SG11202012786RA - Crispr effector system based amplification methods, systems, and diagnostics - Google Patents
Crispr effector system based amplification methods, systems, and diagnosticsInfo
- Publication number
- SG11202012786RA SG11202012786RA SG11202012786RA SG11202012786RA SG11202012786RA SG 11202012786R A SG11202012786R A SG 11202012786RA SG 11202012786R A SG11202012786R A SG 11202012786RA SG 11202012786R A SG11202012786R A SG 11202012786RA SG 11202012786R A SG11202012786R A SG 11202012786RA
- Authority
- SG
- Singapore
- Prior art keywords
- diagnostics
- systems
- system based
- amplification methods
- based amplification
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
- C12Q2521/301—Endonuclease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/513—Winding/unwinding enzyme, e.g. helicase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862690257P | 2018-06-26 | 2018-06-26 | |
| US201862767052P | 2018-11-14 | 2018-11-14 | |
| US201962818650P | 2019-03-14 | 2019-03-14 | |
| PCT/US2019/039167 WO2020006036A1 (en) | 2018-06-26 | 2019-06-26 | Crispr effector system based amplification methods, systems, and diagnostics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202012786RA true SG11202012786RA (en) | 2021-01-28 |
Family
ID=67263107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202012786RA SG11202012786RA (en) | 2018-06-26 | 2019-06-26 | Crispr effector system based amplification methods, systems, and diagnostics |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20210269866A1 (en) |
| EP (1) | EP3814527B1 (en) |
| JP (1) | JP2021528090A (en) |
| KR (1) | KR20210040943A (en) |
| CN (1) | CN112543812A (en) |
| AU (1) | AU2019294630A1 (en) |
| BR (1) | BR112020026306A2 (en) |
| CA (1) | CA3102163A1 (en) |
| IL (1) | IL279065A (en) |
| MX (1) | MX2020013836A (en) |
| SG (1) | SG11202012786RA (en) |
| WO (1) | WO2020006036A1 (en) |
| ZA (1) | ZA202007610B (en) |
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| US11957695B2 (en) | 2018-04-26 | 2024-04-16 | The Broad Institute, Inc. | Methods and compositions targeting glucocorticoid signaling for modulating immune responses |
| JP7500549B2 (en) * | 2018-09-20 | 2024-06-17 | インスティテュート オブ ズーオロジー、チャイニーズ アカデミー オブ サイエンシーズ | Methods for detecting nucleic acids |
| CN111118218B (en) * | 2020-01-20 | 2024-01-23 | 杭州奥盛仪器有限公司 | Isothermal detection primer set, kit and detection method for CRISPR-Cas12a protease of prawn iridovirus |
| CN113337488B (en) * | 2020-03-02 | 2024-04-19 | 中国科学院分子细胞科学卓越创新中心 | Isolated Cas13 protein |
| US20240279718A1 (en) * | 2020-03-18 | 2024-08-22 | University Of Connecticut | Crispr-cas12a reaction for rapid and highly sensitive isothermal nucleic acid detection |
| US11761031B2 (en) | 2020-05-28 | 2023-09-19 | The Hong Kong University Of Science And Technology | Method for real time monitoring of nucleic acid amplicons mediated by loop oligonucleotide probes |
| WO2021254267A1 (en) * | 2020-06-16 | 2021-12-23 | 山东舜丰生物科技有限公司 | Method for detecting target nucleic acid using nucleic acid analogue or base modification |
| CN112029838B (en) * | 2020-07-23 | 2022-07-12 | 东南大学 | CRISPR/Cas9 typing PCR method for DNA homogeneous phase detection and application thereof |
| WO2022104381A1 (en) * | 2020-11-13 | 2022-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | A MINIMAL CRISPRi/a SYSTEM FOR TARGETED GENOME REGULATION |
| CN114507716B (en) * | 2020-11-16 | 2024-07-12 | 北京迅识科技有限公司 | Method for detecting target nucleic acid in sample |
| CN112980924B (en) * | 2021-02-10 | 2023-07-25 | 华南师范大学 | Amplification-free DNA single-molecule quantitative detection method, kit and buffer solution |
| US20240287592A1 (en) | 2021-06-10 | 2024-08-29 | New England Biolabs, Inc. | An Isothermal Diagnostic Test that Utilizes a Cas Protein and a Polymerase |
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| CN113584134B (en) * | 2021-09-06 | 2024-01-30 | 青岛金斯达生物技术有限公司 | Isothermal nucleic acid detection system based on CRISPR-Cas9, and method and application thereof |
| WO2023167752A2 (en) * | 2021-12-09 | 2023-09-07 | The Broad Institute, Inc. | Small novel crispr-cas systems and methods of use thereof |
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| US20230279375A1 (en) | 2021-12-13 | 2023-09-07 | Labsimply, Inc. | Signal boost cascade assay |
| CN114410752B (en) * | 2022-01-24 | 2024-06-25 | 华南师范大学 | Light-control-based CRISPR-Cas nucleic acid detection kit and detection method |
| GB202214125D0 (en) | 2022-09-27 | 2022-11-09 | Genomic Labs Ltd | Nucleic acid amplification; improved methods |
| US12091689B2 (en) | 2022-09-30 | 2024-09-17 | Vedabio, Inc. | Delivery of therapeutics in vivo via a CRISPR-based cascade system |
| WO2024076473A1 (en) | 2022-10-02 | 2024-04-11 | Vedabio, Inc. | Dimerization screening assays |
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| WO2024111543A1 (en) * | 2022-11-25 | 2024-05-30 | 国立研究開発法人理化学研究所 | Method and kit for detecting target nucleic acid |
| US12091690B2 (en) | 2023-01-07 | 2024-09-17 | Vedabio, Inc. | Engineered nucleic acid-guided nucleases |
| WO2024151493A1 (en) | 2023-01-10 | 2024-07-18 | Vedabio, Inc. | Sample splitting for multiplexed detection of nucleic acids without amplification |
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-
2019
- 2019-06-26 JP JP2020572975A patent/JP2021528090A/en active Pending
- 2019-06-26 SG SG11202012786RA patent/SG11202012786RA/en unknown
- 2019-06-26 AU AU2019294630A patent/AU2019294630A1/en active Pending
- 2019-06-26 MX MX2020013836A patent/MX2020013836A/en unknown
- 2019-06-26 KR KR1020217001812A patent/KR20210040943A/en not_active Application Discontinuation
- 2019-06-26 WO PCT/US2019/039167 patent/WO2020006036A1/en active Application Filing
- 2019-06-26 BR BR112020026306-0A patent/BR112020026306A2/en unknown
- 2019-06-26 EP EP19739825.8A patent/EP3814527B1/en active Active
- 2019-06-26 US US16/973,061 patent/US20210269866A1/en active Pending
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- 2019-06-26 CA CA3102163A patent/CA3102163A1/en active Pending
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2020
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|---|---|
| BR112020026306A2 (en) | 2021-03-30 |
| EP3814527B1 (en) | 2023-02-22 |
| JP2021528090A (en) | 2021-10-21 |
| MX2020013836A (en) | 2021-05-27 |
| US20210269866A1 (en) | 2021-09-02 |
| CA3102163A1 (en) | 2020-01-02 |
| EP3814527A1 (en) | 2021-05-05 |
| KR20210040943A (en) | 2021-04-14 |
| WO2020006036A1 (en) | 2020-01-02 |
| AU2019294630A1 (en) | 2020-12-17 |
| CN112543812A (en) | 2021-03-23 |
| ZA202007610B (en) | 2023-06-28 |
| IL279065A (en) | 2021-01-31 |
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