EP3497444A4 - Nachweis und quantifizierung von natalizumab - Google Patents

Nachweis und quantifizierung von natalizumab Download PDF

Info

Publication number
EP3497444A4
EP3497444A4 EP17840339.0A EP17840339A EP3497444A4 EP 3497444 A4 EP3497444 A4 EP 3497444A4 EP 17840339 A EP17840339 A EP 17840339A EP 3497444 A4 EP3497444 A4 EP 3497444A4
Authority
EP
European Patent Office
Prior art keywords
natalizumab
quantification
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17840339.0A
Other languages
English (en)
French (fr)
Other versions
EP3497444A1 (de
Inventor
Bradley T. Messmer
Dina UZRI
Jessie-Farah Fecteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abreos Biosciences Inc
Original Assignee
Abreos Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abreos Biosciences Inc filed Critical Abreos Biosciences Inc
Publication of EP3497444A1 publication Critical patent/EP3497444A1/de
Publication of EP3497444A4 publication Critical patent/EP3497444A4/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
EP17840339.0A 2016-08-12 2017-08-11 Nachweis und quantifizierung von natalizumab Pending EP3497444A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662374217P 2016-08-12 2016-08-12
PCT/US2017/046499 WO2018031887A1 (en) 2016-08-12 2017-08-11 Detection and quantification of natalizumab

Publications (2)

Publication Number Publication Date
EP3497444A1 EP3497444A1 (de) 2019-06-19
EP3497444A4 true EP3497444A4 (de) 2020-11-11

Family

ID=61163422

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17840339.0A Pending EP3497444A4 (de) 2016-08-12 2017-08-11 Nachweis und quantifizierung von natalizumab

Country Status (3)

Country Link
US (2) US11680948B2 (de)
EP (1) EP3497444A4 (de)
WO (1) WO2018031887A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018031887A1 (en) 2016-08-12 2018-02-15 Abreos Biosciences, Inc. Detection and quantification of natalizumab

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150293086A1 (en) * 2014-04-14 2015-10-15 Abreos Biosciences, Inc. Lateral flow immunoassay
US20160146829A1 (en) * 2008-03-27 2016-05-26 The Regents Of The University Of California Methods for detecting antibodies

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089605A (en) 1987-03-13 1992-02-18 Repligen Corporation Immobilized immunoglobulin-binding proteins
DE3911539A1 (de) 1989-04-08 1990-10-11 Boehringer Mannheim Gmbh Testtraeger-analysesystem
US6596476B1 (en) * 1989-12-22 2003-07-22 Abbott Laboratories Hepatitis C assay
DE4041905A1 (de) 1990-12-27 1992-07-02 Boehringer Mannheim Gmbh Testtraeger-analysesystem
US5567594A (en) 1991-04-26 1996-10-22 Enteron, L.P. Methods and compositions for the detection and treatment of diseases associated with antigens of microorganisms
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
DE4402756A1 (de) 1994-01-31 1995-08-03 Boehringer Mannheim Gmbh Spezifische Bindungssubstanzen für Antikörper und deren Verwendung für Immunoassays oder Vakzine
US5885577A (en) 1994-09-21 1999-03-23 Cytogen Corporation Antigen binding peptides (abtides) from peptide libraries
GB9502112D0 (en) 1995-02-03 1995-03-22 British Biocell Int Assay device and method
US7074888B1 (en) 1995-03-17 2006-07-11 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
WO1999053059A1 (en) 1998-04-16 1999-10-21 Genentech, Inc. Secretion of glycosylated proteins using a tissue plasminogen activator pro-sequence
US7112661B1 (en) 1998-10-30 2006-09-26 The Research Foundation Of State University Of New York Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
CA2418131A1 (en) 2000-08-03 2002-02-14 Inverness Medical Switzerland Gmbh Peptides capable of functioning as mimotopes for estradiol analytes
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
ATE443259T1 (de) 2001-09-20 2009-10-15 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper- komplexe mit elisa-tests
US20030091986A1 (en) 2001-11-09 2003-05-15 Regents Of The University Of California, Office Of Technology Transfer Identification of expressed genes using phage display
US20060286379A1 (en) 2002-08-13 2006-12-21 Yong Gao Magnetic nanoparticle supports
US7459314B2 (en) 2003-02-13 2008-12-02 Inverness Medical Switzerland Gmbh Lateral flow immunoassay controls
US7365154B2 (en) 2003-06-23 2008-04-29 Centocor, Inc. Peptides antagonistic to an anti-angiogenic antibody and uses therefor
JP2008505048A (ja) 2003-09-19 2008-02-21 ザ スクリップス リサーチ インスティテュート ４Ｅ１０Ｆａｂフラグメント複合体の広範囲中和性抗ＨＩＶ抗体構造に結合するペプチド、それらの使用、それら由来の組成物
US20050272106A1 (en) 2004-02-17 2005-12-08 Norman Moore Methods and kits for detection of multiple pathogens
US7781226B2 (en) 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US20060008920A1 (en) 2004-07-09 2006-01-12 Branan Medical Corporation Combination assay for alcohol and drugs of abuse
ATE548657T1 (de) * 2004-07-20 2012-03-15 Symphogen As Prozedur zur strukturellen charakterisierung rekombinanter polyclonaler proteine oder einer polyclonalen zelllinie
US20060068501A1 (en) 2004-09-30 2006-03-30 Nj International Llc Apparatus and methods for steroid hormone testing
US20070021591A1 (en) 2005-07-25 2007-01-25 Trubion Pharmaceuticals, Inc. Compositions and methods for protein deaggregation
WO2007022557A1 (en) 2005-08-23 2007-03-01 Diatech Pty Ltd Mimotopes of epstein-barr virus (ebv) epitopes
KR101282251B1 (ko) 2006-05-23 2013-07-10 삼성전자주식회사 디스플레이 장치, 이미지 처리 장치 및 그 제어 방법
WO2009003177A1 (en) 2007-06-27 2008-12-31 Inbios International, Inc. Lateral flow assay system and methods for its use
USD579459S1 (en) 2007-08-03 2008-10-28 Nec Display Solutions Of America, Inc. Projector screen with an image
JP2010536355A (ja) 2007-08-31 2010-12-02 エフ．ホフマン−ラ ロシュ アーゲー グリコシル化プロファイル分析
US8394602B2 (en) 2007-11-12 2013-03-12 Hiroshima University Luminescent method for measuring endotoxin
US8975378B2 (en) 2008-12-25 2015-03-10 Osaka University Human anti-human influenza virus antibody
GB0905519D0 (en) 2009-03-31 2009-05-13 Biofortuna Ltd Assay method and device
US20120220051A1 (en) 2009-07-08 2012-08-30 Anp Technologies, Inc. Immunogenicity Assay
EP2485762B1 (de) 2009-10-11 2017-12-13 Biogen MA Inc. Anti-vla-4-assays
KR20120096932A (ko) 2009-11-17 2012-08-31 아박시스, 인크. 라임병 항체의 검출을 위한 펩티드 및 방법
KR100946566B1 (ko) 2009-11-18 2010-03-11 주식회사 인포피아 측방 유동 면역 분석 디바이스
US9336353B2 (en) 2010-06-25 2016-05-10 Dexcom, Inc. Systems and methods for communicating sensor data between communication devices of a glucose monitoring system
ES2537207T3 (es) 2010-08-16 2015-06-03 Novimmune S.A. Métodos para la generación de anticuerpos multiespecíficos y multivalentes
US20130085349A1 (en) 2011-06-21 2013-04-04 Yofimeter, Llc Analyte testing devices
US20130040401A1 (en) 2011-08-12 2013-02-14 Benedict L. Zin Test strip reader
US9020476B2 (en) 2011-09-12 2015-04-28 Leipzig Technology, Llc System and method for remote care and monitoring using a mobile device
DK3489685T3 (da) 2011-11-21 2023-12-04 Zoetis Services Llc Signalforstærkning i sidestrømning og tilsvarende immunoassays
US20130143246A1 (en) 2011-12-02 2013-06-06 Lifescan Scotland Ltd. Hand-held test meter with analytical test strip ejection mechanism
USD731528S1 (en) 2012-05-15 2015-06-09 Fujitsu Limited Display with a graphical user interface
USD750115S1 (en) 2012-12-05 2016-02-23 Ivoclar Vivadent Ag Display screen or a portion thereof having an animated graphical user interface
USD732062S1 (en) 2013-02-22 2015-06-16 Samsung Electronics Co., Ltd. Display screen or a portion thereof with graphical user interface
USD701875S1 (en) 2013-02-25 2014-04-01 Pepsico, Inc. Display screen with graphical user interface
AU2015247338B2 (en) 2014-04-17 2020-10-08 Z-Integrated Digital Technologies, Inc. Electronic test device data communication
USD780188S1 (en) 2014-05-12 2017-02-28 Tencent Technology (Shenzhen) Company Limited Display screen or portion thereof with graphical user interface
USD757040S1 (en) 2014-05-29 2016-05-24 Comcast Cable Communications, Llc Display screen with animated graphical user interface
EP2982987A1 (de) 2014-08-08 2016-02-10 Proteomika, S.L. Lateralfluss-Immunoassays zum Nachweis von Antikörpern gegen biologische Arzneimittel
WO2016123105A1 (en) 2015-01-26 2016-08-04 Abreos Biosciences, Inc. Cleavage coupled competitive lateral flow assay
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
USD771072S1 (en) 2015-04-27 2016-11-08 Lutron Electronics Co., Inc. Display screen or portion thereof with graphical user interface
CN108431018A (zh) 2015-06-12 2018-08-21 王天欣 药物应用中蛋白质修饰的方法
WO2017008844A1 (en) 2015-07-14 2017-01-19 Biontech Ag Peptide mimotopes of the cd3 t-cell co-receptor epsilon chain and uses thereof
USD766936S1 (en) 2015-07-29 2016-09-20 Solar Turbines Incorporated Display screen or portion thereof with icon
JP1557056S (de) 2015-09-15 2016-08-29
USD774205S1 (en) 2015-12-24 2016-12-13 Beckman Coulter, Inc. Diagnostic device
USD807380S1 (en) 2016-04-13 2018-01-09 Vudu, Inc. Display screen or portion thereof with graphical user interface
JP1572568S (de) 2016-04-19 2020-03-09
JP1572567S (de) 2016-04-19 2020-03-09
USD805527S1 (en) 2016-05-05 2017-12-19 Chris Steven Ternoey Display screen portion with animated graphical user interface
USD805526S1 (en) 2016-05-05 2017-12-19 Chris Steven Ternoey Display screen portion with animated graphical user interface
JP1594017S (de) 2016-05-13 2018-01-09
USD806091S1 (en) 2016-05-16 2017-12-26 Google Llc Display screen with animated graphical user interface
USD800912S1 (en) 2016-06-17 2017-10-24 Abreos Biosciences, Inc. Point-of-care diagnostic device
WO2018031887A1 (en) 2016-08-12 2018-02-15 Abreos Biosciences, Inc. Detection and quantification of natalizumab
USD798316S1 (en) 2016-10-26 2017-09-26 Microsoft Corporation Display screen with graphical user interface
US20180291059A1 (en) 2017-04-04 2018-10-11 Abreos Biosciences, Inc. Immunoaffinity purification of antibodies using mimetopes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160146829A1 (en) * 2008-03-27 2016-05-26 The Regents Of The University Of California Methods for detecting antibodies
US20150293086A1 (en) * 2014-04-14 2015-10-15 Abreos Biosciences, Inc. Lateral flow immunoassay

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANA B SANCHEZ ET AL: "A general process for the development of peptide-based immunoassays for monoclonal antibodies", CANCER CHEMOTHERAPY AND PHARMACOLOGY, SPRINGER, BERLIN, DE, vol. 66, no. 5, 20 January 2010 (2010-01-20), pages 919 - 925, XP019843365, ISSN: 1432-0843 *
DANILA GUAGNOZZI ET AL: "Natalizumab in the treatment of Crohn's disease", BIOLOGICS: TARGETS AND THERAPY, vol. 2, no. 2, 1 June 2008 (2008-06-01), pages 275, XP055543602, ISSN: 1177-5475, DOI: 10.2147/BTT.S2935 *

Also Published As

Publication number Publication date
EP3497444A1 (de) 2019-06-19
WO2018031887A1 (en) 2018-02-15
US11680948B2 (en) 2023-06-20
US20230417761A1 (en) 2023-12-28
US20210285959A1 (en) 2021-09-16

Similar Documents

Publication Publication Date Title
ZA201900856B (en) Systems and methods for enhanced detection and quantification of analytes
EP3443485A4 (de) Systeme und verfahren zur bestimmung von interessenpunkten
EP3552137A4 (de) System und verfahren zur erkennung von cryptoware
EP3215712A4 (de) Akustische klassifizierung und quantifizierung von bohrlochlecks
EP3262166A4 (de) Durch bindung ausgelöste, transkriptionelle schaltungen und verfahren zur verwendung davon
EP3194594A4 (de) Probenverarbeitungssysteme mit hohem durchsatz und verfahren zur verwendung
EP3414327A4 (de) Nachweis von nukleinsäuren
EP3280325A4 (de) Nachweis von neurologischen erkrankungen und verfahren zur verwendung davon
EP3155640A4 (de) Probenanalysesystem und verfahren zur verwendung
EP3341711A4 (de) Systeme und verfahren für den multiplex-nachweis von biomarkern
EP3691626A4 (de) Verfahren zum nachweis von transthyretin
HK1243489A1 (zh) 用於檢測分析物的方法和系統
EP3697499A4 (de) Nachweis von symmetrischem dimethylarginin
EP3292395A4 (de) Verfahren und systeme zum nachweis von analyten
EP3177327A4 (de) Inhibitoren von myh7b und verwendungen davon
EP3372686A4 (de) Biomarker für den nachweis von lungenadenokarzinom und verwendung davon
GB201718352D0 (en) Devices and methods for detection of biomarkers
EP3141601A4 (de) Doppel-carbonylreduktasemutant und verwendung davon
EP3311142A4 (de) Nachweis von liquor
EP3521805A4 (de) Verfahren zur detektion von partikeln auf einer platte
EP3254126A4 (de) Störungsdetektion und dekonvolution eines bestimmten spitzenwerts
EP3120144A4 (de) Vorrichtung zur erkennung von krankheitszuständen und verwendungen davon
EP3537951A4 (de) Verbesserte erkennung von flüssigkeitsveränderungen
EP3377631A4 (de) Verfahren und materialien zur sensitiven detektion von zielmolekülen
EP3194563A4 (de) Verfahren zur partiellen lyse und test

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20190311

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/53 20060101AFI20200702BHEP

Ipc: C07K 7/14 20060101ALI20200702BHEP

Ipc: C07K 9/00 20060101ALI20200702BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20201014

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 9/00 20060101ALI20201008BHEP

Ipc: C07K 7/14 20060101ALI20201008BHEP

Ipc: G01N 33/53 20060101AFI20201008BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20230503

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230516