EP3448348A1 - Dispositif et procédé pour distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif - Google Patents

Dispositif et procédé pour distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif

Info

Publication number
EP3448348A1
EP3448348A1 EP17717751.6A EP17717751A EP3448348A1 EP 3448348 A1 EP3448348 A1 EP 3448348A1 EP 17717751 A EP17717751 A EP 17717751A EP 3448348 A1 EP3448348 A1 EP 3448348A1
Authority
EP
European Patent Office
Prior art keywords
housing
clutch transmission
strip
drive wheel
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP17717751.6A
Other languages
German (de)
English (en)
Other versions
EP3448348B1 (fr
Inventor
Marc BLOMENKEMPER
Michael Linn
Ronald Hackbarth
Markus Bee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Priority claimed from PCT/EP2017/059374 external-priority patent/WO2017186562A1/fr
Publication of EP3448348A1 publication Critical patent/EP3448348A1/fr
Application granted granted Critical
Publication of EP3448348B1 publication Critical patent/EP3448348B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0053—Syringes, pipettes or oral dispensers

Definitions

  • the invention relates to a device for dispensing active ingredient or drug-carrying strip with a housing in which a coil chamber for receiving a drug-containing or drug-carrying band is arranged, in which a gear train is mounted with a driven roller for conveying the tape and in which a separating device for separating the Strip is arranged from the belt and a method for dispensing active ingredient-carrying or drug-carrying strip with such a device, wherein between the driven roller and the pressure roller, a drug-containing or drug-carrying band is arranged.
  • the present invention is based on the problem, a
  • the gearbox is preceded by a clutch transmission.
  • the clutch transmission has a manually actuable release element.
  • the output roller can be driven in incremental steps by means of the clutch transmission.
  • Shifting the clutch transmission couples a movement of the
  • Trigger element with the rotation of a drive wheel, so that the drive wheel rotates by a defined angle of rotation.
  • the drive wheel transmits the
  • the angle of rotation of the drive wheel is one unit or an integer multiple of this one unit.
  • FIG. 15 tripping device
  • FIG. 16 dosing device
  • FIG. 17 drive wheel
  • FIG. 18 separating device
  • FIG. 19 Alternative embodiment of a device for the
  • Another embodiment of a device for dispensing strips with a rotatable trigger element is Another embodiment of a device for dispensing strips with a rotatable trigger element.
  • Figures 1 - 5 show a first embodiment of a device (10) for dispensing strips.
  • Such devices (10) are used to deliver a precise dose of a drug, e.g. Insulin, to the user or to a patient.
  • a drug e.g. Insulin
  • the device (10) comprises a housing (11) in which a
  • the housing (11) has at least approximately the shape of a cylindrical disc with a bottom (13) and a Top (14).
  • the longitudinal direction (15) is defined below as normal to the flat region of the lower side (13) and the upper side (14).
  • a switch button (91) is arranged at the bottom (13) as a triggering and actuating element (91) at the bottom (13) as a triggering and actuating element (91) at the bottom (13) as a triggering and actuating element (91) a switch button (91) is arranged.
  • the switch button (91) - ie on its upper side (14) - the housing (11) has a protruding hood (18).
  • the unactuated device (10) is thus at least approximately symmetrical to its central transverse plane.
  • a discharge area (17) arranged on the peripheral surface (16) of the housing (11) is closed in the representation of FIG. 1 by means of a protective flap (68).
  • this is a self-wound oral drug film having active pharmaceutical agents on its active agent-containing film layer.
  • the strips produced therefrom are e.g. applied to the oral mucosa.
  • This coil can be rotatably mounted on a housing-fixed bobbin.
  • the band (221) has a constant cross section over its length.
  • the free end (222) of the band (221) points in the direction of the output area (17).
  • the band (221) is protected in the coil chamber (12) from dust, moisture, UV light, other environmental influences and damage.
  • the drive device (71) comprises a gear transmission (121) and a clutch transmission (72) upstream of this.
  • the gear train (121) has a driven roller (154) mounted in the housing (11), which is loaded by means of a pressure roller (158).
  • the pressure roller (158) may be spring-loaded in the direction of the driven roller (154).
  • Between the output roller (154) and the rotatably mounted pressure roller (158) is the band (221) in the
  • Output roller (154) for this purpose has a cylindrically shaped rolling surface (156), whose longitudinal length (15) oriented length corresponds to the length of the pressure roller (158). For example, it slightly protrudes on both sides of the belt (221).
  • the pressure roller (158) may be made of an elastic material, eg rubber.
  • the rolling surface (156) of the driven roller (154) can be made of this material.
  • the driven roller (154) has a second rolling area (157) which is arranged coaxially with the rolling surface (156) and offset in the longitudinal direction (15).
  • This Wälz Scheme (157) is formed in the embodiment as a spur gear. Its diameter is for example one third larger than the diameter of the rolling surface (156). The gearing of the second
  • Rolling area (157) may be e.g. as a degree or helical toothing, as
  • the output roller (154) is driven at its rolling area (157) by means of a drive wheel (122).
  • the output roller (154) and the drive wheel (122) parallel to each other
  • the diameter of the drive wheel (122) is two and a half times the diameter of the Wälz Schemes (157).
  • the drive wheel (122) has a toothing in the exemplary embodiment, which meshes with the toothing of the rolling area (157).
  • This gear stage can also be designed as a friction gear stage, bevel gear stage, as a worm and worm wheel, etc.
  • Axes (123, 155, 159) may be arranged along a common straight line.
  • the output roller (154)
  • the drive wheel (122) has a central hub (124), a web (125) with openings (126) and a circumferential Wälzbund (127).
  • Breakthroughs (126) to reduce the moment of inertia are evenly distributed in the web (125).
  • the drive wheel (122) is mounted, for example, on an upper housing part (51) arranged in the housing pin (52) in the axial and radial directions.
  • a driver (128) is arranged, which is integrally formed, for example, on the hub (124).
  • the driver (128) is hook-shaped and protrudes approximately radially out of the hub (124).
  • the hub (124) has e.g. five takers (131). These have a constant over their length
  • Gearbox (121) upstream clutch transmission (72) It is also conceivable to arrange the driving grooves on the switching pinion (74) and to connect the engaging drivers to the driving wheel (122), e.g. to mold.
  • the shift clutch transmission (72) further comprises the shift key (91) and a shift spring (73).
  • the switching button (91), the switching spring (73) and the switching pinion (74) are arranged coaxially with each other.
  • the switching spring (73) and the switching pinion (74) are guided in the longitudinal direction (15) along the upper shell housing pin (52).
  • the stroke of the shift pinion (74) in the longitudinal direction (15) is limited by means of a recess (55) of the upper shell housing pin (52).
  • the switching pinion (74) is cup-shaped in the embodiment. It has an internal spring retainer (75) and e.g. five outboard
  • the spring receptacle (75) is cylindrical and has a front end a support ring (77). This support ring (77) has a central
  • the thickness of the Wegritzels (74) in the region of the switching pin (76) is twice the thickness of the hub (124).
  • This shaft-hub connection is formed in the exemplary embodiment as a splined connection. But it can also be designed as a positive, axially movable coupling in the design of a polygonal profile, serrated profile, feather key or another rigid connection.
  • buttons (79) are limited. Each level of each one of these
  • Button (79) closes with a normal plane to the longitudinal axis (15) an angle of e.g. 45 degrees.
  • an angle of e.g. 45 degrees In the exemplary embodiment is the single
  • buttons (79) additionally inclined by an angle of 15 degrees, so that the bordering on the envelope surface of the button (79) further in the direction of the housing lower part (31) than the adjacent to the cylindrical part of the limit of the button (79).
  • the switching pinion (74) may also be formed with buttons (79) whose radials are oriented parallel to a normal plane of the longitudinal direction (15).
  • the switching spring (73) is arranged, which is supported in the hub (124) of the drive wheel (122).
  • the spring element (73) forming the switching spring (73) is designed, for example, as a cylindrical helical spring in the form of a compression spring. It has a constant winding cross-section and a constant wire thickness over its length. It is also conceivable to form the spring element (73) with a non-constant winding cross-section and / or non-constant wire thickness in order to
  • the switching pinion (74) with the switching button (91) forms a releasable form-locking clutch.
  • the switch button (91) has, for example, ten arranged along a guide cylinder (92)
  • Switchboard guide webs (93). Each of these switch guide ribs (93) has a switch guide surface (94) which is complementary to a
  • Each switch button guide surface (94) is limited by means of a free surface (95) oriented in the longitudinal direction (15), which is designed as a radial surface of the guide cylinder (92).
  • the ring-shaped end face (96) of the trigger element (91) has an interrupted sawtooth profile.
  • the triggering element (91) also has two guide openings (97) lying opposite one another, in which, for example, guide pins (34) fastened in the housing (11) are guided. These prevent rotation of the switch button (91) relative to the housing (11) and a loss of the
  • Switch buttons (91) In the housing (11), the switch button (91) is guided along a lower housing guide tube (35).
  • the minimum stroke of the switch button (91) in the longitudinal direction (15) corresponds in the embodiment of twice the width of its switch button guide surface (94).
  • This width of the switching-button guide surface (94) is the length of the secant of the envelope surface in the region of the switch-guide ribs (93) measured in plan view in a normal plane to the longitudinal axis (15).
  • Shifter guide surface (94) with a normal plane to
  • the minimum stroke is twice the said width multiplied by the tangent of the angle between the switchboard guide surface (94) and the normal plane.
  • a switch contact guide web (93) is arranged in each case between two guide tube ribs (37). It is also conceivable to make the buttons (79) of the switching pinion (74) wider than described above. For example, they can sweep over a 36 degree segment to cover a switch guide surface (94) and an end abutment surface (36) of the guide tube (35).
  • the switch button (91) has an external one
  • Actuator head (98) with a e.g. convex arched actuating surface.
  • the switch button (91) can additionally be fitted against the housing (11) e.g. be sealed by a flexible sealing element to prevent the ingress of
  • Prevent contamination This can be designed, for example, elastically deformable.
  • the driver (128) of the drive wheel (22) meshes with a
  • Ratchet wheel (211) This is rotatably mounted on the upper shell (51) of the housing (11) on a pivot pin. Every time the drive wheel (122) rotates, the detent wheel (211) becomes a sawtooth-shaped one
  • the detent wheel (211) On the side facing the inner wall of the upper shell (51), the detent wheel (211) has, for example, a colored segment-like marking (213).
  • the housing (11) has in his
  • Upper shell (51) has a viewing window (53) through which the detent wheel (211) is visible.
  • the mark (213) forms a
  • Residual quantity indicator If it becomes visible, the band (221) or - if the device is not refillable (10) - the device (10) to be replaced.
  • the coil (223) wound band (221) is freely rotatably mounted.
  • the coil (223) may also be on a housing side
  • the separating device (161) has a camshaft (162), a
  • Camshaft (162) for example, fixed to the pivot shaft (165) of the housing (11) pivotally mounted protective flap (68).
  • the protective flap (68) In the illustration of Figure 2 when opening the protective flap (68) the
  • the pivot angle of the protective flap (68) from the closed to the open position is for example 90 degrees.
  • the camshaft (162) has a
  • camshaft (162) is also conceivable to form the camshaft (162) only with a half cam.
  • the half-cam then connects the cylinder-section-shaped region (163) with the cam tip region (164) on only one side.
  • the camshaft (162) with two mutually in
  • the locking slide (201) has a slide portion (202), a compression spring portion (203) and a bending spring portion (204). In the exemplary embodiment, it is displaceably mounted in the lower shell (31) in the radial direction to the center line of the clutch transmission (72).
  • Slider portion (202) may be wedge-shaped at its free end.
  • the locking slide (201) is shown in the figure 3
  • Compression spring region (203) has an actuating rod (205), which with
  • the rhombus-shaped webs (206) is connected.
  • the bending spring region (204) arranged transversely thereto comprises two bending webs (207), which surround, for example, housing-side spring pins (38).
  • the rod-shaped formed slide portion (202) is in an opening (39) of the
  • Locking slide (201) is moved in the direction of the locking position. Here, both the webs (206) and the bending spring area (204) are elastically deformed.
  • the slide rod (202) is moved into the switch-button recess (41) and engages there behind the actuating head (98) of the
  • the swing frame (171) is formed in the embodiment U-shaped. It is mounted on the shaft of the driven pulley (154). For storage, it has two frame arms (172) which engage around the output roller (154) at their end faces. At the freely projecting ends of the frame arms (172) each have a return spring (173) is arranged. These trained as bending springs
  • Return springs (173) support the rear end of the swing frame in the conveying direction (225) on a housing-side support pin (19).
  • the free ends of the frame arms (172) abut, for example, on the camshaft (162) or have a small distance to this.
  • Camshaft (162), which is coupled to the pivot frame (171) can have a different angular position than the region of the camshaft (162) which couples with the locking slide (201).
  • Swing frame (174) includes a knife holder (175) and a
  • the knife holder (175) consists for example of a rigid holder with a transverse receiving groove for receiving the
  • Cutting edge (178) points in the illustrations of Figures 2 and 3 upwards.
  • the hold-down (179) has two spaced-apart, elastically deformable hold-down bending springs (181, 182). These are aligned parallel to the cutting blade (177).
  • the first hold-down bending spring (181) situated at the rear in the conveying direction (225) has the same distance from the cutting blade (177) as the second hold-down bending spring (182) located at the front in the conveying direction (225).
  • both hold-down bending springs (181, 182) are spaced from the belt (221).
  • a strip-guiding element (42) is arranged in the housing (11) . This is between the driven roller (154) and the first hold-down bending spring (181). On the holding-down bending springs (181, 182) facing away from the band (221), a counter-holder (21) is arranged.
  • the pivot pin is set so that it engages behind the detent wheel (211).
  • the drive wheel (122) On the upper shell housing pin (52), the drive wheel (122)
  • the pressure roller (158) is used in the cup-shaped housing cap (61). Furthermore, the camshaft (162) in the cup-shaped housing cap (61), the pressure roller (158) is used. Furthermore, the camshaft (162) in the cup-shaped housing cap (61), the pressure roller (158) is used. Furthermore, the camshaft (162) in the cup-shaped housing cap (61), the pressure roller (158) is used. Furthermore, the camshaft (162) in the cup-shaped housing cap (61), the pressure roller (158) is used. Furthermore, the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (162) in the camshaft (16
  • This Drivekantwelle (165) has two storage areas (166), with which it is mounted in the housing cap (61). Outside the bearing areas (166), the polygonal shaft (165) has, for example, hexagonal pins (167) which project out of the housing cap (61) on both sides after insertion.
  • the protective flap (68) is placed, so that the protective flap (68) positively engages the hexagonal pin (167).
  • the lower shell (31) with the components arranged therein and the upper shell (51) with the components arranged therein are joined together.
  • the joining may be solvable, e.g. by means of a snap connection or insoluble, e.g. done by means of an adhesive bond.
  • the housing cap (61) with the built-in components with the composite of the lower shell (31) and the upper shell (51) is joined. This joint connection can be made detachable or insoluble.
  • the assembly of the individual subassemblies and the entire device (10) can also be done in a different order. It is also conceivable to assign individual components to other subassemblies. For example, all gear parts in the lower shell (31) may be pre-assembled, so that the upper shell (51) forms a device cover. With such a construction, the device (10) can be easily tested before closing.
  • FIG. 10 shows the upper shell (51) upwards.
  • the lower shell (31) lies in the palm of the hand.
  • the protective flap (68) is closed.
  • To operate the operator presses the switch button (91) relative to the housing (11) in the direction of the upper shell (51).
  • the clutch transmission (72) is operated.
  • the switch button (91) moves the shift pinion (74) against the force of the compression spring (73) in the longitudinal direction (15) relative to the housing (11).
  • Figure 6 shows the clutch transmission (72) schematically before the operation.
  • the guide tube ribs (37) are hatched.
  • the switch guide webs (93) are at the top and the switch pins (76) of the shift ratchet (74) are shown below.
  • the buttons (79) of the shift ratchet (74) abut the shift button guide surfaces (94).
  • the end abutment surfaces (36) of the lower housing guide tube (35) are aligned with the right next to the adjacent switch guide surfaces (94).
  • Clutch transmission (72) is positively secured.
  • FIG. 7 shows the shift clutch transmission with displaced shift pinion (74).
  • the clutch transmission (72) is disengaged.
  • Triggering element (91) acting force of the switching spring (73) has a
  • This component causes a rotation of the switching pinion (74) in the illustration of Figure 7 to the right.
  • the shift pinion (74) slides along the switchboard guide surface (94), relaxing the compression spring (73).
  • the rotating shift pinion (74) takes over the switching pin (76) the
  • Drive wheel (122) with.
  • the drive wheel (122) rotates clockwise.
  • the drive wheel (122) drives the output roller (154), which rotates counterclockwise.
  • the output roller (154) pulls over the
  • the shift pinion (74) rotates until it rests against the next switchgear web (93), cf. Figure 8.
  • the shift pinion (74) in addition to the housing-side end abutment surface (36) strike.
  • the switch button return spring (99) causes the switch button (91) to move out relative to the switch button (91)
  • buttons (79) of the Wegritzels (74) now slide - loaded by the relaxing compression spring (73) - on the contact surface (36) and the
  • the shift pinion (74) continues to rotate the drive wheel (122) which continues to convey the belt (221) by means of the driven pulley (154).
  • Locking slide (201), the last described above conveying step can be triggered.
  • the hold-down device (179) pivots against the counter-holder (21) and holds the band (221) firmly by means of the hold-down bending springs (181, 182).
  • the tape (221) or the strip in the output area can not be
  • Clutch transmission (72) is the conveying of the belt (221) in only one direction possible.
  • the strip (221) can be conveyed further in the direction of the dispensing area (17) in order to remove further strips.
  • the remainder quantity display (213) the level of the belt can be monitored.
  • a new band (221) can be used in a detachably joined housing (11) - after consumption of the belt (221).
  • the trigger element (91) is actuated several times before the protective flap (68) is opened.
  • the protective flap (68) may for example be transparent and have a scale.
  • the user receives, for example, an acoustic and haptic signal.
  • FIG. 10 shows a bottom view of a further device (10). This has at least approximately the shape of an equilateral prism.
  • the structure of the drive device (71) corresponds to the structure of the first
  • the switch button (91) on the underside (3) of the housing (11) is arranged.
  • Figures 11-18 show a further embodiment of a
  • This device (10) for dispensing strips of a medicated or active substance-carrying band (221). This device (10) has a
  • Dosing device (231) are arranged.
  • the housing (11) has a flat upper side (14) and an underside (13) arranged parallel thereto.
  • the longitudinal direction (15) is defined below as normal to the upper side (14) and to the lower side (13).
  • the device (10) has a handle (22), a
  • the drive device (71) has a clutch transmission (72) and a gearbox (121) connected downstream of the clutch transmission (72).
  • the release lever (91) is mounted, for example, on a housing pin (32).
  • the on the lower shell (31) integrally formed housing pin (32) may be cylindrical or formed, for example, with three stages.
  • the release lever (91) is mounted, for example, on the uppermost stage.
  • the release lever (91) is about a longitudinal axis (15) oriented pivot axis (23) of that shown in Figures 11 to 13
  • a return spring (99) fixed in the housing (11) and the release lever (91) is e.g. elastically deformed in the design of a torsion spring.
  • the release lever (91) has a handle lever (101) and a knife holder lever (102), between which the pivot bearing (103) is arranged.
  • the outwardly projecting handle lever (101) has 1.9 times the length of the within the
  • Knife holder lever (102) and the handle lever (101) in the illustration of Figure 12 form an angle of 165 degrees.
  • the release lever (91) has in the handle lever (101) within the housing (11) a radially to the pivot axis (23) arranged latching guide (104).
  • latching guide (104) In this latching guide (104) a compression spring (105) is arranged, the one
  • Locking element (106) is wedge-shaped and is in the direction of
  • the handle lever (101) At its free end protruding from the housing (11), the handle lever (101) has a handle (109).
  • the length of the handle (109) in the longitudinal direction (15) corresponds for example to the length of the housing (11) in this direction, reduced by twice the wall thickness.
  • the handle (109) is cup-shaped, wherein the bending line is displaced parallel to the longitudinal direction (15) relative to the handle (109) in the direction of the discharge area (17).
  • the knife holder lever (102) has a driving pin (111) protruding in the longitudinal direction (15) from the knife holder lever (102).
  • This driving pin (111) is connected to a pivot frame (171) of
  • a metering device (231) is arranged behind the triggering element (91). This comprises a metering lever (232) which is adjustable between the minimum position shown in this figure and a maximum position.
  • the metering lever (232) is mounted on the housing pin (32).
  • Housing pin (32) is the metering lever (232), for. stored at the middle level. For example, it can be adjusted by a swivel angle of 63 degrees.
  • the metering lever (232) has a metering slide (233) protruding from the housing (11), which is e.g. along a housing side
  • Locking rail (24) gradually adjustable from the minimum position to the maximum position, for example, in six stages.
  • the metering slide (233) can also be infinitely adjustable. For example, it can be a detachable
  • the metering device (231) may be designed such that the metering slide (233) is connected to the metering lever (232) only during assembly.
  • Metering lever (232) a guide shell (234).
  • the guide shell (234) covers in the exemplary embodiment a sector of 83 degrees, whose
  • Latching element (106) on the guide shell (234) is supported.
  • the guide shell (234) on the right side has an insertion bevel (236).
  • the drive wheel (122) on the housing pin (32) rotatably arranged.
  • the drive wheel (122) is mounted, for example, on the lowest storage stage.
  • the drive wheel (122) is in Embodiment a cup-shaped cylindrical wheel with a
  • the internal toothing (133) is a driving toothing with e.g.
  • the groove base (138) is formed concave.
  • the latching teeth (135) each have an insertion bevel (141) adjacent to the latching tooth head (139) on the right-hand side.
  • the distance between the latching tooth flanks (137), for example, is slightly larger than the width of the latching element (106) of the release lever (91).
  • the diameter of the head circle defined by the locking tooth heads (139) is greater by a few tenths of a millimeter than twice the radius of the outer surface of the guide shell (234).
  • the normal plane oriented in the longitudinal direction (15) encloses an angle of two degrees in the middle of a groove base (138) with a radial plane. In the illustration of Figure 12, this angle is oriented to the right.
  • the groove base (138) can also be formed coaxially with the longitudinal axis (15) oriented axis of rotation of the drive wheel (122). The limiting the latching tooth gap (136)
  • Latching tooth flanks (137) are then formed, for example, parallel to this radial plane.
  • the external toothing (134) of the drive wheel (122) is a
  • Involute toothing (134) It can be straight or oblique.
  • the drive wheel (122) meshes with an intermediate gear (151) mounted in the housing (11) and having toothing of the same module.
  • the intermediate gear (151) of the three wheels (122, 151, 154) existing, designed as Wälzgetriebe gear train (121) carries in the embodiment offset from each other two gears (152, 153).
  • the second toothing (153) is coupled to the output roller (154).
  • the two toothings (152, 153) have the same pitch circle and, for example, identical modules, so that the envelope contour of the
  • insects (151) is a cylinder jacket surface. It is also conceivable to arrange the entire Wälzgetriebe (121) in a transmission plane.
  • the Gearing (152; 153) of the intermediate gear (151) then meshes both with the drive wheel (122) and with the toothing of the output roller (154). It is also conceivable to design the toothings (152, 153) of the intermediate gear (151) with different pitch circles and / or with different modules.
  • the output roller (54) and the pressure roller (158) are formed in this embodiment as described in connection with the first embodiment.
  • the separating device (161) comprises a swiveling frame (171) mounted pivotably in the housing (11), in which a holding-down device (179) and a separating tool (177) are held.
  • the swing frame (171) has a pivot hub (183) which engages in the installed state in the longitudinal direction (15) oriented housing-side pivot pin.
  • a radially directed to the longitudinal direction (15) pivoting web (184) points in the direction of
  • the pivot web (184) surrounds the pressure roller (158).
  • the pivot web (184) has a guide slot (185) which receives the driving pin (111) of the release lever (91).
  • the e.g. embossed guide cusp (185) has four sections (186 - 189) which together form a polygon.
  • a first e.g. Wedge-shaped lift section (186) has a constant depth. He closes
  • FIGS 12 and 18 In the basic position of the driving pin (111) sits at the apex of this angle.
  • the lifting section (186) is, for example, on its underside, see. Figure 18, open.
  • a freewheeling section (187) is connected to the lifting section (186).
  • This, for example, arcuate portion (187) is concentric with the pivot hub (183) and leads in the illustrations of Figures 12 and 18 upwards.
  • the freewheeling section (187) it is also conceivable to form the freewheeling section (187) as a wide, eg straight groove.
  • the depth the freewheeling section (187) corresponds to the depth of the lifting section (186), but it may also be formed deeper.
  • Adjoining the freewheeling section (187) is a return stroke section (188) which, for example, has the same depth as the lifting section (186) and the
  • Freewheel section (187).
  • the pivot web (184) is designed to be open at the top in the region of the return stroke section (188).
  • the fourth section (189) is an e. wedge-shaped
  • Guide section (189) which connects the return stroke section (188) with the lifting section (186) at least in the region of the apex. For example, the backdrop reason in the guide section (189) increases from
  • Guide portion (189) may also be formed narrower than shown. Another embodiment of the guide slot (185) is conceivable.
  • the swing frame (171) has a return pivot spring (173). This is for example designed as a projecting leaf spring and in the
  • the separating tool (177) is arranged at the output region (17) facing side of the swing frame (171).
  • the cutting tool (177) is a longitudinally (15) and transversely to the conveying direction (225) oriented cutting blade (177). In the illustrations of FIGS. 12 and 18, it protrudes downwardly out of the swing frame (171).
  • the cutting blade (177) is surrounded by a hold-down (179) which is spring loaded in the pivot frame (171) is arranged.
  • the hold-down device (179) is a rectangular frame which is arranged in the longitudinal direction (15) and transversely to the conveying direction (225) and which is displaceably mounted in the swivel frame (171).
  • the hold-down (179) in the vertical direction parallel to the cutting blade (177) is displaceable.
  • it is loaded by means of a swivel frame (171) arranged leaf spring (192).
  • Embodiment a drug-carrying or drug-containing band (221) arranged.
  • this is designed as the im
  • the housing (11) has a housing lower part (31), a housing cover (51) and a housing cap (61) pivotally formed therewith.
  • Housing base (31) is trough-shaped. She is wearing her
  • Inner wall all pivots for the gear train (121) and the housing pin (32) for the clutch transmission (72).
  • Housing cap (61) inserted into the lower shell (31), so that the two parts relative to each other about a pivot pin (62) are pivotable.
  • Housing cap (61) and the lower housing part (31) may also be integrally formed.
  • the drive wheel (122) is inserted, wherein the locking teeth (135) in the illustration of Figure 12 show upward.
  • the metering device (231) On the housing pin (32) then the metering device (231)
  • the mold shell (234) in the drive wheel (122) and the metering lever (232) rests against the housing (11).
  • the intermediate gear (151) and the driven roller (154) are mounted and optionally secured against displacement in the longitudinal direction (15).
  • the pressure roller (158) is mounted in the housing cap (61). This can be in
  • the driving pin (111) of the release lever (91) is located after installation in the lifting section (186) of the sliding guide (185).
  • the handle (109) protrudes to the outside. In this state, for example, the function of the dispenser device (10) can be tested.
  • the housing cover (51) is placed. Another order of assembly is conceivable.
  • the operator grips the housing (11) on the handle (22) and places his fingers on the handle (109) of the
  • Triggering element (91) When triggered, the handle (109) in the
  • the return spring (99) is tensioned.
  • the locking element (106) slides along the guide shell (234). As soon as the latching element (106) has left the right-hand end of the guide shell (234), it engages, positively loaded by the compression spring (105), in a latching tooth gap (136) of the drive wheel (122).
  • Clutch transmission (72) is now engaged.
  • the drive wheel (122) Upon further actuation of the trigger element (91) the drive wheel (122) is taken.
  • the drive wheel (122) drives the driven pulley (154) via the intermediate gear (151), which conveys the belt (221) in the conveying direction (225).
  • the conveying takes place until the release lever (91) has an e. G. housing-side stop abuts.
  • the driving pin (111) is moved from right to left along the lifting section (186) of the sliding guide (185) in the illustration of FIG.
  • the swing frame (171) is raised, whereby the return pivot spring (173) is loaded.
  • the driving pin (111) lies in the freewheeling section (187).
  • the swing frame (171) accelerated by the return pivot spring (173), in the starting position pivoted back.
  • the hold-down (179) hits the belt (221) and secures the position of the belt (221) against the counter-holder (21).
  • Deformation of the hold-down spring (192) strikes the cutting blade (177) on the belt (221) and cuts through it.
  • the cut-off portion lies in the discharge area (17) and is held by means of the hold-down (179).
  • the release lever (91) is moved back after releasing the handle (109) by means of the relaxing return spring (99) in the direction of the starting position shown in Figure 12. This slides the
  • the guide shell (234) is pivoted in the illustration of Figure 12 clockwise about the housing pin (32).
  • the drive wheel (122) Upon actuation of the release lever (91) engages the locking element (106) already after overcoming a smaller sector in the drive wheel (122). Until the release lever (91) reaches the housing stop, the drive wheel (122) is rotated by a greater angle of rotation than in the example described above.
  • the length of the conveyed belt (221) and the strip produced is proportional to this angle of rotation of the drive wheel (122). This can be the maximum dose of the strip can be adjusted so that overdose is prevented.
  • FIG. 19 shows a further variant of such a device (10).
  • the triggering element (91) is designed as a large-surface switching switch (91), which is arranged laterally on the housing (10). Opposite the trigger element (91) of the metering slide (233) is arranged.
  • the internal structure and function of this device (10) correspond to the structure and function of the device (10) described in the embodiment of FIGS. 11-18.
  • Figures 20-26 show another device (10) for dispensing strips made from a drug-bearing or drug-carrying band (221).
  • the housing (10) consists in this example of a
  • a trigger element (91) is arranged and at the bottom (13) a cap (18).
  • the triggering element (91) designed as a rotary knob (91) may e.g. Have recessed grips.
  • the device (10) has a toggle button (241), which is actuated for separating a strip.
  • the longitudinal direction (15) is also in this
  • Embodiment defined normal to the top (14) and bottom (13).
  • a drive device (71) a clutch transmission (72) and a gear train (121).
  • the clutch transmission (72) driven by means of the triggering element (91) drives the gearbox (121).
  • the gear train (121) conveys the belt (221) the bobbin chamber (12) in the direction of the discharge area (17). After actuation of the toggle button (241), a strip separated from the strip (221) can be removed.
  • a display (252) visible, indicating, for example, the number of subsidized since the last separation units of the belt (221).
  • the knob (91) is rotatably mounted in the housing (11). He has e.g. four driving lugs (113) which engage in a hub (124) of a drive wheel (122) and engage behind.
  • the drive wheel (122) in turn is coupled by means of driving pins (142) with a cup-shaped ratchet wheel (81).
  • the ratchet wheel (81) is displaceable relative to the drive wheel (122) in the longitudinal direction (15).
  • Mit supportiveuten (84) into which the driving pins (142) of the drive wheel (122) engage. It has at its the rotary knob (91) facing away from the bottom (83) has a circumferential sawtooth toothing (82) in a corresponding
  • Switching spring (73) arranged in the form of a compression spring (73), so that the two components are always pressed apart.
  • An axial bearing of the rotary knob (91) in the housing (11) secures the position of the drive wheel (122) in the longitudinal direction (15).
  • the ratchet wheel (81) is moved from a stable position in which it is positively coupled and locked with the lower shell (31) in a labile position. If the knob (91) is released, turn the knob
  • Sawtooth gearing (45, 82) switches the clutch transmission (72).
  • the ratchet wheel (81) engages in the next notch of the counter-toothing (45) a positive fit.
  • the clutch transmission (72) is thus gradually advanced.
  • the device can also from the bottom (13) of the
  • Housing (11) are actuated from.
  • the cap (8) is designed as a knob and connected by means of a torsionally rigid coupling with the other components of the clutch transmission (72).
  • the cap (18) is rotated clockwise.
  • the drive wheel (122) has, for example, an external spur gear toothing (134) which is coupled in a gear train (121) to the output roller (154) by means of a intermediate wheel (151).
  • the intermediate gear (151), the driven roller (154) and the toothings may be formed as described in connection with the previous embodiments.
  • the use of a friction gear is conceivable.
  • the device (10) can also be designed without intermediate wheel (151).
  • Ratchet wheel (81) and the housing lower part (31) in the other direction rotating the
  • a counter-pressure roller (158) is arranged in the housing cap (61) of the housing (11). This is for example designed as the counter-pressure roller (158) described in connection with the previous embodiments.
  • the separating device (161) has an in a plan view L-shaped pivot frame (171) having a hold-down (179) and a
  • Separating tool (177) carries.
  • Separating tool (177) are for example formed as in
  • the pivotal frame (171) shown in an isometric bottom view in FIG. 26 has a pivot hub (183) for receiving a housing-side pivot pin (62) and a recess (193) for
  • Swing frame (171) a guide slot (185). This is, for example, similar to that formed in connection with the guide slot (185) described in FIG. The vertex position is in this illustration at the left end of the guide slot (185).
  • the lift section (186), the freewheel section (187) and the return stroke section (188) are groove-shaped.
  • the guide portion (189) is formed like a ramp.
  • the swing frame (171) is loaded by means of a return pivot spring (173) in the form of a torsion spring in the direction of a cutting position. In the illustration of FIG. 22, the pivoting frame (171) is concealed by a guide element (63) of the housing (11).
  • the toggle button (241) is pivotally mounted. It forms the actuating element of the separating device (161).
  • the toggle button (241) is designed like a lever.
  • On one side of the pivot axis (242) has a tilt stop (243) which limits the pivot angle of the toggle button (241) relative to the housing (11).
  • the toggle button (241) has a handle portion (244), which protrudes on the output side (17) from the housing (11). The operator can move the toggle switch (241) from a rest position to an operating position by pressing the grip area (244) in the direction of the housing (11). In addition, a return spring, the toggle button (241) from the operating position in the
  • the toggle button (241) has a driving pin (245) which, in the illustration of FIG. 21, slides into the guide slot (185) of the
  • Swing frame (171) engages.
  • In the illustrated rest position of the driving pin (245) is at the apex of the guide slot (185).
  • Swing frame (171) is spaced in this position to the belt (221). at a depression of the toggle button (241) moves the driving pin (245) along the lifting portion (186) of the guide slot (185). The swing frame (171) is raised against the force of the return pivot spring (173). As soon as the driving pin (245) reaches the freewheeling section (187), the separating device (161) is accelerated in the direction of the belt (221) by means of the return pivoting spring (173). After severing a strip, the toggle button (241) is pivoted back into the starting position, for example, by means of a spring. The driving pin (245) migrates along the
  • the intermediate gear (151) drives a payer (251).
  • the counter (251) has a gear segment formed Zählradsegment (253), the one
  • Counter drum (254) with the display (252) drives and a
  • Decoupling device (261) When turning the intermediate wheel (151), the counting drum (254) is further rotated by one drum segment. Here, as a torsion spring (256) formed return spring (256) is stretched. In the exemplary embodiment, the counting drum (254) can be further extended from the starting position by a maximum of five drum segments. Then that blocks
  • a cylinder jacket section with the tip circle radius of the gear segment (253) circumferentially bounds the gear segment (253) on both sides.
  • the drum segments are for example by a
  • the decoupling device (261) is coupled to the toggle button (241). It comprises a fork rod (262) which is pivotally mounted on the toggle button (241).
  • the fork rod (262) has two fork arms (263) whose free ends are each formed as a shaft receptacle (264).
  • counter (251) is additionally held.
  • the fork arms (263) can be performed, for example, on the housing (11) in a linear guide.
  • the counter (251) may also be coupled to the drive wheel (122) or to the output roller (154).
  • Wheels gear (121) inserted into the housing lower part (31). Also, the toggle button (241) with the decoupling device (261) and the band (221) are inserted into the housing lower part (31).
  • Ratchet coupling (81, 31) for the operator acoustically and haptically
  • the drive wheel (122) drives by means of
  • the counter (251) indicates that a portion of the tape (221), e.g. a unit dose, has been promoted. If a strip of greater length to be generated, the knob (91) is rotated again. The counter (251) continues to count.
  • the maximum length of the strip - and thus the maximum drug dose - is limited by the blocking of the gear train (121) by means of the gear segment (253).
  • the toggle button (241) is pressed, bringing the
  • Separating device (161) is actuated.
  • the separated strip is held by means of the separating device (161) and can now be removed.
  • FIG. 27 shows a further embodiment of such a device (10).
  • the knob (91) is on a side surface of the
  • Housing (11) arranged and has recessed grips (112).
  • Tilting button (241) is arranged on an end face below the dispensing area (17). At a further, for example, adjacent to the two aforementioned surfaces arranged surface sits the viewing window (64) for the counter (251).

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un dispositif permettant de distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif, ledit dispositif comportant un boîtier dans lequel est aménagée une chambre de bobine destinée à recevoir une bande contenant un principe actif ou servant de substrat à un principe actif et dans laquelle est logé un organe de commande à roues doté d'un rouleau mené pour transporter la bande et dans laquelle est disposé un dispositif de séparation pour séparer les bandelettes de la bande, ainsi qu'un procédé pour distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif avec un dispositif de ce type, une bande contenant un principe actif ou servant de substrat à un principe actif étant disposée entre le rouleau mené et le rouleau d'appui. Un organe de commande à accouplement de séparation est monté en amont de l'organe de commande à roues. L'organe de commande à accouplement de séparation présente un élément déclencheur pouvant être actionné manuellement. Le rouleau mené peut être entraîné au moyen de l'organe de commande à accouplement de séparation dans des étapes incrémentielles. La présente invention permet de mettre au point un dispositif et un procédé permettant de distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif, qui présentent pour l'essentiel la même dose de principe actif.
EP17717751.6A 2016-04-26 2017-04-20 Dispositif et procede de distribution de bandes contenant ou supportant un agent actif Active EP3448348B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2016167074 2016-04-26
PCT/EP2017/059374 WO2017186562A1 (fr) 2016-04-26 2017-04-20 Dispositif et procédé pour distribuer des bandelettes contenant un principe actif ou servant de substrat à un principe actif

Publications (2)

Publication Number Publication Date
EP3448348A1 true EP3448348A1 (fr) 2019-03-06
EP3448348B1 EP3448348B1 (fr) 2024-10-16

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EP17717751.6A Active EP3448348B1 (fr) 2016-04-26 2017-04-20 Dispositif et procede de distribution de bandes contenant ou supportant un agent actif

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