ES2058360T3 - Nuevos derivados del acido alfa-aminodicarboxilico, su obtencion y empleo. - Google Patents

Nuevos derivados del acido alfa-aminodicarboxilico, su obtencion y empleo.

Info

Publication number
ES2058360T3
ES2058360T3 ES89103446T ES89103446T ES2058360T3 ES 2058360 T3 ES2058360 T3 ES 2058360T3 ES 89103446 T ES89103446 T ES 89103446T ES 89103446 T ES89103446 T ES 89103446T ES 2058360 T3 ES2058360 T3 ES 2058360T3
Authority
ES
Spain
Prior art keywords
alpha
obtaining
employment
new derivatives
aminodicarboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89103446T
Other languages
English (en)
Inventor
Joerg Dr Rosenberg
Hans-Heinrich Dr Grunhagen
Dieter Prof Dr Lenke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of ES2058360T3 publication Critical patent/ES2058360T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

SE DESCRIBEN NUEVOS DERIVADOS DEL ACIDO (ALFA)-AMINOCARBOXILICO DE FORMULA I, DONDE N, X, Y Y Z TIENEN LA SIGNIFICACION QUE SE CITA EN LA DESCRIPCION, Y SU OBTENCION. LOS COMPUESTOS SON ADECUADOS COMO MATERIAL PORTADOR.
ES89103446T 1988-03-03 1989-02-28 Nuevos derivados del acido alfa-aminodicarboxilico, su obtencion y empleo. Expired - Lifetime ES2058360T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3806852A DE3806852A1 (de) 1988-03-03 1988-03-03 Neue (alpha)-aminodicarbonsaeure-derivate, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
ES2058360T3 true ES2058360T3 (es) 1994-11-01

Family

ID=6348703

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89103446T Expired - Lifetime ES2058360T3 (es) 1988-03-03 1989-02-28 Nuevos derivados del acido alfa-aminodicarboxilico, su obtencion y empleo.

Country Status (7)

Country Link
US (1) US5370877A (es)
EP (1) EP0331092B1 (es)
JP (1) JP2585785B2 (es)
AT (1) ATE92469T1 (es)
CA (1) CA1333719C (es)
DE (2) DE3806852A1 (es)
ES (1) ES2058360T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4023241A1 (de) * 1990-07-21 1992-01-23 Knoll Ag Stabile wirkstoff-formulierung
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6020373A (en) * 1995-10-20 2000-02-01 Eastern Virginia Medical School Chelate derivatives as protectors against tissue injury
US5994598A (en) * 1998-01-15 1999-11-30 Doyle E. Chastain Method of preparing perillyl alcohol and perillyl acetate
JP4226324B2 (ja) * 2000-11-10 2009-02-18 学校法人早稲田大学 カルボン酸型脂質
JP5093547B2 (ja) * 2001-08-24 2012-12-12 日本ケミカルリサーチ株式会社 両イオン性脂質およびその用途
US20060110438A1 (en) * 2004-11-24 2006-05-25 Makoto Suematsu Liposome stabilizing agent
JP5303269B2 (ja) * 2005-06-06 2013-10-02 学校法人早稲田大学 骨髄指向性薬物送達物質およびその用途
WO2016210190A1 (en) 2015-06-24 2016-12-29 Nitto Denko Corporation Ionizable compounds and compositions and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
US4729989A (en) * 1985-06-28 1988-03-08 Merck & Co., Inc. Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts
JPH0826092B2 (ja) * 1985-12-13 1996-03-13 株式会社トクヤマ 重合体粒子
DE3617824A1 (de) * 1986-05-27 1987-12-03 Hoechst Ag Zusammensetzung fuer transdermale therapeutische systeme von schleifendiuretika

Also Published As

Publication number Publication date
EP0331092A3 (en) 1990-11-07
JP2585785B2 (ja) 1997-02-26
US5370877A (en) 1994-12-06
EP0331092B1 (de) 1993-08-04
CA1333719C (en) 1994-12-27
ATE92469T1 (de) 1993-08-15
EP0331092A2 (de) 1989-09-06
JPH023642A (ja) 1990-01-09
DE3806852A1 (de) 1989-09-14
DE58905079D1 (de) 1993-09-09

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