EP3801413A1 - Dispositif mobile à interface pour le traitement d'un prurit - Google Patents

Dispositif mobile à interface pour le traitement d'un prurit

Info

Publication number
EP3801413A1
EP3801413A1 EP19729518.1A EP19729518A EP3801413A1 EP 3801413 A1 EP3801413 A1 EP 3801413A1 EP 19729518 A EP19729518 A EP 19729518A EP 3801413 A1 EP3801413 A1 EP 3801413A1
Authority
EP
European Patent Office
Prior art keywords
treatment
temperature
mobile device
interface
preferred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19729518.1A
Other languages
German (de)
English (en)
Inventor
Daniel BÜNGER VON WURMB
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dermapharm AG
Original Assignee
Dermapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermapharm AG filed Critical Dermapharm AG
Publication of EP3801413A1 publication Critical patent/EP3801413A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/30—Services specially adapted for particular environments, situations or purposes
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/70—Services for machine-to-machine communication [M2M] or machine type communication [MTC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A61F2007/0052—Body part for treatment of skin or hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0077—Details of power supply
    • A61F2007/0078—Details of power supply with a battery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0077—Details of power supply
    • A61F2007/0078—Details of power supply with a battery
    • A61F2007/008—Details of power supply with a battery with a separate, portable battery pack
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0093—Heating or cooling appliances for medical or therapeutic treatment of the human body programmed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0094—Heating or cooling appliances for medical or therapeutic treatment of the human body using a remote control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
    • A61F2007/0096—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator with a thermometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A61F2007/0284—Treatment of stings or bites

Definitions

  • the invention in a first aspect, relates to a device for hyperthermic treatment of itching comprising at least one treatment surface which can be heated by heating at least one heating element to a treatment temperature of 40 ° C to 65 ° C and is controllable by a control device, the device at least one Interface and is configured for a power supply of the device by a mobile device and / or for data exchange with a mobile device and / or for controlling by a
  • the invention relates to a system of device and mobile device, wherein the device is configured for power supply by the mobile device and / or for data exchange with the mobile device and / or for control by the mobile device via an interface.
  • Itching is a subjectively unpleasant, on the skin or mucosa related sensory perception. It may be local or affect the whole body.
  • Histamine (mosquito bite), Apamin (bee sting), caused by allergic immune reaction, pressure or friction or by heat or sunlight, wheals, urticaria and other itching skin reactions. From a medical point of view, the causes or underlying diseases that cause itching span a broad spectrum of dermatological and internal medicine
  • Glucocorticoids for treatment of wasps or bee stings, the puncture sites are also treated with sal ammoniacal spirit, which, however, only leads to a short-term relief of the itching and also reduces the swelling only to a small extent.
  • the applications of hyperthermic treatment continue to extend to herpes.
  • a device for the treatment of herpes diseases is known.
  • the device comprises a heating plate with a preferred size of 20 mm 2 , which is heated to 49 ° C - 53 ° C for a treatment time of preferably 10 - 15 sec.
  • the heating plate contacts the affected area of the skin of the lips, for example the reddened area or the position at which bubbles have already formed.
  • the heat application leads on the one hand to a containment of the propagation of the causative pathogens by a neutralizing effect on the herpes simplex viruses.
  • the device is thus characterized by a reduction in the symptoms of
  • Herpes disease such as Burning, the appearance of swelling, redness or itching.
  • Hyperthermal treatment of insect bites known to provide a treatment temperature of 50 ° C.
  • This device has the disadvantage that at this temperature, processes that relieve the itching are not or not properly triggered.
  • essential processes that help to alleviate the symptoms of insect bites, herpes, jellyfish or other itching diseases are sometimes only in a temperature range between 50 ° C and 56 ° C, especially between 50 ° C and 53 ° C. , activated.
  • the devices also have disadvantages.
  • no device is known in the prior art, which combines the benefits of modern mobile devices, such as high computing power, networking, but also the ability to serve as an energy source for physical application, with a device for the treatment of pruritus.
  • Mobile devices, especially smartphones are today not only used for their original purpose, such as making a phone call. Rather, it is commonplace today to combine as many applications as possible in the small portable devices. So today's smartphones are also used as cameras, players, readers, for computer games, as a navigation device and much more.
  • a stimulator for alleviating pain in a premenstrual syndrome (PMS) by means of so-called stimulus pods is proposed, wherein the stimulus pods can be controlled by remote control in the form of a computer or mobile device.
  • WO 2015 / 109397A1 describes a device for the treatment of boils caused by Staphylococcus bacteria with the aid of a heat or cooling pad which can apply ointments or therapeutic solutions. Part of a wireless software control via mobile devices.
  • US9795502 B1 discloses a heat mask for the treatment of colds and inflammations of the paranasal sinuses, which can be remotely controlled by means of a smart phone or tablet.
  • WO 2018/024753 A1 describes a device for the cosmetic treatment of the eye region with alternating temperature application.
  • the control can also be supported by a touch display.
  • the US 2017/0273821 A1 relates to heat pads for the cosmetic stimulation of the skin or hair, whereby a control via a USB interface by means of a mobile device can be provided.
  • the desired treatment temperature may be exceeded in exceptional cases.
  • US 2007/0049998 A1 discloses a device for hyperthermic treatment of
  • the device is based on the therapeutic idea to destroy germs by heat application and kill irritants of the skin.
  • the treatment periods and / or temperatures required for this purpose are not suitable for sustainably alleviating itching by targeted stimulation of specific receptors and the modification of the immune system. Temperatures below 42 ° C are in turn unsuitable to achieve therapeutic effects beyond a sensation of heat.
  • Fuse triggers already at an electrical current above a threshold value, which could cause too high a temperature if it flows too long.
  • both the temperature range and duration of the heating process are certainly relevant to a variety of applications, but unsuitable for sustainably relieving pruritus through heat application.
  • An object of the invention was to eliminate the disadvantages of the prior art.
  • the invention relates to a device for hyperthermic treatment of pruritus, comprising at least one treatment surface which is heatable by heating at least one heating element to a treatment temperature of 40 ° C to 65 ° C and controllable by a control device, characterized in that the device has at least one interface and is configured for a power supply of the device by a mobile device and / or for data exchange with a mobile device and / or for
  • the invention relates to a system of device and mobile device, wherein the device is configured for power supply by the mobile device and / or for data exchange with the mobile device and / or for control by the mobile device via an interface.
  • the invention in a first aspect, relates to a device for hyperthermic treatment of itching comprising at least one treatment surface which is heatable by heating at least one heating element to a treatment temperature of 40 ° C to 65 ° C and controllable by a control device, characterized in that the Device has at least one interface and is configured for a power supply of the device by a mobile device and / or for data exchange with a mobile device and / or to
  • the device according to the invention is preferably applied to the affected skin. After contacting the skin area with the treatment area provides a
  • Control device that a regulation of the invention of the temperature of
  • Treatment surface is done.
  • the treatment temperature is preferably always those
  • Treatment surface this led first in a heating phase to a treatment temperature between 40 ° C and 65 ° C. It is preferred that the heating phase does not require a longer period of time. Preferably, the heating phase should not be more than 10 seconds, more preferably not more than 3 seconds.
  • the temperature of the treatment surface is preferably maintained at the predetermined treatment temperature.
  • the Treatment temperature preferably corresponds to a constant temperature, which lies in the stated range between 40 ° C and 65 ° C.
  • This treatment temperature is preferably kept constant during the treatment phase. However, it may also be preferred that the treatment temperature is not kept constant.
  • the treatment surface can also be led in a temperature ramp to a maximum temperature in the range of the treatment temperature between 40 ° C and 65 ° C. Thereafter, it may be preferred that the temperature be briefly lowered below the range of the treatment temperature. Subsequently, the temperature can rise again, so that a temporal temperature profile in the form of a ramp arises.
  • this preferred variant has proven to be advantageous over maintaining a constant itchiness in skin diseases leading to itching
  • Treatment temperature proved.
  • it can be an advantage to
  • the treatment phase preferably designates the period during which the temperature is in the range of the treatment temperature from 40 ° C to 65 ° C. Preferably takes the
  • Treatment phase 2 to 20 sec more preferably, the treatment phase lasts between 2 sec and 12 sec, most preferably between 3 sec and 6 sec. It is particularly preferred that the treatment phase denotes a continuous period. But it can also be that the treatment phase is interrupted by passing the temperature, which has the form of a ramp in time, briefly. In this case, the period of the treatment phase is preferably understood as the time during which the temperature of the treatment surface is in the range of the treatment temperature of 40 ° C. to 65 ° C.
  • the treatment phase is not defined in advance but is adjusted individually, for example by the control device, e.g. B. in conjunction with other externally provided parameters. It may also be preferred that the treatment phase continues as long as a user actuates a control button to maintain the treatment.
  • the treatment phase may be synonymous with the following
  • Treatment duration can be used.
  • the treatment surface preferably designates that surface of the device which is heated to the treatment temperature during the treatment and is in direct thermal contact with the skin area.
  • the treatment area can be a continuous area. It may also be preferred that the treatment surface consists of several non-contiguous partial surfaces.
  • the size of the treatment area preferably depends on the disease and the size of the skin affected by the symptoms of itching disease. In the case of insect bites, the size of the treatment area is between 10 mm 2 and 100 mm 2 , more preferably between 20 mm 2 and 60 mm 2 . In the treatment of herpes, the treatment area is preferably between 10 mm 2 and 80 mm 2 , more preferably between 20 mm 2 and 50 mm 2 .
  • the treatment surface is circular for these smaller areas of the skin. Due to the chosen sizes and geometries of the treatment area, one of the causes can be optimal adapted treatment, which optimizes efficiency and well-being and thus contributes to a more sustainable treatment success.
  • the size of the treatment surface preferably relates in each case to the entire contact surface over which a skin part experiences a heat impulse.
  • the size of the treatment surface preferably corresponds to the sum of the individual partial surfaces. Such division into partial areas may be advantageous in certain manifestations of herpes as well as in the treatment of certain body sites.
  • the treatment surface is brought to the desired treatment temperature by means of at least one heating element.
  • the treatment surface corresponds to the surface of a heating plate, which is heated by means of a heating element, wherein, for example, a semiconductor device can be used.
  • the treatment surface may also designate a homogeneous material surface which is tempered by a plurality of heating elements. For example, it may be preferable to use two or four heating elements in order to bring the treatment surface to the treatment temperature in a particularly homogeneous and rapid manner.
  • a control device can regulate the heating of the heating element such that the treatment temperature is present at the treatment surface.
  • a control device can regulate the heating of the heating element such that the treatment temperature is present at the treatment surface.
  • control device is preferably an integrated circuit, processor, processor chip, microprocessor or microcontroller configured to regulate the temperature of the treatment surface by means of the at least one heating element according to the predetermined treatment temperature values.
  • a control device is characterized by compactness, reliability, cost efficiency, low power consumption and high control efficiency.
  • This control device may be included, for example, by the device. It may also be preferred that the control device is part of the mobile device, in particular if control of the device by the mobile device via the interface is desired.
  • the at least one heating element is a component for which various embodiments of the prior art are well known.
  • the heating element may comprise a power resistor, in which a well-defined temperature is generated as a function of the current flow.
  • a field effect transistor FET
  • FET field effect transistor
  • the energy dissipation in the transistor is used to generate heat and bring the treatment surface to the treatment temperature.
  • FETs are particularly preferred as heating elements because they allow small dimensions due to their small size.
  • FETs Particularly reactive and ensure a very fast response of the heating elements by a very dynamic heat generation and heat dissipation.
  • the described device preferably comprises a heating element, which is designed for example as an electric heating plate in the form of a round disc with a diameter of about 5 mm.
  • the heating element is preferably powered by a voltage source.
  • Connected to the heating element is preferably a temperature sensor.
  • the electrical signal generated by the temperature sensor is advantageously supplied to the control device, with which the temperature and the duration of maintaining the maximum temperature of the treatment surface is controlled. For example, by pressing a button, the heating phase is started by means of the control device in the heating element. As soon as the electrical signal emitted by the sensor has reached the appropriate magnitude of the predetermined maximum temperature at the heating element, the treatment phase preferably begins.
  • the timing is triggered in the control device, which preferably contains a time and temperature control.
  • the temperature control primarily ensures the maintenance of the maximum temperature while preventing it from exceeding it.
  • the heating process is preferably ended and the temperature of the heating plate adapts to the ambient temperature.
  • the treatment surface is heated in this device in the heating phase preferably to a maximum temperature from a range of 40 to 65 ° C, with a tolerance of ⁇ 3 ° C is maintained.
  • the maximum temperature in a heating phase for a period of preferably 2 to 20 seconds, more preferably 3 to 20 seconds, in particular 10 to 15 seconds maintained. It may also be preferred to customize the treatment phase.
  • the regulation device can control by the specification of the power supply to the heating element, which temperature is present at the treatment surface.
  • the correlation between current flow and / or voltage across the heating element can be determined with the temperature at the treatment surface by means of a calibration, so that a desired treatment temperature between 40 ° C and 65 ° C can always be set based on the calibration.
  • a temperature sensor which measures the temperature of the treatment area, wherein the regulating device regulates the power supply to the heating element on the basis of the temperature data.
  • the control device may for example comprise a microprocessor, which can evaluate measurement data and set current parameters. This allows the temperature to be controlled very efficiently and reliably.
  • Nerve ends of the C-fibers activated.
  • the C fibers designate the slow-conducting nerve fibers of the somatosensitive system and are responsible for pain perception.
  • the free ends of the C fibers which are also referred to as nociceptors, play an important role.
  • the nerve endings of the fibers are activated by tissue hormones (eg, histamine, serotonin, substance P). Also could
  • Mast cells near the nerve endings may be involved in the process by releasing the mediator tryptase.
  • the knowledge about the mechanism of action in herpes is exploited to a heat treatment in a surprising way the
  • Sensory perception which are triggered by the fibers to regulate.
  • the temperature parameters mentioned, and preferably also periods of time surprisingly also allow the treatment of herpes.
  • thermolabile poisons can be neutralized by insect bites.
  • TRPV1 and TRPV2 are activated at the same time.
  • the TRPVI is involved in acute heat-induced pain in healthy skin and regulates, for example, the hot sensation at temperatures around 45 ° to 50 ° C.
  • the TRPV2 is activated in the case of particularly severe, painful heat stimuli, which start at temperatures above 52 ° C.
  • TRPV1 The activation threshold of TRPV1 is between 40 ° C and 45 ° C, whereas that of TRPV2 is between 50 ° C and 53 ° (Yao et al 201 1, Somogyi et al., 2015, Cohen et al., 2014, Mergler et al ).
  • the device has at least one interface and is configured for a power supply of the device by a mobile device and / or for data transmission with a mobile device and / or for control by a mobile device via the interface.
  • An interface means that the device is configured to interact with and / or connect to another device. It may be a physical location where connection of the device to another device is possible. But it can also be another, optional connectivity of the device, with another device signals and / or energy
  • These may preferably be electrical signals or signals which can be converted by the device into electrical signals. It may also preferably be energy which is exchanged or transmitted.
  • this can be electrical energy or energy, which can preferably be converted by the device into electrical energy.
  • the other device is preferably a mobile device.
  • a mobile device may be, for example, a laptop, a mobile phone, a smartphone, a tablet computer, a notebook, a smartwatch and / or a power bank.
  • a connection made possible via such an interface preferably comprises three physical elements: an interface of the mobile device, the interface of the device and a transmission channel between the two.
  • the transmission channel may be, for example, a cable-based connection and / or a wireless transmission channel based on the transmission of energy, for example by electromagnetic radiation.
  • the two interfaces are designed in the form of a socket and a matching plug, and thus a direct connection can be produced, which preferably furthermore has a mechanically stable connection between the device and
  • the interface would preferably comprise a socket and / or a plug.
  • the interface is wireless or wired or for a direct
  • Plug connection with plug and socket includes the interface,
  • the interface may be a standardized interface, such as
  • Bluetooth, Lightning, USB, WLAN, etc. act. However, it may also be an interface developed individually for the device.
  • the interface can be wireless or wired.
  • a cable may be suitable both for transmitting electrical charge carriers, for example a copper cable, but it may also be a cable
  • a wireless transmission may preferably be based on the transmission of electromagnetic waves in the entire spectral range, for example light signals may be used for wireless transmission, but also shortwave, ultrashort and / or decimeter waves.
  • USB is preferably meant with the interface of the device a suitable for connection USB socket of the device. Furthermore, it is preferably meant that suitable data converters, line drivers,
  • USB socket Power supplies and / or processors are present to the USB socket
  • An interface can preferably be used for the transmission of data.
  • the device is preferably configured for data transmission with a mobile device via the interface.
  • Data is preferred information provided by an electronic
  • Data processing device can be output, received and / or processed.
  • On Data processing device is preferably a device selected from the group computer, microcomputer, processor, microprocessor, integrated circuit, smartphone, other mobile devices and / or control device. Preference is given to data in digital format, in particular in bits. However, analog data is also conceivable. Likewise, data may preferably be stored in a memory or on a storage medium.
  • Data transmission with a mobile device preferably designates the exchange of data with the mobile device.
  • data can preferably be received and / or sent by the device.
  • data may preferably be stored and / or processed by the device.
  • a data line should preferably be provided via the interface, preferably a plurality of parallel data lines between
  • Transmission between the mobile device and the interface can preferably take place via an interface of the mobile device, which, depending on the interface, can be wired and / or wireless, for example, as already described above.
  • the transmission between the interface of the device and the other components can be realized for example by physical signal lines in the form of cables, which allow the transmission of electrical signals.
  • At least one of the elements of the mobile device, the interface of the mobile device, the interface of the device and the electrical components of the device uses a different data format than at least one of the remaining elements from this group. Therefore, it may be preferred that at the junctions of these elements, which use different formats, there is at least one data converter which transmits the data in the direction of transmission into a data format suitable for the following element. If such a data converter is assigned to the interface of the device and / or follows it in the direction of the components of the device, this at least one data converter is preferably part of the device.
  • the device and / or its interface preferably comprises at least one data transmission device. This can transmit data of the device via the interface towards the mobile device.
  • the data can preferably from one in the
  • Device integrated control device are generated and / or present on a data memory of the device.
  • the data transmission device can also act as a data converter or comprise such a data converter.
  • a person skilled in the art will be aware of and / or be able to routinely set up suitable facilities.
  • the device preferably comprises at least one
  • Data receiving unit This can receive data coming from the mobile device via the interface, if necessary converting it into a suitable data format and, for example to a control device for further processing and / or a storage medium for storing in a suitable manner pass.
  • a control device for further processing and / or a storage medium for storing in a suitable manner pass.
  • a person skilled in the art knows possibilities of routinely implementing suitable units.
  • data transmission and reception units are combined in a common unit.
  • the device preferably comprises a memory, which can be used in the data transmission.
  • a memory which can be used in the data transmission.
  • This may be, for example, a memory selected from the group comprising solid state memory, RAM memory, ROM memory, EPROM memory, EEPROM memory, flash memory and / or to others
  • the data can be transmitted in parallel and / or serially.
  • a parallel data In a parallel
  • the data preferably contain the parameters relating to the treatment which the
  • Control device to be transmitted.
  • These parameters can be, for example, treatment parameters such as the treatment temperature, the duration of treatment and / or a chronological sequence of treatment temperatures to be used, in order to enable a specific temporal temperature profile during the treatment.
  • metadata can also be transmitted to the control device, from which specific treatment parameters are determined. This metadata can be
  • data related to the user for example, gender, age and / or individual treatment preferences may be transmitted by users.
  • Transmission of said data may equally well be performed by the device to the mobile device, for example, to transmit to the mobile device the treatment periods and treatment temperatures set by the user on the device and to associate user data concerning that user.
  • further relevant metadata can be generated, for example
  • the mobile device which is for example a smartphone, may generate further data, such as GPS position data, timestamps, photos of skin areas affected by pruritus, etc. These can all be linked and / or correlated, whereby statistically relevant data can be generated. which, for example, concern successful treatment therapies or a geographically and / or temporally limited occurrence of an insect pest. Also, the combination of mobile device and device further interesting applications are conceivable, such as a telephone medical treatment and / or advice.
  • the interface can preferably also or exclusively be used for the transmission of electrical energy.
  • the device is preferably configured for a
  • Powered by a mobile device via the interface it is preferable to enable energy transfer from the mobile device to the device via the interface.
  • the energy transfer provides in particular for the transmission of electrical energy.
  • the energy can also be transferred in other form and then converted by the device into electrical energy.
  • the transmission, in particular of electrical energy can take place by cable.
  • the interface is in particular formed by a possibility of cable connection between the mobile device or its interface and device.
  • the transmission can also take place wirelessly, from the side of the
  • the interface suitable for this purpose preferably consists of an energy converter, which converts the wirelessly transmitted energy into electrical energy, which can be used to power the device.
  • the electrical energy received at the interface is preferably transmitted to the elements of the device which consume electrical energy, such as the heating element or any integrated one
  • Control device This transmission can be achieved by suitable connections, e.g. B. by cable, can be realized.
  • an energy store as described below, be interposed and / or downstream.
  • suitable voltage regulator and / or charge controller for supplying and / or charging the energy storage and the electrical
  • both transmissions can take place in parallel of energy and data. It may also be preferred that interface use only for one type of transmission, for example for the transmission of electrical energy. Some interfaces, such as USB, provide parallel voltage and data transmission. Even with a wireless interface, electrical energy and / or data, preferably in parallel, can be transmitted, for example by induction coils or by electromagnetic radiation, which is converted into electrical voltage by solar cells and / or photodiodes.
  • the device is preferably configured for control by a mobile device via the interface.
  • the heating of the heating element in consideration of the treatment parameters, such as treatment temperature and duration of treatment to control.
  • the treatment parameters such as treatment temperature and duration of treatment to control.
  • Time information can be used. It may be preferred that the device itself has no control device and whose task is taken over by a suitable hardware and / or software of the mobile device. Thus, in this case, it is preferable that the mobile device comprises a control device. In this case, for example, it may be preferred that the control signals, for example for heating the heating element, be transmitted directly from the mobile device via the interface to this. The control can be carried out, for example, by controlling the transmitted current intensity and / or by a pulse width modulated signal from the mobile device. Likewise, the measured data of the
  • Temperature sensor via the interface directly to the mobile device and through this read directly or after a suitable signal conversion and used for control.
  • the device comprises a rudimentary processor, for example a microprocessor and / or a data converter, which converts the control commands of the mobile device into suitable signals for controlling the heating element.
  • a rudimentary processor for example a microprocessor and / or a data converter, which converts the control commands of the mobile device into suitable signals for controlling the heating element.
  • signals of the temperature sensor can be converted into signals suitable for the mobile device and transmitted to the latter via the interface.
  • the above-described data transmission can preferably be used.
  • the device For control by a mobile device via the interface, the device preferably has at least one electrical connection between interface and processor and / or heating element and / or temperature sensor. This can be done in the form of electrical cables.
  • data converters are provided between the interface and the said connected elements.
  • the device can be kept very simple, inexpensive and compact.
  • Existing control resources of the mobile device such as a smartphone, may be used.
  • the device comprises a control device, and only treatment parameters are transmitted from the mobile device to the control device. Such transmission may optionally be made before each treatment, but it may also be preferred that a transmission takes place only when new
  • the device comprises the device, the control device.
  • Control device may have the aforementioned properties and act in the manner described for controlling the heating element.
  • the device is configured for a parameterization of the control device by the mobile device.
  • usage parameters are transmitted from the mobile device via the interface to the control device of the device. These may in particular include treatment temperature and duration.
  • suitable parameters can be transmitted individually before each treatment for the respective user and his suffering. It can be a particularly individual treatment and the success of treatment can be increased.
  • a data transmission between the mobile device and the device can be used via the interface.
  • the device is configured for a transmission of a control program of the control device by the mobile device.
  • the control program preferably includes an algorithm that determines how
  • Treatment temperature and / or treatment time of the device can be controlled.
  • the control program may include, for example, certain control algorithms.
  • Control devices whose control algorithm can be changed after a single setting and more, as it is the case for example in some microprocessors
  • Regulating device can be used, which are programmable several times.
  • the program can be software-based and / or hardware-based.
  • a so-called Field Programmable Gate Array (FPGA) can be used as a control device, which can be completely reconnected by a transmitted control program. Its logical circuits, which result in the interaction of the control program, can thereby
  • a control program can be regularly updated and improved without having to replace the entire device.
  • a data transmission between the mobile device and the device can be used via the interface.
  • the mobile device comprises the control device.
  • the operation, the construction and the advantages of this embodiment have already been described above.
  • the device may be kept compact and, for example, directly interfaced with the mobile device, e.g. As a smartphone, are coupled.
  • a user may in this case use the device through his smartphone, for example by plugging the device onto the smartphone, wherein a mechanical connection is preferably effected by the coupling of the interfaces themselves, and the smartphone is used to control and / or handle the device .
  • the device itself may be shaped so that it is mechanically, for example by plugging, connectable to the mobile device and therefore a connection is possible even without a wired interface.
  • Such a device is very convenient and can be kept extremely small. It is advantageous that a user carries his mobile device, in particular his smartphone, usually permanently and can use the device in conjunction with this.
  • the device itself is used independently, for example, if a separate control device is present. Is at the same time its own, compact
  • the device can operate independently, but at the same time be kept very compact.
  • the power supply of the device can operate independently, but at the same time be kept very compact.
  • a wireless transmission of signals takes place via the interface.
  • This can be done for example in the form of electromagnetic waves, in particular by transmission of light signals.
  • the interface would preferably comprise at least one receiving unit and / or one transmitting unit.
  • a receiving unit could, for example, a suitable photoreceptor such. B. include a photodiode.
  • other optical elements, such as lenses, could be included that would be provided to those skilled in the art of free jet optical transmission.
  • a suitable light source such as a laser and / or an (organic) LED could be used.
  • suitable optical elements e.g. B. for collimation of the transmitted light beam use.
  • preferred converters and / or drivers would find application to convert between optical signals and appropriate internal electrical signals of the device.
  • an electromagnetic signal may preferably be based on electromagnetic waves in the non-visible spectral range, for example (near) infrared signals,
  • Shortwave, ultra shortwave and / or Dezimeterwellen be used. Again, a person skilled in the art would know how he would have to make the interface with suitable transmitters and / or receiving antennas, drivers and data converters and interconnections between interface and other electrical elements of the device.
  • a power supply of the device by a mobile device via the interface energy is preferably transmitted for example in the form of electromagnetic waves, which is then converted in the device into usable electrical energy and preferably forwarded to the electrical elements of the device and / or an energy storage.
  • a wireless power supply is described in detail below.
  • the treatment temperature is 40 ° C to 60 ° C and the size of the treatment area between 1 cm 2 and 18 cm 2 .
  • Power supply can be surprisingly compensated by a mobile device.
  • Treatment temperature 40 ° C to 60 ° C and the size of the treatment area is less than 1 cm 2 is.
  • Such a device is particularly well suited for the treatment of herpes, especially on the lip and mosquito bites. At the same time, such a device can be kept particularly compact.
  • the data obtained in the treatment of mosquito bites of a plurality of users and preferably a plurality of devices can advantageously be used for statistical evaluation. For example, mosquito infestations can be detected and predicted.
  • the mobile device is selected from the group comprising PC, laptop, desktop PC, mobile phone, smartphone, tablet computer, personal digital assistant (PDA), notebook, subnotebook, smart phone, walkman, discman, MP3 player,
  • PDA personal digital assistant
  • mobile devices have proven to be particularly practical for use with the device.
  • mobile devices which have a high own computing power and a high flexibility with regard to their application can form a particularly powerful system in connection with the device.
  • Such devices are represented for example by smartphones. These can be customized by the device
  • the device comprises at least one
  • Energy storage can be realized for example by at least one battery, a battery and / or a capacitor. What is meant is preferably an electrical energy store.
  • a battery is an energy store, preferably an electrochemical
  • Energy storage whose stored energy preferably can not be replenished after consumption. It can include zinc-manganese batteries, alkaline manganese batteries, zinc chloride batteries, zinc-carbon batteries, zinc-air batteries, mercury-zinc batteries, silver oxide zinc batteries, nickel oxyhydroxide batteries, lithium batteries; Lithium-iron sulfide batteries, aluminum-air batteries, bio-batteries, e.g. B. based on magnesium / NaCl / iron + molybdenum + tungsten and / or Edison-Lalander elements. Batteries can also be so-called button cells.
  • a capacitor is preferably an electrical component that stores electric charge in an electric field.
  • the energy storage device may in particular be at least one battery.
  • Batteries or accumulators are preferably rechargeable, in contrast to batteries.
  • Batteries can include lithium-ion batteries, lithium-cobalt dioxide batteries, lithium polymer batteries, lithium manganese batteries, lithium iron phosphate batteries, lithium iron yttrium phosphate batteries, lithium titanate batteries, lithium -Metal-polymer batteries, lithium-air batteries, lithium-sulfur batteries, sodium-nickel chloride high-temperature batteries, sodium-sulfur batteries, sodium-ion batteries, nickel-cadmium batteries, nickel-iron batteries , Nickel-Hydrogen Batteries, Nickel Metal Hydride Batteries, Nickel-Zinc Batteries, Lead Acid Batteries, PTMA Batteries, Rechargeable Alkaline Manganese Batteries, Tin Sulfur Lithium Batteries, Silver-Zinc Batteries, Vanadium Redox Batteries and / or zinc-bromine batteries, be silicon-air batteries. It is also possible to use lithium polymer and / or a metal-
  • This embodiment of the device has the advantage that it is supplied both with a connected interface with a mobile device, as well as self-sufficient with electrical energy.
  • the embodiment comprising at least one battery (or possibly also a capacitor) can be supplied with a connected mobile device via this with electrical energy and thereby charged.
  • the battery can be dimensioned so that it can be used for at least one application without a connected interface with the mobile device.
  • the device for use is not dependent on connection to the mobile device and is particularly flexible.
  • the battery comprises a solid-state battery, preferably a lithium-ceramic battery. This is characterized by a particularly high level of safety and is preferably also usable after a partial destruction.
  • the device is configured for a power supply and / or a charging of the energy store by wireless energy transmission, preferably via the interface.
  • the electrical energy is preferably transmitted without a signal to be charged between the device to be charged and the mobile device
  • connection via an electrical cable exists.
  • the electrical energy can be
  • inductive coupling can be used by at least one coil in each case in the mobile device and in the device. It may also be advantageous to capacitively couple the device and the mobile device by at least one capacitor plate in each case. Even over long distances can be transmitted by so-called far-field transmission preferably electrical energy, which is in the transmitted between the transmitter and receiver electromagnetic waves. Likewise, light emitted by the mobile device can be transmitted energy, which is converted into electrical voltage in at least one solar cell of the device. It may also be preferable to directly transmit electrical energy between conductive surfaces of the mobile device and the device via the contact existing between these surfaces. The transferred energy can be used directly for heating the heating element or preferably for charging a built-in battery in the device.
  • a person skilled in the art would know that he has the interface or device with suitable elements such.
  • B. at least one induction coil, a capacitor plate, an antenna, a solar cell, a photodiode, a charge controller and / or a voltage regulator and how he would have to interconnect the appropriate elements to realize the wireless energy transfer.
  • Control program and / or to control a wireless interface can be used, the use of cables can be completely avoided.
  • a sender in the wireless power transmission a mobile device may be used which serves only for this purpose and is plugged directly into a socket.
  • the device is configured for a power supply and / or a charging of the energy storage device by a cable, in particular via the interface.
  • the device in particular the interface, comprises a cable or plug and / or a socket for connection to a cable.
  • the electrical energy within the device is forwarded to suitable elements, in particular to the energy store, for example by means of connections. Interposed is advantageously a voltage regulator and / or charge controller.
  • suitable elements in particular to the energy store, for example by means of connections.
  • Interposed is advantageously a voltage regulator and / or charge controller.
  • a person skilled in suitable elements and their interconnections are known. A transmission of electrical energy in this way is particularly robust, energy efficient and cost-effective.
  • an interface is selected from the group comprising: Bluetooth, Lightning, Jack, Coaxial, Apple 30-pin dock connector, ASUS Media Bus proprietary, CAMAC, EISA, ISA, LPC, MBus, MCA, Multibus for Industrial Systems , NuBus or IEEE 1 196, OPTi local bus, PCI, ATA, PATA, IDE, EIDE, ATAPI, S-100 bus or IEEE 696, SBus or IEEE 1496, SS-50 bus, Runway bus, GSC / HSC, Precision bus , STbus, STD bus, Unibus, Q-Bus, VLB or VL-bus, VMEbus, PC / 104, PC / 104-Plus, PCI-104, PCI / 104-Express, PCI / 104, Zorro II and Zorro III, 1-Wire, HyperTransport, l 2 C, PCIe, SATA, SPI bus, UNI / O, SMBus, IrDA, WLAN, ZigBee, NFC
  • Interfaces proved their suitability for a multitude of different applications. It is known to a person skilled in the art how he would have to design such an interface. For example, one skilled in the art would know that he would need to install a suitable jack and / or plug for a Lightning interface, as well as know that he has suitable processors, e.g. B. Host controller would use. He would also know how to interconnect the electrical elements of the device with the interface. At z. B. a WLAN interface, the skilled person would also know that he would have to install at least one suitable antenna for sending and / or receiving signals in the device. The selection of suitable control processors, data converter and / or controller as well as an interconnection of the interface within the device is for the
  • Power supply and / or to charge directly to a power outlet to connect In a preferred embodiment, it is possible, for example, to obtain electrical energy directly from the socket by means of a commercially available USB charger.
  • the device comprises at least a first
  • Temperature sensor for measuring the temperature of the treatment surface
  • Regulating device and / or control provides based on the measured data of the
  • Temperature sensor the temperature of the at least one heating element.
  • a temperature sensor is preferably an electrical or electronic component which generates an electrical signal as a function of the temperature at the sensor.
  • a variety of temperature sensors are known, such as semiconductor temperature sensors, resistance temperature sensors, pyroelectric materials, thermocouples or quartz crystals.
  • the control device is furthermore preferably configured such that it can receive and evaluate the measured values of the temperature sensors in order to effect a regulation of the heating plates.
  • the regulation of the heating plates can preferably take place by means of the application of an electrical current or a voltage. It is particularly preferred that the temperature sensor directly measures the temperature of the treatment area, i.
  • the temperature sensor is in contact with the treatment surface, wherein the temperature sensor may be located both on the inner side of the treatment surface and on the outer side of the treatment surface or is implemented in the treatment surface.
  • the temperature sensor does not directly contact and monitor the treatment surface but rather the heating elements or a material point between the heating elements and the treatment surface.
  • the temperature sensor may also be preferable to place the temperature sensor between the heating elements. From the measurement data for the temperature over the heating elements or a measuring point at a certain distance to the treatment surface can also be concluded that the temperature of the treatment surface.
  • the temperature of the treatment area means the average temperature of the treatment area.
  • An evaluation of the temperature of the treatment surface allows a particularly precise regulation of the at least one heating element in order to ensure an optimal temperature distribution on the treatment surface and thus heat transfer to the skin parts to be treated.
  • a temperature-based feedback regulation using the control device suitable for performing a reliable hyperthermic treatment with optimal temperature values is particularly simple, robust and inexpensive.
  • the heating element heats the treatment surface to a treatment temperature of 40 ° C to 65 ° C.
  • a treatment temperature of 40 ° C to 65 ° C represents a surprisingly improved treatment of itching.
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, on.
  • the heating element heats the treatment surface to a treatment temperature of 42 ° C - 56 ° C.
  • the performance in treating itching could be surprisingly increased by the temperature range provided in this embodiment.
  • the heating element heats the treatment surface to a treatment temperature of 42 ° C - 53 ° C.
  • another means of treating itching may be provided.
  • the heating element heats the treatment surface to a treatment temperature of 43 ° C-47 ° C.
  • the effectiveness of these treatment temperatures in the treatment of itching is surprisingly large.
  • the electrical efficiency in terms of energy consumption is greater than in other temperature ranges.
  • the heating element heats the treatment surface to a treatment temperature of 50 ° C to 53 ° C. This temperature range has proven to be particularly effective and popular among subjects, so that great economic success is foreseeable.
  • the heating element heats the treatment surface to a treatment temperature of 50 ° C-55 ° C. In this temperature range, the yield of generated heat per consumed energy is particularly high.
  • the heating element heats the treatment surface to a treatment temperature of 55 ° C-60 ° C.
  • the treatment temperature in this range is surprisingly effective. Here it came to a happy grip, because from a wide
  • the heating element heats the treatment surface to a treatment temperature of 60 ° C-65 ° C. This temperature range was chosen contrary to the trend in scientific technique.
  • Treatment duration of 1 - 60 sec maintained.
  • the technical options for treating heat itching can be increased.
  • Treatment duration of 1 - 10 sec maintained. Such a short treatment time means a surprising saving of time in the treatment of itching.
  • Treatment duration of 20 - 30 sec maintained.
  • a second way of treating heat itch can be provided.
  • Treatment duration of 30 - 40 sec maintained. It has been found that the yield of the amount of heat released is particularly high during such a treatment period.
  • Treatment duration of 40 - 50 sec maintained. There were misconceptions in the art about the appropriate duration of treatment for the hyperthermic treatment of pruritus, which were overcome by this treatment period.
  • Treatment duration of 50 - 60 sec maintained. It can be so surprisingly avoided errors in the treatment of itching.
  • Treatment duration of 2 - 20 sec maintained. This treatment time represents a significant improvement over known methods of treating itching.
  • Treatment duration of 2 - 12 sec maintained. From a variety of conceivable or known treatment periods was selected by a happy handle this treatment time, which is surprisingly effective in the treatment of itching. This was not predictable.
  • the treatment temperature is maintained for a treatment time of 3 to 6 seconds. This short and at the same time particularly effective treatment duration can increase the efficiency of the device.
  • Treatment duration of 4 - 6 sec maintained. This treatment period represents a decisive departure from the technically usual.
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, and the
  • Treatment temperature is maintained for a treatment time of 2 to 12 seconds, preferably 3 to 6 seconds. Tests have shown that if the treatment is taken immediately after the sting, mosquito bites can be successfully inactivated at a maximum temperature of 55 ° C. The exposure time is not critical at a temperature of 55 ° C, so that the treatment at this temperature can be repeated several times if necessary. In addition, as a result of the anesthetic effect of insect venom, a heat treatment of the skin at the puncture site is perceived as significantly less uncomfortable than in other areas.
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 56 ° C and the treatment temperature is maintained for a treatment period of 2 seconds to 20 seconds.
  • the heat pulse causes a
  • Nerve stimulation which greatly reduces the subjective perception of pain or itching at the sites concerned.
  • the heat transfer leads surprisingly to a superposition of the unpleasant sensation by other temperature-dependent
  • Heat treatment activates the free nerve endings of the C fibers.
  • the knowledge of the mechanism of action in herpes is exploited to a
  • Heat treatment in a surprising way the sensory perception, which are triggered by the fibers to regulate.
  • a use of the device for the treatment of herpes allow the mentioned periods and temperature parameters in a surprising way.
  • itching disorders are e.g. after contact with venomous cnidarians or plants, such as stinging nettles or in insect bites and bites, treatable.
  • thermolabile poisons can be neutralized by insect bites.
  • thermo and capsaicin receptors TRPV1 and TRPV2 are activated at the same time.
  • a person skilled in the art would not assume that the activation of these receptors would be a particularly effective superposition of the allows unpleasant sensations, which also works in the treatment of herpes. This is a surprising insight.
  • This combination of treatment temperature and duration of treatment can also increase the technical options for treating itching.
  • the heating element heats the treatment surface to a treatment temperature of 49 ° C to 53 ° C and the treatment temperature is maintained for a treatment time of 3 to 20 sec.
  • Preferred treatment temperature and duration are surprisingly suitable caused by herpesviruses
  • the heating element heats the treatment surface to a treatment temperature between 40 ° C and 65 ° C and the treatment temperature is maintained for a treatment period of 4 sec to 6 sec.
  • a heat pulse is generated, which allows it a
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, and the treatment temperature is maintained for a treatment time of 4 seconds to 6 seconds. It has been completely surprising that with the aforementioned
  • a combination of a treatment temperature of 42 ° C and 53 ° C and in particular with the preferred treatment temperature between 50 ° C and 53 ° C allows an effect on the skin areas, which quickly and effectively relieve the itching. It has been recognized that it is possible to achieve a particularly pronounced superimposition of the itching sensation since the thermal and capsaicin receptors TRPV1 and TRPV2 are activated locally at the same time in the relevant skin areas.
  • the preferred mentioned embodiment which is a temperature control of
  • Treatment area in a narrow range between 50 ° C and 53 ° C allows, in a surprisingly effective way, a simultaneous activation of the receptors, without causing unpleasant strong pain sensations in the treated persons.
  • the range of the activation threshold of the TRPV2 could be determined as a particularly optimized effective range. This is likely to lead to a feedback mechanism between the receptors, which softens the itching particularly effectively, without
  • the prolonged mode of action of the preferred embodiment is due, at least in part, to immune regulation by heat transfer.
  • immune regulation by heat transfer.
  • Immune system the local irritation of the skin is actively suppressed.
  • a single treatment can already lead to a lasting decrease in itching sensation.
  • the intermittent transmission of heat with a treatment phase of 4 s to 6 s achieves an optimal effect on the signaling pathways of pruritus without causing unwanted side effects. It has surprisingly been found, especially for the preferred treatment time of 4s-6s and the intended treatment temperature, in particular for the particularly preferred treatment temperature of 50 ° C-53 ° C, that an exceptionally effective activation of TRPV1 and in particular the TRPV2
  • Treatment temperature and duration of treatment particularly effectively contributes to a reduction of itching. Also, the C-fibers, especially their free ends, are ideally addressed by this preferred choice.
  • the size of the treatment area is between 0.1 cm 2 to 18 cm 2 .
  • the technical possibilities for the treatment of itching can be increased.
  • the size of the treatment area is between 1 cm 2 to 18 cm 2 . With a treatment area of this size can also in a short time
  • Treatment success in the treatment of itching can be achieved.
  • the size of the treatment area is at least 6 cm 2 , preferably at least 7 cm 2 .
  • External stimuli of a chemical, mechanical or physical nature that can trigger feelings of itching are perceived by three different receptor cells (sensory cells). These sensory cells are so-called open nerve endings, whose stimulus-absorbing structures are located in the epidermis and the underlying dermis, and whose axons transmit the signals to the spinal cord via perceived stimuli. In these sensory cells, the unmyelated C-fibers are of particular importance. Their receptive structures are sometimes up to 0.1 mm below the skin surface.
  • the C-fibers are distinguished by polymodal mechanical and heat-sensitive fibers and mechanically Insensitive C-fibers, which can also be stimulated by heat. C-fibers not only take pruritogenic stimuli, but also serve as nociceptors (pain receptors).
  • Treatment area surprisingly be treated very effectively.
  • the professional world came from a completely different idea, the use of such large treatment areas were considered unrealizable.
  • the size of the treatment area is less than 1 cm 2 .
  • the size of the treatment area is less than 40 mm 2 .
  • the preferred maximum size of the treatment area is ideal to cover all possible affected areas.
  • a treatment area of 20 mm 2 is suitable to cover all typical affected areas of skin with only a single application of the device.
  • a herpes treatment device having such a treatment surface can be kept particularly compact.
  • device sizes corresponding to those of a lipstick can be achieved.
  • Such a compact device is readily and readily worn on the body or in a carry-on bag so that treatment can be made at any time. This significantly increases the success of the treatment.
  • the treatment area is preferably round, this is particularly suitable for the treatment of herpes, the affected skin areas often have organic, approximately round shape.
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, wherein the
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, wherein the
  • Treatment temperature for a treatment time of 2 to 12 sec, preferably 3 to 6 sec, is maintained and wherein the size of the treatment area at least 6 cm 2 , preferably at least 7 cm 2 .
  • the statements of the technical literature regarding a combination of treatment temperatures, duration of treatment and treatment surface have mistakenly pointed in a different direction.
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, wherein the
  • the heating element heats the treatment surface to a treatment temperature of 50 to 65 ° C, preferably 55 to 60 ° C, wherein the
  • Treatment temperature for a treatment time of 2 to 12 sec, preferably 3 to 6 sec, is maintained and wherein the size of the treatment area is less than 40 mm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 56 ° C, wherein the treatment temperature for a treatment time of 2 sec to 20 sec is maintained and wherein the size of the treatment area between 1 cm 2 to 18 cm 2 is.
  • a treatment temperature between 42 ° C and 56 ° C, wherein the treatment temperature for a treatment time of 2 sec to 20 sec is maintained and wherein the size of the treatment area between 1 cm 2 to 18 cm 2 is.
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 56 ° C, wherein the treatment temperature for a treatment time of 2 sec to 20 sec is maintained and wherein the size of the treatment surface at least 6 cm 2 , preferably at least 7th cm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 56 ° C, wherein the treatment temperature for a treatment time of 2 sec to 20 sec is maintained and wherein the size of the treatment surface is less than 1 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 56 ° C, the treatment temperature being maintained for a treatment time of 2 seconds to 20 seconds and wherein the size of the treatment surface is less than 40 mm 2 .
  • the heating element heats the treatment surface to a treatment temperature of 49 ° C to 53 ° C, wherein the treatment temperature for a treatment time of 3 to 20 sec is maintained and wherein the size of the
  • Treatment area between 1 cm 2 to 18 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature of 49 ° C to 53 ° C, wherein the treatment temperature for a treatment time of 3 to 20 sec is maintained and wherein the size of the
  • Treatment surface at least 6 cm 2 , preferably at least 7 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature of 49 ° C to 53 ° C, wherein the treatment temperature for a treatment time of 3 to 20 sec is maintained and wherein the size of the
  • Treatment area is less than 1 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature of 49 ° C to 53 ° C, wherein the treatment temperature for a treatment time of 3 to 20 sec is maintained and wherein the size of the
  • Treatment area is less than 40 mm 2 .
  • Another means for the treatment of itching and especially herpes can be provided.
  • the heating element heats the treatment surface to a treatment temperature between 40 ° C and 65 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and the size of the
  • the heating element heats the treatment surface to a treatment temperature between 40 ° C and 65 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and the size of the
  • Treatment surface at least 6 cm 2 , preferably at least 7 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 40 ° C and 65 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and the size of the
  • Treatment area is less than 1 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 40 ° C and 65 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and the size of the
  • Treatment area is less than 40 mm 2 .
  • Treatment time of 4 to 6 seconds can be treated very flexible various ailments of the skin, which cause itching.
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and wherein the Size of the treatment area is between 1 cm 2 to 18 cm 2 .
  • a device which has this combination has proven to be surprisingly low maintenance and robust. Even under adverse conditions, for example, high humidity and high heat, the device works surprisingly flawless.
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and wherein the Size of the treatment area is at least 6 cm 2 , preferably at least 7 cm 2 .
  • the effectiveness of the treatment is particularly high.
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and wherein the Size of the treatment area is less than 1 cm 2 .
  • a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and wherein the Size of the treatment area is less than 1 cm 2 .
  • the heating element heats the treatment surface to a treatment temperature between 42 ° C and 53 ° C, more preferably between 50 ° C and 53 ° C, wherein the treatment temperature for a treatment time of 4 sec to 6 sec is maintained and wherein the Size of the treatment area is less than 40 mm 2 .
  • a hardware-implemented temperature monitor reversibly limits the maximum temperature of the treatment surface and a fuse switches off the device in the event of a short circuit or uncontrolled heating.
  • the maximum temperature preferably designates that temperature which reaches the treatment surface at most during the treatment phase.
  • the hardware-implemented temperature monitor allows
  • indications such as approximately, approximately, nearly or synonymous terms preferably designate a tolerance range of less than ⁇ 10%, preferably less than ⁇ 5%, particularly preferably less than ⁇ 1%.
  • a "hardware-implemented temperature monitor” preferably designates a temperature control system for the treatment surface, which can switch off the power supply of the heating elements for the treatment surface in a hardware-based manner from the regulation of the heating elements by the
  • Regulating device so e.g. the microprocessor.
  • a firmware is installed to regulate the heating elements, for example on the control device, then it is preferred that the hardware-implemented temperature monitor reliably limits the maximum temperature of the treatment surface even in the event of failure or faulty execution of the firmware. As a result, it can be ensured in a particularly effective manner by simple structural means that the treatment surface of the device does not exceed a maximum temperature. Even under the occurrence of faulty controls in the control device, for example, after the ingress of liquids, can be advantageously ensured at any time due to the hardware-based temperature monitor that the treatment area a
  • the device according to the invention has a fuse, which in case of a short circuit of the device or unregulated fürskyen the
  • a fuse preferably means an overcurrent protection device, in which, for example, by the melting of a fuse conductor, a circuit can be interrupted as soon as the current exceeds a limit over a time to be determined. It is preferred that the fuse in the device be present between the supply of the supply voltage to the device and the device itself. Should there be an accident, which is characterized in that a
  • the fuse advantageously switches off the complete power supply of the device.
  • a fuse provides on the one hand a sufficiently fast, on the other hand an extremely reliable protection.
  • Providing a hardware-implemented temperature monitor can not be ruled out that due to incorrect operation or damage to the device, in very rare cases comes to a heating of the heating elements.
  • heating the heating elements is preferably understood in the context of the invention that the temperature of the heating elements uncontrolled, i. not increased by a temperature-based control using the control device. If in these incidents the
  • the treatment area can increase uncontrollably to temperatures well above the desired treatment temperature, for example to temperatures well above 65 ° C.
  • the skin areas to be hyperthermally treated are for the most part particularly sensitive and are characterized, for example, by reddening, swelling or even wound formation.
  • a markedly elevated temperature above 65 ° C can lead to severe pain and skin burns locally at these sites.
  • the said fuse is particularly advantageous to even in the most unlikely event of a failure, a shutdown of the heating
  • Power supply of the device is a central regulatory interface, which meets the highest security requirements.
  • By integrating the fuse in the current flow to supply the device can be ensured that a maximum supply current is not exceeded during a certain time. Since a heating and an uncontrolled heating of the heating elements over the desired temperature with an increased current flow is connected, thereby overheating of the treatment surface can be avoided in a particularly reliable manner.
  • safety mechanism could also be due to thermal
  • the device according to the invention shows a particularly advantageous and synergistic effect of the combined use of a hardware-implemented temperature monitor and a fuse.
  • a fuse that after the single triggering this has a permanent decoupling of the supply voltage from the device result.
  • a re-commissioning of the device after the release of the fuse needs repair by a technician, such as the replacement of the fuse.
  • the device is usually at triggering the
  • the hardware-implemented temperature monitor is set so that it does not have to come to a permanent shutdown of the power supply of the device. Rather, the hardware-implemented temperature monitor is designed so that when the temperature of the treatment surface exceeds a maximum temperature, during the
  • Period of exceeding the power supply of the heating elements is interrupted.
  • the power interruption by the hardware-implemented temperature monitor is thus advantageously reversible, i. as soon as the temperature of the treatment surface falls below the maximum temperature again, the heating elements can heat again.
  • the intended use of the device can be continued.
  • the user would possibly not notice the malfunction because the selected maximum temperature, the effectiveness and the independence of the hardware-implemented temperature monitor would not cause the user unpleasant temperatures and the device would be able to function properly again in the event of a single mis-control the next time it is used.
  • Mobile devices may be subject to technical problems that counteract secure control. For example, mobile devices may be infested with computer viruses. Then it is good if the device has its own
  • Safety mechanism has, which is preferably two stages.
  • the hardware-implemented temperature monitor allows shutdown of the heating elements regardless of the control device. Even with such a disturbance of the control device, a fuse would not be triggered. Only in the very rare case that both the control device and the hardware-implemented temperature monitor fail, for example in the event of damage to the corresponding components, does the fuse ensure a final control element. If there is an increased power requirement of the heating elements due to a strong heating, the fuse switches off the entire power supply of the device. Due to this staggering of the security mechanisms, a one-time disturbance of the control device can be intercepted extremely safely. The hardware-implemented temperature monitor goes unnoticed and fast without affecting the usability of the device. By means of the downstream fuse, an even higher level of security can be achieved, so that the user can be provided with an extremely effective and safe treatment device.
  • the maximum temperature is between 54 ° C and 58 ° C, preferably about 56 ° C. It has surprisingly been found that by a
  • the hardware-implemented temperature monitor comprises at least one second temperature sensor for measuring the temperature of the
  • Treatment area with the maximum temperature compares and when exceeding the
  • a comparator preferably designates an electronic circuit for comparing two voltages, wherein it is indicated at the output in a binary manner, which of the two voltages is higher.
  • Comparators are known which are suitable for outputting from two analog voltages a binary output signal which states which of the input voltage is higher.
  • An example of a comparator circuit is the Schmitt trigger. It is preferred that a reference value for a voltage is applied to an input of the comparator with the aid of a voltage distributor. This reference value preferably corresponds to the voltage value which the second temperature sensor would have if the temperature of the
  • Treatment area is equal to the maximum temperature.
  • the output voltage of the temperature sensor which depends on the temperature of the treatment surface.
  • a particularly preferred temperature sensor for this purpose comprises an NTC thermistor, ie a thermistor. This one has a negative Temperature coefficients such that as the temperature increases, the resistance drops and a higher current flows. But it can also PTC thermistors are used, which have a positive temperature coefficient, so that with an increase in the temperature, the resistance increases and a lower current flows.
  • the output signal at the comparator changes to binary.
  • the comparator is preferably integrated in the power supply of the heating elements. That before the temperature of the treatment surface reaches the maximum temperature, the comparator preferably releases the supply voltage of the heating elements. However, as soon as the temperature is higher than the maximum temperature, the output of the comparator switches off and interrupts the supply voltage of the heating elements. If the temperature of the treatment surface falls again, the supply voltage is advantageously released again by the comparator. As a result, a reversible switching on and off of the heating elements only for the period, while the temperature of the treatment surface exceeds the maximum temperature. Furthermore, it may be preferred that the comparator is enabled by the control device when starting the device. Thus, if a proper start of the device is not performed, the comparator in the default setting is configured so that the power supply of the heating elements is interrupted.
  • Temperature monitor has proven in tests to be particularly robust and reliable. Due to the reversibility of the safety shutdown and simple design, the preferred embodiment is further characterized by low manufacturing and maintenance costs.
  • the fuse has a maximum current threshold corresponding to heating the treatment area to 65 ° C for 1 second. Tests have shown that only a temperature increase of more than 65 ° C for more than 1 second is very critical for the sensation of pain and can lead to damage to the skin.
  • the fuse does not prematurely become uncritical Temperature increases triggered the treatment area. This can increase profitability without compromising safety.
  • the person skilled in the art knows from the electrical parameters of the heating elements which fuse should be selected in order to ensure the given values. For this purpose, a measurement of the power supply can be carried out with simultaneous measurement of the temperature of the treatment area.
  • a nimble fuse which responds to a current increase within preferably less than 20 milliseconds (ms).
  • the threshold value of the fuse is preferably between 1 A and 2.5 A, more preferably approximately 2 A. Tests have shown that, with respect to the preferred heating elements, the thresholds specified reliably ensure that the temperature of the treatment surface is at a temperature of 65 ° C to 70 ° C for not longer than 1 second.
  • Temperature monitor to a value between 54 ° C and 58 ° C preferably from about 56 ° C can also be ensured that the distance is large enough to the temperature at the release of the fuse due to a current value above the threshold. Thus, an accidental release of the fuse, which at least one exchange the backup would be avoided as long as there is no serious malfunction involving the hardware-implemented temperature monitor.
  • the invention relates to a system of device and mobile device, wherein the device is configured for power supply by the mobile device and / or for data exchange with the mobile device and / or for control by the mobile device via an interface.
  • control device is included in the device, but it may also be preferred that the mobile device comprises the control device, in particular when controlled by the mobile device via an interface.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Signal Processing (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

Dans un premier aspect, l'invention concerne un dispositif pour le traitement hyperthermique d'un prurit. Le dispositif comprend au moins une surface de traitement, laquelle peut être chauffée par chauffage d'au moins un élément chauffant à une température de traitement de 40 °C à 65 °C et peut être commandée par un dispositif de régulation. Le dispositif présente au moins une interface et est configuré pour alimenter le dispositif en courant au moyen d'un appareil mobile et/ou pour échanger des données avec un appareil mobile et/ou pour être commandé par un appareil mobile par l'intermédiaire de l'interface. Dans un autre aspect, l'invention concerne un système composé d'un dispositif et d'un appareil mobile, le dispositif étant configuré pour être alimenté en courant par l'appareil mobile et/ou pour échanger des données avec l'appareil mobile et/ou pour être commandé par l'appareil mobile par l'intermédiaire d'une interface.
EP19729518.1A 2018-06-07 2019-06-06 Dispositif mobile à interface pour le traitement d'un prurit Pending EP3801413A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18176545.4A EP3578146A1 (fr) 2018-06-07 2018-06-07 Dispositif mobile de traitement de démangeaisons pourvu d'interface
PCT/EP2019/064817 WO2019234172A1 (fr) 2018-06-07 2019-06-06 Dispositif mobile à interface pour le traitement d'un prurit

Publications (1)

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EP3801413A1 true EP3801413A1 (fr) 2021-04-14

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EP18176545.4A Withdrawn EP3578146A1 (fr) 2018-06-07 2018-06-07 Dispositif mobile de traitement de démangeaisons pourvu d'interface
EP19729518.1A Pending EP3801413A1 (fr) 2018-06-07 2019-06-06 Dispositif mobile à interface pour le traitement d'un prurit

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EP18176545.4A Withdrawn EP3578146A1 (fr) 2018-06-07 2018-06-07 Dispositif mobile de traitement de démangeaisons pourvu d'interface

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US (1) US20210236327A1 (fr)
EP (2) EP3578146A1 (fr)
JP (1) JP2021525618A (fr)
KR (1) KR20210018891A (fr)
CN (1) CN112533562A (fr)
AU (1) AU2019283424A1 (fr)
CA (1) CA3102351A1 (fr)
IL (1) IL279211A (fr)
WO (1) WO2019234172A1 (fr)

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CN111771840A (zh) * 2020-07-07 2020-10-16 时光科技(中山)有限公司 多功能灭蚊器
CN217366261U (zh) * 2022-01-24 2022-09-06 中山市特莱斯电子有限公司 一种止痒器

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Publication number Publication date
EP3578146A1 (fr) 2019-12-11
CA3102351A1 (fr) 2019-12-12
WO2019234172A1 (fr) 2019-12-12
KR20210018891A (ko) 2021-02-18
JP2021525618A (ja) 2021-09-27
AU2019283424A1 (en) 2021-01-21
CN112533562A (zh) 2021-03-19
IL279211A (en) 2021-01-31
US20210236327A1 (en) 2021-08-05

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