26
NZ223761A (en) 1990-10-26
DK156888A (da) 1988-09-24
IE61090B1 (en) 1994-09-21
FI93730B (fi) 1995-02-15
US4806654A (en) 1989-02-21
FI881327A0 (fi) 1988-03-21
DK156888D0 (da) 1988-03-22
NO171161C (no) 1993-02-03
NO881251D0 (no) 1988-03-22
DE3867280D1 (de) 1992-02-13
AU1212488A (en) 1988-09-22
AU605551B2 (en) 1991-01-17
JP2648165B2 (ja) 1997-08-27
DK174623B1 (da) 2003-07-28
PT87040A (pt) 1988-04-01
EP0284966A1 (en) 1988-10-05
IE880488L (en) 1988-09-23
FI93730C (fi) 1995-05-26
PT87040B (pt) 1992-07-31
KR880011156A (ko) 1988-10-26
PH25229A (en) 1991-03-27
FI881327A (fi) 1988-09-24
NO881251L (no) 1988-09-26
KR960001477B1 (ko) 1996-01-31
EP0284966B1 (en) 1992-01-02
GR3003513T3 (es) 1993-03-16

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