EP3523321A4 - Compositions et procédés d'expression et d'administration de protéines - Google Patents

Compositions et procédés d'expression et d'administration de protéines Download PDF

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Publication number
EP3523321A4
EP3523321A4 EP17858829.9A EP17858829A EP3523321A4 EP 3523321 A4 EP3523321 A4 EP 3523321A4 EP 17858829 A EP17858829 A EP 17858829A EP 3523321 A4 EP3523321 A4 EP 3523321A4
Authority
EP
European Patent Office
Prior art keywords
delivery
compositions
methods
protein expression
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17858829.9A
Other languages
German (de)
English (en)
Other versions
EP3523321A1 (fr
Inventor
Chester Lee DRUM
Nihar MASURKAR
Siddharth DESHPANDE
Goutam CHAKRABORTY
Girish VALLERINTEAVIDE MAVELLI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Singapore
Original Assignee
National University of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Singapore filed Critical National University of Singapore
Publication of EP3523321A1 publication Critical patent/EP3523321A1/fr
Publication of EP3523321A4 publication Critical patent/EP3523321A4/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP17858829.9A 2016-10-07 2017-10-06 Compositions et procédés d'expression et d'administration de protéines Pending EP3523321A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662405613P 2016-10-07 2016-10-07
PCT/SG2017/050505 WO2018067075A1 (fr) 2016-10-07 2017-10-06 Compositions et procédés d'expression et d'administration de protéines

Publications (2)

Publication Number Publication Date
EP3523321A1 EP3523321A1 (fr) 2019-08-14
EP3523321A4 true EP3523321A4 (fr) 2020-07-08

Family

ID=61831159

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17858829.9A Pending EP3523321A4 (fr) 2016-10-07 2017-10-06 Compositions et procédés d'expression et d'administration de protéines

Country Status (8)

Country Link
US (1) US11510881B2 (fr)
EP (1) EP3523321A4 (fr)
JP (1) JP7096239B2 (fr)
KR (1) KR102579209B1 (fr)
CN (1) CN110023328B (fr)
IL (1) IL265831B1 (fr)
SG (2) SG10201911421VA (fr)
WO (1) WO2018067075A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019092481A (ja) * 2017-11-27 2019-06-20 国立大学法人東京工業大学 ヘテロタンパク質ケージ
JP2019193594A (ja) * 2018-05-01 2019-11-07 国立大学法人東京工業大学 融合タンパク質及びその使用
KR20220057542A (ko) * 2019-09-05 2022-05-09 아지노모토 가부시키가이샤 펩타이드 내포 페리틴
CN112094861B (zh) * 2020-10-26 2022-11-22 南京林业大学 一种绿藻植物铁蛋白的表达纯化方法及其应用
WO2024043836A1 (fr) * 2022-08-25 2024-02-29 National University Of Singapore Administration de protéine stabilisée par un tractus gastro-intestinal à l'aide d'un système de tes de disulfure

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033613B2 (en) * 2001-05-14 2006-04-25 Matsushita Electric Industrial Co., Ltd. Recombinant cage-like protein, method for producing the same, precious metal-recombinant cage-like protein complex, method for producing the same and recombinant DNA
WO2016048246A1 (fr) * 2014-09-25 2016-03-31 Nanyang Technological University Ciblage de mélanocytes pour une administration d'agents diagnostiques ou thérapeutiques au moyen de nanocages protéiques
EP3250233A4 (fr) * 2015-01-29 2018-07-25 Agency for Science, Technology and Research Nanocapsules contenant des peptides associés au chikungunya

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LUCAS: "UNIPROT:H9UBI8", 7 September 2016 (2016-09-07), XP055698930, Retrieved from the Internet <URL:https://www.uniprot.org/uniprot/H9UBI8.txt?version=26> [retrieved on 20200527] *
WEI SUN ET AL: "Salt-Dependent Aggregation and Assembly of E coli -Expressed Ferritin", DOSE-RESPONSE, vol. 14, no. 1, 26 February 2016 (2016-02-26), US, XP055699458, ISSN: 1559-3258, DOI: 10.1177/1559325816632102 *

Also Published As

Publication number Publication date
IL265831A (en) 2019-06-30
SG11201902945SA (en) 2019-05-30
JP2019534700A (ja) 2019-12-05
IL265831B1 (en) 2024-09-01
CN110023328B (zh) 2024-03-05
CN110023328A (zh) 2019-07-16
WO2018067075A1 (fr) 2018-04-12
US20210113484A1 (en) 2021-04-22
EP3523321A1 (fr) 2019-08-14
US11510881B2 (en) 2022-11-29
KR102579209B1 (ko) 2023-09-15
SG10201911421VA (en) 2020-02-27
KR20190062483A (ko) 2019-06-05
JP7096239B2 (ja) 2022-07-05

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