EP3645728A4 - Neuartige typ-vi-crispr-orthologe und systeme - Google Patents
Neuartige typ-vi-crispr-orthologe und systeme Download PDFInfo
- Publication number
- EP3645728A4 EP3645728A4 EP18824952.8A EP18824952A EP3645728A4 EP 3645728 A4 EP3645728 A4 EP 3645728A4 EP 18824952 A EP18824952 A EP 18824952A EP 3645728 A4 EP3645728 A4 EP 3645728A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- systems
- novel type
- crispr orthologs
- orthologs
- crispr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/85—Fusion polypeptide containing an RNA binding domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762525165P | 2017-06-26 | 2017-06-26 | |
US201762566851P | 2017-10-02 | 2017-10-02 | |
PCT/US2018/039595 WO2019005866A1 (en) | 2017-06-26 | 2018-06-26 | NEW TYPE VI CRISPR ORTHOLOGISTS AND ASSOCIATED SYSTEMS |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3645728A1 EP3645728A1 (de) | 2020-05-06 |
EP3645728A4 true EP3645728A4 (de) | 2021-03-24 |
Family
ID=64741890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18824952.8A Pending EP3645728A4 (de) | 2017-06-26 | 2018-06-26 | Neuartige typ-vi-crispr-orthologe und systeme |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3645728A4 (de) |
WO (1) | WO2019005866A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11174515B2 (en) | 2017-03-15 | 2021-11-16 | The Broad Institute, Inc. | CRISPR effector system based diagnostics |
US11104937B2 (en) | 2017-03-15 | 2021-08-31 | The Broad Institute, Inc. | CRISPR effector system based diagnostics |
WO2018183908A1 (en) | 2017-03-31 | 2018-10-04 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating ovarian tumors |
US11618928B2 (en) | 2017-04-12 | 2023-04-04 | The Broad Institute, Inc. | CRISPR effector system based diagnostics for malaria detection |
BR112020006757A2 (pt) | 2017-10-04 | 2020-10-06 | The Broad Institute Inc. | diagnóstico baseado no sistema de efetor crispr |
WO2019113506A1 (en) | 2017-12-07 | 2019-06-13 | The Broad Institute, Inc. | Methods and compositions for multiplexing single cell and single nuclei sequencing |
CN114900773A (zh) | 2017-12-14 | 2022-08-12 | 弗洛设计声能学公司 | 声泳系统及其操作方法、控制声换能器及声学系统的方法 |
US11957695B2 (en) | 2018-04-26 | 2024-04-16 | The Broad Institute, Inc. | Methods and compositions targeting glucocorticoid signaling for modulating immune responses |
SG11202012786RA (en) | 2018-06-26 | 2021-01-28 | Massachusetts Inst Technology | Crispr effector system based amplification methods, systems, and diagnostics |
BR112020026246A2 (pt) | 2018-06-26 | 2021-04-20 | The Broad Institute Inc. | composições, sistemas e métodos de amplificação com base em nickase dupla crispr |
WO2020124050A1 (en) | 2018-12-13 | 2020-06-18 | The Broad Institute, Inc. | Tiled assays using crispr-cas based detection |
US11739156B2 (en) | 2019-01-06 | 2023-08-29 | The Broad Institute, Inc. Massachusetts Institute of Technology | Methods and compositions for overcoming immunosuppression |
CN110157695A (zh) * | 2019-01-25 | 2019-08-23 | 南昌大学 | 一种植物RNA m5C甲基化修饰的系统及方法 |
US20220154258A1 (en) | 2019-03-14 | 2022-05-19 | The Broad Institute, Inc. | Crispr effector system based multiplex diagnostics |
US20220177863A1 (en) | 2019-03-18 | 2022-06-09 | The Broad Institute, Inc. | Type vii crispr proteins and systems |
WO2020245785A2 (en) * | 2019-06-06 | 2020-12-10 | Tata Consultancy Services Limited | Method and system for identification of candidate target sites for combating pathogens |
WO2021046257A1 (en) | 2019-09-03 | 2021-03-11 | The Broad Institute, Inc. | Crispr effector system based multiplex cancer diagnostics |
US11844800B2 (en) | 2019-10-30 | 2023-12-19 | Massachusetts Institute Of Technology | Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia |
US20230374528A1 (en) * | 2020-08-17 | 2023-11-23 | University Of Maryland, College Park | Compositions, systems, and methods for orthogonal genome engineering in plants |
US20230023791A1 (en) | 2021-06-01 | 2023-01-26 | Arbor Biotechnologies, Inc. | Gene editing systems comprising a crispr nuclease and uses thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016205764A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Novel crispr enzymes and systems |
WO2016205749A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Novel crispr enzymes and systems |
WO2018107129A1 (en) * | 2016-12-09 | 2018-06-14 | The Broad Institute, Inc. | Crispr effector system based diagnostics |
-
2018
- 2018-06-26 WO PCT/US2018/039595 patent/WO2019005866A1/en unknown
- 2018-06-26 EP EP18824952.8A patent/EP3645728A4/de active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016205764A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Novel crispr enzymes and systems |
WO2016205749A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Novel crispr enzymes and systems |
WO2018107129A1 (en) * | 2016-12-09 | 2018-06-14 | The Broad Institute, Inc. | Crispr effector system based diagnostics |
Non-Patent Citations (2)
Title |
---|
See also references of WO2019005866A1 * |
SHMAKOV SERGEY ET AL: "Diversity and evolution of class 2 CRISPR-Cas systems", NATURE REVIEWS. MICROBIOLOGY, NATURE PUBLISHING GROUP, ENGLAND, vol. 15, no. 3, 23 January 2017 (2017-01-23) - 1 March 2017 (2017-03-01), pages 169 - 182, XP002767857, ISSN: 1740-1534, DOI: 10.1038/NRMICRO.2016.184 * |
Also Published As
Publication number | Publication date |
---|---|
WO2019005866A1 (en) | 2019-01-03 |
EP3645728A1 (de) | 2020-05-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3655530A4 (de) | Neuartige typ-vi-crispr-orthologe und systeme | |
EP3645728A4 (de) | Neuartige typ-vi-crispr-orthologe und systeme | |
EP3727469A4 (de) | Neuartige crispr-enzyme und systeme | |
EP3755792A4 (de) | Neue cas9-orthologe | |
EP3500671A4 (de) | Neuartige crispr-enzyme und -systeme | |
EP3500670A4 (de) | Neuartige crispr-enzyme und -systeme | |
IL281159A (en) | New CRISPR enzymes and systems | |
EP3545085A4 (de) | Crispr/cpf1-system und -verfahren | |
HK1253001A1 (zh) | 新型crispr酶以及系统 | |
EP3679130A4 (de) | Diagnosesysteme auf der basis von multieffektor-crispr | |
SG10202010311SA (en) | Novel Crispr Enzymes and Systems | |
EP3681888A4 (de) | Pyrazolopyrimidinonverbindungen und verwendungen davon | |
EP3313530A4 (de) | 4,6-pyrimidinylenderivate und verwendung davon | |
EP3387196A4 (de) | Verbindungssysteme zwischen träger und säule und momentbeständige rahmen damit | |
EP3719424A4 (de) | Kühlschrank und kühlschranksystem | |
EP3654982A4 (de) | 1,8-naphthyridinonverbindungen und deren verwendungen | |
EP3700934A4 (de) | Verbindungen und verwendungen davon | |
EP3884065A4 (de) | Direct-to-library-methoden, systeme und zusammensetzungen | |
EP3585511A4 (de) | Metallmolybdat und verfahren zur herstellung davon | |
EP3359676A4 (de) | Transposonsystem, kit damit und verwendungen davon | |
EP3692008A4 (de) | Biozementverfahren und -systeme | |
EP3551619A4 (de) | Zusammensetzungen mit methylphenidat-prodrugs, verfahren zur herstellung und verwendung davon | |
EP3720281A4 (de) | Pestizidzusammensetzungen und -verfahren | |
EP3697409A4 (de) | Cannabidiol- und chitosan-zusammensetzungen und verfahren zu deren verwendung | |
EP3612230A4 (de) | Palbociclib-zusammensetzungen und verfahren dafür |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20200122 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20210219 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/63 20060101AFI20210216BHEP Ipc: C12N 15/82 20060101ALI20210216BHEP Ipc: C12N 9/22 20060101ALI20210216BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20221121 |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230527 |