JPS55118420A - Preparation of improved vaccine for hooping cough - Google Patents
Preparation of improved vaccine for hooping coughInfo
- Publication number
- JPS55118420A JPS55118420A JP2655079A JP2655079A JPS55118420A JP S55118420 A JPS55118420 A JP S55118420A JP 2655079 A JP2655079 A JP 2655079A JP 2655079 A JP2655079 A JP 2655079A JP S55118420 A JPS55118420 A JP S55118420A
- Authority
- JP
- Japan
- Prior art keywords
- vaccine
- tannin
- treated
- hydrogen peroxide
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
PURPOSE: The vaccine for hooping cough is treated with purified tannin from persimmon and then with hydrogen peroxide to remove or inactivate the toxic ingredients participating in the side-effects.
CONSTITUTION: A dispersion of dead cells of Homophilus pertussis in the physiological salt solution and a purified tannin from persimmon or condensed tannin therefrom are mixed to form a precipitate of light-brown cells. The precipitated cells are dispersed in the physiological salt solution or a phosphate buffer solution adjusted to about 7 pH and treated with hydrogen peroxide to give title vaccine. The concentration of hydrogen peroxide is preferably 3W10%. This treatment inhibits or inactivates lymphocytosis accelerating factor and histamine sensitizing factor without any adverse effect on immunogen. The resulting vaccine is better than conventional vaccine and vaccine treated with purified-tannin in irritating properties.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2655079A JPS55118420A (en) | 1979-03-07 | 1979-03-07 | Preparation of improved vaccine for hooping cough |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2655079A JPS55118420A (en) | 1979-03-07 | 1979-03-07 | Preparation of improved vaccine for hooping cough |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55118420A true JPS55118420A (en) | 1980-09-11 |
JPS6140210B2 JPS6140210B2 (en) | 1986-09-08 |
Family
ID=12196618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2655079A Granted JPS55118420A (en) | 1979-03-07 | 1979-03-07 | Preparation of improved vaccine for hooping cough |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55118420A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0269729A1 (en) * | 1986-06-16 | 1988-06-08 | Ronald D Sekura | Method of preparing toxoid. |
WO2008039171A2 (en) * | 2005-08-08 | 2008-04-03 | Oregon Health & Science University | Inactivating pathogens with hydrogen peroxide for vaccine production |
CN104524154A (en) * | 2014-12-29 | 2015-04-22 | 河南天纳图生物科技有限公司 | Compound fermented traditional Chinese medicine for relieving cough and asthma of livestock and poultry and preparation method of compound fermented traditional Chinese medicine |
-
1979
- 1979-03-07 JP JP2655079A patent/JPS55118420A/en active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0269729A1 (en) * | 1986-06-16 | 1988-06-08 | Ronald D Sekura | Method of preparing toxoid. |
WO2008039171A2 (en) * | 2005-08-08 | 2008-04-03 | Oregon Health & Science University | Inactivating pathogens with hydrogen peroxide for vaccine production |
WO2008039171A3 (en) * | 2005-08-08 | 2008-06-12 | Univ Oregon Health & Science | Inactivating pathogens with hydrogen peroxide for vaccine production |
US8124397B2 (en) | 2005-08-08 | 2012-02-28 | Oregon Health & Science University | Inactivating pathogens with oxidizing agents for vaccine production |
US8716000B2 (en) | 2005-08-08 | 2014-05-06 | Oregon Health And Science University | Inactivating pathogens with oxidizing agents for vaccine production |
US10143740B2 (en) | 2005-08-08 | 2018-12-04 | Oregon Health And Science University | Inactivating pathogens with oxidizing agents for vaccine production |
CN104524154A (en) * | 2014-12-29 | 2015-04-22 | 河南天纳图生物科技有限公司 | Compound fermented traditional Chinese medicine for relieving cough and asthma of livestock and poultry and preparation method of compound fermented traditional Chinese medicine |
Also Published As
Publication number | Publication date |
---|---|
JPS6140210B2 (en) | 1986-09-08 |
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