EP3060648A4 - Systèmes, dispositifs et procédés pour la culture, la manipulation et l'analyse microfluidiques de tissus et de cellules - Google Patents

Systèmes, dispositifs et procédés pour la culture, la manipulation et l'analyse microfluidiques de tissus et de cellules Download PDF

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Publication number
EP3060648A4
EP3060648A4 EP14855429.8A EP14855429A EP3060648A4 EP 3060648 A4 EP3060648 A4 EP 3060648A4 EP 14855429 A EP14855429 A EP 14855429A EP 3060648 A4 EP3060648 A4 EP 3060648A4
Authority
EP
European Patent Office
Prior art keywords
manipulation
tissues
cells
analysis
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14855429.8A
Other languages
German (de)
English (en)
Other versions
EP3060648A1 (fr
Inventor
Ashok C. Chander
Wendell R. SU
Thiagarajan MEYYAPPAN
Jonathan VARSANIK
Senthil Ramu
Michael MANAK
Brad HOGAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellanyx Diagnostics LLC
Original Assignee
Cellanyx Diagnostics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellanyx Diagnostics LLC filed Critical Cellanyx Diagnostics LLC
Publication of EP3060648A1 publication Critical patent/EP3060648A1/fr
Publication of EP3060648A4 publication Critical patent/EP3060648A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
EP14855429.8A 2013-10-22 2014-10-22 Systèmes, dispositifs et procédés pour la culture, la manipulation et l'analyse microfluidiques de tissus et de cellules Withdrawn EP3060648A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361894298P 2013-10-22 2013-10-22
PCT/US2014/061782 WO2015061458A1 (fr) 2013-10-22 2014-10-22 Systèmes, dispositifs et procédés pour la culture, la manipulation et l'analyse microfluidiques de tissus et de cellules

Publications (2)

Publication Number Publication Date
EP3060648A1 EP3060648A1 (fr) 2016-08-31
EP3060648A4 true EP3060648A4 (fr) 2017-05-31

Family

ID=52993507

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14855429.8A Withdrawn EP3060648A4 (fr) 2013-10-22 2014-10-22 Systèmes, dispositifs et procédés pour la culture, la manipulation et l'analyse microfluidiques de tissus et de cellules

Country Status (3)

Country Link
EP (1) EP3060648A4 (fr)
CA (1) CA2927947A1 (fr)
WO (1) WO2015061458A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113337402A (zh) 2011-10-17 2021-09-03 麻省理工学院 细胞内传递
CN105848793B (zh) 2013-08-16 2019-03-05 麻省理工学院 材料选择性的递送至细胞
US11111472B2 (en) 2014-10-31 2021-09-07 Massachusetts Institute Of Technology Delivery of biomolecules to immune cells
CN107002089B (zh) 2014-11-14 2021-09-07 麻省理工学院 化合物和组合物向细胞中的破坏和场实现的递送
WO2016115179A1 (fr) 2015-01-12 2016-07-21 Massachusetts Institute Of Technology Édition de gène par administration microfluidique
JP6925984B2 (ja) 2015-07-09 2021-08-25 マサチューセッツ インスティテュート オブ テクノロジー 無核細胞への物質の送達
EP3365269A4 (fr) * 2015-10-19 2019-06-19 The Methodist Hospital Distribution, par déformation membranaire, de crispr-cas9 à des cellules difficiles à transfecter
WO2017197343A2 (fr) * 2016-05-12 2017-11-16 10X Genomics, Inc. Filtres microfluidiques sur puce
EP3556845A1 (fr) * 2018-04-20 2019-10-23 Cellix Limited Procédé et dispositif de transfection de cellules
US20230221299A1 (en) * 2020-04-22 2023-07-13 Agency For Science, Technology And Research A device for studying interactions of a first cell type with a second cell type and related method
CN113522383B (zh) * 2021-06-25 2023-02-24 东南大学 细胞工况化装置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011014674A2 (fr) * 2009-07-29 2011-02-03 Cornell University Dispositif microfluidique pour l’étude pharmacocinétique – pharmacodynamique de médicaments et ses utilisations
US20110136162A1 (en) * 2009-08-31 2011-06-09 Drexel University Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers
WO2012048269A2 (fr) * 2010-10-08 2012-04-12 Chander Ashok C Systèmes, procédés et dispositifs pour mesurer le potentiel de croissance/oncogène et migratoire/métastatique
US20130143230A1 (en) * 2011-12-02 2013-06-06 The Trustees Of The Stevens Institute Of Technology Microfluidic-based cell-culturing platform and method
WO2013082612A1 (fr) * 2011-12-03 2013-06-06 Emd Millipore Corporation Systèmes de micro-incubation pour culture cellulaire microfluidique et procédés associés
US20130224853A1 (en) * 2008-12-11 2013-08-29 Joule Unlimited Technologies, Inc. Solar Biofactory, Photobioreactors, Passive Thermal Regulation Systems And Methods for Producing Products

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130224853A1 (en) * 2008-12-11 2013-08-29 Joule Unlimited Technologies, Inc. Solar Biofactory, Photobioreactors, Passive Thermal Regulation Systems And Methods for Producing Products
WO2011014674A2 (fr) * 2009-07-29 2011-02-03 Cornell University Dispositif microfluidique pour l’étude pharmacocinétique – pharmacodynamique de médicaments et ses utilisations
US20110136162A1 (en) * 2009-08-31 2011-06-09 Drexel University Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers
WO2012048269A2 (fr) * 2010-10-08 2012-04-12 Chander Ashok C Systèmes, procédés et dispositifs pour mesurer le potentiel de croissance/oncogène et migratoire/métastatique
US20130143230A1 (en) * 2011-12-02 2013-06-06 The Trustees Of The Stevens Institute Of Technology Microfluidic-based cell-culturing platform and method
WO2013082612A1 (fr) * 2011-12-03 2013-06-06 Emd Millipore Corporation Systèmes de micro-incubation pour culture cellulaire microfluidique et procédés associés

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2015061458A1 *

Also Published As

Publication number Publication date
EP3060648A1 (fr) 2016-08-31
WO2015061458A1 (fr) 2015-04-30
CA2927947A1 (fr) 2015-04-30

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