EP3060648A4 - Systems, devices and methods for microfluidic culturing, manipulation and analysis of tissues and cells - Google Patents
Systems, devices and methods for microfluidic culturing, manipulation and analysis of tissues and cells Download PDFInfo
- Publication number
- EP3060648A4 EP3060648A4 EP14855429.8A EP14855429A EP3060648A4 EP 3060648 A4 EP3060648 A4 EP 3060648A4 EP 14855429 A EP14855429 A EP 14855429A EP 3060648 A4 EP3060648 A4 EP 3060648A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- manipulation
- tissues
- cells
- analysis
- systems
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361894298P | 2013-10-22 | 2013-10-22 | |
PCT/US2014/061782 WO2015061458A1 (en) | 2013-10-22 | 2014-10-22 | Systems, devices and methods for microfluidic culturing, manipulation and analysis of tissues and cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3060648A1 EP3060648A1 (en) | 2016-08-31 |
EP3060648A4 true EP3060648A4 (en) | 2017-05-31 |
Family
ID=52993507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14855429.8A Withdrawn EP3060648A4 (en) | 2013-10-22 | 2014-10-22 | Systems, devices and methods for microfluidic culturing, manipulation and analysis of tissues and cells |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3060648A4 (en) |
CA (1) | CA2927947A1 (en) |
WO (1) | WO2015061458A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2852672C (en) | 2011-10-17 | 2021-07-20 | Massachusetts Institute Of Technology | A microfluidic system and method for delivering a payload into a cell by causing perturbations in a cell membrane of the cell |
KR102530914B1 (en) | 2013-08-16 | 2023-05-11 | 메사추세츠 인스티튜트 오브 테크놀로지 | Selective delivery of material to cells |
CA2964392A1 (en) | 2014-10-31 | 2016-05-06 | Massachussetts Institute Of Technology | Delivery of biomolecules to immune cells |
EP3218492A4 (en) | 2014-11-14 | 2018-10-10 | Massachusetts Institute Of Technology | Disruption and field enabled delivery of compounds and compositions into cells |
EP3245294A4 (en) | 2015-01-12 | 2018-05-30 | Massachusetts Institute of Technology | Gene editing through microfluidic delivery |
EP4257675A3 (en) | 2015-07-09 | 2024-01-03 | Massachusetts Institute of Technology | Delivery of materials to anucleate cells |
US20180327706A1 (en) * | 2015-10-19 | 2018-11-15 | The Methodist Hospital | Crispr-cas9 delivery to hard-to-transfect cells via membrane deformation |
WO2017197343A2 (en) * | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic on-chip filters |
EP3556845A1 (en) * | 2018-04-20 | 2019-10-23 | Cellix Limited | A method and device for transfecting cells |
WO2021216005A1 (en) * | 2020-04-22 | 2021-10-28 | Agency For Science, Technology And Research | A device for studying interactions of a first cell type with a second cell type and related method |
CN113522383B (en) * | 2021-06-25 | 2023-02-24 | 东南大学 | Cell working condition device |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011014674A2 (en) * | 2009-07-29 | 2011-02-03 | Cornell University | Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof |
US20110136162A1 (en) * | 2009-08-31 | 2011-06-09 | Drexel University | Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers |
WO2012048269A2 (en) * | 2010-10-08 | 2012-04-12 | Chander Ashok C | Systems, methods and devices for measuring growth/oncogenic & migration/metastatic potential |
US20130143230A1 (en) * | 2011-12-02 | 2013-06-06 | The Trustees Of The Stevens Institute Of Technology | Microfluidic-based cell-culturing platform and method |
WO2013082612A1 (en) * | 2011-12-03 | 2013-06-06 | Emd Millipore Corporation | Micro-incubation systems for microfluidic cell culture and methods |
US20130224853A1 (en) * | 2008-12-11 | 2013-08-29 | Joule Unlimited Technologies, Inc. | Solar Biofactory, Photobioreactors, Passive Thermal Regulation Systems And Methods for Producing Products |
-
2014
- 2014-10-22 WO PCT/US2014/061782 patent/WO2015061458A1/en active Application Filing
- 2014-10-22 EP EP14855429.8A patent/EP3060648A4/en not_active Withdrawn
- 2014-10-22 CA CA2927947A patent/CA2927947A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130224853A1 (en) * | 2008-12-11 | 2013-08-29 | Joule Unlimited Technologies, Inc. | Solar Biofactory, Photobioreactors, Passive Thermal Regulation Systems And Methods for Producing Products |
WO2011014674A2 (en) * | 2009-07-29 | 2011-02-03 | Cornell University | Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof |
US20110136162A1 (en) * | 2009-08-31 | 2011-06-09 | Drexel University | Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers |
WO2012048269A2 (en) * | 2010-10-08 | 2012-04-12 | Chander Ashok C | Systems, methods and devices for measuring growth/oncogenic & migration/metastatic potential |
US20130143230A1 (en) * | 2011-12-02 | 2013-06-06 | The Trustees Of The Stevens Institute Of Technology | Microfluidic-based cell-culturing platform and method |
WO2013082612A1 (en) * | 2011-12-03 | 2013-06-06 | Emd Millipore Corporation | Micro-incubation systems for microfluidic cell culture and methods |
Non-Patent Citations (1)
Title |
---|
See also references of WO2015061458A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2927947A1 (en) | 2015-04-30 |
WO2015061458A1 (en) | 2015-04-30 |
EP3060648A1 (en) | 2016-08-31 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20160511 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20170428 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12M 3/04 20060101ALI20170421BHEP Ipc: C12M 1/00 20060101ALI20170421BHEP Ipc: B81C 1/00 20060101ALI20170421BHEP Ipc: C12M 3/08 20060101ALI20170421BHEP Ipc: C12N 5/09 20100101ALI20170421BHEP Ipc: C12M 3/02 20060101AFI20170421BHEP Ipc: C12M 1/34 20060101ALI20170421BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20171128 |