EP4375376A2 - Variantes de transcriptase inverse mmlv - Google Patents
Variantes de transcriptase inverse mmlv Download PDFInfo
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- EP4375376A2 EP4375376A2 EP24167618.8A EP24167618A EP4375376A2 EP 4375376 A2 EP4375376 A2 EP 4375376A2 EP 24167618 A EP24167618 A EP 24167618A EP 4375376 A2 EP4375376 A2 EP 4375376A2
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- mutation
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
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- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762490492P | 2017-04-26 | 2017-04-26 | |
| PCT/US2018/029641 WO2018200867A1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
| EP18791768.7A EP3592847B1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
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| EP18791768.7A Division EP3592847B1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
| EP18791768.7A Division-Into EP3592847B1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
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| EP18791768.7A Active EP3592847B1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
| EP24167618.8A Pending EP4375376A2 (fr) | 2017-04-26 | 2018-04-26 | Variantes de transcriptase inverse mmlv |
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| EP18791768.7A Active EP3592847B1 (fr) | 2017-04-26 | 2018-04-26 | Variants de transcriptase inverse du virus de la leucémie murine de moloney (mmlv) |
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| EP (2) | EP3592847B1 (fr) |
| CN (1) | CN110637084A (fr) |
| SG (1) | SG11201908596WA (fr) |
| WO (1) | WO2018200867A1 (fr) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DK3752634T3 (da) * | 2018-02-13 | 2022-10-24 | Illumina Inc | DNA Sequencing Using Hydrogel Beads / DNA-sekventering ved anvendelse af hydrogelkorn |
| CN112442493A (zh) * | 2019-08-30 | 2021-03-05 | 广东菲鹏生物有限公司 | 热稳定的逆转录酶 |
| EP4073241A2 (fr) | 2019-12-11 | 2022-10-19 | 10X Genomics, Inc. | Variants de transcriptase inverse |
| CN111647576B (zh) * | 2020-06-24 | 2021-02-09 | 南京诺唯赞生物科技股份有限公司 | 一种热稳定性逆转录酶突变体及其应用 |
| CN112011596A (zh) * | 2020-09-11 | 2020-12-01 | 深圳华大因源医药科技有限公司 | 一种同时检测多种微生物基因组的方法、溶液和试剂盒 |
| WO2022232571A1 (fr) * | 2021-04-30 | 2022-11-03 | 10X Genomics, Inc. | Variants de rt de fusion pour une performance améliorée |
| CN113355303B (zh) * | 2021-06-07 | 2023-06-16 | 中元汇吉生物技术股份有限公司 | 一种m-mlv逆转录酶突变体及其应用 |
| WO2022265965A1 (fr) * | 2021-06-14 | 2022-12-22 | 10X Genomics, Inc. | Variants de la transcriptase inverse pour une performance améliorée |
| CN113817707B (zh) * | 2021-11-23 | 2022-02-22 | 中国医学科学院北京协和医院 | 一种突变重组逆转录酶及其制备方法和应用 |
| WO2023114473A2 (fr) * | 2021-12-16 | 2023-06-22 | 10X Genomics, Inc. | Variants de transcriptases inverses recombinantes pour une performance améliorée |
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| US6265552B1 (en) | 1993-07-30 | 2001-07-24 | Affymax Technologies N.V. | Biotinylation of proteins |
| US20100105112A1 (en) | 2006-08-07 | 2010-04-29 | Christian Holtze | Fluorocarbon emulsion stabilizing surfactants |
| US20140155295A1 (en) | 2012-08-14 | 2014-06-05 | 10X Technologies, Inc. | Capsule array devices and methods of use |
| US20140378345A1 (en) | 2012-08-14 | 2014-12-25 | 10X Technologies, Inc. | Compositions and methods for sample processing |
| US20150292988A1 (en) | 2014-04-10 | 2015-10-15 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
| US20150376700A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| US20150376605A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods and Compositions for Sample Analysis |
| US20150376609A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods of Analyzing Nucleic Acids from Individual Cells or Cell Populations |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ522500A (en) * | 2000-05-26 | 2004-10-29 | Invitrogen Corp | Thermostable reverse transcriptases and uses thereof |
| JP5203200B2 (ja) * | 2005-08-10 | 2013-06-05 | アジレント・テクノロジーズ・インク | 変異体逆転写酵素および使用方法 |
| GB0806562D0 (en) * | 2008-04-10 | 2008-05-14 | Fermentas Uab | Production of nucleic acid |
| CA2834291A1 (fr) * | 2011-04-25 | 2012-11-01 | Biorad Laboratories, Inc. | Procedes et compositions pour l'analyse d'acide nucleique |
| KR20160113177A (ko) * | 2014-01-22 | 2016-09-28 | 라이프 테크놀로지스 코포레이션 | 고온 핵산 합성에서 이용하기 위한 신규한 역전사효소 |
| EP3191605B1 (fr) * | 2014-09-09 | 2022-07-27 | The Broad Institute, Inc. | Procédé à base de gouttelettes et appareil pour l'analyse composite d'acide nucléique de cellules uniques |
| US9580698B1 (en) * | 2016-09-23 | 2017-02-28 | New England Biolabs, Inc. | Mutant reverse transcriptase |
-
2018
- 2018-04-26 SG SG11201908596W patent/SG11201908596WA/en unknown
- 2018-04-26 WO PCT/US2018/029641 patent/WO2018200867A1/fr unknown
- 2018-04-26 EP EP18791768.7A patent/EP3592847B1/fr active Active
- 2018-04-26 EP EP24167618.8A patent/EP4375376A2/fr active Pending
- 2018-04-26 CN CN201880032804.6A patent/CN110637084A/zh active Pending
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| US6265552B1 (en) | 1993-07-30 | 2001-07-24 | Affymax Technologies N.V. | Biotinylation of proteins |
| US20100105112A1 (en) | 2006-08-07 | 2010-04-29 | Christian Holtze | Fluorocarbon emulsion stabilizing surfactants |
| US20140155295A1 (en) | 2012-08-14 | 2014-06-05 | 10X Technologies, Inc. | Capsule array devices and methods of use |
| US20140378345A1 (en) | 2012-08-14 | 2014-12-25 | 10X Technologies, Inc. | Compositions and methods for sample processing |
| US20150292988A1 (en) | 2014-04-10 | 2015-10-15 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
| US20150376700A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| US20150376605A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods and Compositions for Sample Analysis |
| US20150376609A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods of Analyzing Nucleic Acids from Individual Cells or Cell Populations |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3592847A4 (fr) | 2021-05-05 |
| CN110637084A (zh) | 2019-12-31 |
| EP3592847A1 (fr) | 2020-01-15 |
| EP3592847B1 (fr) | 2024-06-05 |
| SG11201908596WA (en) | 2019-11-28 |
| WO2018200867A1 (fr) | 2018-11-01 |
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