ES2031357T3 - Metodo de preparar una combinacion antiviral. - Google Patents

Metodo de preparar una combinacion antiviral.

Info

Publication number
ES2031357T3
ES2031357T3 ES198989306468T ES89306468T ES2031357T3 ES 2031357 T3 ES2031357 T3 ES 2031357T3 ES 198989306468 T ES198989306468 T ES 198989306468T ES 89306468 T ES89306468 T ES 89306468T ES 2031357 T3 ES2031357 T3 ES 2031357T3
Authority
ES
Spain
Prior art keywords
preparing
ribonucleotide reductase
viral combination
viral
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989306468T
Other languages
English (en)
Inventor
Todd Andrew Blumenkopf
Thomas Spector
Devron Randolph Averett
Robert William Morrison, Jr.
Eric Cleveland Bigham
Virgil Lee Styles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of ES2031357T3 publication Critical patent/ES2031357T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS INHIBIDORES DE REDUCTASA RIBONUCLEOTIDOS Y A NUEVAS COMBINACIONES, QUE CONSTAN DE UN COMPUESO ANTIVIRAL, TAL COMO ACICLOVIR Y A UN INHIBIDOR DE REDUCTASA RIBONUCLEOTIDO DE TIOCARBOHIDRAZONA PARA EL TRATAMIENTO QUIMIOTERAPEUTICO O PROFILASIS DE INFECCIONES VIRICAS, ESPECIALMENTE VIRUS DEL GRUPO HERPES.
ES198989306468T 1988-06-27 1989-06-26 Metodo de preparar una combinacion antiviral. Expired - Lifetime ES2031357T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888815241A GB8815241D0 (en) 1988-06-27 1988-06-27 Antiviral combinations & compounds therefor

Publications (1)

Publication Number Publication Date
ES2031357T3 true ES2031357T3 (es) 1992-12-01

Family

ID=10639423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989306468T Expired - Lifetime ES2031357T3 (es) 1988-06-27 1989-06-26 Metodo de preparar una combinacion antiviral.

Country Status (19)

Country Link
US (3) US5175165A (es)
EP (1) EP0349243B1 (es)
JP (1) JPH0245423A (es)
KR (1) KR910000149A (es)
AT (1) ATE74276T1 (es)
AU (1) AU626304B2 (es)
DE (1) DE68901111D1 (es)
DK (1) DK315889A (es)
ES (1) ES2031357T3 (es)
FI (1) FI893112A (es)
GB (1) GB8815241D0 (es)
GR (1) GR3005067T3 (es)
HU (1) HU206264B (es)
IE (1) IE64496B1 (es)
IL (1) IL90750A0 (es)
MY (1) MY106304A (es)
NZ (1) NZ229711A (es)
PT (1) PT90972B (es)
ZA (1) ZA894835B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164395A (en) * 1988-06-27 1992-11-17 Burroughs Wellcome Co. Antiviral acetyl pyridine derivative or said acetyl pyridine derivative in combination with acyclovir
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
US5674849A (en) * 1990-10-24 1997-10-07 Allelix Biopharmaceuticals Inc. Anti-viral compositions
CA2033448C (en) * 1990-12-31 1996-11-26 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes compositions and method of use
CA2033447C (en) * 1990-12-31 1999-08-31 Robert Deziel Synergistic combination for treating herpes infections
US5580571A (en) * 1991-10-15 1996-12-03 Hostetler; Karl Y. Nucleoside analogues
US5879700A (en) * 1991-10-15 1999-03-09 Hostetler; Karl Y. Nucleoside analogue phosphates for topical use
AU701574B2 (en) * 1993-05-12 1999-02-04 Karl Y. Hostetler Acyclovir derivatives for topical use
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
US6015573A (en) * 1993-05-12 2000-01-18 Hostetler; Karl Y. Nucleoside phosphate therapy for viral infection
GB9315755D0 (en) * 1993-07-30 1993-09-15 Wellcome Found Stabilized formulation
WO1996001638A1 (en) * 1994-07-11 1996-01-25 Hoechst Marion Roussel, Inc. Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
CA2224008C (en) 1995-06-07 2009-08-18 Trimeris, Inc. The treatment of hiv and other viral infections using combinatorial therapy
US20030212051A1 (en) * 2001-04-06 2003-11-13 Polli James E Bile acid containing prodrugs with enhanced bioavailabilty
EP1750718B1 (en) 2004-05-19 2014-08-13 Emisphere Technologies, Inc. Acyclovir formulations
JP4972062B2 (ja) * 2008-03-17 2012-07-11 メディヴィル・アクチエボラーグ 抗ウイルス製剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4777166A (en) * 1982-03-30 1988-10-11 The United States Of America As Represented By The Secretary Of The Army 2-acetylpyridine thiosemicarbazone compositions as anitviral agents
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
GB8320308D0 (en) * 1983-07-28 1983-09-01 Wellcome Found Antiviral combinations
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
US4829055A (en) * 1987-01-23 1989-05-09 Naficy Sadeque S Method of treatment for herpes infections of external tissues
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
GB8823319D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds

Also Published As

Publication number Publication date
PT90972A (pt) 1989-12-29
IE64496B1 (en) 1995-08-09
AU626304B2 (en) 1992-07-30
US5175165A (en) 1992-12-29
AU3702689A (en) 1990-02-01
JPH0245423A (ja) 1990-02-15
IL90750A0 (en) 1990-01-18
KR910000149A (ko) 1991-01-29
EP0349243A3 (en) 1990-07-11
PT90972B (pt) 1995-01-31
MY106304A (en) 1995-04-29
NZ229711A (en) 1992-08-26
HUT52379A (en) 1990-07-28
IE892060L (en) 1989-12-27
US5021437A (en) 1991-06-04
DK315889D0 (da) 1989-06-26
GB8815241D0 (en) 1988-08-03
DK315889A (da) 1989-12-28
FI893112A0 (fi) 1989-06-26
GR3005067T3 (es) 1993-05-24
EP0349243B1 (en) 1992-04-01
EP0349243A2 (en) 1990-01-03
DE68901111D1 (de) 1992-05-07
FI893112A (fi) 1989-12-28
HU206264B (en) 1992-10-28
US5393883A (en) 1995-02-28
ZA894835B (en) 1991-02-27
ATE74276T1 (de) 1992-04-15

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