ES2004874A6 - Un metodo de preparacion de secciones de un bloque de tejido multi-especimenes. - Google Patents
Un metodo de preparacion de secciones de un bloque de tejido multi-especimenes.Info
- Publication number
- ES2004874A6 ES2004874A6 ES8700345A ES8700345A ES2004874A6 ES 2004874 A6 ES2004874 A6 ES 2004874A6 ES 8700345 A ES8700345 A ES 8700345A ES 8700345 A ES8700345 A ES 8700345A ES 2004874 A6 ES2004874 A6 ES 2004874A6
- Authority
- ES
- Spain
- Prior art keywords
- tissues
- casing
- tissue
- rods
- sectioned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00673—Slice arrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
- G01N2474/20—Immunohistochemistry assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
- G01N33/04—Dairy products
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
COMPRENDE: DISPONER UNA PLURALIDAD DE DIFERENTES MUESTRAS DE TEJIDO ANTIGENICAMENTE REACTIVO EN FORMA DE BASTONCITOS DE MAYOR LONGITUD QUE ANCHURA, EN RELACION SUSTANCIALMENTE PARALELA, SOBRE UNA LAMINA ENVOLVENTE; ENVOLVER DICHOS BASTONCITOS DE ESPECIMEN EN DICHA LAMINA PARA FORMAR UN ENVOLTORIO DE BASTONCITO DE ESPECIMEN; INCRUSTAR DICHO ENVOLTORIO EN UN MEDIO DE EMPOTRAMIENTO PRODUCIENDO UN BLOQUE DE TEJIDO MULTI-ESPECIMEN; Y REBANAR DICHA BLOQUE PARA FACILITAR UNA PLURALIDAD DE SECCIONES, COMPRENDIENDO, CADA UNA, UNA SECCION TRANSVERSAL DE LOS BASTONCITOS DE ESPECIMEN DE TEJIDOS EN EL ENVOLTORIO DE BASTONCITO DE ESPECIMEN.ESTOS BLOQUES TIENEN APLICACION EN METODOS INMUNOHISTOQUIMICOS PARA LA RESOLUCION DE PROBLEMAS EN LA DIAGNOSIS HISTOPATOLOGICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82877586A | 1986-02-12 | 1986-02-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2004874A6 true ES2004874A6 (es) | 1989-02-16 |
Family
ID=25252716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8700345A Expired ES2004874A6 (es) | 1986-02-12 | 1987-02-11 | Un metodo de preparacion de secciones de un bloque de tejido multi-especimenes. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4820504A (es) |
EP (1) | EP0238190B1 (es) |
JP (1) | JPS63132163A (es) |
KR (1) | KR870008032A (es) |
AT (1) | ATE91788T1 (es) |
AU (1) | AU606329B2 (es) |
CA (1) | CA1295218C (es) |
DE (1) | DE3786572T2 (es) |
DK (1) | DK68787A (es) |
ES (1) | ES2004874A6 (es) |
FI (1) | FI870578A (es) |
IL (1) | IL81529A0 (es) |
NO (1) | NO870535L (es) |
NZ (1) | NZ219237A (es) |
PT (1) | PT84269A (es) |
ZA (1) | ZA87925B (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4914022A (en) * | 1987-10-21 | 1990-04-03 | Amc Cancer Research Center | Method for preparing multiple tissue samples for microscopic investigation and testing |
GB8813628D0 (en) * | 1988-06-09 | 1988-07-13 | Shandon Southern Prod | Immunostaining |
US5002377A (en) * | 1988-07-07 | 1991-03-26 | City Of Hope | Multi-specimen slides for immunohistologic procedures |
US5290706A (en) * | 1992-11-10 | 1994-03-01 | Camiener Gerald W | Visualization system for retrieval, identification, and positioning of biological samples for subsequent microscopic examination |
US5817032A (en) * | 1996-05-14 | 1998-10-06 | Biopath Automation Llc. | Means and method for harvesting and handling tissue samples for biopsy analysis |
US6037186A (en) * | 1997-07-16 | 2000-03-14 | Stimpson; Don | Parallel production of high density arrays |
ATE407353T1 (de) * | 1997-08-20 | 2008-09-15 | Univ Miami | Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben |
AU743176B2 (en) * | 1997-09-11 | 2002-01-17 | Bioventures, Inc. | Method of making high density arrays |
AU744815B2 (en) * | 1997-09-11 | 2002-03-07 | Bioventures, Inc. | Method of making high density arrays |
PT1012564E (pt) * | 1997-09-11 | 2003-08-29 | Bioventures Inc | Metodo de producao de arranjos de alta densidade |
AU743220B2 (en) * | 1997-09-11 | 2002-01-24 | Bioventures, Inc. | Method of making high density arrays |
US20020155495A1 (en) * | 2000-04-17 | 2002-10-24 | Millstein Larry S. | Method for producing arrays and devices relating thereto |
WO1999019711A1 (en) * | 1997-10-16 | 1999-04-22 | Millstein Larry S | Method for producing arrays and devices relating thereto |
EP1066517B1 (en) * | 1998-02-25 | 2006-11-29 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Cellular arrays for rapid molecular profiling |
US6699710B1 (en) * | 1998-02-25 | 2004-03-02 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor tissue microarrays for rapid molecular profiling |
JP4374139B2 (ja) * | 1998-02-25 | 2009-12-02 | ザ ユナイテッド ステイツ オブ アメリカ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 迅速な分子プロファイリングのための腫瘍組織マイクロアレイ |
EP1674849A3 (en) * | 1998-05-19 | 2006-07-05 | BioVentures, Inc., | Method of making high density arrays |
AU763635B2 (en) * | 1998-10-05 | 2003-07-31 | Biopath Automation, Llc | Apparatus and method for harvesting and handling tissue samples for biopsy analysis |
US20070166834A1 (en) * | 1998-10-05 | 2007-07-19 | Biopath Automation, L.L.C. | Apparatus and method for harvesting and handling tissue samples for biopsy analysis |
US6281004B1 (en) | 1999-04-14 | 2001-08-28 | Cytologix Corporation | Quality control for cytochemical assays |
US7011940B1 (en) * | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
WO2000066259A1 (en) * | 1999-05-05 | 2000-11-09 | Ut-Battelle, Llc | Method and apparatus for combinatorial chemistry |
DE10001136C2 (de) * | 2000-01-13 | 2003-09-04 | Michael Mengel | Verfahren zur Herstellung von Materialblöcken mit multiplen Untersuchungsproben |
JP2004500891A (ja) | 2000-06-22 | 2004-01-15 | クリノミクス バイオサイエンシズ,インク. | 凍結組織マイクロアレイ及びその使用法 |
US20030215936A1 (en) * | 2000-12-13 | 2003-11-20 | Olli Kallioniemi | High-throughput tissue microarray technology and applications |
US20040085443A1 (en) * | 2000-12-13 | 2004-05-06 | Kallioniemi Olli P | Method and system for processing regions of interest for objects comprising biological material |
US6466690C1 (en) * | 2000-12-19 | 2008-11-18 | Bacus Res Lab Inc | Method and apparatus for processing an image of a tissue sample microarray |
US6716619B1 (en) | 2001-02-08 | 2004-04-06 | Clinomics Biosciences, Inc. | Stylet for use with tissue microarrayer and molds |
US6534307B1 (en) | 2001-02-08 | 2003-03-18 | Clinomics Biosciences, Inc. | Frozen tissue microarrayer |
DE10110511C1 (de) * | 2001-02-28 | 2002-10-10 | Attomol Gmbh Molekulare Diagno | Verfahren zur Herstellung eines Arrays zur Detektion von Komponenten aus einer biologischen Probe |
US20030186353A1 (en) * | 2002-04-02 | 2003-10-02 | Page Erickson | Microscopic precision construction of tissue array block |
US20040126837A1 (en) * | 2002-05-23 | 2004-07-01 | Matthew Baker | Pseudo-tissues and uses thereof |
HU2464U (en) * | 2002-06-25 | 2003-03-28 | Szekeres Gyoergy Dr | Hand instrument set for constructing tissue array |
EP1545775B1 (en) * | 2002-09-26 | 2010-06-16 | BioPath Automation, L.L.C. | Cassette and embedding assembly, staging devices, and methods for handling tissue samples |
US7179424B2 (en) * | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
BR0215830A (pt) * | 2002-09-26 | 2005-06-07 | Biopath Automation Llc | Máquinas e métodos automatizados para envolver amostras de tecido nos suportes seccionáveis de micrótomo |
WO2004072268A2 (en) * | 2003-02-12 | 2004-08-26 | Mayo Foundation For Medical Education And Research | Pkhdl1, a homolog of the autosomal recessive kidney disease gene |
KR200327028Y1 (ko) * | 2003-06-17 | 2003-09-19 | 장시창 | 인체조직검사기구 |
WO2005040348A2 (en) * | 2003-10-23 | 2005-05-06 | Georgetown University | Method for two- and three-dimensional microassembly of patterns and structures |
US8012693B2 (en) | 2003-12-16 | 2011-09-06 | 3M Innovative Properties Company | Analysis of chemically crosslinked cellular samples |
MXPA06011020A (es) | 2004-03-24 | 2007-08-14 | Tripath Imaging Inc | Metodos y composiciones para la deteccion de una enfermedad cervical. |
US7854899B2 (en) * | 2004-08-26 | 2010-12-21 | The United States Of America As Represented By The Secretary Of Health And Human Services | Template methods and devices for preparing sample arrays |
US7618809B2 (en) | 2005-03-23 | 2009-11-17 | Gebing Ronald A | Microarrayer with coaxial multiple punches |
ATE548651T1 (de) * | 2005-06-16 | 2012-03-15 | 3M Innovative Properties Co | Verfahren zur klassifizierung chemisch quervernetzter zellulärer proben unter verwendung von massenspektren |
US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
CA2665687C (en) * | 2006-12-12 | 2016-07-05 | Biopath Automation, L.L.C. | Biopsy support with sectionable resilient cellular material |
WO2010007509A1 (en) * | 2008-07-18 | 2010-01-21 | Leica Biosystems Newcastle Limited | Method for preparing cell standard |
WO2010078240A1 (en) * | 2008-12-30 | 2010-07-08 | Biopath Automation, L.L.C. | Systems and methods for processing tissue samples for histopathology |
DK3300667T3 (da) * | 2009-01-22 | 2019-12-02 | Sakura Finetek Usa Inc | Biopsiunderstøtning der kan sektioneres i en mikrotom til orientering af vævsprøver |
GB0908142D0 (en) * | 2009-05-12 | 2009-06-24 | Cancer Res Inst Royal | Sample cutter and production of tissue arrays |
EP2726840B1 (en) | 2011-06-29 | 2020-12-23 | Sorin Musat | Matrix for receiving a tissue sample and use thereof |
DE102012013678A1 (de) | 2012-07-11 | 2014-01-16 | Euroimmun Medizinische Labordiagnostika Ag | Verfahren und Analysevorrichtung zur mikroskopischen Untersuchung eines Gewebeschnittes oder eines Zellausstrichs |
CN103822805A (zh) * | 2012-11-16 | 2014-05-28 | 苏州药明康德新药开发有限公司 | 病理切片展片的方法 |
CN103091151B (zh) * | 2013-01-04 | 2014-10-29 | 复旦大学附属中山医院 | 一种石蜡细胞芯片接种方法 |
CN103241537B (zh) * | 2013-04-24 | 2015-08-05 | 北京优纳科技有限公司 | 切片装载装置 |
CN106442529A (zh) * | 2016-09-26 | 2017-02-22 | 华南农业大学 | 一种新鲜烟叶切片及其制作方法与应用 |
WO2018195353A1 (en) * | 2017-04-20 | 2018-10-25 | Biolyceum, Llc | High-throughput histopathology tool and methods of use |
CN112985938A (zh) * | 2021-02-04 | 2021-06-18 | 山东大学 | 一种纤维超薄切片的制备方法及其应用 |
CN116106108B (zh) * | 2023-02-13 | 2024-04-05 | 杭州瑞普晨创科技有限公司 | 一种细胞蜡块及少量细胞冰冻切片包埋方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2964443A (en) * | 1957-06-25 | 1960-12-13 | Diamond Alkali Co | Method of mounting samples |
DE1919517A1 (de) * | 1968-12-03 | 1970-06-11 | Microbiological Sciences Inc | Mikrobiologisches Gewebezellenpraeparat insbesondere Krebszellenpraeparat und Verfahren zu seiner Herstellung |
CA1232298A (en) * | 1982-03-04 | 1988-02-02 | Abraham Gordon | Sectioning apparatus, section supporting device and method |
ATE33717T1 (de) * | 1983-02-25 | 1988-05-15 | Winfried Dr Med Stoecker | Verfahren und vorrichtungen fuer untersuchungen an unbeweglich gemachtem biologischem material. |
US4569647A (en) * | 1983-09-16 | 1986-02-11 | Pelam, Inc. | Apparatus for preparing and embedding tissue samples for histological examination |
IL74774A (en) * | 1984-04-23 | 1988-05-31 | Abbott Lab | Method for the preparation of immunocytochemical slides with a polylysine solution |
-
1987
- 1987-02-06 US US07/011,689 patent/US4820504A/en not_active Expired - Lifetime
- 1987-02-09 ZA ZA87925A patent/ZA87925B/xx unknown
- 1987-02-10 IL IL81529A patent/IL81529A0/xx unknown
- 1987-02-10 CA CA000529387A patent/CA1295218C/en not_active Expired - Fee Related
- 1987-02-11 DE DE87301163T patent/DE3786572T2/de not_active Expired - Fee Related
- 1987-02-11 NZ NZ219237A patent/NZ219237A/xx unknown
- 1987-02-11 FI FI870578A patent/FI870578A/fi not_active IP Right Cessation
- 1987-02-11 ES ES8700345A patent/ES2004874A6/es not_active Expired
- 1987-02-11 NO NO870535A patent/NO870535L/no unknown
- 1987-02-11 AU AU68697/87A patent/AU606329B2/en not_active Ceased
- 1987-02-11 DK DK068787A patent/DK68787A/da not_active Application Discontinuation
- 1987-02-11 AT AT87301163T patent/ATE91788T1/de not_active IP Right Cessation
- 1987-02-11 EP EP87301163A patent/EP0238190B1/en not_active Expired - Lifetime
- 1987-02-11 PT PT84269A patent/PT84269A/pt unknown
- 1987-02-12 JP JP62030611A patent/JPS63132163A/ja active Pending
- 1987-02-12 KR KR870001169A patent/KR870008032A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE91788T1 (de) | 1993-08-15 |
FI870578A0 (fi) | 1987-02-11 |
NZ219237A (en) | 1990-10-26 |
DK68787A (da) | 1987-08-13 |
JPS63132163A (ja) | 1988-06-04 |
DE3786572T2 (de) | 1993-12-02 |
KR870008032A (ko) | 1987-09-23 |
DK68787D0 (da) | 1987-02-11 |
EP0238190A2 (en) | 1987-09-23 |
PT84269A (en) | 1987-03-01 |
EP0238190A3 (en) | 1989-08-23 |
FI870578A (fi) | 1987-08-13 |
NO870535D0 (no) | 1987-02-11 |
EP0238190B1 (en) | 1993-07-21 |
DE3786572D1 (de) | 1993-08-26 |
US4820504A (en) | 1989-04-11 |
AU606329B2 (en) | 1991-02-07 |
NO870535L (no) | 1987-08-13 |
AU6869787A (en) | 1987-08-13 |
IL81529A0 (en) | 1987-09-16 |
ZA87925B (en) | 1988-01-27 |
CA1295218C (en) | 1992-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19991108 |