ES2001773A6 - Un procedimiento para preparar un compuesto de cefalosporina - Google Patents

Un procedimiento para preparar un compuesto de cefalosporina

Info

Publication number
ES2001773A6
ES2001773A6 ES8601599A ES8601599A ES2001773A6 ES 2001773 A6 ES2001773 A6 ES 2001773A6 ES 8601599 A ES8601599 A ES 8601599A ES 8601599 A ES8601599 A ES 8601599A ES 2001773 A6 ES2001773 A6 ES 2001773A6
Authority
ES
Spain
Prior art keywords
imidazolium ring
cephalosporin derivatives
cephem
methoxy
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601599A
Other languages
English (en)
Inventor
Kiyotoshi Matsumura
Hiroshi Akagi
Daisuke Suzuki
Akihiro Shimabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61107262A external-priority patent/JPH07107069B2/ja
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of ES2001773A6 publication Critical patent/ES2001773A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LOS COMPUESTOS DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, DONDE R1, R2, R3, A Y B REPRESENTAN UNOS RADICALES Y N ES 0 O 1 SE OBTIENEN POR (A) REACCION DE (II) CON (III) EFECTUADA EN AGUA O EN UN DISOLVENTE ORGANICO, EN PRESENCIA DE UNA BASE O DE OXIDO DE PROPILENO A UNA TEMPERATURA DE -10 A +40 C PARA DAR (IV) EL CUAL, CUANDO ES NECESARIO, SE SOMETE A REDUCCION O A ELIMINACION DEL GRUPO PROTECTOR; O (B) REACCION DE (V) CON (VI) EFECTUADA EN UN DISOLVENTE Y EN PRESENCIA OPCIONAL DE UNA BASE O DE UN AGENTE CONDENSANTE A UNA TEMPERATURA DE -20 A +40 C PARA DAR (IV) EL CUAL, CUANDO ES NECESARIO, SE SOMETE A REDUCCION O A ELIMINACION DEL GRUPO PROTECTOR. LOS COMPUESTOS (I) SON UTILES PARA PREVENIR Y TRATAR INFECCIONES BACTERIANAS.
ES8601599A 1985-09-03 1986-09-03 Un procedimiento para preparar un compuesto de cefalosporina Expired ES2001773A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19438585 1985-09-03
JP61107262A JPH07107069B2 (ja) 1985-09-03 1986-05-10 セフアロスポリン化合物の新規誘導体、その製造法及び該誘導体を含有する医薬組成物

Publications (1)

Publication Number Publication Date
ES2001773A6 true ES2001773A6 (es) 1988-06-16

Family

ID=26447305

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601599A Expired ES2001773A6 (es) 1985-09-03 1986-09-03 Un procedimiento para preparar un compuesto de cefalosporina

Country Status (6)

Country Link
US (1) US4906623A (es)
EP (1) EP0214600B1 (es)
AT (1) ATE82976T1 (es)
CA (1) CA1299564C (es)
DE (1) DE3687200T2 (es)
ES (1) ES2001773A6 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194432A (en) * 1985-11-22 1993-03-16 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
IE63094B1 (en) * 1987-09-14 1995-03-22 Fujisawa Pharmaceutical Co Cephem compound and a process for preparation thereof
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
US5194433A (en) * 1990-11-13 1993-03-16 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
EP2341053B1 (en) * 2008-10-31 2016-01-13 Shionogi&Co., Ltd. Cephalosporin having catechol group
CN102070655B (zh) * 2009-11-23 2012-09-26 山东轩竹医药科技有限公司 含有咪唑环的头孢菌素衍生物
EP2557082A4 (en) 2010-04-05 2013-08-28 Shionogi & Co CEPHEM COMPOUND COMPRISING A CATÉCHOL GROUP
CN102918047A (zh) 2010-04-05 2013-02-06 盐野义制药株式会社 具有假儿茶酚基团的头孢烯类化合物
KR101276121B1 (ko) * 2011-03-11 2013-06-18 대우조선해양 주식회사 이동식 해상 발전 플랜트 및 그 운용 방법
KR101279646B1 (ko) * 2011-12-27 2013-06-26 대우조선해양 주식회사 부유식 해상발전소
AU2021257961A1 (en) * 2020-06-16 2022-01-06 Johnson & Johnson Vision Care, Inc. Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them
US20210388141A1 (en) * 2020-06-16 2021-12-16 Johnson & Johnson Vision Care, Inc. Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5564M (es) * 1964-03-14 1968-01-02
DE2943427A1 (de) * 1978-10-27 1980-05-08 Glaxo Group Ltd Cephalosporinverbindungen
GB2037281B (en) * 1978-11-15 1983-01-19 Glaxo Group Ltd 7( -(2-amino-4-thiozolyl)-2-hydroximino-acetanuds)-cephalosporins
EP0062321B1 (en) * 1981-04-03 1989-03-01 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
JPS584789A (ja) * 1981-04-03 1983-01-11 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
EP0137442A3 (de) * 1983-10-08 1986-01-15 Hoechst Aktiengesellschaft Cephalosporinderivate und Verfahren zu ihrer Herstellung
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
PH22107A (en) * 1984-06-07 1988-06-01 Takeda Chemical Industries Ltd 3-pyrazolo(1,5-a)pyrdinium cephem compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives

Also Published As

Publication number Publication date
ATE82976T1 (de) 1992-12-15
EP0214600A2 (en) 1987-03-18
US4906623A (en) 1990-03-06
CA1299564C (en) 1992-04-28
DE3687200D1 (de) 1993-01-14
EP0214600B1 (en) 1992-12-02
DE3687200T2 (de) 1993-05-27
EP0214600A3 (en) 1988-09-28

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-03