ES2035205T3 - Aductos de acido boronico de renio e isotopos radiactivos de complejos de renio y dioxima. - Google Patents

Aductos de acido boronico de renio e isotopos radiactivos de complejos de renio y dioxima.

Info

Publication number
ES2035205T3
ES2035205T3 ES198888116515T ES88116515T ES2035205T3 ES 2035205 T3 ES2035205 T3 ES 2035205T3 ES 198888116515 T ES198888116515 T ES 198888116515T ES 88116515 T ES88116515 T ES 88116515T ES 2035205 T3 ES2035205 T3 ES 2035205T3
Authority
ES
Spain
Prior art keywords
renium
dioxyme
radioactive isotopes
complexes
boronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888116515T
Other languages
English (en)
Inventor
Lynn Carol Francesconi
Elizabeth Noah Treher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of ES2035205T3 publication Critical patent/ES2035205T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTA EL ACIDO BORICO COMO DETERMINANTE DE LA ADUCCION DE ISOTOPOS RADIOACTIVOS DE COMPLEJOS DE DIOXIMA DE RENIO QUE ES UTIL PARA ETIQUETAR COMPUESTOS BIOLOGICAMENTE ACTIVOS COMO AGENTES PARA RADIOTERAPIA.
ES198888116515T 1987-10-13 1988-10-06 Aductos de acido boronico de renio e isotopos radiactivos de complejos de renio y dioxima. Expired - Lifetime ES2035205T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/107,209 US4871836A (en) 1987-10-13 1987-10-13 Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes

Publications (1)

Publication Number Publication Date
ES2035205T3 true ES2035205T3 (es) 1993-04-16

Family

ID=22315440

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888116515T Expired - Lifetime ES2035205T3 (es) 1987-10-13 1988-10-06 Aductos de acido boronico de renio e isotopos radiactivos de complejos de renio y dioxima.

Country Status (12)

Country Link
US (1) US4871836A (es)
EP (1) EP0311891B1 (es)
JP (1) JPH01132594A (es)
AT (1) ATE80888T1 (es)
AU (1) AU616207B2 (es)
CA (1) CA1284649C (es)
DE (1) DE3874852T2 (es)
DK (1) DK568788A (es)
ES (1) ES2035205T3 (es)
GR (1) GR3006633T3 (es)
NZ (1) NZ226255A (es)
ZA (1) ZA887113B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5069900A (en) * 1989-08-28 1991-12-03 E. R. Squibb & Sons, Inc. Boronic acid adducts of technetium-99m dioxime-imine complexes
US5118797A (en) * 1989-08-28 1992-06-02 E. R. Squibb & Sons, Inc. Rhenium tris dioxime complexes
CA2034042C (en) 1990-01-18 1999-08-17 Adrian D. Nunn Boronic acid adducts of rhenium dioxime and technetium-99m dioxime complexes containing a biochemically active group
US5183653A (en) * 1990-04-13 1993-02-02 E. R. Squibb & Sons, Inc. Boronic acid adducts of metal dioxime complexes useful in labelling proteins and other amine-containing compounds
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
US5300280A (en) * 1992-02-14 1994-04-05 Mallinckrodt Medical, Inc. Stabilized radiopharmaceutical kits
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
DE69501981T2 (de) 1994-01-12 1998-12-10 Bracco International B.V., Amsterdam Liganden und deren metallkomplexe
IT1289660B1 (it) * 1996-10-03 1998-10-16 Sorin Biomedica Diagnost Spa Procedimento per la riduzione di composti ossigenati del renio o del tecnezio
US6056941A (en) * 1999-07-28 2000-05-02 Bracco Research Usa Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent
US7026415B2 (en) * 2004-02-17 2006-04-11 Equistar Chemicals, Lp Clathrochelates as olefin polymerization catalyst components
JP4843417B2 (ja) * 2006-08-31 2011-12-21 Ｊｕｋｉ株式会社 ボトルホルダ
US8610075B2 (en) 2006-11-13 2013-12-17 Biosensors International Group Ltd. Radioimaging applications of and novel formulations of teboroxime

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387087A (en) * 1980-04-18 1983-06-07 Research Corporation Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4434151A (en) * 1982-11-08 1984-02-28 Medi-Physics, Inc. Bifunctional chelating agents
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4647445A (en) * 1984-03-28 1987-03-03 Massachusetts Institute Of Technology Radiolabelled lipoproteins and method for making same
US4652440A (en) * 1984-05-03 1987-03-24 Paik Chang H Method of stably radiolabeling antibodies with technetium and rhenium
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
US4707544A (en) * 1984-11-28 1987-11-17 President And Fellows Of Harvard College Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents
US4705849A (en) * 1985-04-15 1987-11-10 E. R. Squibb & Sons, Inc. Boronic acid adducts of technetium-99m dioxime complexes
US4680338A (en) * 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
US4714605A (en) * 1986-10-14 1987-12-22 E. R. Squibb & Sons, Inc. Technetium-99m labeled dioxime complexes

Also Published As

Publication number Publication date
JPH01132594A (ja) 1989-05-25
ZA887113B (en) 1989-05-30
DE3874852D1 (de) 1992-10-29
CA1284649C (en) 1991-06-04
DK568788A (da) 1989-04-14
EP0311891A1 (en) 1989-04-19
ATE80888T1 (de) 1992-10-15
DK568788D0 (da) 1988-10-12
AU2288988A (en) 1989-04-13
GR3006633T3 (es) 1993-06-30
NZ226255A (en) 1990-09-26
EP0311891B1 (en) 1992-09-23
AU616207B2 (en) 1991-10-24
DE3874852T2 (de) 1993-04-15
US4871836A (en) 1989-10-03

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