EP3645728A4 - Nouveaux orthologues de crispr de type vi et systèmes associés - Google Patents
Nouveaux orthologues de crispr de type vi et systèmes associés Download PDFInfo
- Publication number
- EP3645728A4 EP3645728A4 EP18824952.8A EP18824952A EP3645728A4 EP 3645728 A4 EP3645728 A4 EP 3645728A4 EP 18824952 A EP18824952 A EP 18824952A EP 3645728 A4 EP3645728 A4 EP 3645728A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- systems
- novel type
- crispr orthologs
- orthologs
- crispr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/85—Fusion polypeptide containing an RNA binding domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762525165P | 2017-06-26 | 2017-06-26 | |
US201762566851P | 2017-10-02 | 2017-10-02 | |
PCT/US2018/039595 WO2019005866A1 (fr) | 2017-06-26 | 2018-06-26 | Nouveaux orthologues de crispr de type vi et systèmes associés |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3645728A1 EP3645728A1 (fr) | 2020-05-06 |
EP3645728A4 true EP3645728A4 (fr) | 2021-03-24 |
Family
ID=64741890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18824952.8A Pending EP3645728A4 (fr) | 2017-06-26 | 2018-06-26 | Nouveaux orthologues de crispr de type vi et systèmes associés |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3645728A4 (fr) |
WO (1) | WO2019005866A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
CA2935960C (fr) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Dispositif d'acoustophorese avec double chambre acoustophoretique |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11104937B2 (en) | 2017-03-15 | 2021-08-31 | The Broad Institute, Inc. | CRISPR effector system based diagnostics |
US11174515B2 (en) | 2017-03-15 | 2021-11-16 | The Broad Institute, Inc. | CRISPR effector system based diagnostics |
WO2018183908A1 (fr) | 2017-03-31 | 2018-10-04 | Dana-Farber Cancer Institute, Inc. | Compositions et méthodes de traitement de tumeurs ovariennes |
US11618928B2 (en) | 2017-04-12 | 2023-04-04 | The Broad Institute, Inc. | CRISPR effector system based diagnostics for malaria detection |
JP2020537121A (ja) | 2017-10-04 | 2020-12-17 | ザ・ブロード・インスティテュート・インコーポレイテッド | Crisprエフェクター系に基づく診断 |
US11332736B2 (en) | 2017-12-07 | 2022-05-17 | The Broad Institute, Inc. | Methods and compositions for multiplexing single cell and single nuclei sequencing |
BR112020009889A2 (pt) | 2017-12-14 | 2020-11-03 | Flodesign Sonics, Inc. | acionador e controlador de transdutor acústico |
US11957695B2 (en) | 2018-04-26 | 2024-04-16 | The Broad Institute, Inc. | Methods and compositions targeting glucocorticoid signaling for modulating immune responses |
MX2020013836A (es) | 2018-06-26 | 2021-05-27 | Massachusetts Inst Technology | Métodos, sistemas y diagnósticos de amplificación basados en el sistema efector crispr. |
BR112020026246A2 (pt) | 2018-06-26 | 2021-04-20 | The Broad Institute Inc. | composições, sistemas e métodos de amplificação com base em nickase dupla crispr |
WO2020124050A1 (fr) | 2018-12-13 | 2020-06-18 | The Broad Institute, Inc. | Dosages en mosaïque à l'aide d'une détection basée sur crispr-cas |
US11739156B2 (en) | 2019-01-06 | 2023-08-29 | The Broad Institute, Inc. Massachusetts Institute of Technology | Methods and compositions for overcoming immunosuppression |
CN110157695A (zh) * | 2019-01-25 | 2019-08-23 | 南昌大学 | 一种植物RNA m5C甲基化修饰的系统及方法 |
US20220154258A1 (en) | 2019-03-14 | 2022-05-19 | The Broad Institute, Inc. | Crispr effector system based multiplex diagnostics |
US20220177863A1 (en) | 2019-03-18 | 2022-06-09 | The Broad Institute, Inc. | Type vii crispr proteins and systems |
EP3979832A4 (fr) * | 2019-06-06 | 2023-06-21 | Tata Consultancy Services Limited | Procédé et système d'identification de sites cibles candidats pour lutter contre des agents pathogènes |
WO2021046257A1 (fr) | 2019-09-03 | 2021-03-11 | The Broad Institute, Inc. | Diagnostic du cancer multiplex basé sur un système effecteur crispr |
US11844800B2 (en) | 2019-10-30 | 2023-12-19 | Massachusetts Institute Of Technology | Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia |
US20230374528A1 (en) * | 2020-08-17 | 2023-11-23 | University Of Maryland, College Park | Compositions, systems, and methods for orthogonal genome engineering in plants |
CA3222023A1 (fr) | 2021-06-01 | 2022-12-08 | Arbor Biotechnologies, Inc. | Systemes d'edition de genes comprenant une nuclease crispr et leurs utilisations |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016205764A1 (fr) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Nouvelles enzymes crispr et systèmes associés |
WO2016205749A1 (fr) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Nouvelles enzymes crispr et systèmes associés |
WO2018107129A1 (fr) * | 2016-12-09 | 2018-06-14 | The Broad Institute, Inc. | Diagnostics basés sur un système effecteur crispr |
-
2018
- 2018-06-26 WO PCT/US2018/039595 patent/WO2019005866A1/fr unknown
- 2018-06-26 EP EP18824952.8A patent/EP3645728A4/fr active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016205764A1 (fr) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Nouvelles enzymes crispr et systèmes associés |
WO2016205749A1 (fr) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Nouvelles enzymes crispr et systèmes associés |
WO2018107129A1 (fr) * | 2016-12-09 | 2018-06-14 | The Broad Institute, Inc. | Diagnostics basés sur un système effecteur crispr |
Non-Patent Citations (2)
Title |
---|
See also references of WO2019005866A1 * |
SHMAKOV SERGEY ET AL: "Diversity and evolution of class 2 CRISPR-Cas systems", NATURE REVIEWS. MICROBIOLOGY, NATURE PUBLISHING GROUP, ENGLAND, vol. 15, no. 3, 23 January 2017 (2017-01-23) - 1 March 2017 (2017-03-01), pages 169 - 182, XP002767857, ISSN: 1740-1534, DOI: 10.1038/NRMICRO.2016.184 * |
Also Published As
Publication number | Publication date |
---|---|
WO2019005866A1 (fr) | 2019-01-03 |
EP3645728A1 (fr) | 2020-05-06 |
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Legal Events
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STAA | Information on the status of an ep patent application or granted ep patent |
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Effective date: 20200122 |
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Extension state: BA ME |
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DAV | Request for validation of the european patent (deleted) | ||
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20210219 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/63 20060101AFI20210216BHEP Ipc: C12N 15/82 20060101ALI20210216BHEP Ipc: C12N 9/22 20060101ALI20210216BHEP |
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STAA | Information on the status of an ep patent application or granted ep patent |
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Effective date: 20221121 |
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P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230527 |