Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
  • A01N43/647—Triazoles; Hydrogenated triazoles
  • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Definitions

• the present invention relates to a method for controlling a phythopatogenic fungi selected from Septoria tritici (synonym Zymoseptoria tritici) and Puccinia spp. in cereals, comprising treating the plants, their seed or the soil with a fungicidally effective amount of a composition comprising
• mefentrifluconazole Owing to the basic character of its nitrogen atoms, mefentrifluconazole is capable of forming salts or adducts with inorganic or organic acids or with metal ions, in particular salts with inorganic acids. Mixtures of mefentrifluconazole are described in WO 2014/095994.
• Mefentrifluconazole (I) comprises chiral centers and is generally obtained in the form of race- mates.
• the R- and S-enantiomers of mefentrifluconazole (I) can be separated and isolated in pure form with methods known by the skilled person, e.g. by using chiral HPLC.
• mefentrifluconazole (I) can be used in form of
• Mefentrifluconazole (I) may be provided and used as (R)-enantiomer with an enantiomeric ex cess (e.e.) of at least 40%, for example, at least 50%, 60%, 70% or 80%, preferably at least 90%, more preferably at least 95%, yet more 25 preferably at least 98% and most preferably at least 99%. This applies to every composition detailed herein.
• the (R)-enantiomer of mefentriflu conazole has the chemical name:
• Mefentrifluconazole (I) may be further provided and used as (S)-enantiomer with an enantio meric excess (e.e.) of at least 40%, for example, at least 50%, 60%, 70% or 80%, preferably at least 90%, more preferably at least 95%, yet more preferably at least 98% and most preferably at least 99%. This applies to every composition detailed herein.
• the (S)-enantiomer of mefentri fluconazole has the chemical name:
• Agriculturally acceptable salts encompass especially the salts of those cations or the acid addi tion salts of those acids whose cations and anions, respectively, have no adverse effect on the fungicidal action of said compounds.
• Suitable cations are thus in particular the ions of the alkali metals, preferably sodium and potassium, of the alkaline earth metals, preferably calcium, mag nesium and barium, of the transition metals, preferably manganese, copper, zinc and iron, and also the ammonium ion which, if desired, may carry one to four Ci-C4-alkyl substituents and/or one phenyl or benzyl substituent, preferably diisopropylammonium, tetramethylammonium, tet- rabutylammonium, trimethylbenzylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(Ci-C4-alkyl)sulfonium, and
• Anions of useful acid addition salts are primarily chloride, bromide, fluoride, hydrogensulfate, sulfate, dihydrogenphosphate, hydrogenphosphate, phosphate, nitrate, bicarbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, and the anions of Ci-C4-alkanoic acids, preferably formate, acetate, propionate and butyrate. They can be formed by reacting such in ventive compound with an acid of the corresponding anion, preferably of hydrochloric acid, hy- drobromic acid, sulfuric acid, phosphoric acid or nitric acid.
• Septoria tritici ( Zymoseptoria tritici) is a species of filamentous fungus. It is a cereal plant patho gen causing septoria leaf blotch that is difficult to control especially due to resistance to multiple fungicides. The pathogen today causes one of the most feared diseases of wheat.
• Puccinia spp. e. g. brown or leaf rust caused P. triticina or P. recondita ; stripe or yellow rust caused by P. strihformis ; dwarf rust caused by P. hordei and stem or black rust caused P. graminis.
• the Puccinia spp cause rust epidemics causing significant loss of cereal yields. Control of Septoria leaf blotch and cereals rusts is becoming more and more difficult for farmers. In order to reduce crop losses and to obtain optimal crop yield proper pest management is required.
• compositions comprising mefentrifluconazole ans at least one compound (II) as defined herein shows an unexpected fungicidal action towards Septoria tritici and Puccinia spp.
• the unexpected fungicidal action is also observed against Septoria tritici being resistant against azole fungicides.
• the present invention relates to a method for controlling a phythopatogenic fungi selected from Septoria tritici and Puccinia spp. on cereals, comprising treating the plants, their seed or the soil with a fungicidally effective amount of a composition comprising
• the invention relates to a use of the compositions comprising mefentrifluconazole (I) and at least one compound (II) as described herein for controlling a phythopatogenic fungi selected from Septoria tritici and Puccinia spp. on cereal.
• the present invention relates to a method for controlling Septoria tritici. According to a specific embodiment, the present invention relates to a method for controlling Septoria tritici that is resistant to azole fungicides.
• the present invention relates to a method for controlling Puc cinia spp., in particular ⁇ triticina, P. recondite, P. strihformis, P. hordei and P. graminis.
• the compound (II) of the composition is selected from ben- zovindiflupyr (11-1 ), boscalid (II-2), dimoxystrobin (II-3), fenpicoxamid (II-4), fenpropimorph (II-5), florylpicoxamid (I I-6), fluindapyr (II-7), fluxapyroxad (I I-8), inpyrfluxam (II-9), ipflufenoquin (11-10), isoflucypram (11-1 1 ), isofetamid (11-12), kresoxym-methyl (11-13), quinofumelin (11-14), picar- butrazox (11-15), pydiflumetofen (11-16), pyraclostrobin (11-17), pyrapropoyne (11-18), 1 -(4,5- dimethylbenzimidazol-1 -yl)-4, 4, 6-trifluoro-3, 3-di
• the composition comprises mefentrifluconazole (I) and benzovindiflupyr (11-1 ).
• the composition comprises mefentrifluconazole (I) and boscalid (II-2).
• the composition comprises mefentrifluconazole (I) and dimoxystrobin (II-3).
• the composition comprises mefentrifluconazole (I) and fenpicoxamid (II-4).
• the composition comprises mefentrifluconazole (I) and fenpropimorph (II-5). According to another specific embodiment, the composition comprises mefentrifluconazole (I) and florylpicoxamid (II-6).
• the composition comprises mefentrifluconazole (I) and fluindapyr (II-7).
• the composition comprises mefentrifluconazole (I) and fluxapyroxad (II-8).
• the composition comprises mefentrifluconazole (I) and inpyrfluxam (II-9).
• the composition comprises mefentrifluconazole (I) and ipflufenoquin (11-10).
• the composition comprises mefentrifluconazole (I) and isoflucypram (11-1 1 ).
• the composition comprises mefentrifluconazole (I) and isofetamid (11-12).
• the composition comprises mefentrifluconazole (I) and kresoxym-methyl (11-13).
• the composition comprises mefentrifluconazole (I) and quinofumelin (11-14).
• the composition comprises mefentrifluconazole (I) and picarbutrazox (11-15).
• the composition comprises mefentrifluconazole (I) and pydiflumetofen (11-16).
• the composition comprises mefentrifluconazole (I) and pyraclostrobin (11-17).
• the composition comprises mefentrifluconazole (I) and pyrapropoyne (11-18).
• the composition comprises mefentrifluconazole (I) and 1 -(4, 5-dimethylbenzimidazol-1-yl)-4, 4, 6-trifluoro-3, 3-dimethyl-isoquinoline (11-19).
• the composition comprises mefentrifluconazole (I) and 6-chloro-1 -(4, 5-dimethylbenzimidazol-1-yl)-4,4-difluoro-3, 3-dimethyl-isoquinoline (II-20).
• the composition comprises mefentrifluconazole (I) and 1 -(4, 5-dimethylbenzimidazol-1-yl)-4,4-difluoro-3, 3-dimethyl-isoquinoline (11-21 ).
• the composition comprises mefentrifluconazole (I) and 4,4-difluoro-3,3-dimethyl-1-(4-methylbenzimidazol-1-yl)isoquinoline (II-22).
• the composition comprises mefentrifluconazole (I) and 1-(6-chloro-7-methyl-pyrazolo[1 ,5-a]pyridin-3-yl)-4,4-difluoro-3, 3-dimethyl-isoquinoline (II-
• the composition comprises mefentrifluconazole (I) and 4, 4-difluoro-1-(6-fluoro-7-methyl-pyrazolo[1 ,5-a]pyridin-3-yl)-3, 3-dimethyl-isoquinoline (II-
• the composition comprises mefentrifluconazole (I) and 4,4-difluoro-3,3-dimethyl-1-(6-methylpyrazolo[1 ,5-a]pyridin-3-yl)isoquinoline (II-25).
• the composition comprises mefentrifluconazole (I) and 1 -(6, 7-dimethylpyrazolo[1 ,5-a]pyridin-3-yl)-4,4-difluoro-3, 3-dimethyl-isoquinoline (II-26).
• the composition comprises mefentrifluconazole (I) and 1 -(7, 8-dimethylimidazo[1 ,2-a]pyridin-3-yl)-4,4-difluoro-3, 3-dimethyl-isoquinoline (II-27).
• the composition comprises mefentrifluconazole (I) and one compound (II) as the only active ingredients of the composition.
• the composition comprises mefentrifluconazole (I) and two compounds (II) differ ent from each other as the only active ingredients of the composition.
• the weight ratio of compound I and compound II is usually from 500:1 to 1 :500, preferably from 100:1 to 1 :100, more preferably from 50:1 to 1 :50, even more preferably from 20:1 to 1 :20, most preferably from 10:1 to 1 :10.
• the ratios can also be from 1 :5 to 5:1 , or 1 :1.
• the compound (I) and compound (II) can be applied simultaneously, that is jointly or separately, or in succession. According to one embodiment, the compound (I) and compound (II) are ap plied simultaneously. According to another embodiment, compound (I) and compound (II) are applied in succession.
• the method comprises treating the cereal plants.
• the method comprises treating cereal seeds.
• the method comprises treating the soil.
• cereal plants as used herein comprises wheat, triticale, barley and rye.
• the cereal is wheat or triticale.
• the wheat or triticale plants are treated, preferably the wheat plants are treated.
• the wheat or triticale seeds are treated, preferably the wheat seeds are treated.
• the cereal is barley. According to one specific embodiment the barley plants are treated. According to another specific embodiment the barley seeds are treated.
• the cereal is rye.
• the rye plants are treated.
• the rye seeds are treated.
• the present invention relates to a method for controlling Septoria tritici on wheat, comprising treating the plants, their seed or the soil with a fungicidally effective amount of a composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein.
• the method comprises treating the wheat plants.
• the method comprises treating wheat seeds. Treating the plants, their seed or the soil in the method according to present invention may be carried out in spray application, in seed treatment, in drip and drench applications, in-furrow applications, on-seed application and overall soil incorporation, chemigation, i.e. by addition of the active ingredients to the irrigation water, and in hydroponic/mineral systems.
• Table A Methods to control Septoria tritici. Each line of lines A-1 to A-324 corresponds to one particular embodiment of the invention
• Methods B-1 to B-324 differing from the methods A1 to A-324 of the Table A only in that in each case the pathogen Septoria tritici is replaced by Puccinia triticina.
• Methods C-1 to C-324 differing from the methods A1 to A-324 of the Table A only in that in each case the pathogen Septoria tritici is replaced by Puccinia recondite.
• Table D Methods to control Puccinia striiformis.
• Methods D-1 to D-324 differing from the methods A1 to A-324 of the Table A only in that in each case the pathogen Septoria tritici is replaced by Puccinia striiformis.
• Methods E-1 to E-324 differing from the methods A1 to A-324 of the Table A only in that in each case the pathogen Septoria tritici is replaced by Puccinia hordei.
• Methods F-1 to F-324 differing from the methods A1 to A-324 of the Table A only in that in each case the pathogen Septoria tritici is replaced by Puccinia graminis.
• plant propagation material is to be understood to denote all the generative parts of the plant in particular seeds
• Plants and as well as the propagation material of said plants, which can be treated with fungi- cidally effective amount of a composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein include all genetically modified plants or transgenic plants, e.g. crops which tolerate the action of herbicides or fungicides or insecticides owing to breeding, including genetic engineering methods, or plants which have modified characteristics in compar ison with existing plants, which can be generated for example by traditional breeding methods and/or the generation of mutants, or by recombinant procedures.
• mixtures according to the present invention can be applied (as seed treatment, spray treatment, in furrow or by any other means) also to plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf.
• Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant.
• Such genetic modi fications also include but are not limited to targeted post-transitional modification of protein(s), oligo- or polypeptides e. g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties.
• a composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein can be converted into the customary formu lations, for example solutions, emulsions, suspensions, dusts, powders, pastes and granules.
• the use form depends on the particular intended purpose; in each case, it should ensure a fine and even distribution of the mixtures according to the present invention.
• the formulations are prepared in a known manner (cf. US 3,060,084, EP-A 707 445 (for liquid concentrates), Brown ing:’Agglomeration”, Chemical Engineering, Dec.
• the agrochemical formulations may also comprise auxiliaries which are customary in agro chemical formulations.
• auxiliaries used depend on the particular application form and active substance, respectively.
• auxiliaries are solvents, solid carriers, dispersants or emulsifiers (such as further solubilizers, protective colloids, surfactants and adhesion agents), organic and inorganic thickeners, bactericides, anti-freezing agents, anti-foaming agents, if appropriate colorants and tackifiers or binders (e. g. for seed treatment formulations).
• Suitable solvents are water, organic solvents such as mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e. g.
• Solid carriers are mineral earths such as silicates, silica gels, talc, kaolins, limestone, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, calcium sulfate, magnesi-um sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as ce real meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid car riers.
• mineral earths such as silicates, silica gels, talc, kaolins, limestone, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, calcium sulfate, magnesi-um sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammoni
• Suitable surfactants are alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, such as ligninsoulfonic acid (Borresperse® types, Borregard, Norway) phenolsulfonic acid, naphthalenesulfonic acid (Mor- wet® types, Akzo Nobel, U.S.A.), dibutylnaphthalene-sulfonic acid (Nekal® types, BASF, Ger many), and fatty acids, alkylsulfonates, alkyl-arylsulfonates, alkyl sulfates, laurylether sulfates, fatty alcohol sulfates, and sulfated hexa-, hepta- and octadecanolates, sulfated fatty alcohol glycol ethers, furthermore conden
• methylcellulose g. methylcellulose
• hydrophobically modified starches polyvinyl alcohols (Mowiol® types, Clariant, Switzerland), polycarboxylates (Sokolan® types, BASF, Germany), polyalkoxylates, polyvinylamines (Lupasol® types, BASF, Germany), polyvinylpyrrolidone and the copolymers therof.
• thickeners i. e. compounds that impart a modified flowability to formula-tions, i. e. high viscosity under static conditions and low viscosity during agitation
• thickeners are polysaccharides and organic and inorganic clays such as Xanthan gum (Kelzan®, CP Kelco, U.S.A.), Rhodopol® 23 (Rhodia, France), Veegum® (R.T. Vanderbilt, U.S.A.) or Attaclay® (Engelhard Corp., NJ, USA).
• Bactericides may be added for preservation and stabilization of the formulation.
• suitable bactericides are those based on dichlorophene and benzylalcohol hemi formal (Proxel® from ICI or Acticide® RS from Thor Chemie and Kathon® MK from Rohm & Haas) and isothia- zolinone derivatives such as alkylisothiazolinones and benzisothiazolinones (Acticide® MBS from Thor Chemie).
• Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glyc erin.
• anti-foaming agents examples include silicone emulsions (such as e. g. Silikon® SRE, Wacker, Germany or Rhodorsil®, Rhodia, France), long chain alcohols, fatty acids, salts of fatty acids, fluoroorganic compounds and mixtures thereof.
• Suitable colorants are pigments of low water solubility and water-soluble dyes. Examples are rhodamin B, C. I. pigment red 112, C. I. solvent red 1 , pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48:1 , pigment red 57:1 , pigment red 53:1 , pig ment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108.
• tackifiers or binders examples include polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols and cellulose ethers (Tylose®, Shin-Etsu, Japan).
• Powders, materials for spreading and dusts can be prepared by mixing or conco-mitantly grind ing composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein and, if appropriate, further active substances, with at least one solid carrier.
• Granules e. g. coated granules, impregnated granules and homogeneous granules, can be prepared by binding composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein to solid carriers.
• solid carriers are mineral earths such as silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, dia- tomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic ma terials, fertilizers, such as, e.
• ammonium sulfate ammonium phosphate, ammonium nitrate, ureas
• products of vegetable origin such as cereal meal, tree bark meal, wood meal and nut-shell meal, cellulose powders and other solid carriers.
• formulation types are suspensions (SC, OD, FS), emulsifiable concentrates (EC), emulsions (EW, EO, ES), pastes, pastilles, wettable powders or dusts (WP, SP, SS, WS, DP, DS) or granules (GR, FG, GG, MG), which can be water-soluble or wettable, as well as gel for mulations for the treatment of plant propagation materials such as seeds (GF), herein further below exemplified in detail:
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are dissolved in 90 parts by weight of water or in a water-soluble sol vent.
• wetting agents or other auxiliaries are added.
• the active substance dis solves upon dilution with water. In this way, a formulation having a content of 10% by weight of active substance is obtained.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are dissolved in 70 parts by weight of cyclohexanone with addition of 10 parts by weight of a dispersant, e. g. poly-vinylpyrrolidone. Dilution with water gives a disper sion.
• a dispersant e. g. poly-vinylpyrrolidone. Dilution with water gives a disper sion.
• the active substance content is 20% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are dissolved in 75 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). Dilution with water gives an emulsion.
• the composition has an active substance content of 15% by weight.
• Emulsions (EW, EO, ES)
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are dissolved in 35 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight).
• This mix ture is introduced into 30 parts by weight of water by means of an emulsifying machine (Ultra- turrax) and made into a ho-mogeneous emulsion. Dilution with water gives an emulsion.
• the composition has an active substance content of 25% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are comminuted with addition of 10 parts by weight of dispersants and wetting agents and 70 parts by weight of water or an organic solvent to give a fine active substance sus-pension. Dilution with water gives a stable suspension of the active substance.
• the active substance content in the composition is 20% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are ground finely with addi-tion of 50 parts by weight of dispersants and wetting agents and prepared as water-dispersible or water-soluble granules by means of tech nical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.
• the composition has an active substance content of 50% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are ground in a rotor-stator mill with addition of 25 parts by weight of dispersants, wetting agents and silica gel. Dilution with water gives a stable dispersion or solu tion of the active substance.
• the active substance content of the composition is 75% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are comminuted with addition of 10 parts by weight of dispersants, 1 part by weight of a gelling agent wetters and 70 parts by weight of wa ter or of an organic solvent to give a fine suspension of the active substance.
• dispersants 1 part by weight of a gelling agent wetters and 70 parts by weight of wa ter or of an organic solvent to give a fine suspension of the active substance.
• a gelling agent wetters 1 part by weight of a gelling agent wetters and 70 parts by weight of wa ter or of an organic solvent to give a fine suspension of the active substance.
• Dilution with water gives a stable suspension of the active substance, whereby a composition with 20% (w/w) of active substance is obtained.
• Dustable powders (DP, DS)
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are ground finely and mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dustable compo-sition having an active substance content of 5% by weight.
• composition comprising mefentrifluconazole (I) and at least one com pound (II) as described herein is ground finely and associ-ated with 99.5 parts by weight of car riers.
• Current methods are extrusion, spray-drying or the fluidized bed. This gives granules to be applied undiluted having an active sub-stance content of 0.5% by weight.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are dissolved in 90 parts by weight of an organic solvent, e. g. xylene.
• an organic solvent e. g. xylene.
• the agrochemical formulations generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, most preferably between 0.5 and 90%, by weight of active substances.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein can be used as such or in the form of their compositions, e. g. in the form of directly sprayable solutions, powders, suspensions, dispersions, emulsions, oil dispersions, pastes, dustable products, materials for spreading, or granules, by means of spraying, atomizing, dust ing, spreading, brushing, immersing or pouring.
• Aqueous application forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water.
• emulsions, pastes or oil dispersions the substances, as such or dissolved in an oil or solvent, can be homogenized in water by means of a wetter, tackifier, dispersant or emulsifier.
• the active substance concentrations in the ready-to-use preparations can be varied within rela tively wide ranges. In general, they are from 0.0001 to 10%, preferably from 0.001 to 1 % by weight of composition comprising mefentrifluconazole (I) and at least one compound (II) as de scribed herein.
• compositions comprising mefentrifluconazole (I) and at least one compound (II) as described herein may also be used successfully in the ultra-low-volume process (ULV), it being possible to apply compositions comprising over 95% by weight of active substance, or even to apply the active substance without addi-tives.
• UUV ultra-low-volume process
• oils, wetters, adjuvants, herbicides, fungicides, other pesticides, or bactericides may be added to the active compounds present in the composition comprising mefentriflucona zole (I) and at least one compound (II) as described herein, if appropriate not until immediately prior to use (tank mix).
• These agents can be admixed with composition comprising mefentriflu conazole (I) and at least one compound (II) as described herein in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.
• compositions of this invention may also contain fertilizers such as ammonium nitrate, urea, pot ash, and superphosphate, phytotoxicants and plant growth regulators and safeners. These may be used sequentially or in combination with the above-described compositions, if appropriate also added only immediately prior to use (tank mix). For example, the plant(s) may be sprayed with a composition of this invention either before or after being treated with the fertilizers.
• fertilizers such as ammonium nitrate, urea, pot ash, and superphosphate, phytotoxicants and plant growth regulators and safeners.
• compositions are applied by treating the fungi or the plants, plant propagation materials (pref erably seeds), materials or soil to be protected from fungal attack with a pesticidally effective amount of composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein.
• the application can be carried out both before and after the infection of the materials, plants or plant propagation materials (preferably seeds) by the pests.
• pesticidally effective amount means the amount of composition comprising mefen trifluconazole (I) and at least one compound (II) as described herein or of compositions compris ing composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occur rence and activity of the target organism.
• the pesticidally effective amount can vary.
• a pesti cidally effective amount will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
• compositions comprising composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein, it is preferred to employ the pure active compound, to which optionally further active compounds against pests, such as insecticides, herbicides, fungicides or else herbicidal or growth-regulating active compounds or fertilizers can be added as further active components according to need.
• pests such as insecticides, herbicides, fungicides or else herbicidal or growth-regulating active compounds or fertilizers can be added as further active components according to need.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein is employed by treating the fungi or the plants or soil to be protected from pes- ticidal attack via foliar application with a pesticidally effective amount of composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein.
• the ap plication can be carried out both before and after the infection of the plants by the pests.
• the application rates of composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are from 0,1 g/ha to 10000 g/ha, preferably 2 g/ha to 2500 g/ha, more preferably from 5 to 1000 g/ha, most preferably from 10 to 750 g/ha, in particular from 20 to 700 g/ha.
• composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein are used for the protection of the seed and the seedlings' roots and shoots, preferably the seeds as set forth above.
• compositions which are especially useful for seed treatment are e.g.:
• a Soluble concentrates (SL, LS)
• compositions can be applied to plant propagation materials, particularly seeds, diluted or undiluted.
• the compositions in question give, after two-to-tenfold dilution, active substance con centrations of from 0.01 to 60% by weight, prefer-ably from 0.1 to 40% by weight, in the ready- to-use preparations.
• Application can be carried out before or during sowing.
• Methods for apply ing or treating agrochemical compounds and compositions thereof, respectively, on to plant propagation material, especially seeds are known in the art, and include dressing, coating, pel leting, dusting and soaking application methods of the propagation material (and also in furrow treatment).
• the compounds or the compositions thereof, respective ly are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dusting.
• the application rates of the in- ventive mixture are generally for the formulated product (which usually comprises from 10 to 750 g/l of the active(s)) .
• the invention also relates to the propagation products of plants, and especially the seed com prising, that is, coated with and/or containing, a mixture as defined above or a composition con taining the mixture of two or more active ingredients or a mixture of two or more compositions each providing one of the active ingredients.
• the plant propagation material (preferably seed) comprises composition comprising mefentrifluconazole (I) and at least one compound (II) as described herein in an amount of from 0.1 g to 10 kg per 100 kg of plant propagation material (preferably seed), preferably 0.1 g to 1 kg per 100 kg of plant propagation mate rial (preferably seed).
• the spray solutions were prepared in several steps:
• the stock solution was prepared: a mixture of acetone and/or dimethylsulfoxide and the wetting agent/emulsifier Wettol, which is based on ethoxylated alkylphenoles, in a relation (volume) sol vent-emulsifier of 99 to 1 was added to the initial weight of the compound to give a total of 5 ml. Water was then added to total volume of 100 ml.
• Wettol which is based on ethoxylated alkylphenoles
• This stock solution was diluted with the described solvent-emulsifier-water mixture to the given concentration.
• Leaves of pot-grown wheat seedling were inoculated with an aqueous spore suspension of Sep toria tritici. Then the trial plants were immediately transferred to a humid chamber at 18-22°C and a relative humidity close to 100 %. After 4 days the plants were transferred to a chamber with 18-22°C and a relative humidity close to 70 %. Seven days after inoculation the plants were sprayed to run-off with an aqueous suspension of the active compound or their mixture, prepared as described. Then the plants were transferred back to the chamber with 18-22°C and a relative humidity close to 70 %. After 4 weeks the extent of fungal attack on the leaves was visually assessed as % diseased leaf area.
• the first two developed leaves of pot-grown wheat seedling were dusted with spores of Puccin ia recondita. To ensure the success the artificial inoculation, the plants were transferred to a humid chamber without light and a relative humidity of 95 to 99 % and 20 to 24°C for 24 h. The next day the plants were cultivated for 2 days in a greenhouse chamber at 20-24°C and a rela tive humidity between 65 and 70 %. Then the plants were sprayed to run-off with an aqueous suspension, containing the concentration of active ingredient or their mixture as described be low. The plants could air-dry. Then the trial plants were cultivated for 8 days in a greenhouse chamber at 20-24°C and a relative humidity between 65 and 70 %. The extent of fungal attack on the leaves was visually assessed as % diseased leaf area.
• the first two developed leaves of pot-grown wheat seedling were sprayed to run-off with an aqueous suspension, containing the concentration of active ingredient or their mixture as de scribed below. Seven days later the plants were inoculated with spores of Puccinia recondita.
• the plants were transferred to a humid chamber without light and a relative humidity of 95 to 99 % and 20 to 24°C for 24 h. Then the trial plants were cultivated for 5 days in a greenhouse chamber at 20-24°C and a relative humidity between 65 and 70 %. The extent of fungal attack on the leaves was visually assessed as % diseased leaf area.
• the measured parameters were compared to the growth of the active compound-free control variant (100%) and the fungus-free and active compound-free blank value to determine the rela tive growth in % of the pathogens in the respective active compounds. These percentages were converted into efficacies.
• An efficacy of 0 means that the growth level of the pathogens corre sponds to that of the untreated control; an efficacy of 100 means that the pathogens were not growing.
• the trial was conducted under field conditions. Seeds of wheat were planted and grown under standard conditions with adequate supply of water and nutrients. At the growth stage of 37-39, an application of the compounds was made once. No other compounds were applied for patho gen control. Infection with pathogens occurred naturally. The disease incidences were evaluat ed 42 days after the first application ( Septtr ).
• the diseases were converted into efficacies.
• An efficacy of 0 means that the infection level of the treated plants corresponds to that of the untreated control plants; an efficacy of 100 means that the treated plants were not infected.
• the expected efficacies of active compound mixtures were determined using Colby's formula [R.S. Colby,“Calculating synergistic and antagonistic responses of herbicide combinations", Weeds 15, 20-22 (1967)] and compared with the observed efficacies. The dosages used, and the obtained results are shown below:

Landscapes

• Life Sciences & Earth Sciences (AREA)
• Agronomy & Crop Science (AREA)
• Pest Control & Pesticides (AREA)
• Plant Pathology (AREA)
• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Dentistry (AREA)
• General Health & Medical Sciences (AREA)
• Wood Science & Technology (AREA)
• Zoology (AREA)
• Environmental Sciences (AREA)
• Agricultural Chemicals And Associated Chemicals (AREA)
• Nitrogen Condensed Heterocyclic Rings (AREA)

Applications Claiming Priority (2)

Publications (1)

Family

ID=64664879

Family Applications (1)

Country Status (3)

Families Citing this family (3)

Family Cites Families (19)

• 2019
  • 2019-12-02 EA EA202191560A patent/EA202191560A1/ru unknown
  • 2019-12-02 WO PCT/EP2019/083333 patent/WO2020120204A2/en unknown
  • 2019-12-02 EP EP19816256.2A patent/EP3893643A2/de active Pending

Also Published As

Similar Documents

Legal Events