EP3755319A1 - Composés et compositions pour le traitement de troubles musculaires - Google Patents
Composés et compositions pour le traitement de troubles musculairesInfo
- Publication number
- EP3755319A1 EP3755319A1 EP19756654.0A EP19756654A EP3755319A1 EP 3755319 A1 EP3755319 A1 EP 3755319A1 EP 19756654 A EP19756654 A EP 19756654A EP 3755319 A1 EP3755319 A1 EP 3755319A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- epicatechin
- bone
- composition
- muscle
- weakness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/900,533 US20180193306A1 (en) | 2012-03-23 | 2018-02-20 | Compounds and compositions for the treatment of muscular disorders and bone disorders |
PCT/US2019/018730 WO2019164914A1 (fr) | 2018-02-20 | 2019-02-20 | Composés et compositions pour le traitement de troubles musculaires |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3755319A1 true EP3755319A1 (fr) | 2020-12-30 |
EP3755319A4 EP3755319A4 (fr) | 2021-12-01 |
Family
ID=67687368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19756654.0A Withdrawn EP3755319A4 (fr) | 2018-02-20 | 2019-02-20 | Composés et compositions pour le traitement de troubles musculaires |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP3755319A4 (fr) |
JP (1) | JP2021514380A (fr) |
CN (1) | CN111989098A (fr) |
AU (1) | AU2019224003A1 (fr) |
BR (1) | BR112020016923A2 (fr) |
CA (1) | CA3091892A1 (fr) |
IL (1) | IL276786A (fr) |
WO (1) | WO2019164914A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012170430A1 (fr) | 2011-06-06 | 2012-12-13 | Cardero Therapeutics, Inc. | Méthodes et compositions pour le traitement de la toxicité mitochondriale |
US10898465B2 (en) | 2016-06-21 | 2021-01-26 | Epirium Bio Inc. | Utility of (+) epicatechin and their analogs |
US11918570B2 (en) | 2020-04-13 | 2024-03-05 | The Research Foundation For The State University Of New York | Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition |
WO2024036225A1 (fr) * | 2022-08-10 | 2024-02-15 | Epirium Bio Inc. | Épicatéchine pour l'inhibition de la toxicité du glutamate |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003072714A2 (fr) * | 2002-02-21 | 2003-09-04 | Wyeth | Domaine follistatine contenant des proteines |
JP2004161669A (ja) * | 2002-11-13 | 2004-06-10 | Ito En Ltd | 骨形成促進剤 |
CN100361655C (zh) * | 2005-09-05 | 2008-01-16 | 中山大学 | (-)-表没食子儿茶素没食子酸酯-钙络合物固体分散体及其制备方法与应用 |
CA2690685A1 (fr) * | 2007-06-20 | 2008-12-24 | Galapagos N.V. | Cibles et composes moleculaires utiles dans le traitement de maladies degeneratives des os et des articulations, et procedes pour les identifier |
US9119818B2 (en) * | 2008-05-14 | 2015-09-01 | Agriculture Victoria Services Pty Ltd | Use of angiogenin or angiogenin agonists for treating diseases and disorders |
JP2010095474A (ja) * | 2008-10-17 | 2010-04-30 | Ito En Ltd | カルシウム吸収促進組成物及びカルシウム吸収促進飲食物 |
KR101096574B1 (ko) * | 2008-12-12 | 2011-12-20 | 에이치 엘 지노믹스(주) | 유럽종 포도의 씨 추출물을 함유하는 골다공증 예방 또는 치료용 약학 조성물 |
JP2011006355A (ja) * | 2009-06-25 | 2011-01-13 | Ito En Ltd | 骨密度改善組成物及び飲食物 |
JP2013051920A (ja) * | 2011-09-05 | 2013-03-21 | Ishikawa Prefectural Public Univ Corp | 骨密度強化補助食品 |
WO2013142816A1 (fr) * | 2012-03-23 | 2013-09-26 | Cardero Therapeutics, Inc. | Composés et compositions pour le traitement d'affections musculaires |
EP2903458B1 (fr) * | 2012-10-04 | 2018-09-05 | Abbott Laboratories | Méthodes d'amélioration de l'effet de l'egcg sur l'atténuation de la perte musculaire squelettique |
CA3057129C (fr) * | 2014-06-16 | 2021-07-20 | Unigen, Inc. | Compositions et methodes de prise en charge ou d'attenuation de troubles osseux, de troubles du cartilage ou des deux |
-
2019
- 2019-02-20 WO PCT/US2019/018730 patent/WO2019164914A1/fr unknown
- 2019-02-20 BR BR112020016923-4A patent/BR112020016923A2/pt not_active Application Discontinuation
- 2019-02-20 AU AU2019224003A patent/AU2019224003A1/en active Pending
- 2019-02-20 EP EP19756654.0A patent/EP3755319A4/fr not_active Withdrawn
- 2019-02-20 CA CA3091892A patent/CA3091892A1/fr active Pending
- 2019-02-20 JP JP2020544632A patent/JP2021514380A/ja active Pending
- 2019-02-20 CN CN201980026811.XA patent/CN111989098A/zh active Pending
-
2020
- 2020-08-18 IL IL276786A patent/IL276786A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL276786A (en) | 2020-10-29 |
WO2019164914A1 (fr) | 2019-08-29 |
BR112020016923A2 (pt) | 2020-12-15 |
CN111989098A (zh) | 2020-11-24 |
CA3091892A1 (fr) | 2019-08-29 |
EP3755319A4 (fr) | 2021-12-01 |
AU2019224003A1 (en) | 2020-10-08 |
JP2021514380A (ja) | 2021-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20200915 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20211103 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/00 20060101ALI20211027BHEP Ipc: A61K 33/06 20060101ALI20211027BHEP Ipc: A61K 31/593 20060101ALI20211027BHEP Ipc: C07D 311/74 20060101ALI20211027BHEP Ipc: C07D 311/62 20060101ALI20211027BHEP Ipc: A61P 19/10 20060101ALI20211027BHEP Ipc: A61P 19/08 20060101ALI20211027BHEP Ipc: A61K 31/353 20060101AFI20211027BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20220604 |