EP3122180A4 - Appareil pour conservation de c urs prélevés pour la transplantation - Google Patents

Appareil pour conservation de c urs prélevés pour la transplantation Download PDF

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Publication number
EP3122180A4
EP3122180A4 EP15767752.7A EP15767752A EP3122180A4 EP 3122180 A4 EP3122180 A4 EP 3122180A4 EP 15767752 A EP15767752 A EP 15767752A EP 3122180 A4 EP3122180 A4 EP 3122180A4
Authority
EP
European Patent Office
Prior art keywords
transplanting
maintenance
harvested hearts
hearts
harvested
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15767752.7A
Other languages
German (de)
English (en)
Other versions
EP3122180B1 (fr
EP3122180A1 (fr
Inventor
Darren FREED
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tevosol Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP22158589.6A priority Critical patent/EP4023066A1/fr
Publication of EP3122180A1 publication Critical patent/EP3122180A1/fr
Publication of EP3122180A4 publication Critical patent/EP3122180A4/fr
Application granted granted Critical
Publication of EP3122180B1 publication Critical patent/EP3122180B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0273—Transport containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
    • A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3625—External stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3968—Constructional arrangements, e.g. casings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Agricultural Machines (AREA)
EP15767752.7A 2014-03-26 2015-03-18 Appareil pour conservation de c urs prélevés pour la transplantation Active EP3122180B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22158589.6A EP4023066A1 (fr) 2014-03-26 2015-03-18 Appareil pour conserver des c urs prélevés pour la transplantation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461970532P 2014-03-26 2014-03-26
PCT/CA2015/050201 WO2015143552A1 (fr) 2014-03-26 2015-03-18 Appareil pour conservation de cœurs prélevés pour la transplantation

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP22158589.6A Division EP4023066A1 (fr) 2014-03-26 2015-03-18 Appareil pour conserver des c urs prélevés pour la transplantation
EP22158589.6A Division-Into EP4023066A1 (fr) 2014-03-26 2015-03-18 Appareil pour conserver des c urs prélevés pour la transplantation

Publications (3)

Publication Number Publication Date
EP3122180A1 EP3122180A1 (fr) 2017-02-01
EP3122180A4 true EP3122180A4 (fr) 2018-01-03
EP3122180B1 EP3122180B1 (fr) 2022-05-11

Family

ID=54193814

Family Applications (2)

Application Number Title Priority Date Filing Date
EP15767752.7A Active EP3122180B1 (fr) 2014-03-26 2015-03-18 Appareil pour conservation de c urs prélevés pour la transplantation
EP22158589.6A Pending EP4023066A1 (fr) 2014-03-26 2015-03-18 Appareil pour conserver des c urs prélevés pour la transplantation

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP22158589.6A Pending EP4023066A1 (fr) 2014-03-26 2015-03-18 Appareil pour conserver des c urs prélevés pour la transplantation

Country Status (8)

Country Link
US (2) US10327442B2 (fr)
EP (2) EP3122180B1 (fr)
CN (2) CN106659150B (fr)
AU (1) AU2015234580B2 (fr)
BR (1) BR112016021971B1 (fr)
CA (2) CA3164819A1 (fr)
ES (1) ES2916212T3 (fr)
WO (1) WO2015143552A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
DK2704560T3 (da) 2011-04-14 2022-05-23 Transmedics Inc Organbehandlingsopløsning til maskinperfusion ex-vivo af donorlunger
US9706768B2 (en) 2012-01-17 2017-07-18 Darren Freed Apparatus for testing, assessment, and maintenance of harvested hearts for transplanting
CA3164819A1 (en) 2014-03-26 2015-10-01 Tevosol, Inc. Apparatus for maintenance of harvested hearts for transplanting
DK3151663T3 (da) 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
CA2970117A1 (fr) 2014-12-12 2016-06-16 Darren FREED Appareil et procede de perfusion d'organe
DE102016117901A1 (de) * 2016-09-22 2018-03-22 Technische Universität Dresden System und Verfahren zur extrakorporalen Perfusion von Organen
CA3097762A1 (fr) * 2017-04-21 2018-10-25 University Health Network Procede et systeme de perfusion cardiaque ex vivo
EP4252536A1 (fr) * 2022-04-01 2023-10-04 Medizinische Hochschule Hannover Système de perfusion

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070009881A1 (en) * 2003-09-03 2007-01-11 Joachim Arzt Perfusion circuit
US20070098694A1 (en) * 2005-10-28 2007-05-03 The United States Government by the Department of Veteran's Affairs Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant
EP3229588A1 (fr) * 2014-12-12 2017-10-18 Freed, Darren Appareil et procédé de perfusion d'organe

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WO1988005261A1 (fr) * 1987-01-16 1988-07-28 Tops Systems, Inc. Systeme de perfusion totale pour organes
US5157930A (en) 1991-04-22 1992-10-27 Mcghee Samuel C Organ preservation apparatus
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5338662A (en) 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
DE19535781C2 (de) 1995-09-26 1999-11-11 Fraunhofer Ges Forschung Vorrichtung zur aktiven Strömungsunterstützung von Körperflüssigkeiten
US5716378A (en) * 1996-06-06 1998-02-10 Medtronic, Inc. Heart preservation and transportation apparatus and method employing low rate cardiac pacing for improved removal of catabolites from the myocardium
US5807737A (en) 1996-07-26 1998-09-15 Schill Enterprises, Inc. Heart and lung support assembly
US6953655B1 (en) 1997-09-23 2005-10-11 The United States Of America As Represented By The Department Of Veterans Affairs Compositions, methods and devices for maintaining an organ
US8409846B2 (en) * 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6100082A (en) * 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
US6977140B1 (en) 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
EP1929863B1 (fr) * 1998-09-29 2016-11-09 Organ Recovery Systems, Inc. Appareil et procédé pour maintenir et/ou restaurer la viabilité d'organes
US7045279B1 (en) 1998-10-22 2006-05-16 Medtronic, Inc. Isolated perfused heart preparation and method of use
EP1181032A4 (fr) * 1999-04-14 2004-08-25 Breonics Inc Systeme support metabolique exsanguine d'un organe ou tissu
US6582375B2 (en) 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart
ES2885752T3 (es) 2003-04-04 2021-12-15 Organ Recovery Systems Inc Métodos y aparato para perfusión, diagnóstico, almacenamiento y/o transporte de un órgano o tejido
JP4444918B2 (ja) * 2003-05-15 2010-03-31 学校法人早稲田大学 脱細胞化方法及び生体組織処理装置
NL1024022C2 (nl) 2003-07-30 2005-02-01 Technologiestichting Stw Draagbare preservatie-inrichting voor een donororgaan.
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US20070048725A1 (en) * 2005-08-25 2007-03-01 Arrington Ben O'mar Machine perfusion of tissue grafts for transplantation
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WO2008100636A2 (fr) 2007-02-17 2008-08-21 President And Fellows Of Harvard College Compositions et procédé de conservation de tissu
JP5704818B2 (ja) 2007-03-01 2015-04-22 ライフライン サイエンティフィック インコーポレイテッド 潅流調節
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WO2010036726A1 (fr) 2008-09-23 2010-04-01 Cedars-Sinai Medical Center Procédés et appareil d'irrigation sanguine d'un cœur de donneur explanté
SE534527C2 (sv) 2009-09-24 2011-09-20 Vivoline Medical Ab Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning
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US9706768B2 (en) * 2012-01-17 2017-07-18 Darren Freed Apparatus for testing, assessment, and maintenance of harvested hearts for transplanting
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Publication number Priority date Publication date Assignee Title
US20070009881A1 (en) * 2003-09-03 2007-01-11 Joachim Arzt Perfusion circuit
US20070098694A1 (en) * 2005-10-28 2007-05-03 The United States Government by the Department of Veteran's Affairs Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant
EP3229588A1 (fr) * 2014-12-12 2017-10-18 Freed, Darren Appareil et procédé de perfusion d'organe

Non-Patent Citations (1)

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Title
See also references of WO2015143552A1 *

Also Published As

Publication number Publication date
AU2015234580A1 (en) 2016-10-27
ES2916212T3 (es) 2022-06-29
EP4023066A1 (fr) 2022-07-06
WO2015143552A1 (fr) 2015-10-01
AU2015234580B2 (en) 2018-11-15
CN113229273A (zh) 2021-08-10
CA3164819A1 (en) 2015-10-01
US20190387736A1 (en) 2019-12-26
CA2943633C (fr) 2023-06-20
BR112016021971A2 (fr) 2017-08-15
CA2943633A1 (fr) 2015-10-01
CN113229273B (zh) 2023-01-31
US10327442B2 (en) 2019-06-25
EP3122180B1 (fr) 2022-05-11
US20170223950A1 (en) 2017-08-10
BR112016021971B1 (pt) 2022-05-17
CN106659150B (zh) 2021-06-01
CN106659150A (zh) 2017-05-10
EP3122180A1 (fr) 2017-02-01

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