ES2027528A6 - Procedimiento para la obtencion de polimeros con actividad antiviral. - Google Patents
Procedimiento para la obtencion de polimeros con actividad antiviral.Info
- Publication number
- ES2027528A6 ES2027528A6 ES9003222A ES9003222A ES2027528A6 ES 2027528 A6 ES2027528 A6 ES 2027528A6 ES 9003222 A ES9003222 A ES 9003222A ES 9003222 A ES9003222 A ES 9003222A ES 2027528 A6 ES2027528 A6 ES 2027528A6
- Authority
- ES
- Spain
- Prior art keywords
- polymers
- groups
- water
- antiviral activity
- sulfonated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920000642 polymer Polymers 0.000 title abstract 5
- 230000000840 anti-viral effect Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229920001542 oligosaccharide Polymers 0.000 abstract 2
- 150000002482 oligosaccharides Polymers 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- -1 aliphatic amino-sulfonates Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000014508 negative regulation of coagulation Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE POLIMEROS CON ACTIVIDAD ANTIVIRAL, QUE SE CARACTERIZA PORQUE A PARTIR DE OLIGO O POLISACARIDOS CON UNA DETERMINADA ESTRUCTURA SE OBTIENEN POR OXIDACION POLIMEROS CON UN DETERMINADO NUMERO DE GRUPOS CARBONILO; PORQUE SE HACEN REACCIONAR EN AGUA O EN MEZCLAS DE AGUA CON SOLVENTES MISCIBLES CON AGUA, EN CONDICIONES DETERMINADAS DE TEMPERATURA, TIEMPO Y PH, LOS GRUPOS CARBONILO DE LOS OLIGO/POLISACARIDOS OXIDADOS CON GRUPOS AMINO DE MOLECULAS PORTADORAS DE GRUPOS DE GRUPO AMINO Y SULFONATO, COMO POR EJEMPLO AMINOSULFONATOS ALIFATICOS, LO QUE DA LUGAR A POLIMEROS PORTADORES DE GRUPOS SULFONATOS, QUE SE PURIFICAN POR PROCEDIMIENTOS HABITUALES. TIENEN APLICACION EN LA INDUSTRIA FARMACEUTICA.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003222A ES2027528A6 (es) | 1990-12-17 | 1990-12-17 | Procedimiento para la obtencion de polimeros con actividad antiviral. |
| US07/806,669 US5252728A (en) | 1990-12-17 | 1991-12-13 | Process for obtaining polymers with antiviral activity |
| EP19910500143 EP0491644A3 (en) | 1990-12-17 | 1991-12-16 | Process for obtaining polymers with antiviral activity |
| JP3333715A JPH05186502A (ja) | 1990-12-17 | 1991-12-17 | 抗ウイルス活性を有する重合体の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003222A ES2027528A6 (es) | 1990-12-17 | 1990-12-17 | Procedimiento para la obtencion de polimeros con actividad antiviral. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2027528A6 true ES2027528A6 (es) | 1992-06-01 |
Family
ID=8270087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9003222A Expired - Lifetime ES2027528A6 (es) | 1990-12-17 | 1990-12-17 | Procedimiento para la obtencion de polimeros con actividad antiviral. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5252728A (es) |
| EP (1) | EP0491644A3 (es) |
| JP (1) | JPH05186502A (es) |
| ES (1) | ES2027528A6 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6300057B1 (en) | 1997-02-06 | 2001-10-09 | Large Scale Biology Corporation | Melanins with improved ability to inhibit HIV replication |
| US20030181416A1 (en) * | 2002-01-10 | 2003-09-25 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| US20040009953A1 (en) * | 2002-01-10 | 2004-01-15 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| WO2005004882A1 (en) * | 2003-07-09 | 2005-01-20 | Monash University | Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1013902A (en) * | 1961-05-24 | 1965-12-22 | Hoechst Ag | Process for the preparation of polysaccharides |
| US3856775A (en) * | 1969-07-14 | 1974-12-24 | Ajinomoto Kk | {62 -(1{43 3)-glucans |
| US3660377A (en) * | 1969-10-10 | 1972-05-02 | Cpc International Inc | Production of resins from reducing sugars |
| DE2223618A1 (de) * | 1971-06-14 | 1973-01-04 | Akad Wissenschaften Ddr | Verfahren zur herstellung von in wasser loeslichen kupplungsprodukten aminogruppenhaltiger biologisch-aktiver verbindungen mit carbonylgruppenhaltigen polymeren |
| US4152170A (en) * | 1975-06-18 | 1979-05-01 | Sumitomo Chemical Company, Ltd. | Cross-linked pullulan |
| US4739046A (en) * | 1985-08-19 | 1988-04-19 | Luzio Nicholas R Di | Soluble phosphorylated glucan |
| EP0240098A3 (en) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo and polysaccharides for the treatment of diseases caused by retroviruses |
-
1990
- 1990-12-17 ES ES9003222A patent/ES2027528A6/es not_active Expired - Lifetime
-
1991
- 1991-12-13 US US07/806,669 patent/US5252728A/en not_active Expired - Fee Related
- 1991-12-16 EP EP19910500143 patent/EP0491644A3/en not_active Withdrawn
- 1991-12-17 JP JP3333715A patent/JPH05186502A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05186502A (ja) | 1993-07-27 |
| EP0491644A3 (en) | 1993-06-02 |
| US5252728A (en) | 1993-10-12 |
| EP0491644A2 (en) | 1992-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted |
Owner name: INDUSTRIAL FARMACEUTICA CANTABRIA, S.A. |