ES2037401T3 - Procedimiento para preparar derivados de nucleosidos. - Google Patents

Procedimiento para preparar derivados de nucleosidos.

Info

Publication number
ES2037401T3
ES2037401T3 ES198989202509T ES89202509T ES2037401T3 ES 2037401 T3 ES2037401 T3 ES 2037401T3 ES 198989202509 T ES198989202509 T ES 198989202509T ES 89202509 T ES89202509 T ES 89202509T ES 2037401 T3 ES2037401 T3 ES 2037401T3
Authority
ES
Spain
Prior art keywords
procedure
nucleoside derivatives
group
preparing nucleoside
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989202509T
Other languages
English (en)
Inventor
Jo Klaveness
Frode Rise
Kjell Undheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed AS filed Critical Nycomed AS
Application granted granted Critical
Publication of ES2037401T3 publication Critical patent/ES2037401T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPONENTES DE LA FORMULA (I) EN DONDE Y1 ES UN HIDROGENO O UN ACIL O UN GRUPO ACILOXIMETIL; Z ES UN HIDROGENO O UN GRUPO AZIDO; Y X ES PURINE O UNA BASE PIRIMIDINE O UN ESTER, AMIDA O DERIVADO ACILOXIALQUIL DE ELLO; CON LA PREVISION DE QUE LA MOLECULA CONTENGA AL MENOS UN GRUPO PIRIDINECARBONIL-3-ALQUIL-1-DIHIDRO-1,4. LOS COMPONENTES TIENEN ACTIVIDAD ANTIVIRAL.
ES198989202509T 1988-10-05 1989-10-05 Procedimiento para preparar derivados de nucleosidos. Expired - Lifetime ES2037401T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888823319A GB8823319D0 (en) 1988-10-05 1988-10-05 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2037401T3 true ES2037401T3 (es) 1993-06-16

Family

ID=10644726

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989202509T Expired - Lifetime ES2037401T3 (es) 1988-10-05 1989-10-05 Procedimiento para preparar derivados de nucleosidos.

Country Status (11)

Country Link
EP (2) EP0437527A1 (es)
JP (1) JPH04500809A (es)
AT (1) ATE75749T1 (es)
AU (1) AU626600B2 (es)
DE (1) DE68901443D1 (es)
ES (1) ES2037401T3 (es)
GB (1) GB8823319D0 (es)
GR (1) GR3004905T3 (es)
NZ (1) NZ230920A (es)
WO (1) WO1990004603A1 (es)
ZA (1) ZA897593B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
JPH05501404A (ja) * 1989-11-06 1993-03-18 ニユコメド・アクシエセルカペト ヌクレオシド誘導体
AU7558491A (en) * 1990-04-04 1991-10-30 Nycomed Imaging As Nucleoside derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8704298D0 (sv) * 1987-11-03 1987-11-03 Astra Ab Compounds for use in therapy
AU610344B2 (en) * 1988-02-29 1991-05-16 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds

Also Published As

Publication number Publication date
EP0437527A1 (en) 1991-07-24
AU626600B2 (en) 1992-08-06
GR3004905T3 (es) 1993-04-28
EP0366171B1 (en) 1992-05-06
AU4425589A (en) 1990-05-14
WO1990004603A1 (en) 1990-05-03
ZA897593B (en) 1990-07-25
JPH04500809A (ja) 1992-02-13
GB8823319D0 (en) 1988-11-09
EP0366171A1 (en) 1990-05-02
DE68901443D1 (de) 1992-06-11
NZ230920A (en) 1991-07-26
ATE75749T1 (de) 1992-05-15

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