ES2006763A6 - Un metodo para preparar un toxoide inmunogenico. - Google Patents

Un metodo para preparar un toxoide inmunogenico.

Info

Publication number
ES2006763A6
ES2006763A6 ES8701759A ES8701759A ES2006763A6 ES 2006763 A6 ES2006763 A6 ES 2006763A6 ES 8701759 A ES8701759 A ES 8701759A ES 8701759 A ES8701759 A ES 8701759A ES 2006763 A6 ES2006763 A6 ES 2006763A6
Authority
ES
Spain
Prior art keywords
toxoid
preparing
preparing toxoid
toxin
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701759A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2006763A6 publication Critical patent/ES2006763A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/20—Rubella virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN METODO PARA PREPARAR UN TOXOIDE INMUNOGENICO, EN EL QUE SE TRATA UNA TOXINA PROTEINICA, AL MENOS PARCIALMENTE PURIFICADA, CON UN OXIDANTE QUIMICO PARA MODIFICARLA DE MANERA QUE LA TOXINA RESULTE INACTIVADA, PERO MANTENGA SU ACTIVIDAD INMUNOLOGICA, SELECCIONANDOSE EL OXIDANTE ENTRE PEROXIDO DE HIDROGENO, PEROXIDO DE SODIO, CLORAMINA-T, ACIDO PERFOMICO, PEROXIDO DE DIOXANO, ACIDO PERYODICO, PERMANGANATO DE SODIO, HIPOCLORITO DE SODIO Y SUS MEZCLAS, Y, SEGUIDAMENTE, SE RECUPERA LA TOXINA INACTIVADA O PARTES DE LA MISMA. EL TOXOIDE OBTENIDO ES UTIL PARA FORMULAR VACUNAS CONTRA LA TOSFERINA Y OTRAS AFECCIONES.
ES8701759A 1986-06-16 1987-06-15 Un metodo para preparar un toxoide inmunogenico. Expired ES2006763A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/874,637 US4762710A (en) 1986-06-16 1986-06-16 Novel method of preparing toxoid by oxidation and metal ions

Publications (1)

Publication Number Publication Date
ES2006763A6 true ES2006763A6 (es) 1989-05-16

Family

ID=25364220

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701759A Expired ES2006763A6 (es) 1986-06-16 1987-06-15 Un metodo para preparar un toxoide inmunogenico.

Country Status (14)

Country Link
US (1) US4762710A (es)
EP (1) EP0269729B1 (es)
JP (1) JP2617500B2 (es)
KR (1) KR960010834B1 (es)
CN (1) CN1033003C (es)
AT (1) ATE87486T1 (es)
AU (1) AU604497B2 (es)
CA (1) CA1302883C (es)
DE (1) DE3785157T2 (es)
ES (1) ES2006763A6 (es)
GR (1) GR870917B (es)
IL (1) IL82825A (es)
WO (1) WO1987007507A1 (es)
ZA (1) ZA874064B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5165927A (en) * 1986-08-01 1992-11-24 University Of Southern California Composition with modified pertussis toxin
US5032398A (en) * 1986-08-01 1991-07-16 Kaslow Harvey R Selective modification of the catalytic subunit of pertussis toxin
SE455946B (sv) * 1986-10-20 1988-08-22 Trion Forskning & Utveckling Nya pertussistoxin-polypeptider och antigener samt testsatser, vacciner och intradermala hudtestkompositioner
JP2849632B2 (ja) * 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
AU631351B2 (en) * 1988-04-20 1992-11-26 Massachusetts Health Research Institute, Inc. (Mhri) Pertussis toxoid vaccine
AP8900132A0 (en) * 1988-07-22 1991-01-14 Smithkline Biolog Bordetella pertussis vaccine
JP2706792B2 (ja) * 1988-11-29 1998-01-28 財団法人化学及血清療法研究所 百日咳毒素のトキソイド化法
EP0485652A1 (de) * 1990-11-14 1992-05-20 Theurer, Karl E., Prof.Dr.med. Verfahren zur Herstellung von Impfvaccinen gegen Krankheitserreger
US6764682B1 (en) * 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
US6290971B1 (en) 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
EP0834322A3 (en) * 1996-10-04 1998-04-22 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Mycosis vaccine
AU2003239773A1 (en) * 2002-06-28 2004-01-19 Novozymes A/S Preparation of vaccines
US8124397B2 (en) * 2005-08-08 2012-02-28 Oregon Health & Science University Inactivating pathogens with oxidizing agents for vaccine production
WO2021001540A1 (en) 2019-07-04 2021-01-07 Proxi Biotech Aps Detoxification of proteins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097141A (en) * 1959-02-26 1963-07-09 Kidwell Elizabeth N Wilcox Immunological method
US3529057A (en) * 1964-08-14 1970-09-15 Takeda Chemical Industries Ltd Purified periodic acid-oxidized mucopeptide of mycobacteria cell walls constituting a vaccine enhancing nonspecific host resistance against pathogenic bacterial infections
US3825525A (en) * 1969-08-06 1974-07-23 Beecham Group Ltd Allergens reacted with carbodiimides
US4185090A (en) * 1972-02-02 1980-01-22 Abbott Laboratories Chemically modified endotoxin immunizing agent
US4058599A (en) * 1973-02-24 1977-11-15 Bayer Aktiengesellschaft Ethyleneimine inactivated organisms
DE2340911A1 (de) * 1973-08-13 1975-05-07 Behringwerke Ag Tetanus-antigen und verfahren zu seiner herstellung
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
US4172126A (en) * 1976-11-08 1979-10-23 Sankyo Company Limited Method for the inactivation of microbial toxins and attenuation of vaccines
US4256732A (en) * 1978-08-15 1981-03-17 Research Corporation Modified grass pollen antigens
JPS55118420A (en) * 1979-03-07 1980-09-11 Sankyo Co Ltd Preparation of improved vaccine for hooping cough
US4314993A (en) * 1980-04-04 1982-02-09 Smithkline-Rit Immunogenic E. coli ST enterotoxin derivatives and compositions containing them
FR2498192A2 (fr) * 1981-01-22 1982-07-23 Pasteur Institut Nouveau compose polypeptidique thiole provenant d'un fragment de la toxine tetanique, son procede d'obtention et ses applications
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
CH664497A5 (de) * 1984-08-31 1988-03-15 Solco Basel Ag Vakzine zur behandlung der harnwegsinfektionen.

Also Published As

Publication number Publication date
EP0269729A1 (en) 1988-06-08
ZA874064B (en) 1988-04-27
CA1302883C (en) 1992-06-09
EP0269729B1 (en) 1993-03-31
IL82825A0 (en) 1987-12-20
DE3785157T2 (de) 1993-11-04
ATE87486T1 (de) 1993-04-15
DE3785157D1 (de) 1993-05-06
US4762710A (en) 1988-08-09
KR880701109A (ko) 1988-07-25
CN87104279A (zh) 1988-01-20
GR870917B (en) 1987-10-15
CN1033003C (zh) 1996-10-16
KR960010834B1 (ko) 1996-08-09
EP0269729A4 (en) 1988-10-06
WO1987007507A1 (en) 1987-12-17
AU7804787A (en) 1988-01-11
JP2617500B2 (ja) 1997-06-04
JPH01500354A (ja) 1989-02-09
IL82825A (en) 1992-05-25
AU604497B2 (en) 1990-12-20

Similar Documents

Publication Publication Date Title
ES2006763A6 (es) Un metodo para preparar un toxoide inmunogenico.
AU6760987A (en) Method of treating alzheimer's disease
ZA837603B (en) Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine
AU7176087A (en) Vaccine formulation
EP0283505A4 (en) VACCINE AND PRODUCTION METHOD.
JPS5341419A (en) Reducing or inactivatzng method of toxin of microorganism and production of vaccine
EP0162639A3 (en) Antigenic preparations and isolation of such preparations
DE3069433D1 (en) Method for producing pertussis toxoid
EP0202947A3 (en) Vaccine production
ES8602416A1 (es) Procedimiento para preparar extractos de manzanilla ricos enflavona
CA2044721A1 (en) Preparation and use of enzyme-detergent extracted streptococcus zooepidemicus vaccine
AU601415B2 (en) A process for the purification, solubilization and/or detoxification of protein antigens of bacteria of the bordetella genus using a carbonate buffer and an acellular anti-whooping cough vaccine
EP0367302A3 (en) Process for semi-synthesis of human insulin, water-soluble cross-linked achromobacter protease i for use therein and a process for preparing the same
GR3029726T3 (en) Use of a therapeutic compound for the treatment of bronchitis
EP0161511A3 (en) Pseudomonas bacteria, emulsifying composition comprising pseudomonas bacteria and method of producing a composition comprising pseudomonas bacteria
JPS5244357A (en) Manufacturing method for a plastic retainer for a sliding bearing
EP0338566A3 (en) Pertussis toxoid vaccine
EP0209493A3 (en) Prophylaxis and treatment of whooping cough
IL84258A (en) Preparation of a mutant strain of bordetella bronchiseptica and live attenuated vaccine produced therefrom
ZA862478B (es)
EP0317643A4 (en) PROCESS FOR PRODUCING AN OXIDE-BASED SUPERCONDUCTOR.
FI102973B1 (fi) Menetelmä 17-oksosteroidien valmistamiseksi
ZA877785B (en) Iminooxazolidines,process of preparation and method of use
SU1256381A1 (ru) Способ переработки редкоземельного концентрата
IE862645L (en) Method of administering vaccines

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20070616