EP4127043A1 - A composite material formed by using boron during production of a polyurethane base material - Google Patents

A composite material formed by using boron during production of a polyurethane base material

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Publication number
EP4127043A1
EP4127043A1 EP20735248.5A EP20735248A EP4127043A1 EP 4127043 A1 EP4127043 A1 EP 4127043A1 EP 20735248 A EP20735248 A EP 20735248A EP 4127043 A1 EP4127043 A1 EP 4127043A1
Authority
EP
European Patent Office
Prior art keywords
weight
composite material
boron compound
polyurethane
base material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20735248.5A
Other languages
German (de)
French (fr)
Inventor
Emir TEM ZKAN
Gülden ERO LU
Hüseyin DEL GÖZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Safas Saf Plastik Sanayi Ve Ticaret AS
Original Assignee
Safas Saf Plastik Sanayi Ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Safas Saf Plastik Sanayi Ve Ticaret AS filed Critical Safas Saf Plastik Sanayi Ve Ticaret AS
Publication of EP4127043A1 publication Critical patent/EP4127043A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0066—Use of inorganic compounding ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/16—Catalysts
    • C08G18/18—Catalysts containing secondary or tertiary amines or salts thereof
    • C08G18/20—Heterocyclic amines; Salts thereof
    • C08G18/2045—Heterocyclic amines; Salts thereof containing condensed heterocyclic rings
    • C08G18/2063—Heterocyclic amines; Salts thereof containing condensed heterocyclic rings having two nitrogen atoms in the condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/16—Catalysts
    • C08G18/22—Catalysts containing metal compounds
    • C08G18/24—Catalysts containing metal compounds of tin
    • C08G18/244—Catalysts containing metal compounds of tin tin salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3271—Hydroxyamines
    • C08G18/3275—Hydroxyamines containing two hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3271—Hydroxyamines
    • C08G18/3278—Hydroxyamines containing at least three hydroxy groups
    • C08G18/3281—Hydroxyamines containing at least three hydroxy groups containing three hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/66—Compounds of groups C08G18/42, C08G18/48, or C08G18/52
    • C08G18/6666—Compounds of group C08G18/48 or C08G18/52
    • C08G18/667—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6681—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/32 or C08G18/3271 and/or polyamines of C08G18/38
    • C08G18/6688—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/32 or C08G18/3271 and/or polyamines of C08G18/38 with compounds of group C08G18/3271
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/76—Polyisocyanates or polyisothiocyanates cyclic aromatic
    • C08G18/7614—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring
    • C08G18/7621—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring being toluene diisocyanate including isomer mixtures
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
    • C08J9/14—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
    • C08J9/143—Halogen containing compounds
    • C08J9/144—Halogen containing compounds containing carbon, halogen and hydrogen only
    • C08J9/145—Halogen containing compounds containing carbon, halogen and hydrogen only only chlorine as halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/38—Boron-containing compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2101/00—Manufacture of cellular products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2110/00—Foam properties
    • C08G2110/0083—Foam properties prepared using water as the sole blowing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2203/00—Foams characterized by the expanding agent
    • C08J2203/14—Saturated hydrocarbons, e.g. butane; Unspecified hydrocarbons
    • C08J2203/142—Halogenated saturated hydrocarbons, e.g. H3C-CF3
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2207/00—Foams characterised by their intended use
    • C08J2207/10—Medical applications, e.g. biocompatible scaffolds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2207/00—Foams characterised by their intended use
    • C08J2207/12—Sanitary use, e.g. diapers, napkins or bandages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2375/00—Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
    • C08J2375/04—Polyurethanes
    • C08J2375/08—Polyurethanes from polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/38—Boron-containing compounds
    • C08K2003/387—Borates

Definitions

  • the invention relates to a composite material formed by using boron during production of a polyurethane base material.
  • wound healing materials produced using Boron are available, which materials are obtained by adding boron to the structures such as collagen, hydrogel. Wound healing materials formed by adding Boron to a polyurethane material are not included in the state of the art.
  • the patent document no. TR 2019/12225 discloses polyurethane foam produced for hygiene.
  • the amount of boron added to the foam contains 10% borax.
  • Said patent document disclosed a composite material obtained by adding 9-35% boron compound to a polyol during polyurethane production. Therefore, the ratio of the boron compound in the composite material is provided to be 5-23%. Said patent document does not disclose the wound healing property of the composite material.
  • the patent US8147857 describes the production of a polyurethane gel as an antiseptic wound dressing.
  • the present invention relates to the use of a boron compound to enable the flexible polyurethane foam to gain wound-healing properties. Said document does not disclose the production of the polyurethane foam material.
  • the wound healing property of said polyurethane gel is not mentioned.
  • boron was added to a wide variety of materials. During this addition, boron is added to the foam by an impregnation method, but after this method, the foam loses its original property. The pores of the foam which is normally flexible, is an open cell foam and is air-permeable are closed after the boron impregnation, thus the permeability property is lost and the foam hardens. This technical problem in the state of the art needs to be overcome.
  • the object of the invention is to produce a composite material by adding boron to flexible polyurethane foam.
  • Said composite material is used in the fields such as medical, cleaning, mattress, upholstery (sofa), bras, and shoe insoles.
  • the composite material used for medical purposes is used to heal wounds.
  • the composite material formed by adding boron to the flexible polyurethane foam does not lose its flexible and air-permeable properties. Therefore, in foams which are normally flexible, are open cell foams and are air-permeable, the pores of the composite material obtained after the addition of a boron compound during the production of a base material are not closed, so the permeability is not lost and the foam does nor harden.
  • the amount of boron added to the material is important to have specific values. This value should be at least 40%.
  • Figure 1 is a schematic perspective view of a composite material according to the invention.
  • the invention relates to a composite material (1) formed by adding a boron compound (1.2) to a base material (1.1). Said composite material (1) will be used especially for medical purposes and has a wound healing property.
  • the composite material (1) of the invention includes a base material (1.1) and a boron compound (1.2) added to said base material (1.1) at a predetermined ratio.
  • Said base material (2) is flexible and is, but not limited to, a polyurethane material in a preferred embodiment of the invention.
  • the polyurethane material is preferably, but not limited to, a foam.
  • the boron compound (1.2) is added to the base material (1.1) during the production of the base material (1.1). Boron Compound (1.2) is not impregnated to Polyurethane base materials (1.1) in the state of the art with the invention. The boron compound (1.2) is added to the base material (1.1) during the production of the base material ( 1.1 ), so that a composite material (1) is obtained.
  • the pores of the base material (1.1) are formed during the production.
  • the particles of boron compound (1.2) incorporated in the production system are positioned around the pores. Therefore, the boron compound (1.2) does not cause any blockage in the pores.
  • the boron compound (1.1) is present in powder form, and the boron compound (1.2) is dispersed in the polyol and added to the base material (1.1).
  • the ratio of the boron compound (1.2) added to the base material (1.1) is 40% to 45%.
  • the composite material (1) of the invention has wound healing properties as well as antibacterial properties. It may also be used in all areas that require hygiene.
  • the mixture of polyol and boron compound (1.2) of equal amounts during production of polyurethane base material (1.1) is added to the production system.
  • the ratio of the boron compound (1.2) in the composite material (1) is allowed to be at least 40% by adding the mixture obtained with the addition of boron compound (1.2) of 50% to the polyol to the base material (1.1).
  • the pores are not blocked and the polyurethane base material (1.1) is not lost, as a result it does not harden, as the boron compound (1.2) is added to the system at this ratio during the production of the polyurethane base material (1.1).
  • Table 1 provides the content of the composite material (1) and the percentages by weight of the content. Table 1. Chemical content of the composite material (1) and the percentages by weight therefor
  • the composite material (1.1) contains 50% boron compound (wound healing agent) (1.2) in 80% to 90% by weight of poly ether polyol (raw material for polyurethane) and/or 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis (dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1% by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of polyether modified polysi
  • borax pentahydrate (Etibor-48) (Na 2 B 4 0 7 .5H 2 0), or borax decahydrate (Na 2 B 4 O 7 .10H 2 O), or boric acid (Etidot-67) (H3BO3), or anhydrous borax (Etibor-68) (Na 2 B 4 0 ?
  • the boron compound (1.2) is suspended in the polyether polyol contained in the base material (1.1).
  • the above-mentioned boron compounds (1.2) are prepared by suspending in the polyol and the solution thereof contains 50% by weight of boron compound (1) and 50% by weight of polyether polyol.
  • the base material (El) contains 40 to 45% by weight of boron compound (1.2).
  • the composite material (1) has the ability to heal wounds.
  • the composite material (1) has a therapeutic effect, such as healing wounds on the skin.
  • the composite material is produced according to the following method (100) steps:
  • the second step adding 50% boron compound (wound healing agent) (1.2) in 80% to 90% by weight of polyether polyol (raw material for polyurethane) and/or 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis (dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1% by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of polyether modified polysiloxane
  • the third step forming the composite material by a reaction of the materials from the mixer in a tunnel.
  • the composite material (1) of the invention will be used in the fields such as medical, cleaning, mattress, upholstery (sofa), bras, and shoe insoles.
  • the invention may be used in dressings, patient cleansing sponges, bandages, cleansing sponges, sickbeds, normal beds, products in contact with people (bra, shoe insole), etc.

Abstract

The invention relates to a composite material (1) comprising a base material (1.1) and a boron compound (1.2) added to said base material (1.1) at a predetermined ratio, said composite material comprises a boron compound (1.2) which is allowed to be at least 40% by adding the mixture obtained by suspending 50% by weight of boron compound (1.2) in polyether polyol to the base material (1.1).

Description

A COMPOSITE MATERIAL FORMED BY USING BORON DURING PRODUCTION OF A POLYURETHANE BASE MATERIAL
Technical Field
The invention relates to a composite material formed by using boron during production of a polyurethane base material.
Prior Art
In the state of the art, wound healing materials produced using Boron are available, which materials are obtained by adding boron to the structures such as collagen, hydrogel. Wound healing materials formed by adding Boron to a polyurethane material are not included in the state of the art.
In the patent document no. US5104660 of said art, a wound healing bandage is mentioned, which is obtained by adding boron to collagen. In said patent document, addition of Boron to the polyurethane material and its wound healing property are not mentioned.
In the patent document no. US9655990 B2 in the state of the art, a boron-containing hydrogel is mentioned. In said patent document, addition of Boron to the polyurethane material and its wound healing property are not mentioned.
In the article titled ‘ he wound healing activity of Sodium pentaborate pentahydrate (NaB) containing hydrogel ” published in A.Dogan et. al., International Symposium on Boron, 17- 19 April 2019 held by R.T. Ministry of Energy and Natural Resources, the addition of Boron to a material such as hydrogel and wound healing property of said material were mentioned. In said publication, the addition of Boron in to the polyurethane material was not mentioned.
The patent document no. US204/0202703A1 in the state of the art discloses that the wound healing property of the material is obtained by adding silver particles to the polymer material. In said patent document, the addition of Boron in the polyurethane material is not mentioned. In the article titled “ Dysprosium-Borate Nanoparticles Induce Wound Healing in HaCaT Cell Line ” published in Batuhan Turhan Bozkurt et. ah, International Symposium on Boron, 17-19 April 2019 held by R.T. Ministry of Energy and Natural Resources, wound healing properties of a solution containing Dysprosium-Borate Nanoparticles are addressed. In said publication, the addition of Boron to the polyurethane material was not mentioned.
In the article titled “Treatment of Diabetic Wounds with Nano-Boric Acid Particle- Impregnated Polyurethane Foams” published in Rana Kapukaya et ah, International Symposium on Boron, 17-19 April 2019 held by R.T. Ministry of Energy and Natural Resources, impregnation of polyurethane foam with nano-boric acid particles was mentioned. After the foam is produced in the first step in said study, the foam is impregnated with nano-boric acid particles of 4% prepared as a solution. Said document does not disclose how much of this ratio is impregnated into the foam. After the impregnation, the pores of the foam are closed, and then the foam hardens. Said foam has been observed to have a wound healing effect. However, the study has disadvantages in that the structural properties of the foam are lost as the pores of the foam are blocked and the foam hardens.
The patent document no. TR 2019/12225 discloses polyurethane foam produced for hygiene. In said document, the amount of boron added to the foam contains 10% borax. Said patent document disclosed a composite material obtained by adding 9-35% boron compound to a polyol during polyurethane production. Therefore, the ratio of the boron compound in the composite material is provided to be 5-23%. Said patent document does not disclose the wound healing property of the composite material.
The patent US8147857 describes the production of a polyurethane gel as an antiseptic wound dressing. However, the present invention relates to the use of a boron compound to enable the flexible polyurethane foam to gain wound-healing properties. Said document does not disclose the production of the polyurethane foam material. In addition, the wound healing property of said polyurethane gel is not mentioned.
In the technical prior art documents listed above, boron was added to a wide variety of materials. During this addition, boron is added to the foam by an impregnation method, but after this method, the foam loses its original property. The pores of the foam which is normally flexible, is an open cell foam and is air-permeable are closed after the boron impregnation, thus the permeability property is lost and the foam hardens. This technical problem in the state of the art needs to be overcome.
On the other hand, in the state of the art, no hardening and structure change should occur when the foams with a wound healing property are produced. Considering that the said foams will contact the human body, hard and air-tight foams are not suitable for this purpose.
Brief Description of the Invention:
The object of the invention is to produce a composite material by adding boron to flexible polyurethane foam. Said composite material is used in the fields such as medical, cleaning, mattress, upholstery (sofa), bras, and shoe insoles. The composite material used for medical purposes is used to heal wounds.
According to the invention, the composite material formed by adding boron to the flexible polyurethane foam does not lose its flexible and air-permeable properties. Therefore, in foams which are normally flexible, are open cell foams and are air-permeable, the pores of the composite material obtained after the addition of a boron compound during the production of a base material are not closed, so the permeability is not lost and the foam does nor harden.
In order for the polyurethane foam material of the invention to have wound healing properties, the amount of boron added to the material is important to have specific values. This value should be at least 40%.
Description of the Figures
Figure 1 is a schematic perspective view of a composite material according to the invention.
Description of the References in the Figures
For a better understanding of the invention, the numbers in the figures are given below:
1. Composite material 1.1 Base material 1.2 Boron Compound
Detailed Description of the Invention:
The invention relates to a composite material (1) formed by adding a boron compound (1.2) to a base material (1.1). Said composite material (1) will be used especially for medical purposes and has a wound healing property.
The composite material (1) of the invention includes a base material (1.1) and a boron compound (1.2) added to said base material (1.1) at a predetermined ratio. Said base material (2) is flexible and is, but not limited to, a polyurethane material in a preferred embodiment of the invention. The polyurethane material is preferably, but not limited to, a foam.
The boron compound (1.2) is added to the base material (1.1) during the production of the base material (1.1). Boron Compound (1.2) is not impregnated to Polyurethane base materials (1.1) in the state of the art with the invention. The boron compound (1.2) is added to the base material (1.1) during the production of the base material ( 1.1 ), so that a composite material (1) is obtained.
The pores of the base material (1.1) are formed during the production. At the same time, the particles of boron compound (1.2) incorporated in the production system are positioned around the pores. Therefore, the boron compound (1.2) does not cause any blockage in the pores.
The boron compound (1.1) is present in powder form, and the boron compound (1.2) is dispersed in the polyol and added to the base material (1.1). The ratio of the boron compound (1.2) added to the base material (1.1) is 40% to 45%. The composite material (1) of the invention has wound healing properties as well as antibacterial properties. It may also be used in all areas that require hygiene.
According to the invention, the mixture of polyol and boron compound (1.2) of equal amounts during production of polyurethane base material (1.1) is added to the production system. In this application of the present invention, the ratio of the boron compound (1.2) in the composite material (1) is allowed to be at least 40% by adding the mixture obtained with the addition of boron compound (1.2) of 50% to the polyol to the base material (1.1). The pores are not blocked and the polyurethane base material (1.1) is not lost, as a result it does not harden, as the boron compound (1.2) is added to the system at this ratio during the production of the polyurethane base material (1.1).
Table 1 provides the content of the composite material (1) and the percentages by weight of the content. Table 1. Chemical content of the composite material (1) and the percentages by weight therefor
The composite material (1.1) contains 50% boron compound (wound healing agent) (1.2) in 80% to 90% by weight of poly ether polyol (raw material for polyurethane) and/or 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis (dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1% by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of polyether modified polysiloxane (surfactant) and/or 15% to 25% by weight of 2, 4:2, 6 toluene diisocyanate (80:20) (raw material for polyurethane).
As a boron compound (1.2) according to the invention, borax pentahydrate (Etibor-48) (Na2B407.5H20), or borax decahydrate (Na2B4O7.10H2O), or boric acid (Etidot-67) (H3BO3), or anhydrous borax (Etibor-68) (Na2B40?), or zinc borate (2Zh0.3B2q3.3,5H2q), or boron oxide (B2O3), or ground colemanite (2CaO.3B2O3.5H2O), or ground ulexite (Na20.2Ca0.5B203.16H20).
According to the invention the boron compound (1.2) is suspended in the polyether polyol contained in the base material (1.1). The above-mentioned boron compounds (1.2) are prepared by suspending in the polyol and the solution thereof contains 50% by weight of boron compound (1) and 50% by weight of polyether polyol.
In the preferred embodiment of the invention, the base material (El) contains 40 to 45% by weight of boron compound (1.2).
By using the boron compound (E2) at these ratios, the composite material (1) has the ability to heal wounds. Thus, the composite material (1) has a therapeutic effect, such as healing wounds on the skin.
The composite material is produced according to the following method (100) steps:
In the first step, allowing the boron compound ( 1.2) in the form of powder to disperse and suspend in polyether polyol in order to increase its processability,
In the second step, adding 50% boron compound (wound healing agent) (1.2) in 80% to 90% by weight of polyether polyol (raw material for polyurethane) and/or 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis (dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1% by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of polyether modified polysiloxane (surfactant) and/or 15% to 25% by weight of 2, 4:2, 6 toluene diisocyanate (80:20) (raw material for polyurethane) to a mixer,
In the third step, forming the composite material by a reaction of the materials from the mixer in a tunnel.
Industrial Applicability of the Invention:
The composite material (1) of the invention will be used in the fields such as medical, cleaning, mattress, upholstery (sofa), bras, and shoe insoles.
Therefore, the invention may be used in dressings, patient cleansing sponges, bandages, cleansing sponges, sickbeds, normal beds, products in contact with people (bra, shoe insole), etc.
The invention is not limited to the above exemplary embodiments, and one skilled in the art can easily demonstrate the other embodiments of the invention. These should be considered within the scope of the protection claimed by the claims of the invention.

Claims

1. A composite material (1) comprising a base material (1.1) and a boron compound (1.2) added to said base material (1.1) at a predetermined ratio, said composite material is characterized by a boron compound (1.2) which is allowed to be at least 40% by adding the mixture obtained by suspending 50% by weight of boron compound (1.2) in polyether polyol to the base material (1.1).
2. A composite material (1) according to claim 1, characterized by a base material (1.1) containing 40% to 45% by weight of boron compound (1.2).
3. A composite material (1) according to claim 2, characterized by a base material
(1.1) containing 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis (dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1 % by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of polyether modified polysiloxane (surfactant) and/or 15% to 25% by weight of 2, 4:2, 6 toluene diisocyanate (80:20) (raw material for polyurethane).
4. A composite material (1) according to claim 3, characterized by a boron compound
(1.2) which may be borax pentahydrate (Etibor-48) (NaimCbAthO), or borax decahydrate (NaimCb.lOthO), or boric acid (Etidot-67) (H3BO3), or anhydrous borax (Etibor-68) (NaiEEO?), or zinc borate (2Zh0.3B2q3.3,5H2q), or boron oxide (B2O3), or ground colemanite (2CaO.3B2O3.5H2O), or ground ulexite (Na20.2Ca0.5B203.16H2O).
5. A composite material (1) according to any one of the preceding claims, characterized in that said composite material has a therapeutic effect, such as healing wounds on the skin.
6. A method of producing a composite material, said method is characterized by comprising the following steps:
In the first step, allowing the boron compound (1.2) in the form of powder to disperse and suspend in polyether polyol in order to increase its processability,
In the second step, adding 50% boron compound (wound healing agent) (1.2) in 80% to 90% by weight of polyether polyol (raw material for polyurethane) and/or 0% to 5% by weight of methylene chloride (foaming agent) and/or 0.5% to 3% of water (raw material for foaming reaction) and/or 0.05% to 0.5 by weight of tin octoate (polyurethane catalyst) and/or 0.001 to 0.01 by weight of 70% bis
(dimethyl amino ethyl) ether diluted in 30% propylene glycol (foaming catalyst) and/or 0.001% to 0.04% by weight of 33% triethylene diamine 67% dipropylene glycol solution (gelling catalyst) and/or 0% to 0.1% by weight of %33 urea solution (cross linker) and/or 0% to 0.1% by weight of diethanol amine/triethanolamine (cross linker) and/or 0.1% to 0.8% by weight of poly ether modified polysiloxane (surfactant) and/or 15% to 25% by weight of 2, 4:2, 6 toluene diisocyanate (80:20) (raw material for polyurethane) to a mixer,
In the third step, forming the composite material by a reaction of the materials from the mixer in a tunnel.
EP20735248.5A 2020-04-02 2020-05-28 A composite material formed by using boron during production of a polyurethane base material Pending EP4127043A1 (en)

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PCT/TR2020/050461 WO2021201792A1 (en) 2020-04-02 2020-05-28 A composite material formed by using boron during production of a polyurethane base material

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DE10316156B3 (en) * 2003-04-09 2004-10-14 Beiersdorf Ag Antimicrobial polymer materials and their use as a wound dressing
JP2005154533A (en) * 2003-11-25 2005-06-16 Nippon Polyurethane Ind Co Ltd Method for producing flexible polyurethane foam
FR2873300B1 (en) * 2004-07-22 2007-03-09 Compart Sas Soc Par Actions Si FIRECUT MATERIAL
DE102004061406A1 (en) * 2004-12-21 2006-07-06 Bayer Innovation Gmbh Infection-resistant polyurethane foams, process for their preparation and use in antiseptic-treated wound dressings
PL1964580T3 (en) * 2007-03-01 2011-05-31 Moelnlycke Health Care Ab Silver-containing foam structure
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