ES2007341A6 - Un procedimiento para producir m-csf - Google Patents

Un procedimiento para producir m-csf

Info

Publication number
ES2007341A6
ES2007341A6 ES878701345A ES8701345A ES2007341A6 ES 2007341 A6 ES2007341 A6 ES 2007341A6 ES 878701345 A ES878701345 A ES 878701345A ES 8701345 A ES8701345 A ES 8701345A ES 2007341 A6 ES2007341 A6 ES 2007341A6
Authority
ES
Spain
Prior art keywords
csf
production
deficiencies
protein
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES878701345A
Other languages
English (en)
Inventor
Steven C Clark
Gordon G Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/860,377 external-priority patent/US4879227A/en
Priority claimed from US06/940,362 external-priority patent/US4868119A/en
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Publication of ES2007341A6 publication Critical patent/ES2007341A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN PROCEDIMIENTO PARA PRODUCIR M-CSF (FACTOR ESTIMULANTE DE COLONIAS DE MACROFAGOS).COMPRENDE: CULTIVAR UNA CELULA ADECUADA TRANSFORMADA CON UNA SECUENCIA DE CDNA QUE CODIFICA UNA PROTEINA QUE CONTIENE LA SIGUIENTE SECUENCIA DE AMINOACIDOS:ESTANDO DICHA SECUENCIA EN ASOCIACION OPERATIVA CON UNA SECUENCIA DE CONTROL DE EXPRESION PARA ESTA.TIENE UTILIDAD PARA EL TRATAMIENTO TERAPEUTICO DE LOS TRASTORNOS CARACTERIZADOS POR DEFICIENCIAS EN LAS CELULAS HEMATOPOYETICAS.
ES878701345A 1986-05-06 1987-05-05 Un procedimiento para producir m-csf Expired ES2007341A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/860,377 US4879227A (en) 1986-05-06 1986-05-06 Production of a recombinant human colony stimulating factor
US06/940,362 US4868119A (en) 1986-12-11 1986-12-11 Hematopoietic growth factors

Publications (1)

Publication Number Publication Date
ES2007341A6 true ES2007341A6 (es) 1989-06-16

Family

ID=27127565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES878701345A Expired ES2007341A6 (es) 1986-05-06 1987-05-05 Un procedimiento para producir m-csf

Country Status (21)

Country Link
US (1) US5573763A (es)
EP (1) EP0307402B1 (es)
JP (2) JP2579981B2 (es)
KR (1) KR960004453B1 (es)
AT (1) ATE92966T1 (es)
AU (1) AU606056B2 (es)
CA (1) CA1334942C (es)
DE (1) DE3787020T2 (es)
DK (1) DK2688A (es)
ES (1) ES2007341A6 (es)
FI (1) FI884877A0 (es)
GR (1) GR870688B (es)
HU (1) HU212277B (es)
IE (1) IE60835B1 (es)
IL (1) IL82400A0 (es)
MX (1) MX9203130A (es)
MY (1) MY101209A (es)
NO (1) NO880022L (es)
OA (1) OA09112A (es)
PH (1) PH24301A (es)
WO (1) WO1987006954A1 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
US6146851A (en) * 1985-02-05 2000-11-14 Chiron Corporation DNA encoding NV2 (long form) and carboxy truncated fragments thereof
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
US4808611A (en) * 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトｍ−ｃｓｆ
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
JPH07100720B2 (ja) * 1987-07-17 1995-11-01 森永乳業株式会社 コロニー刺激因子の製造法
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
CA1339757C (en) 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
ATE213950T1 (de) * 1987-09-22 2002-03-15 Chiron Corp Verwendung von rekombinantem koloniestimulierendem faktor-1 zur herstellung eines medikaments gegen cytomegalovirusinfektionen
US5260421A (en) * 1987-12-21 1993-11-09 Applied Research Systems Ars Holding N.V. Site-directed mutagenesis modified glycoprotein hormones
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
AU3578189A (en) * 1988-04-27 1989-11-24 Immunomedics Inc. Improved radiotherapy
US5888495A (en) * 1988-05-23 1999-03-30 Genetics Institute, Inc. Method of producing storage stable M-CSF lyophilizates
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
ATE89737T1 (de) * 1989-01-30 1993-06-15 Schering Corp Behandlung von leukozytstoerungen mit gm-csf.
JP3001969B2 (ja) * 1989-02-10 2000-01-24 カイロン コーポレイション 中和配座エピトープを認識するｍ―ｃｓｆモノクローナル抗体
DE69022606T2 (de) * 1989-02-28 1996-05-02 Morinaga Milk Industry Co Ltd Menschlichen Monozyt-Makrophagen-Koloniestimulierungsfaktor enthaltende Zusammensetzung.
US5288487A (en) * 1989-02-28 1994-02-22 Morinaga Milk Industry Co., Ltd. Human monocyte-macrophage-CSF preparations
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
DE69026440T2 (de) * 1989-07-27 1996-10-17 Denki Kagaku Kogyo Kk Für M-CSF kodierendes Gen und dazu gehörende rekombinante Systeme
AU6125294A (en) * 1993-01-13 1994-08-15 Genetics Institute Inc. Process for producing m-csf 223
EP0907746B1 (en) 1996-04-05 2008-02-20 Novartis Vaccines and Diagnostics, Inc. Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
US6455678B1 (en) * 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
WO1998001151A1 (fr) * 1996-07-10 1998-01-15 Meiji Milk Products Co., Ltd. Nouvelle utilisation de la famille mk comme facteur hematopoietique
EP2266542A3 (en) * 1998-10-01 2013-07-31 Elan Pharma International Limited Controlled release nanoparticulate compositions
US7108852B2 (en) * 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
AR045563A1 (es) * 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
JP2010510219A (ja) * 2006-11-17 2010-04-02 バイオジェン・アイデック・エムエイ・インコーポレイテッド アミロイド関連障害を処置するためのコロニー刺激因子の全身投与
WO2024017998A1 (en) 2022-07-21 2024-01-25 Technische Universität Dresden M-csf for use in the prophylaxis and/or treatment of viral infections in states of immunosuppression
EP4309666A1 (en) 2022-07-21 2024-01-24 Technische Universität Dresden M-csf for use in the prophylaxis and/or treatment of viral infections in states of immunosuppression

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784949A (en) * 1984-04-19 1988-11-15 Cetus Corporation Universal dominant selectable marker cassette
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
ATE80894T1 (de) * 1985-02-05 1992-10-15 Cetus Oncology Corp Reinigung des natuerlichen kolonie-stimulierenden faktors-1.
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
HU215241B (hu) * 1986-10-24 1998-11-30 Cetus Corp. Eljárás telepstimuláló faktor-1 új formáinak előállítására, valamint az eljárásban alkalmazható expressziós kazetta, vektor és rekombináns gazdasejtek előállítására

Also Published As

Publication number Publication date
US5573763A (en) 1996-11-12
IL82400A0 (en) 1987-11-30
KR880701288A (ko) 1988-07-26
JPH01502397A (ja) 1989-08-24
MX9203130A (es) 1992-07-01
GR870688B (en) 1987-09-07
EP0307402B1 (en) 1993-08-11
DK2688D0 (da) 1988-01-05
DE3787020T2 (de) 1993-12-16
EP0307402A1 (en) 1989-03-22
IE870994L (en) 1987-11-06
NO880022D0 (no) 1988-01-05
KR960004453B1 (en) 1996-04-06
DK2688A (da) 1988-03-07
OA09112A (en) 1991-10-31
AU606056B2 (en) 1991-01-31
IE60835B1 (en) 1994-08-24
WO1987006954A1 (en) 1987-11-19
DE3787020D1 (de) 1993-09-16
NO880022L (no) 1988-01-05
HU212277B (en) 1996-04-29
CA1334942C (en) 1995-03-28
JPH07147989A (ja) 1995-06-13
PH24301A (en) 1990-05-29
ATE92966T1 (de) 1993-08-15
EP0307402A4 (en) 1990-02-22
HUT47979A (en) 1989-04-28
FI884877A (fi) 1988-10-21
MY101209A (en) 1991-08-17
AU7289087A (en) 1987-12-01
FI884877A0 (fi) 1988-10-21
JP2579981B2 (ja) 1997-02-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041102