EP3891224A4 - Chromophores ir à base de polyméthine hétérocyclyle - Google Patents

Chromophores ir à base de polyméthine hétérocyclyle Download PDF

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Publication number
EP3891224A4
EP3891224A4 EP19892945.7A EP19892945A EP3891224A4 EP 3891224 A4 EP3891224 A4 EP 3891224A4 EP 19892945 A EP19892945 A EP 19892945A EP 3891224 A4 EP3891224 A4 EP 3891224A4
Authority
EP
European Patent Office
Prior art keywords
polymethine
chromophores
heterocyclyl
heterocyclyl polymethine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19892945.7A
Other languages
German (de)
English (en)
Other versions
EP3891224A1 (fr
Inventor
Ellen M. SLETTEN
Emily D. COSCO
Anthony SPEARMAN
Monica PENGSHUNG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of EP3891224A1 publication Critical patent/EP3891224A1/fr
Publication of EP3891224A4 publication Critical patent/EP3891224A4/fr
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/08Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0008Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
    • C09B23/0016Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being a halogen atom
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/04Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups one >CH- group, e.g. cyanines, isocyanines, pseudocyanines
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19892945.7A 2018-12-05 2019-12-05 Chromophores ir à base de polyméthine hétérocyclyle Pending EP3891224A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862775788P 2018-12-05 2018-12-05
PCT/US2019/064790 WO2020118116A1 (fr) 2018-12-05 2019-12-05 Chromophores ir à base de polyméthine hétérocyclyle

Publications (2)

Publication Number Publication Date
EP3891224A1 EP3891224A1 (fr) 2021-10-13
EP3891224A4 true EP3891224A4 (fr) 2023-01-18

Family

ID=70974004

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19892945.7A Pending EP3891224A4 (fr) 2018-12-05 2019-12-05 Chromophores ir à base de polyméthine hétérocyclyle

Country Status (2)

Country Link
EP (1) EP3891224A4 (fr)
WO (1) WO2020118116A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018226720A1 (fr) 2017-06-05 2018-12-13 The Regents Of The University Of California Chromophores ir à base de polyméthine hétérocyclyle
CN115996920A (zh) * 2020-06-25 2023-04-21 光波逻辑有限公司 包含类金刚烷基团的非线性光学发色团
WO2022024942A1 (fr) * 2020-07-29 2022-02-03 Agc株式会社 Filtre optique
CN112409590B (zh) * 2020-10-21 2021-10-26 复旦大学 用于近红外区第二窗口生物成像的有机纳米组装体及其制备方法和应用
CN112225721B (zh) * 2020-10-21 2021-09-17 复旦大学 酸响应的近红外溶酶体有机小分子荧光探针及其制备方法和应用
CN114478587B (zh) * 2021-12-29 2023-07-28 南京邮电大学 一种近红外二区染料、纳米粒子及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018187295A1 (fr) * 2017-04-03 2018-10-11 Massachusetts Institute Of Technology Colorants de polyméthine à infrarouge proche et à ondes courtes
WO2018226720A1 (fr) * 2017-06-05 2018-12-13 The Regents Of The University Of California Chromophores ir à base de polyméthine hétérocyclyle
WO2020245446A1 (fr) * 2019-06-07 2020-12-10 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Système et procédé d'imagerie par fluorescence infrarouge à ondes courtes multicolore en temps réel
WO2020245447A1 (fr) * 2019-06-07 2020-12-10 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Procédé et dispositif d'imagerie de protéines fluorescentes dans l'infrarouge proche et à ondes courtes

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DE69112852T2 (de) * 1990-01-16 1996-05-15 Showa Denko Kk Polymerisationsinitiator verwendbar in der Nähe von Infrarot.
US5262549A (en) * 1991-05-30 1993-11-16 Polaroid Corporation Benzpyrylium dyes, and processes for their preparation and use
JP3341141B2 (ja) * 1995-11-21 2002-11-05 コニカ株式会社 ハロゲン化銀写真感光材料
DE19845642A1 (de) * 1998-10-05 2000-04-06 Agfa Gevaert Ag Cyaninfarbstoffe
JP2003176270A (ja) * 2001-12-12 2003-06-24 Sharp Corp エナミン化合物、それを用いた電子写真感光体および画像形成装置
US9297807B2 (en) * 2006-02-10 2016-03-29 Agilent Technologies, Inc. Protein analysis using a polymethine marker dye
US10264974B2 (en) * 2012-11-20 2019-04-23 The Board Of Trustees Of The Leland Stanford Junior University High resolution imaging using near-infrared-II fluorescence
WO2016081813A1 (fr) * 2014-11-20 2016-05-26 The Research Foundation For The State University Of New York University At Buffalo Colorants à base de chalcogénopyrylium, compositions les comprenant, nanoparticules composites les comprenant, procédés de fabrication et d'utilisation associés
JP2016113503A (ja) * 2014-12-12 2016-06-23 日本化薬株式会社 トリフルオロメチル化シアニン化合物及び該化合物を含む近赤外線カットフィルタ
EP3334463A1 (fr) * 2015-08-11 2018-06-20 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Conjugués d'acides nucléiques peptidiques émettant un rayonnement et leurs utilisations pour le diagnostic, l'imagerie et le traitement de maladies, affections et troubles
US9862682B2 (en) * 2016-01-08 2018-01-09 BroadPharm Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018187295A1 (fr) * 2017-04-03 2018-10-11 Massachusetts Institute Of Technology Colorants de polyméthine à infrarouge proche et à ondes courtes
WO2018226720A1 (fr) * 2017-06-05 2018-12-13 The Regents Of The University Of California Chromophores ir à base de polyméthine hétérocyclyle
WO2020245446A1 (fr) * 2019-06-07 2020-12-10 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Système et procédé d'imagerie par fluorescence infrarouge à ondes courtes multicolore en temps réel
WO2020245447A1 (fr) * 2019-06-07 2020-12-10 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Procédé et dispositif d'imagerie de protéines fluorescentes dans l'infrarouge proche et à ondes courtes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020118116A1 *

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Publication number Publication date
EP3891224A1 (fr) 2021-10-13
WO2020118116A1 (fr) 2020-06-11

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