EP3589373A4 - Compositions et méthodes pour immunothérapie - Google Patents

Compositions et méthodes pour immunothérapie Download PDF

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Publication number
EP3589373A4
EP3589373A4 EP18761512.5A EP18761512A EP3589373A4 EP 3589373 A4 EP3589373 A4 EP 3589373A4 EP 18761512 A EP18761512 A EP 18761512A EP 3589373 A4 EP3589373 A4 EP 3589373A4
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EP
European Patent Office
Prior art keywords
immunotherapy
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18761512.5A
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German (de)
English (en)
Other versions
EP3589373A1 (fr
Inventor
Vipin Suri
Kutlu Goksu ELPEK
Michelle Lynn OLS
Brian DOLINSKI
Nicole KOSMIDER
Scott Francis HELLER
Abhishek KULKARNI
Mara Christine INNISS
Dan Jun LI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Obsidian Therapeutics Inc
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Obsidian Therapeutics Inc
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Publication date
Application filed by Obsidian Therapeutics Inc filed Critical Obsidian Therapeutics Inc
Publication of EP3589373A1 publication Critical patent/EP3589373A1/fr
Publication of EP3589373A4 publication Critical patent/EP3589373A4/fr
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K39/4631Chimeric Antigen Receptors [CAR]
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    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
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    • A61K39/464402Receptors, cell surface antigens or cell surface determinants
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    • A61K39/464403Receptors for growth factors
    • A61K39/464406Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
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    • A61K39/464411Immunoglobulin superfamily
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    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • C12N9/003Dihydrofolate reductase [DHFR] (1.5.1.3)
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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EP18761512.5A 2017-03-03 2018-03-02 Compositions et méthodes pour immunothérapie Pending EP3589373A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762466601P 2017-03-03 2017-03-03
US201762484063P 2017-04-11 2017-04-11
US201762542402P 2017-08-08 2017-08-08
PCT/US2018/020704 WO2018160993A1 (fr) 2017-03-03 2018-03-02 Compositions et méthodes pour immunothérapie

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JP2020511528A (ja) 2020-04-16
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