EP3372666A4 - DEVICE AND MICROFLUIDIC SYSTEM FOR THE INVESTIGATION OF CELL CULTURES - Google Patents

DEVICE AND MICROFLUIDIC SYSTEM FOR THE INVESTIGATION OF CELL CULTURES Download PDF

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Publication number
EP3372666A4
EP3372666A4 EP16861659.7A EP16861659A EP3372666A4 EP 3372666 A4 EP3372666 A4 EP 3372666A4 EP 16861659 A EP16861659 A EP 16861659A EP 3372666 A4 EP3372666 A4 EP 3372666A4
Authority
EP
European Patent Office
Prior art keywords
cell cultures
microfluidic system
studying cell
studying
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16861659.7A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3372666A1 (en
Inventor
Luis J. FERNÁNDEZ LEDESMA
Rosa MONGE PRIETO
Guillermo LLAMAZARES PRIETO
José María AYUSO DOMÍNGUEZ
María VIRUMBRALES MUÑOZ
Jorge Santolaria Mazo
Ignacio OCHOA GARRIDO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Zaragoza
Centro de Investigacion Biomedica en Red CIBER
Centro Investigacion Biomedica en Red CIBER
Original Assignee
Universidad de Zaragoza
Centro de Investigacion Biomedica en Red CIBER
Centro Investigacion Biomedica en Red CIBER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Zaragoza, Centro de Investigacion Biomedica en Red CIBER, Centro Investigacion Biomedica en Red CIBER filed Critical Universidad de Zaragoza
Publication of EP3372666A1 publication Critical patent/EP3372666A1/en
Publication of EP3372666A4 publication Critical patent/EP3372666A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16861659.7A 2015-11-06 2016-11-04 DEVICE AND MICROFLUIDIC SYSTEM FOR THE INVESTIGATION OF CELL CULTURES Pending EP3372666A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201531607A ES2615512B1 (es) 2015-11-06 2015-11-06 Dispositivo y sistema microfluídico para el estudio de cultivos celulares
PCT/ES2016/070782 WO2017077163A1 (es) 2015-11-06 2016-11-04 Dispositivo y sistema microfluídico para el estudio de cultivos celulares

Publications (2)

Publication Number Publication Date
EP3372666A1 EP3372666A1 (en) 2018-09-12
EP3372666A4 true EP3372666A4 (en) 2019-07-03

Family

ID=58662920

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16861659.7A Pending EP3372666A4 (en) 2015-11-06 2016-11-04 DEVICE AND MICROFLUIDIC SYSTEM FOR THE INVESTIGATION OF CELL CULTURES

Country Status (4)

Country Link
US (1) US11142734B2 (es)
EP (1) EP3372666A4 (es)
ES (1) ES2615512B1 (es)
WO (1) WO2017077163A1 (es)

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Publication number Priority date Publication date Assignee Title
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
JP6930914B2 (ja) 2014-10-29 2021-09-01 コーニング インコーポレイテッド 灌流バイオリアクタ・プラットフォーム
SG11201703493SA (en) 2014-10-29 2017-05-30 Corning Inc Cell culture insert
ES2679721B1 (es) 2017-01-18 2019-06-21 Univ Zaragoza Generador de aerosoles nanoparticulados y procedimiento de generacion de aerosoles en continuo asociado a dicho generador
EP3652290B1 (en) 2017-07-14 2022-05-04 Corning Incorporated 3d cell culture vessels for manual or automatic media exchange
WO2019014636A1 (en) 2017-07-14 2019-01-17 Corning Incorporated CONTAINER FOR CELL CULTURE
JP7195302B2 (ja) 2017-07-14 2022-12-23 コーニング インコーポレイテッド ３ｄ培養のための細胞培養容器及び３ｄ細胞の培養方法
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
CN112449604B (zh) 2018-02-19 2023-05-26 萨拉戈萨大学 用作有结核感染风险的患者的预防剂或用作治疗结核感染患者的辅助剂的组合物
US12110479B2 (en) * 2018-06-11 2024-10-08 The University Of Chicago Microfluidic devices, systems, and methods for investigating three-dimensional cellular structures
WO2020005150A1 (en) * 2018-06-29 2020-01-02 Johan Kreuger Biofilm culturing
CN111032851B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 具有包含液体介质传递表面的侧壁的微腔皿
EP3649229B1 (en) 2018-07-13 2021-08-25 Corning Incorporated Cell culture vessels with stabilizer devices
JP7171696B2 (ja) * 2018-07-13 2022-11-15 コーニング インコーポレイテッド 相互接続されたウェルを有するマイクロプレートを備えた流体デバイス
ES2738926A1 (es) 2018-07-26 2020-01-27 Univ Zaragoza Granulisina, metodo de obtencion y usos
CZ2020134A3 (cs) * 2020-03-12 2021-05-19 Univerzita Jana Evangelisty Purkyně V Ústí Nad Labem Mikrofluidní čip pro průtokové kultivace biologických objektů
CN111349560A (zh) * 2020-03-16 2020-06-30 西北工业大学 一种具有自放大功能的微流控细胞培养芯片
NL2025320B1 (en) * 2020-04-09 2021-10-25 Univ Twente Fluidic device, cell culturing system and method of testing a compound
JP7543710B2 (ja) * 2020-06-04 2024-09-03 ウシオ電機株式会社 マイクロ流体デバイス
TWI751902B (zh) * 2021-01-29 2022-01-01 錢家琪 細胞培養平台及其製造方法
JP2024517400A (ja) * 2021-04-16 2024-04-22 プレクシアム・インコーポレイテッド 分析装置用キャップ
US20230146860A1 (en) * 2021-04-23 2023-05-11 Massachusetts Institute Of Technology Fluidic platforms for perfusable vascularized tissues with infiltrates

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120003732A1 (en) * 2005-07-07 2012-01-05 CellASIC, INC. Microfluidic cell culture systems
WO2014210207A1 (en) * 2013-06-25 2014-12-31 University Of Washington Through Its Center For Commercialization Self-digitization of sample volumes

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DK1773978T3 (da) * 2004-05-19 2014-05-26 Univ Pittsburgh Perfunderede, tredimensionelle celle/vævssygdomsmodeller
WO2006089354A1 (en) * 2005-02-23 2006-08-31 M.B.T.L. Limited Culture device
EP2318505A1 (en) * 2008-08-01 2011-05-11 Smart Biosystems APS A chamber of a bioreactor platform
ES2795974T3 (es) * 2013-09-05 2020-11-25 Univ Bern Dispositivo para el modelado in vitro de tejidos in vivo de órganos
JP6195992B2 (ja) * 2014-08-05 2017-09-13 ヤマハ発動機株式会社 対象物の保持装置
ES2734803T3 (es) 2015-06-16 2019-12-12 Centro De Investig Biomedica En Red Ciber Método para el diagnóstico/pronóstico de la escoliosis idiopática del adolescente
WO2017077135A1 (en) 2015-11-05 2017-05-11 Centro De Investigación Biomédica En Red Process of gene-editing of cells isolated from a subject suffering from a metabolic disease affecting the erythroid lineage, cells obtained by said process and uses thereof.
ES2626237B1 (es) 2015-12-22 2018-05-03 Universidad De Zaragoza Sistema electrónico de potencia modular variable para la generación de pulsos eléctricos y usos asociados
ES2679721B1 (es) 2017-01-18 2019-06-21 Univ Zaragoza Generador de aerosoles nanoparticulados y procedimiento de generacion de aerosoles en continuo asociado a dicho generador

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120003732A1 (en) * 2005-07-07 2012-01-05 CellASIC, INC. Microfluidic cell culture systems
WO2014210207A1 (en) * 2013-06-25 2014-12-31 University Of Washington Through Its Center For Commercialization Self-digitization of sample volumes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KIM JIN-YOUNG ET AL: "3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis", JOURNAL OF BIOTECHNOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 205, 12 January 2015 (2015-01-12), pages 24 - 35, XP029240257, ISSN: 0168-1656, DOI: 10.1016/J.JBIOTEC.2015.01.003 *
See also references of WO2017077163A1 *

Also Published As

Publication number Publication date
US20180327701A1 (en) 2018-11-15
US11142734B2 (en) 2021-10-12
ES2615512B1 (es) 2018-03-15
ES2615512A1 (es) 2017-06-07
EP3372666A1 (en) 2018-09-12
WO2017077163A1 (es) 2017-05-11

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