ES2037608A1 - Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol". - Google Patents

Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol".

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Publication number
ES2037608A1
ES2037608A1 ES919102693A ES9102693A ES2037608A1 ES 2037608 A1 ES2037608 A1 ES 2037608A1 ES 919102693 A ES919102693 A ES 919102693A ES 9102693 A ES9102693 A ES 9102693A ES 2037608 A1 ES2037608 A1 ES 2037608A1
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Spain
Prior art keywords
methyl
prepn
benzimidazole
new
deriv
Prior art date
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Granted
Application number
ES919102693A
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English (en)
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ES2037608B1 (es
Inventor
Bernardo Julio Martin Alvarez
Amuriza Maria Victoria Montes
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TECHQUIN ETABLISSMENT
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TECHQUIN ETABLISSMENT
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Priority to ES9102693A priority Critical patent/ES2037608B1/es
Publication of ES2037608A1 publication Critical patent/ES2037608A1/es
Application granted granted Critical
Publication of ES2037608B1 publication Critical patent/ES2037608B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL 2-[[[3-METIL-4-2(2,2,2-TRIFLUOROETOXI)-2-PIRIDINIL]-METIL]SULFINIL]-1H-BENZIMIDAZOL. EL PROCEDIMIENTO CONSISTE EN UNA SUSTITUCION NUCLEOFILA CON 2,2,2-TRIFLUOROETANOL SOBRE EL 2-[[[3-METIL-4-NITRO-2-PIRIDINIL]-METIL]SULFINIL]-1H-BENZIMIDAZOL EN MEDIO BASICO Y AISLAR EL PRODUCTO DESEADO POR LOS METODOS CONVENCIONALES, PARA FORMAR POTESTATIVAMENTE SUS SALES, DESARROLLANDOSE EL PROCESO DE ACUERDO CON EL SIGUIENTE ESQUEMA DE REACCION A UNA TEMPERATURA ENTRE 0GC Y LA DE REFLUJO DEL DISOLVENTE.
ES9102693A 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol". Expired - Lifetime ES2037608B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9102693A ES2037608B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9102693A ES2037608B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol".

Publications (2)

Publication Number Publication Date
ES2037608A1 true ES2037608A1 (es) 1993-06-16
ES2037608B1 ES2037608B1 (es) 1994-04-01

Family

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Family Applications (1)

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ES9102693A Expired - Lifetime ES2037608B1 (es) 1991-12-02 1991-12-02 Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol".

Country Status (1)

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ES (1) ES2037608B1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004109A1 (en) * 1999-07-14 2001-01-18 Quimica Sintetica, S.A. Process for the production of 2-(2-pyridinylmethylsulphinyl)-1h-benzimidazoles
ES2187248A1 (es) * 2000-08-25 2003-05-16 Sint Quimica Sa Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174988A (en) * 1983-02-11 1986-11-19 Haessle Ab Intermediates for pyridyl alkylthio-benzimidazole derivatives
ES2020494A6 (es) * 1990-07-25 1991-08-01 Union Quimico Farmaceutica, S.A. Procedimiento para obtener omeprazol.
ES2023609A6 (es) * 1990-11-29 1992-01-16 Inke Sa Procedimiento para la obtencion del 2-(((3-metil -4-(2,2,2-trifluoroetoxi) -2-piridinil) metilisulfinil) -1h-bemzimidazol.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174988A (en) * 1983-02-11 1986-11-19 Haessle Ab Intermediates for pyridyl alkylthio-benzimidazole derivatives
ES2020494A6 (es) * 1990-07-25 1991-08-01 Union Quimico Farmaceutica, S.A. Procedimiento para obtener omeprazol.
ES2023609A6 (es) * 1990-11-29 1992-01-16 Inke Sa Procedimiento para la obtencion del 2-(((3-metil -4-(2,2,2-trifluoroetoxi) -2-piridinil) metilisulfinil) -1h-bemzimidazol.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004109A1 (en) * 1999-07-14 2001-01-18 Quimica Sintetica, S.A. Process for the production of 2-(2-pyridinylmethylsulphinyl)-1h-benzimidazoles
ES2187248A1 (es) * 2000-08-25 2003-05-16 Sint Quimica Sa Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol.

Also Published As

Publication number Publication date
ES2037608B1 (es) 1994-04-01

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Effective date: 19941013