EP3286296A4 - Structure cellulaire microfluidique - Google Patents

Structure cellulaire microfluidique Download PDF

Info

Publication number
EP3286296A4
EP3286296A4 EP16783924.0A EP16783924A EP3286296A4 EP 3286296 A4 EP3286296 A4 EP 3286296A4 EP 16783924 A EP16783924 A EP 16783924A EP 3286296 A4 EP3286296 A4 EP 3286296A4
Authority
EP
European Patent Office
Prior art keywords
cell culture
microfluidic cell
microfluidic
culture
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16783924.0A
Other languages
German (de)
English (en)
Other versions
EP3286296A1 (fr
Inventor
Randall D. LOWE, Jr.
Kristin BEAUMONT
Aathavan KARUNAKARAN
Natalie MARKS
Jason M. MCEWEN
Mark P. White
J. Tanner Nevill
Gang F. WANG
Andrew W. Mcfarland
Daniele Malleo
Keith J. Breinlinger
Xiao GUAN
Kevin T. Chapman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phenomex Inc
Original Assignee
Berkeley Lights Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berkeley Lights Inc filed Critical Berkeley Lights Inc
Priority claimed from PCT/US2016/028808 external-priority patent/WO2016172454A1/fr
Publication of EP3286296A1 publication Critical patent/EP3286296A1/fr
Publication of EP3286296A4 publication Critical patent/EP3286296A4/fr
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/16Microfluidic devices; Capillary tubes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/20Material Coatings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16783924.0A 2015-04-22 2016-04-22 Structure cellulaire microfluidique Pending EP3286296A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562151325P 2015-04-22 2015-04-22
PCT/US2016/028808 WO2016172454A1 (fr) 2015-04-22 2016-04-22 Structure cellulaire microfluidique

Publications (2)

Publication Number Publication Date
EP3286296A1 EP3286296A1 (fr) 2018-02-28
EP3286296A4 true EP3286296A4 (fr) 2019-01-09

Family

ID=58055846

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16783924.0A Pending EP3286296A4 (fr) 2015-04-22 2016-04-22 Structure cellulaire microfluidique

Country Status (4)

Country Link
EP (1) EP3286296A4 (fr)
CN (2) CN114085730A (fr)
HK (1) HK1253068A1 (fr)
TW (2) TWI819383B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3576814A4 (fr) * 2017-01-31 2020-02-19 Alphinity, LLC Récipients de biotraitement à pompe intégrée
CN108485972B (zh) * 2018-03-28 2021-06-25 东南大学 一种用于细胞组织培养与实时监测的微流控芯片及其使用方法
AU2019301819B2 (en) * 2018-07-12 2023-01-12 Berkeley Lights, Inc. Screening plant protoplasts for disease resistant traits
EP3962652A4 (fr) 2019-04-30 2023-01-18 Berkeley Lights, Inc. Procédés d'encapsulation et d'analyse de cellules
WO2021038996A1 (fr) * 2019-08-29 2021-03-04 ファナック株式会社 Dispositif de production de cellule et méthode de production de cellule
CA3155946A1 (fr) * 2019-10-25 2021-04-29 Angel Navas ANGELES Systemes permettant de faire fonctionner des dispositifs microfluidiques
JP7339138B2 (ja) * 2019-12-02 2023-09-05 株式会社日立製作所 細胞培養装置
US20220348863A1 (en) * 2021-04-28 2022-11-03 A.U. Vista, Inc. Tft-based cell isolation device and cell manipulation panel thereof
CN113996355B (zh) * 2021-10-28 2023-06-06 上海浚真生命科学有限公司 取样装置
TWI832371B (zh) * 2022-08-10 2024-02-11 醫華生技股份有限公司 生物微粒培養設備及其微結構
CN117262436B (zh) * 2023-11-21 2024-01-26 山东大学齐鲁医院 一种肿瘤切片存储装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060226012A1 (en) * 2005-04-08 2006-10-12 Kanagasabapathi Thirukumaran T Integrated microfluidic transport and sorting system
WO2015188171A1 (fr) * 2014-06-06 2015-12-10 Berkeley Lights, Inc. Isolation de structures microfluidiques et piégeage de bulles
WO2016090295A1 (fr) * 2014-12-05 2016-06-09 The Regents Of The University Of California Dispositif microfluidique simple face, actionné par la lumière, à terre à mailles intégrée

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TW550066B (en) * 2000-12-01 2003-09-01 Ind Tech Res Inst Micro bio-cultivation device
US6982165B2 (en) * 2001-09-24 2006-01-03 Intel Corporation Nucleic acid sequencing by raman monitoring of molecular deconstruction
US6972173B2 (en) * 2002-03-14 2005-12-06 Intel Corporation Methods to increase nucleotide signals by raman scattering
US6984485B2 (en) * 2002-04-23 2006-01-10 Beckman Coulter, Inc. Polymer-coated substrates for immobilization of biomolecules and cells
US7790443B2 (en) * 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
US20080257735A1 (en) * 2004-09-24 2008-10-23 Regents Of The University Of California Microfluidic Device for Enabling the Controlled Growth of Cells and Methods Relating to Same
US20060252087A1 (en) * 2005-01-18 2006-11-09 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US8475886B2 (en) * 2005-08-05 2013-07-02 Corning Incorporated Methods for producing surfaces that resist non-specific protein binding and cell attachment
US8148111B2 (en) * 2006-03-17 2012-04-03 Sanyo Chemical Industries, Ltd. Cell culture carrier comprising poly(meth)acrylic (salt) particle and artificial polypeptide
KR100903969B1 (ko) * 2007-06-12 2009-06-25 삼성전자주식회사 마이크로 어레이, 마이크로 어레이용 기판 및 이들의 제조방법
CN101275114A (zh) * 2008-04-22 2008-10-01 北京大学 一种微流细胞培养阵列及其应用
TW201144805A (en) * 2010-06-08 2011-12-16 Academia Sinica Microfluidic device
CN102296029B (zh) * 2010-06-28 2013-01-30 裴国献 灌注式生物反应器系统
CN103889556A (zh) * 2011-01-06 2014-06-25 Gpb科学有限责任公司 在引入亲和性和大小两者的微流体芯片上的循环肿瘤细胞捕获
US9656874B2 (en) * 2011-01-11 2017-05-23 Nippon Sheet Glass Company, Limited Method for producing metal oxide-containing particles, and method for producing aggregates of metal oxide colloidal particles
WO2012109068A2 (fr) * 2011-02-11 2012-08-16 Corning Incorporated Surface polymère de libération de cellule pouvant être clivée par une enzyme
JP6122388B2 (ja) * 2011-02-28 2017-04-26 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 細胞培養システム
TWI438273B (zh) * 2011-03-08 2014-05-21 Univ Chang Gung High-throughput perfusative microfluidic cell culture wafers for miniaturized three-dimensional cell culture
TW201310016A (zh) * 2011-08-26 2013-03-01 Chin-Feng Wan 生物檢測晶片及其製造方法
US10626435B2 (en) * 2012-03-28 2020-04-21 Northeastern University Nanofluidic device for isolating, growing, and characterizing microbial cells
US9857333B2 (en) * 2012-10-31 2018-01-02 Berkeley Lights, Inc. Pens for biological micro-objects
CN204079986U (zh) * 2014-05-30 2015-01-07 南京农业大学 一种用于细胞迁移研究的微纳流控器件

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060226012A1 (en) * 2005-04-08 2006-10-12 Kanagasabapathi Thirukumaran T Integrated microfluidic transport and sorting system
WO2015188171A1 (fr) * 2014-06-06 2015-12-10 Berkeley Lights, Inc. Isolation de structures microfluidiques et piégeage de bulles
WO2016090295A1 (fr) * 2014-12-05 2016-06-09 The Regents Of The University Of California Dispositif microfluidique simple face, actionné par la lumière, à terre à mailles intégrée

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016172454A1 *

Also Published As

Publication number Publication date
HK1253068A1 (zh) 2019-06-06
TWI819383B (zh) 2023-10-21
TWI744230B (zh) 2021-11-01
TW202233824A (zh) 2022-09-01
TW201643241A (zh) 2016-12-16
CN114085730A (zh) 2022-02-25
EP3286296A1 (fr) 2018-02-28
CN107849505B (zh) 2021-09-07
CN107849505A (zh) 2018-03-27

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