EP4705291A1 - Ikk-alpha-inhibitoren - Google Patents
Ikk-alpha-inhibitorenInfo
- Publication number
- EP4705291A1 EP4705291A1 EP24726703.2A EP24726703A EP4705291A1 EP 4705291 A1 EP4705291 A1 EP 4705291A1 EP 24726703 A EP24726703 A EP 24726703A EP 4705291 A1 EP4705291 A1 EP 4705291A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- indazol
- pyridin
- amino
- pyrrolo
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2306601.2A GB202306601D0 (en) | 2023-05-04 | 2023-05-04 | Inhibitor compounds |
| PCT/GB2024/051180 WO2024228035A1 (en) | 2023-05-04 | 2024-05-03 | Ikk-alpha inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP4705291A1 true EP4705291A1 (de) | 2026-03-11 |
Family
ID=86763229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24726703.2A Pending EP4705291A1 (de) | 2023-05-04 | 2024-05-03 | Ikk-alpha-inhibitoren |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP4705291A1 (de) |
| CN (1) | CN121443594A (de) |
| AU (1) | AU2024265368A1 (de) |
| GB (1) | GB202306601D0 (de) |
| WO (1) | WO2024228035A1 (de) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| MXPA02012903A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como inhibidores de angiogenesis. |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| WO2008132121A1 (en) * | 2007-04-26 | 2008-11-06 | Glaxo Group Limited | Lh-indazole-3-amine compounds as ikk1 inhibitors |
| US8648069B2 (en) * | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| WO2023218201A1 (en) * | 2022-05-11 | 2023-11-16 | Cancer Research Technology Limited | Ikk inhibitors |
-
2023
- 2023-05-04 GB GBGB2306601.2A patent/GB202306601D0/en not_active Ceased
-
2024
- 2024-05-03 WO PCT/GB2024/051180 patent/WO2024228035A1/en not_active Ceased
- 2024-05-03 CN CN202480045347.XA patent/CN121443594A/zh active Pending
- 2024-05-03 EP EP24726703.2A patent/EP4705291A1/de active Pending
- 2024-05-03 AU AU2024265368A patent/AU2024265368A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB202306601D0 (en) | 2023-06-21 |
| WO2024228035A1 (en) | 2024-11-07 |
| CN121443594A (zh) | 2026-01-30 |
| AU2024265368A1 (en) | 2025-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: UNKNOWN |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20251112 |
|
| AK | Designated contracting states |
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