EP4705474A2 - Künstliche tymovirale satelliten rnas - Google Patents

Künstliche tymovirale satelliten rnas

Info

Publication number
EP4705474A2
EP4705474A2 EP24729531.4A EP24729531A EP4705474A2 EP 4705474 A2 EP4705474 A2 EP 4705474A2 EP 24729531 A EP24729531 A EP 24729531A EP 4705474 A2 EP4705474 A2 EP 4705474A2
Authority
EP
European Patent Office
Prior art keywords
rna
virus
hrv
sequence
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24729531.4A
Other languages
English (en)
French (fr)
Inventor
David George BLUMSACK
Fu Chyun CHU
Elizabeth Jane Antonelli DENNIS
Jean-Pierre Baptiste Séhi GLOUZON
Mehmet Ali HALAC
Yumeng HAO
Arjun Devang KHAKHAR
Kevin KLICKI
James Michael KREMER
Jayashree Kumar
Katherine Michelle LATOURRETTE
Barry Andrew Martin
Shankar Raj PANT
Derek Thomas ROTHENHEBER
Michka Gabrielle SHARPE
Aditya Sushil Kumar SINGH
Arjun Subedi
Phu Tri Tran
Paveena VICHYAVICHIEN
Reid Evan William WARSABA
Kaixi ZHAO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flagship Pioneering Innovations VII Inc
Original Assignee
Flagship Pioneering Innovations VII Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flagship Pioneering Innovations VII Inc filed Critical Flagship Pioneering Innovations VII Inc
Publication of EP4705474A2 publication Critical patent/EP4705474A2/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EP24729531.4A 2023-05-03 2024-05-03 Künstliche tymovirale satelliten rnas Pending EP4705474A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363499758P 2023-05-03 2023-05-03
PCT/US2024/027687 WO2024229359A2 (en) 2023-05-03 2024-05-03 Artificial tymovirales satellite rnas

Publications (1)

Publication Number Publication Date
EP4705474A2 true EP4705474A2 (de) 2026-03-11

Family

ID=91302563

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24729531.4A Pending EP4705474A2 (de) 2023-05-03 2024-05-03 Künstliche tymovirale satelliten rnas

Country Status (3)

Country Link
EP (1) EP4705474A2 (de)
AR (1) AR132588A1 (de)
WO (1) WO2024229359A2 (de)

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
ZA859400B (en) 1984-12-10 1986-10-29 Monsanto Co Insertion of the bacillus thuringiensis crystal protein gene into plant-colonizing microorganisms and their use
US6774283B1 (en) 1985-07-29 2004-08-10 Calgene Llc Molecular farming
US6617496B1 (en) 1985-10-16 2003-09-09 Monsanto Company Effecting virus resistance in plants through the use of negative strand RNAs
US6608241B1 (en) 1985-10-29 2003-08-19 Monsanto Technology Llc Protection of plants against viral infection
US5322938A (en) 1987-01-13 1994-06-21 Monsanto Company DNA sequence for enhancing the efficiency of transcription
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US5229114A (en) 1987-08-20 1993-07-20 The United States Of America As Represented By The Secretary Of Agriculture Approaches useful for the control of root nodulation of leguminous plants
US5597718A (en) 1988-10-04 1997-01-28 Agracetus Genetically engineering cotton plants for altered fiber
ES2164633T3 (es) 1989-02-24 2002-03-01 Monsanto Technology Llc Genes vegetales sinteticos y procedimiento para su preparacion.
US5689041A (en) 1989-08-10 1997-11-18 Plant Gentic Systems N.V. Plants modified with barstar for fertility restoration
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
US6426447B1 (en) 1990-11-14 2002-07-30 Monsanto Technology Llc Plant seed oils
US5543576A (en) 1990-03-23 1996-08-06 Mogen International Production of enzymes in seeds and their use
US5969214A (en) 1990-06-11 1999-10-19 Calgene, Inc. Glycogen biosynthetic enzymes in plants
DE69132916T2 (de) 1990-06-18 2002-10-31 Monsanto Technology Llc, St. Louis Erhöhter stärkegehalt in pflanzen
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
ATE213774T1 (de) 1990-06-25 2002-03-15 Monsanto Technology Llc Glyphosattolerante pflanzen
USRE38446E1 (en) 1990-07-20 2004-02-24 Calgene, Llc. Sucrose phosphate synthase (SPS), its process for preparation its cDNA, and utilization of cDNA to modify the expression of SPS in plant cells
US6483008B1 (en) 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
US5866775A (en) 1990-09-28 1999-02-02 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases
FI932960A7 (fi) 1990-12-26 1993-06-24 Monsanto Co Hedelmien kypsymisen ja kasvien vanhenemisen kontrollointi
US5304730A (en) 1991-09-03 1994-04-19 Monsanto Company Virus resistant plants and method therefore
US5763245A (en) 1991-09-23 1998-06-09 Monsanto Company Method of controlling insects
US6015940A (en) 1992-04-07 2000-01-18 Monsanto Company Virus resistant potato plants
US5850023A (en) 1992-11-30 1998-12-15 Monsanto Company Modified plant viral replicase genes
US6011199A (en) 1992-12-15 2000-01-04 Commonwealth Scientific Method for producing fruiting plants with improved fruit flavour
US6013864A (en) 1993-02-03 2000-01-11 Monsanto Company Plants resistant to infection by luteoviruses
US5322687A (en) 1993-07-29 1994-06-21 Ecogen Inc. Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
EP0670670A4 (de) 1993-09-30 1996-04-24 Agracetus Heterologes peroxidase prozuzierende transgene baumwollpflanzen.
HUT74393A (en) 1993-11-24 1996-12-30 Monsanto Co Method of controlling plant pathogens
US5689052A (en) 1993-12-22 1997-11-18 Monsanto Company Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof
US6828475B1 (en) 1994-06-23 2004-12-07 Calgene Llc Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism
US6080560A (en) 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
US6140075A (en) 1994-07-25 2000-10-31 Monsanto Company Method for producing antibodies and protein toxins in plant cells
US5750876A (en) 1994-07-28 1998-05-12 Monsanto Company Isoamylase gene, compositions containing it, and methods of using isoamylases
US5716837A (en) 1995-02-10 1998-02-10 Monsanto Company Expression of sucrose phosphorylase in plants
US6091002A (en) 1996-03-13 2000-07-18 Monsanto Company Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants
US6946588B2 (en) 1996-03-13 2005-09-20 Monsanto Technology Llc Nucleic acid encoding a modified threonine deaminase and methods of use
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US5773696A (en) 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6166292A (en) 1996-04-26 2000-12-26 Ajinomoto Co., Inc. Raffinose synthetase gene, method of producing raffinose and transgenic plant
US5985605A (en) 1996-06-14 1999-11-16 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada DNA sequences encoding phytases of ruminal microorganisms
US5998700A (en) 1996-07-02 1999-12-07 The Board Of Trustees Of Southern Illinois University Plants containing a bacterial Gdha gene and methods of use thereof
US5750848A (en) 1996-08-13 1998-05-12 Monsanto Company DNA sequence useful for the production of polyhydroxyalkanoates
US6063756A (en) 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6093695A (en) 1996-09-26 2000-07-25 Monsanto Company Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and ctenocephalides SPP
BR9712457A (pt) 1996-10-29 1999-10-19 Calgene Llc Celulose sintetase vegetal e sequências promotoras
AP9901541A0 (en) 1996-11-20 1999-06-30 Ecogen Inc Broad-spectrum delta-endotoxins.
US6713063B1 (en) 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US6017534A (en) 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
US5942664A (en) 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
CA2275541A1 (en) 1996-12-19 1998-06-25 Yale University Bioreactive allosteric polynucleotides
US6171640B1 (en) 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6372211B1 (en) 1997-04-21 2002-04-16 Monsanto Technolgy Llc Methods and compositions for controlling insects
US6380466B1 (en) 1997-05-08 2002-04-30 Calgene Llc Production of improved rapeseed exhibiting yellow-seed coat
JP4126102B2 (ja) 1997-06-05 2008-07-30 カルジーン エル エル シー 脂肪アシル−ＣｏＡ：脂肪アルコールアシルトランスフェラーゼ
US6716474B2 (en) 1997-06-17 2004-04-06 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6441277B1 (en) 1997-06-17 2002-08-27 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6072103A (en) 1997-11-21 2000-06-06 Calgene Llc Pathogen and stress-responsive promoter for gene expression
US6060594A (en) 1997-12-18 2000-05-09 Ecogen, Inc. Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins
US6023013A (en) 1997-12-18 2000-02-08 Monsanto Company Insect-resistant transgenic plants
US6063597A (en) 1997-12-18 2000-05-16 Monsanto Company Polypeptide compositions toxic to coleopteran insects
US6653530B1 (en) 1998-02-13 2003-11-25 Calgene Llc Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds
US6107549A (en) 1998-03-10 2000-08-22 Monsanto Company Genetically engineered plant resistance to thiazopyr and other pyridine herbicides
US6284948B1 (en) 1998-05-18 2001-09-04 Pioneer Hi-Bred International, Inc. Genes and methods for control of nematodes in plants
US6444876B1 (en) 1998-06-05 2002-09-03 Calgene Llc Acyl CoA: cholesterol acyltransferase related nucleic acid sequences
CA2330024C (en) 1998-06-12 2012-01-24 Calgene Llc Polyunsaturated fatty acids in plants
ATE442435T1 (de) 1998-07-02 2009-09-15 Calgene Llc Diacylglyzerin-acyltransferase proteine
PT1097211E (pt) 1998-07-10 2007-07-12 Calgene Llc Expressão de péptidos eucarióticos em plastos vegetais
US6476294B1 (en) 1998-07-24 2002-11-05 Calgene Llc Plant phosphatidic acid phosphatases
AU771958B2 (en) 1998-08-04 2004-04-08 Cargill Incorporated Plant fatty acid desaturase promoters
AU5346099A (en) 1998-08-10 2000-03-06 Monsanto Company Methods for controlling gibberellin levels
US6365802B2 (en) 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
DE69941009D1 (de) 1998-11-17 2009-07-30 Monsanto Technology Llc Phosphonat metabolisierende pflanzen
US6531648B1 (en) 1998-12-17 2003-03-11 Syngenta Participations Ag Grain processing method and transgenic plants useful therein
PT1190068E (pt) 1999-04-15 2006-06-30 Calgene Llc Sequencias de acidos nucleicos para proteinas envolvidas na sintese de tocoferol
WO2000066742A2 (en) 1999-05-04 2000-11-09 Monsanto Technology Llc Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
CN1350587A (zh) 1999-05-13 2002-05-22 孟山都技术有限公司 植物的获得性抗性基因
JP2003501065A (ja) 1999-06-08 2003-01-14 カルジーン エルエルシー 脂肪酸のβ酸化に関わる蛋白質をコードする核酸配列とその使用法
US6770465B1 (en) 1999-06-09 2004-08-03 Calgene Llc Engineering B-ketoacyl ACP synthase for novel substrate specificity
US6723837B1 (en) 1999-07-12 2004-04-20 Monsanto Technology Llc Nucleic acid molecule and encoded protein associated with sterol synthesis and metabolism
US6501009B1 (en) 1999-08-19 2002-12-31 Monsanto Technology Llc Expression of Cry3B insecticidal protein in plants
WO2001019859A2 (en) 1999-09-15 2001-03-22 Monsanto Technology Llc LEPIDOPTERAN-ACTIVE BACILLUS THURINGIENSIS δ-ENDOTOXIN COMPOSITIONS AND METHODS OF USE
US6573361B1 (en) 1999-12-06 2003-06-03 Monsanto Technology Llc Antifungal proteins and methods for their use
BR0107474A (pt) 2000-01-06 2002-10-08 Monsanto Technology Llc Preparação de proteìnas e permuteìnas desalergenizadas
US6657046B1 (en) 2000-01-06 2003-12-02 Monsanto Technology Llc Insect inhibitory lipid acyl hydrolases
WO2001066704A2 (en) 2000-03-09 2001-09-13 Monsanto Technology Llc Methods for making plants tolerant to glyphosate and compositions thereof
US6518488B1 (en) 2000-07-21 2003-02-11 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with the β-oxidation pathway
WO2002008403A2 (en) 2000-07-25 2002-01-31 Calgene Llc Nucleic acid sequences encoding beta-ketoacyl-acp synthase and uses thereof
AU2002253836A1 (en) 2000-10-20 2002-08-19 Canji, Inc Aptamer-mediated regulation of gene expression
US7151204B2 (en) 2001-01-09 2006-12-19 Monsanto Technology Llc Maize chloroplast aldolase promoter compositions and methods for use thereof
DE10225066A1 (de) * 2002-06-06 2003-12-18 Basf Plant Science Gmbh Neue Expressionssysteme für Pflanzen
DK1682667T3 (da) * 2003-11-10 2010-08-23 Icon Genetics Gmbh RNA-virus afledt plantekspressionssystem
US20160230185A1 (en) 2013-03-14 2016-08-11 Monsanto Technology Llc Compositions and methods for controlling diabrotica
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
US8314290B2 (en) 2004-12-21 2012-11-20 Monsanto Technology Llc Temporal regulation of gene expression by MicroRNAs
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
AU2006203892B2 (en) 2005-01-07 2011-03-24 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
AR053279A1 (es) 2005-05-19 2007-04-25 Monsanto Technology Llc Regulacion post-transcripcional de la expresion genica
CA2625031C (en) 2005-10-13 2016-07-19 Monsanto Technology Llc Methods for producing hybrid seed
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
WO2007137075A2 (en) 2006-05-16 2007-11-29 Monsanto Technology Llc Use of non-agrobacterium bacterial species for plant transformation
EP2059596B1 (de) 2006-08-31 2017-10-04 Monsanto Technology, LLC Srna in phasen
CN101802215A (zh) 2006-10-12 2010-08-11 孟山都技术有限公司 植物微rna及其使用方法
WO2008103643A1 (en) 2007-02-20 2008-08-28 Monsanto Technology, Llc Invertebrate micrornas
US20120165387A1 (en) 2007-08-28 2012-06-28 Smolke Christina D General composition framework for ligand-controlled RNA regulatory systems
US9040774B2 (en) 2008-07-01 2015-05-26 Monsanto Technology Llc Recombinant DNA constructs encoding ribonuclease cleavage blockers and methods for modulating expression of a target gene
AU2009285624B2 (en) 2008-08-29 2013-12-05 Monsanto Technology Llc Novel Hemipteran and coleopteran active toxin proteins from Bacillus thuringiensis
TWI576432B (zh) 2009-04-07 2017-04-01 陶氏農業科學公司 序列特異性核酸酶之奈米粒子媒介式遞送技術
CN102428187A (zh) 2009-04-20 2012-04-25 孟山都技术公司 植物中的多重病毒抗性
US9873888B2 (en) 2009-10-23 2018-01-23 Monsanto Technology Llc Transgenic soybean plants and chromosomes
AU2011274811C1 (en) 2010-07-07 2015-09-24 Corteva Agriscience Llc Linear DNA molecule delivery using pegylated quantum dots for stable transformation in plants
AU2012230804B2 (en) 2011-03-23 2016-12-22 Corteva Agriscience Llc Quantum dot carrier peptide conjugates suitable for imaging and delivery applications in plants
AP2013007316A0 (en) 2011-07-01 2013-12-31 Monsanto Technology Llc Methods and compositions for selective regulation of protein expression
US20130145488A1 (en) 2011-12-06 2013-06-06 Iowa State University Research Foundation, Inc. Mesoporous silica nanoparticles suitable for co-delivery
US20130185823A1 (en) 2012-01-16 2013-07-18 Academia Sinica Mesoporous silica nanoparticle-mediated delivery of dna into arabidopsis root
US20140096284A1 (en) 2012-10-01 2014-04-03 Iowa State University Research Foundation, Inc. Method for the delivery of molecules lyophilized onto microparticles to plant tissues
US20150040268A1 (en) 2013-04-25 2015-02-05 Morflora Israel Ltd Methods and compositions for the delivery of nucleic acids to seeds
US20140356414A1 (en) 2013-06-03 2014-12-04 University Of Southern California Targeted Crosslinked Multilamellar Liposomes
EP3608412A3 (de) 2013-07-19 2020-04-08 Monsanto Technology LLC Zusammensetzungen und verfahren zur bekämpfung von leptinotarsa
US11208628B2 (en) 2013-08-09 2021-12-28 Massachusetts Institute Of Technology Nanobionic engineering of organelles and photosynthetic organisms
CN105829536A (zh) 2013-08-22 2016-08-03 纳幕尔杜邦公司 用于在不掺入选择性转基因标记的情况下，在植物基因组中产生基因修饰的方法，以及用于这种方法的组合物
WO2015153339A2 (en) 2014-04-01 2015-10-08 Monsanto Technology Llc Compositions and methods for controlling insect pests
AR101348A1 (es) 2014-07-29 2016-12-14 Monsanto Technology Llc Composiciones y métodos para el control de pestes por insectos
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
SG11201702749RA (en) 2014-10-16 2017-05-30 Monsanto Technology Llc Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
BR112017012900A2 (pt) 2014-12-19 2018-02-06 Agbiome Inc polinucleotídeo isolado ou um dna recombinante, célula de planta, planta, explante, semente, método para produzir uma célula de planta, método para controlar ervas daninhas, célula hospedeira
CN108349953B (zh) 2015-11-18 2022-06-17 孟山都技术公司 杀虫组合物和方法
US10612037B2 (en) 2016-06-20 2020-04-07 Monsanto Technology Llc Insecticidal proteins toxic or inhibitory to hemipteran pests
BR112019002586A2 (pt) 2016-08-09 2019-05-21 Syngenta Participations Ag proteínas inseticidas
AR109844A1 (es) 2016-10-27 2019-01-30 Syngenta Participations Ag Proteínas insecticidas
WO2018111946A1 (en) 2016-12-12 2018-06-21 Integrated Dna Technologies, Inc. Genome editing detection
WO2018132325A1 (en) 2017-01-12 2018-07-19 Syngenta Participations Ag Insecticidal proteins
EP3573448A4 (de) 2017-01-28 2020-09-02 Inari Agriculture, Inc. Neuartige pflanzenzellen, pflanzen und samen
KR20210054507A (ko) 2018-07-25 2021-05-13 인바이오 사이언시스 인터내셔널 게엠베하 주입 시스템, 주입 툴 및 주입 방법
US20230227830A1 (en) * 2020-06-20 2023-07-20 Halo-Bio Rnai Therapeutics, Inc. Methods and compositions of rna nanostructures for replication and sub-genomic expression by rna-directed rna polymerase
MX2024000992A (es) 2021-07-23 2024-07-09 Flagship Pioneering Innovations Vii Llc Composiciones para el control fungico y metodos relacionados.

Also Published As

Publication number Publication date
WO2024229359A3 (en) 2024-12-05
AR132588A1 (es) 2025-07-16
WO2024229359A2 (en) 2024-11-07

Similar Documents

Publication Publication Date Title
US12529067B2 (en) Methods for modifying plants with a recombinant RNA molecule
US20250230452A1 (en) Polynucleotides for modifying organisms
US20150203866A1 (en) Methods and compositions for plant pest control
US11578338B2 (en) Hemipteran active insecticidal protein
CN118556127A (zh) 用于修饰生物体的多核苷酸
EP4705474A2 (de) Künstliche tymovirale satelliten rnas
EP4705478A1 (de) Künstliche morellivirale satelliten-rnas
EP4705473A2 (de) Künstliche solmoviridae-satelliten-rnas
WO2024229398A1 (en) Artificial amalgavirus satellite rnas
WO2024229385A1 (en) Artificial ghabrivirales satellite rnas
WO2024229395A1 (en) Partitiviral satellite rna amplification systems for plants
EP4705472A1 (de) Künstliche secoviridae-satelliten-rnas
EP4705470A1 (de) Künstliche tombusviridae-satelliten-rnas
EP4705477A1 (de) Endornavirale satelliten-rna-amplifikationssysteme für pflanzen
CN121794387A (zh) 人工伴生豇豆花叶病毒科卫星rna
CN121816422A (zh) 人工混合病毒属卫星rna
CN118922549A (zh) 用于修饰生物体的多核苷酸

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20251030

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR