ES2037609A1 - Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol. - Google Patents

Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol.

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Publication number
ES2037609A1
ES2037609A1 ES919102694A ES9102694A ES2037609A1 ES 2037609 A1 ES2037609 A1 ES 2037609A1 ES 919102694 A ES919102694 A ES 919102694A ES 9102694 A ES9102694 A ES 9102694A ES 2037609 A1 ES2037609 A1 ES 2037609A1
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ES
Spain
Prior art keywords
methyl
prepn
benzimidazole
sulphinyl
pyridinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES919102694A
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English (en)
Other versions
ES2037609B1 (es
Inventor
Bernardo Julio Martin Alvarez
Amuriza Maria Victoria Montes
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TECHQUIN ETABLISSMENT
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TECHQUIN ETABLISSMENT
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Priority to ES9102694A priority Critical patent/ES2037609B1/es
Publication of ES2037609A1 publication Critical patent/ES2037609A1/es
Application granted granted Critical
Publication of ES2037609B1 publication Critical patent/ES2037609B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL 2-[[[3-METIL-4-2(2,2,2-TRIFLUOROETOXI)-2-PIRIDINIL]-METIL]SULFINIL]-1H-BENZIMIDAZOL. EL PROCEDIMIENTO CONSISTE EN SOMETER A UNA SUSTITUCION NUCLEOFILA EL 2-[[[3-METIL-4-BROMO-2-PIRIDINIL]-METIL]SULFINIL]-1H-BENZIMIZADOL, CON 2,2,2-TRIFLUOROETANOL, EN UN MEDIO BASICO, AISLANDO POR MEDIOS CONVENCIONALES Y FORMANDO POTESTATIVAMENTE SUS SALES DE ADICION CON ACIDOS O BASE, EFECTUANDOSE LA REACCION A UNA TEMPERATURA ENTRE 0GC Y LA DE REFLUJO, DE ACUERDO CON EL SIGUIENTE ESQUEMA: FORMULA
ES9102694A 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol. Expired - Lifetime ES2037609B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9102694A ES2037609B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9102694A ES2037609B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol.

Publications (2)

Publication Number Publication Date
ES2037609A1 true ES2037609A1 (es) 1993-06-16
ES2037609B1 ES2037609B1 (es) 1994-04-01

Family

ID=8274373

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9102694A Expired - Lifetime ES2037609B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol.

Country Status (1)

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ES (1) ES2037609B1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004109A1 (en) * 1999-07-14 2001-01-18 Quimica Sintetica, S.A. Process for the production of 2-(2-pyridinylmethylsulphinyl)-1h-benzimidazoles
ES2264362A1 (es) * 2004-12-22 2006-12-16 Laboratorios Viñas S.A. "procedimiento para la obtencion de derivados de 2-(2-piridinilmetilsufinil-1h-benzimidazoles".

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174988A (en) * 1983-02-11 1986-11-19 Haessle Ab Intermediates for pyridyl alkylthio-benzimidazole derivatives
ES2020494A6 (es) * 1990-07-25 1991-08-01 Union Quimico Farmaceutica, S.A. Procedimiento para obtener omeprazol.
ES2023609A6 (es) * 1990-11-29 1992-01-16 Inke Sa Procedimiento para la obtencion del 2-(((3-metil -4-(2,2,2-trifluoroetoxi) -2-piridinil) metilisulfinil) -1h-bemzimidazol.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174988A (en) * 1983-02-11 1986-11-19 Haessle Ab Intermediates for pyridyl alkylthio-benzimidazole derivatives
ES2020494A6 (es) * 1990-07-25 1991-08-01 Union Quimico Farmaceutica, S.A. Procedimiento para obtener omeprazol.
ES2023609A6 (es) * 1990-11-29 1992-01-16 Inke Sa Procedimiento para la obtencion del 2-(((3-metil -4-(2,2,2-trifluoroetoxi) -2-piridinil) metilisulfinil) -1h-bemzimidazol.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004109A1 (en) * 1999-07-14 2001-01-18 Quimica Sintetica, S.A. Process for the production of 2-(2-pyridinylmethylsulphinyl)-1h-benzimidazoles
ES2166269A1 (es) * 1999-07-14 2002-04-01 Sint Quimica Sa Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol.
ES2264362A1 (es) * 2004-12-22 2006-12-16 Laboratorios Viñas S.A. "procedimiento para la obtencion de derivados de 2-(2-piridinilmetilsufinil-1h-benzimidazoles".

Also Published As

Publication number Publication date
ES2037609B1 (es) 1994-04-01

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Effective date: 19941013