DE3786572D1 - Vieltumorige gewebescheiben, verfahren zu deren herstellung und untersuchung der gewebe in solchen scheiben. - Google Patents

Vieltumorige gewebescheiben, verfahren zu deren herstellung und untersuchung der gewebe in solchen scheiben.

Info

Publication number
DE3786572D1
DE3786572D1 DE8787301163T DE3786572T DE3786572D1 DE 3786572 D1 DE3786572 D1 DE 3786572D1 DE 8787301163 T DE8787301163 T DE 8787301163T DE 3786572 T DE3786572 T DE 3786572T DE 3786572 D1 DE3786572 D1 DE 3786572D1
Authority
DE
Germany
Prior art keywords
tissues
casing
discs
examination
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787301163T
Other languages
English (en)
Other versions
DE3786572T2 (de
Inventor
Hector A Battifora
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Research Institute of City of Hope
Original Assignee
Beckman Research Institute of City of Hope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Research Institute of City of Hope filed Critical Beckman Research Institute of City of Hope
Application granted granted Critical
Publication of DE3786572D1 publication Critical patent/DE3786572D1/de
Publication of DE3786572T2 publication Critical patent/DE3786572T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00673—Slice arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G01N33/04—Dairy products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE87301163T 1986-02-12 1987-02-11 Vieltumorige Gewebescheiben, Verfahren zu deren Herstellung und Untersuchung der Gewebe in solchen Scheiben. Expired - Fee Related DE3786572T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82877586A 1986-02-12 1986-02-12

Publications (2)

Publication Number Publication Date
DE3786572D1 true DE3786572D1 (de) 1993-08-26
DE3786572T2 DE3786572T2 (de) 1993-12-02

Family

ID=25252716

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87301163T Expired - Fee Related DE3786572T2 (de) 1986-02-12 1987-02-11 Vieltumorige Gewebescheiben, Verfahren zu deren Herstellung und Untersuchung der Gewebe in solchen Scheiben.

Country Status (16)

Country Link
US (1) US4820504A (de)
EP (1) EP0238190B1 (de)
JP (1) JPS63132163A (de)
KR (1) KR870008032A (de)
AT (1) ATE91788T1 (de)
AU (1) AU606329B2 (de)
CA (1) CA1295218C (de)
DE (1) DE3786572T2 (de)
DK (1) DK68787A (de)
ES (1) ES2004874A6 (de)
FI (1) FI870578A (de)
IL (1) IL81529A0 (de)
NO (1) NO870535L (de)
NZ (1) NZ219237A (de)
PT (1) PT84269A (de)
ZA (1) ZA87925B (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914022A (en) * 1987-10-21 1990-04-03 Amc Cancer Research Center Method for preparing multiple tissue samples for microscopic investigation and testing
GB8813628D0 (en) * 1988-06-09 1988-07-13 Shandon Southern Prod Immunostaining
US5002377A (en) * 1988-07-07 1991-03-26 City Of Hope Multi-specimen slides for immunohistologic procedures
US5290706A (en) * 1992-11-10 1994-03-01 Camiener Gerald W Visualization system for retrieval, identification, and positioning of biological samples for subsequent microscopic examination
US5817032A (en) * 1996-05-14 1998-10-06 Biopath Automation Llc. Means and method for harvesting and handling tissue samples for biopsy analysis
US6037186A (en) * 1997-07-16 2000-03-14 Stimpson; Don Parallel production of high density arrays
CA2301924C (en) * 1997-08-20 2008-12-09 The University Of Miami A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
AU743220B2 (en) * 1997-09-11 2002-01-24 Bioventures, Inc. Method of making high density arrays
AU744815B2 (en) * 1997-09-11 2002-03-07 Bioventures, Inc. Method of making high density arrays
AU743176B2 (en) * 1997-09-11 2002-01-17 Bioventures, Inc. Method of making high density arrays
CN1249418C (zh) * 1997-09-11 2006-04-05 生物风险公司 一种生产目标物质的高密度阵列的方法及高密度阵列
US20020155495A1 (en) * 2000-04-17 2002-10-24 Millstein Larry S. Method for producing arrays and devices relating thereto
CA2306970A1 (en) * 1997-10-16 1999-04-22 Larry S. Millstein Method for producing arrays and devices relating thereto
US6699710B1 (en) * 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
CA2318789C (en) * 1998-02-25 2011-05-10 The United States Of America As Represented By The Secretary Department Of Health And Human Services Cellular arrays for rapid molecular profiling
AU754047B2 (en) * 1998-02-25 2002-10-31 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Tumor tissue microarrays for rapid molecular profiling
EP1674849A3 (de) * 1998-05-19 2006-07-05 BioVentures, Inc., Verfahren zur Herstellung von Arrays hoher Dichte
US20070166834A1 (en) * 1998-10-05 2007-07-19 Biopath Automation, L.L.C. Apparatus and method for harvesting and handling tissue samples for biopsy analysis
DK1146817T3 (en) * 1998-10-05 2017-02-27 Biopath Automation Llc Apparatus and Method for Sampling and Handling Tissue Samples for Biopsy Analysis
US7011940B1 (en) * 1999-04-14 2006-03-14 Medical Discovery Partners Llc Quality control for cytochemical assays
US6281004B1 (en) 1999-04-14 2001-08-28 Cytologix Corporation Quality control for cytochemical assays
AU4698600A (en) * 1999-05-05 2000-11-17 Ut-Battelle, Llc Method and apparatus for combinatorial chemistry
DE10001136C2 (de) * 2000-01-13 2003-09-04 Michael Mengel Verfahren zur Herstellung von Materialblöcken mit multiplen Untersuchungsproben
US8278034B2 (en) 2000-06-22 2012-10-02 Nuclea Biotechnologies, Inc. Methods of making frozen tissue microarrays
US20030215936A1 (en) * 2000-12-13 2003-11-20 Olli Kallioniemi High-throughput tissue microarray technology and applications
US20040085443A1 (en) * 2000-12-13 2004-05-06 Kallioniemi Olli P Method and system for processing regions of interest for objects comprising biological material
US6466690C1 (en) * 2000-12-19 2008-11-18 Bacus Res Lab Inc Method and apparatus for processing an image of a tissue sample microarray
US6716619B1 (en) 2001-02-08 2004-04-06 Clinomics Biosciences, Inc. Stylet for use with tissue microarrayer and molds
US6534307B1 (en) 2001-02-08 2003-03-18 Clinomics Biosciences, Inc. Frozen tissue microarrayer
DE10110511C1 (de) * 2001-02-28 2002-10-10 Attomol Gmbh Molekulare Diagno Verfahren zur Herstellung eines Arrays zur Detektion von Komponenten aus einer biologischen Probe
US20030186353A1 (en) * 2002-04-02 2003-10-02 Page Erickson Microscopic precision construction of tissue array block
AU2003231827A1 (en) * 2002-05-23 2003-12-12 Invitrogen Corporation Pseudo-tissues and uses thereof
HU2464U (en) * 2002-06-25 2003-03-28 Szekeres Gyoergy Dr Hand instrument set for constructing tissue array
CN100518940C (zh) * 2002-09-26 2009-07-29 比欧帕斯自动化公司 操作组织样品的盒子、嵌入组件和方法
US7179424B2 (en) * 2002-09-26 2007-02-20 Biopath Automation, L.L.C. Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
ES2401865T3 (es) * 2002-09-26 2013-04-25 Biopath Automation, L.L.C. Aparato y procedimientos para la manipulación automatizada e incorporación de muestras de tejido
WO2004072268A2 (en) * 2003-02-12 2004-08-26 Mayo Foundation For Medical Education And Research Pkhdl1, a homolog of the autosomal recessive kidney disease gene
KR200327028Y1 (ko) * 2003-06-17 2003-09-19 장시창 인체조직검사기구
WO2005040348A2 (en) * 2003-10-23 2005-05-06 Georgetown University Method for two- and three-dimensional microassembly of patterns and structures
US8012693B2 (en) * 2003-12-16 2011-09-06 3M Innovative Properties Company Analysis of chemically crosslinked cellular samples
KR20080075045A (ko) 2004-03-24 2008-08-13 트리패스 이미징, 인코포레이티드 자궁경부 질환의 검사 방법 및 조성물
US7854899B2 (en) * 2004-08-26 2010-12-21 The United States Of America As Represented By The Secretary Of Health And Human Services Template methods and devices for preparing sample arrays
US7618809B2 (en) 2005-03-23 2009-11-17 Gebing Ronald A Microarrayer with coaxial multiple punches
WO2006138629A2 (en) * 2005-06-16 2006-12-28 3M Innovative Properties Company Method of classifying chemically crosslinked cellular samples using mass spectra
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls
EP2091440B1 (de) * 2006-12-12 2020-04-22 BioPath Automation, L.L.C. Biopsieträger mit auswählbarem elastischem zellmaterial
EP2313754B1 (de) * 2008-07-18 2017-11-01 Leica Biosystems Newcastle Limited Verfahren zur herstellung eines zellstandards
CA2748542A1 (en) * 2008-12-30 2010-07-08 Biopath Automation, L.L.C. Systems and methods for processing tissue samples for histopathology
JP5706341B2 (ja) * 2009-01-22 2015-04-22 バイオパス・オートメーション・エル・エル・シー 組織標本を位置付けするためのミクロトーム薄片化生検支持体
GB0908142D0 (en) * 2009-05-12 2009-06-24 Cancer Res Inst Royal Sample cutter and production of tissue arrays
EP2726840B1 (de) 2011-06-29 2020-12-23 Sorin Musat Matrix zur aufnahme von gewebeproben und dessen verwendung
DE102012013678A1 (de) 2012-07-11 2014-01-16 Euroimmun Medizinische Labordiagnostika Ag Verfahren und Analysevorrichtung zur mikroskopischen Untersuchung eines Gewebeschnittes oder eines Zellausstrichs
CN103822805A (zh) * 2012-11-16 2014-05-28 苏州药明康德新药开发有限公司 病理切片展片的方法
CN103091151B (zh) * 2013-01-04 2014-10-29 复旦大学附属中山医院 一种石蜡细胞芯片接种方法
CN103241537B (zh) * 2013-04-24 2015-08-05 北京优纳科技有限公司 切片装载装置
CN106442529A (zh) * 2016-09-26 2017-02-22 华南农业大学 一种新鲜烟叶切片及其制作方法与应用
WO2018195353A1 (en) * 2017-04-20 2018-10-25 Biolyceum, Llc High-throughput histopathology tool and methods of use
CN112985938A (zh) * 2021-02-04 2021-06-18 山东大学 一种纤维超薄切片的制备方法及其应用
CN116106108B (zh) * 2023-02-13 2024-04-05 杭州瑞普晨创科技有限公司 一种细胞蜡块及少量细胞冰冻切片包埋方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2964443A (en) * 1957-06-25 1960-12-13 Diamond Alkali Co Method of mounting samples
DE1919517A1 (de) * 1968-12-03 1970-06-11 Microbiological Sciences Inc Mikrobiologisches Gewebezellenpraeparat insbesondere Krebszellenpraeparat und Verfahren zu seiner Herstellung
CA1232298A (en) * 1982-03-04 1988-02-02 Abraham Gordon Sectioning apparatus, section supporting device and method
EP0117262B1 (de) * 1983-02-25 1988-04-20 Winfried Dr. med. Stöcker Verfahren und Vorrichtungen für Untersuchungen an unbeweglich gemachtem biologischem Material
US4569647A (en) * 1983-09-16 1986-02-11 Pelam, Inc. Apparatus for preparing and embedding tissue samples for histological examination
IL74774A (en) * 1984-04-23 1988-05-31 Abbott Lab Method for the preparation of immunocytochemical slides with a polylysine solution

Also Published As

Publication number Publication date
AU6869787A (en) 1987-08-13
DK68787D0 (da) 1987-02-11
IL81529A0 (en) 1987-09-16
NZ219237A (en) 1990-10-26
AU606329B2 (en) 1991-02-07
NO870535L (no) 1987-08-13
DK68787A (da) 1987-08-13
KR870008032A (ko) 1987-09-23
FI870578A (fi) 1987-08-13
ZA87925B (en) 1988-01-27
CA1295218C (en) 1992-02-04
NO870535D0 (no) 1987-02-11
ATE91788T1 (de) 1993-08-15
PT84269A (en) 1987-03-01
JPS63132163A (ja) 1988-06-04
EP0238190B1 (de) 1993-07-21
US4820504A (en) 1989-04-11
ES2004874A6 (es) 1989-02-16
EP0238190A2 (de) 1987-09-23
DE3786572T2 (de) 1993-12-02
EP0238190A3 (en) 1989-08-23
FI870578A0 (fi) 1987-02-11

Similar Documents

Publication Publication Date Title
DE3786572D1 (de) Vieltumorige gewebescheiben, verfahren zu deren herstellung und untersuchung der gewebe in solchen scheiben.
JPS52143885A (en) Testing instrument and method of blood hemoglobin
IT8026850A0 (it) Processo per la preparazione di cellulosa in microfibrille e cellulosa ottenuta con lo stesso.
IT1218719B (it) Metodo per la preparazione di suture chirurgiche composite e suture preparate con tale metodo
DE3866544D1 (de) Verfahren zur herstellung multilamellarer vesikel mit grossem waessrigem volumen.
NL7511844A (nl) Werkwijze voor het bereiden van een verdunnings- middel voor bloedmonsters en werkwijze voor het onderzoeken van bloedmonsters.
IT7827793A0 (it) Fenossi-piridinil(pirimidinil)-alca noli, procedimento per la loro preparazione e anche loro impiegocome fungicidi.
MX161464A (es) Procedimiento para preparar biopolimeros celulosicos y hemicelulosicos
ATE3866T1 (de) Verfahren zur herstellung einer kollagenloesung, eine solche loesung sowie ihre verwendung.
IT1083729B (it) Procedimento per il trattamento di eritrociti per la preparazione di materiali di saggio e prodotto ottenuto
NL186918C (nl) Werkwijze ter bereiding van caseine bevattende mengvezels uit eiwit en aldus verkregen vezels.
IT1144738B (it) Procedimento per la preparazione di metafenilendiammine composizioni di tintura che le contengono e procedimento per la tintura dei capelli mediante tali composizioni
AR221127A1 (es) Composicion para tratar fibras proteinicas y metodo para su preparacion
Malor et al. Innervation of the blood vessels in guinea-pig atria
DE3574974D1 (de) Verfahren zur herstellung von milbemycinderivaten und einige in diesem verfahren verwendete derivate.
SU605608A1 (ru) Способ исследовани ветвей магистральных кровеносных сосудов
AT349831B (de) Fungizides, insbesondere systemisch wirkendes mittel und verfahren zur herstellung desselben
SU507274A1 (ru) Устройство дл корчевки пней
AT382312B (de) Verfahren zur herstellung von stabilen pharmazeutischen praeparaten mit antiseptischer underhoehter entzuendungshemmender wirkung zur lokalen anwendung
IT1148270B (it) Poli(alogenoalchileneteri)e procedimento e catalizzatore per la loro preparazione
JPS5352628A (en) Method of treating alcohol poisoning disease and method of removing and preventing thereof
IT7912474A0 (it) Metodo per la decomposizione di polissacaridi in particolare per la trasformazione della cellulosa in glucosio
JPS55130674A (en) Method of inspecting nonnsteady performance of blood dialyzer
PL211286A1 (pl) Sposob preparowania,zwlaszcza klejenia nici oraz urzadzenie do preparowania,zwlaszcza klejenia nici
IT7849601A0 (it) Dispositivo per frazionare sangue in modo continuo e relativo procedimento

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee