EP4103168A4 - Procédé de préparation d'acides gamma-amino-butyriques et de leurs analogues - Google Patents
Procédé de préparation d'acides gamma-amino-butyriques et de leurs analoguesInfo
- Publication number
- EP4103168A4 EP4103168A4 EP21753915.4A EP21753915A EP4103168A4 EP 4103168 A4 EP4103168 A4 EP 4103168A4 EP 21753915 A EP21753915 A EP 21753915A EP 4103168 A4 EP4103168 A4 EP 4103168A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- analogs
- preparation
- amino butyric
- butyric acids
- gamma amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- QWCKQJZIFLGMSD-UHFFFAOYSA-N alpha-aminobutyric acid Chemical class CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C07C227/20—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN202011006475 | 2020-02-14 | ||
| PCT/IN2021/050141 WO2021161346A1 (fr) | 2020-02-14 | 2021-02-13 | Procédé de préparation d'acides gamma-amino-butyriques et de leurs analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4103168A1 EP4103168A1 (fr) | 2022-12-21 |
| EP4103168A4 true EP4103168A4 (fr) | 2024-04-24 |
Family
ID=77293016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP21753915.4A Pending EP4103168A4 (fr) | 2020-02-14 | 2021-02-13 | Procédé de préparation d'acides gamma-amino-butyriques et de leurs analogues |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4103168A4 (fr) |
| JP (1) | JP7436689B2 (fr) |
| WO (1) | WO2021161346A1 (fr) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002241358A (ja) | 2001-02-15 | 2002-08-28 | Nippon Soda Co Ltd | オキシム基を有する化合物及び殺虫・殺ダニ剤 |
| JP4250887B2 (ja) | 2001-10-22 | 2009-04-08 | 三菱化学株式会社 | アミド化合物の製造方法 |
| JP4562370B2 (ja) | 2003-10-02 | 2010-10-13 | 独立行政法人科学技術振興機構 | 転位不飽和化合物の製造方法 |
| AU2005256945B2 (en) | 2004-06-21 | 2008-11-13 | Upjohn Us 1 Llc | Preparation of pregabalin and related compounds |
| WO2006110783A2 (fr) | 2005-04-11 | 2006-10-19 | Teva Pharmaceutical Industries Ltd. | Procede de fabrication de (s)-pregabaline |
| US8293926B2 (en) | 2005-12-09 | 2012-10-23 | Sumitomo Chemical Company, Limited | Method of producing optically active 4-amino-3-substituted phenylbutanoic acid |
| WO2008062460A2 (fr) * | 2006-10-06 | 2008-05-29 | Cadila Healthcare Limited | Formes cristallines de la prégabaline |
| WO2009141362A2 (fr) | 2008-05-21 | 2009-11-26 | Sandoz Ag | Procédé pour l'hydrolyse enzymatique stéréosélective d'un ester d'acide 5-méthyl-3-nitrométhyl-hexanoïque |
| WO2010061403A2 (fr) | 2008-11-26 | 2010-06-03 | Ind-Swift Laboratories Limited | Procédé pour préparer de la (s)-prégabaline très pure |
| WO2012093411A2 (fr) | 2011-01-07 | 2012-07-12 | Dr Braja Sundar Pradhan | Méthode de préparation d'acide r-(-)-3-(carbamoylméthyl)-5-méthylhexanoïque et de ses intermédiaires |
| US10023885B2 (en) | 2012-11-07 | 2018-07-17 | Hikal Limited | Process for the preparation of pregabalin |
| JP6724283B2 (ja) | 2016-03-09 | 2020-07-15 | 国立大学法人 東京大学 | 光学活性の４−ニトロブタン酸エステル及びプレガバリンの製造方法 |
-
2021
- 2021-02-13 WO PCT/IN2021/050141 patent/WO2021161346A1/fr unknown
- 2021-02-13 JP JP2022548730A patent/JP7436689B2/ja active Active
- 2021-02-13 EP EP21753915.4A patent/EP4103168A4/fr active Pending
Non-Patent Citations (1)
| Title |
|---|
| H. ISHITANI, ET AL.: "Synthesis of (+/- )-pregabalin by utilising a three-step sequential-flow system with heterogeneous catalysts", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2017, no. 44, 10 October 2017 (2017-10-10), Wiley-VCH Verlag, Weinheim, DE, pages 6491 - 6494, XP072119280, ISSN: 1434-193X, DOI: 10.1002/ejoc.201700998 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4103168A1 (fr) | 2022-12-21 |
| JP7436689B2 (ja) | 2024-02-22 |
| JP2023513330A (ja) | 2023-03-30 |
| WO2021161346A1 (fr) | 2021-08-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL277146A (en) | Amino acid compounds and methods of use | |
| HUE063444T2 (hu) | Eljárás hosszú szénláncú aminosavak és kétbázisú savak elválasztására | |
| ZA201907864B (en) | Novel aspartokinase mutant and method for production of l-amino acid using same | |
| IL282026A (en) | Amino acid compounds and methods of use | |
| PL4036143T3 (pl) | Dwuczęściowa epoksydowa kompozycja elastomerowa zawierająca ester fosforanowy i sposób jej stosowania | |
| ZA202206109B (en) | Novel branched-chain amino acid aminotransferase variant and method for producing leucine using the same | |
| IL285262A (en) | A process for the preparation of polvestrant bearing boronic acid in position 3 | |
| WO2021100029A3 (fr) | Promédicaments de fulvestrant | |
| ZA202203557B (en) | Industrial process for the preparation of high purity estetrol | |
| IL290817A (en) | Methods for producing recombinant human arginase 1 and uses thereof | |
| IL290185A (en) | Crystalline forms of risdiplam and their preparation process | |
| EP4103168A4 (fr) | Procédé de préparation d'acides gamma-amino-butyriques et de leurs analogues | |
| IL289453A (en) | A process for the preparation of ridinilazole and crystalline forms thereof | |
| EP3927684A4 (fr) | Procédé d'acylation d'acides aminés et utilisations de produits d'acides aminés n-acyl | |
| EP3645504A4 (fr) | Procédé de séparation d'acides aminés à chaîne longue et d'acides dibasiques à chaîne longue | |
| EP3645499C0 (fr) | Procédé de séparation d'acides aminés à longue chaîne et d'acides dibasiques | |
| IL284574A (en) | Conotoxin analogs and peptides and uses for the treatment of pain and inflammatory conditions | |
| SG11202106368TA (en) | Method for reducing misincorporation of non-canonical branched-chain amino acids | |
| EP3947342A4 (fr) | Procédé de préparation de tapentadol et de ses analogues | |
| GB201902490D0 (en) | Novel compounds and pharmaceutical compositions thereof for the treatment of diseases | |
| IL310923A (en) | A method for the preparation of ω-amino carboxylic acids and their derivatives | |
| EP3894387A4 (fr) | Procédé d'acylation pour la préparation de peptide n-substitué | |
| HUP2100077A1 (hu) | Eljárás avapritinib és intermedierek elõállítására | |
| IL288801A (en) | Preparations containing acids do not have a branched chain | |
| IL311430A (en) | PROCESS FOR THE PREPARATION OF SAFINAMIDE |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20220801 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230626 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0031197000 Ipc: C07C0227200000 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20240321 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07C 251/38 20060101ALI20240315BHEP Ipc: C07C 249/08 20060101ALI20240315BHEP Ipc: C07C 233/47 20060101ALI20240315BHEP Ipc: C07C 231/00 20060101ALI20240315BHEP Ipc: C07C 69/716 20060101ALI20240315BHEP Ipc: C07C 67/347 20060101ALI20240315BHEP Ipc: C07C 229/08 20060101ALI20240315BHEP Ipc: C07C 227/20 20060101AFI20240315BHEP |