ES2002384A6 - Un procedimiento para la preparacion de una base para supositorios - Google Patents

Un procedimiento para la preparacion de una base para supositorios

Info

Publication number
ES2002384A6
ES2002384A6 ES8602273A ES8602273A ES2002384A6 ES 2002384 A6 ES2002384 A6 ES 2002384A6 ES 8602273 A ES8602273 A ES 8602273A ES 8602273 A ES8602273 A ES 8602273A ES 2002384 A6 ES2002384 A6 ES 2002384A6
Authority
ES
Spain
Prior art keywords
percent
carbon atoms
weight
fatty acids
suppository
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8602273A
Other languages
English (en)
Inventor
Yukitaka Tanaka
Minoru Nakamura
Joshin Okada
Kenji Mansho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kao Corp
Original Assignee
Kao Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kao Corp filed Critical Kao Corp
Publication of ES2002384A6 publication Critical patent/ES2002384A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA BASE PARA SUPOSITORIOS. COMPRENDE: A) SOMETER A ENDURECIMIENTO, FRACCIONAMIENTO, TRANESTERIFICACION O DESTILACION UN ACEITE CRUDO PARA DAR UNA GRASA DE TIPO LAURICO CON UN INDICE DE HIDROXILO DE 20 O MENOS Y QUE CONTIENE GLICERIDOS DE ACIDOS GRASOS DE 8 A 18 ATOMOS DE CARBONO; B) AGREGAR GLICEROL A UN ACEITE VEGETAL PARA PRODUCIR UNA TRANSESTERIFICACION ALEATORIA EN PRESENCIA DE UN CATALIZADOR; SOMETER EL PRODUCTO A DESTILACION, CROMATOGRAFIA O FRACCIONAMIENTO PARA DAR UN DIGLICERIDO DE ACIDO GRASO DE 14 A 22 ATOMOS DE CARBONO; Y C) MEZCLAR 80-99% EN PESO DEL PRODUCTO DE (A) CON 1-20% EN PESO DEL PRODUCTO DE (B). LA BASE ES UTIL PARA PREPARAR SUPOSITORIOS DE GRAN MOLDEABILIDAD Y MANEJABILIDAD, CON EXCELENTES CARACTERISTICAS DE SOLIDIFICACION DURANTE EL MOLDEO Y SIN DEFECTOS DEL TIPO DE POROS O GRIETAS.
ES8602273A 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una base para supositorios Expired ES2002384A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21752785 1985-09-30

Publications (1)

Publication Number Publication Date
ES2002384A6 true ES2002384A6 (es) 1988-08-01

Family

ID=16705639

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8602273A Expired ES2002384A6 (es) 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una base para supositorios

Country Status (6)

Country Link
US (1) US4837214A (es)
EP (1) EP0218446B1 (es)
JP (1) JPH0676314B2 (es)
DE (1) DE3679764D1 (es)
ES (1) ES2002384A6 (es)
HK (1) HK17493A (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87390A1 (fr) * 1988-11-17 1990-06-12 Oreal Utilisation du nicotinate d'alpha-tocopherol et/ou du nicotinate d'hexyle dans une composition cosmetique a action amincissante
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
JP3040359U (ja) * 1996-05-21 1997-08-19 幸栄 葛西 ファスナー付き肌着
AU8803901A (en) * 2000-09-21 2002-04-02 Taisho Pharmaceutical Co Ltd Suppositories sustained in the lower rectum
US6462083B1 (en) 2001-11-13 2002-10-08 Sarfaraz K. Niazi Suppository base
DK2368554T3 (en) 2003-04-08 2015-01-26 Progenics Pharm Inc A pharmaceutical composition comprising methylnaltrexone
SE0400233D0 (sv) * 2004-02-04 2004-02-04 Ltp Lipid Technologies Provide Rektal komposition
JP2005314241A (ja) * 2004-04-27 2005-11-10 Tendou Seiyaku Kk ヒビ・ワレの発生が抑制された坐剤基剤及びその製造方法
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
CA2865661C (en) 2007-03-29 2016-05-17 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
CN101801979A (zh) 2007-03-29 2010-08-11 普罗热尼奇制药公司 (r)-n-溴化甲基纳曲酮的晶体形式及其用途
SI2565195T1 (sl) 2007-03-29 2015-09-30 Wyeth Llc Periferalni opioidni receptorji in antagonisti in njih uporaba
JP5358587B2 (ja) 2008-02-06 2013-12-04 プロジェニックス・ファーマシューティカルス・インコーポレイテッド （ｒ），（ｒ）−２，２’−ビス−メチルナルトレキソンの製造及び用途
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
AU2017247008B2 (en) * 2016-04-06 2022-04-07 Noxopharm Limited Isoflavonoid composition with improved pharmacokinetics
CN108178830A (zh) * 2018-01-03 2018-06-19 辽宁奥克医药辅料股份有限公司 一种硬脂酸聚烃氧（40）酯的制备方法
AU2021247415A1 (en) 2020-03-30 2022-09-29 Noxopharm Limited Methods for the treatment of inflammation associated with infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE941014C (de) * 1949-05-19 1956-03-29 Edelfettwerke G M B H Verfahren zur Herstellung von Zaepfchenmassen
DE1015576B (de) * 1953-12-12 1957-09-12 Edelfettwerke Ges Mit Beschrae Verfahren zum Herstellen von Zaepfchenmassen
CA920950A (en) * 1968-07-19 1973-02-13 Hunger Alfred Anti-haemorrhoidally active preparations for rectal administration
DE2243771A1 (de) * 1971-11-23 1973-05-30 Hydrierwerk Rodleben Veb Verfahren zur herstellung von suppositorienmassen
US4406896A (en) * 1979-12-20 1983-09-27 Merck & Co., Inc. Adjuvants for rectal delivery of drug substances
US4698359A (en) * 1982-08-24 1987-10-06 Cilag, Ag Medicated suppository

Also Published As

Publication number Publication date
JPS62174008A (ja) 1987-07-30
DE3679764D1 (de) 1991-07-18
HK17493A (en) 1993-03-12
EP0218446B1 (en) 1991-06-12
JPH0676314B2 (ja) 1994-09-28
EP0218446A3 (en) 1987-08-19
US4837214A (en) 1989-06-06
EP0218446A2 (en) 1987-04-15

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-29