EP3065869A1 - Dispositif et procédé de manipulation de réactifs - Google Patents

Dispositif et procédé de manipulation de réactifs

Info

Publication number
EP3065869A1
EP3065869A1 EP14786497.9A EP14786497A EP3065869A1 EP 3065869 A1 EP3065869 A1 EP 3065869A1 EP 14786497 A EP14786497 A EP 14786497A EP 3065869 A1 EP3065869 A1 EP 3065869A1
Authority
EP
European Patent Office
Prior art keywords
chamber
fluid
supply line
membrane
fluidic supply
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14786497.9A
Other languages
German (de)
English (en)
Inventor
Thomas BRETTSCHNEIDER
Christian Dorrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP3065869A1 publication Critical patent/EP3065869A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Reciprocating Pumps (AREA)

Abstract

L'invention concerne un dispositif (10, 60), en particulier un dispositif microfluidique, servant à effectuer une analyse immunologique, comprenant des première, deuxième et troisième chambres (1, 2, 3) et une membrane (12). L'invention est caractérisée en ce que, lors d'une excursion donnée de la membrane (12) pénétrant dans la première chambre (1), un premier fluide (11) est guidé au moins partiellement de la première chambre (1) dans la deuxième chambre (2) de façon à déplacer au moins partiellement un second fluide (21) de la deuxième chambre (2) dans la troisième chambre (3) de sorte que la troisième chambre (3) est remplie avec le second fluide (21).
EP14786497.9A 2013-11-04 2014-10-16 Dispositif et procédé de manipulation de réactifs Withdrawn EP3065869A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102013222283.1A DE102013222283B3 (de) 2013-11-04 2013-11-04 Vorrichtung und Verfahren zur Handhabung von Reagenzien
PCT/EP2014/072245 WO2015062875A1 (fr) 2013-11-04 2014-10-16 Dispositif et procédé de manipulation de réactifs

Publications (1)

Publication Number Publication Date
EP3065869A1 true EP3065869A1 (fr) 2016-09-14

Family

ID=51752121

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14786497.9A Withdrawn EP3065869A1 (fr) 2013-11-04 2014-10-16 Dispositif et procédé de manipulation de réactifs

Country Status (5)

Country Link
US (1) US10562026B2 (fr)
EP (1) EP3065869A1 (fr)
CN (1) CN105682803B (fr)
DE (1) DE102013222283B3 (fr)
WO (1) WO2015062875A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201615320D0 (en) * 2016-09-09 2016-10-26 Invitron Ltd Point of care platform test
US20190240661A1 (en) 2016-10-07 2019-08-08 Boehringer Ingelheim Vetmedica Gmbh Cartridge and analysis system for testing a sample

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090185955A1 (en) * 2006-02-13 2009-07-23 Koninklijke Philips Electronics N.V. Microfluidic device for molecular diagnostic applications
EP2259072A1 (fr) * 2008-03-24 2010-12-08 NEC Corporation Mécanisme de commande de passage d'écoulement pour micropuce
US20120177543A1 (en) * 2005-11-30 2012-07-12 Micronics, Inc. Microfluidic reactor system

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293519A1 (fr) 1987-06-03 1988-12-07 James F. Brown Dispositif de commande d'écoulement dans des capillaires
DE3926066A1 (de) * 1989-08-07 1991-02-14 Ibm Deutschland Mikromechanische kompressorkaskade und verfahren zur druckerhoehung bei extrem niedrigem arbeitsdruck
US5580523A (en) * 1994-04-01 1996-12-03 Bard; Allen J. Integrated chemical synthesizers
JP4756835B2 (ja) * 2004-07-14 2011-08-24 キヤノン株式会社 生化学反応カートリッジ
US7832429B2 (en) 2004-10-13 2010-11-16 Rheonix, Inc. Microfluidic pump and valve structures and fabrication methods
US20060201425A1 (en) * 2005-03-08 2006-09-14 Applied Microstructures, Inc. Precursor preparation for controlled deposition coatings
CN102268367A (zh) * 2005-06-23 2011-12-07 拜欧卡蒂斯股份公司 用于自动医疗诊断的盒体、系统和方法
EP2002223A2 (fr) * 2006-03-29 2008-12-17 Koninklijke Philips Electronics N.V. Systeme de traitement de fluide et de determination de volume
US20080026373A1 (en) * 2006-07-26 2008-01-31 Rodionova Natalia A Assays Based On Light Emission From Analyte Complexes Within A Cassette
US20080260553A1 (en) * 2007-04-17 2008-10-23 Hsiao-Kang Ma Membrane pump device
US8100293B2 (en) * 2009-01-23 2012-01-24 Formulatrix, Inc. Microfluidic dispensing assembly
CA2786569C (fr) * 2010-01-29 2019-04-09 Micronics, Inc. Cartouche microfluidique «de l'echantillon au resultat»
DE102011077134A1 (de) 2011-06-07 2012-12-13 Robert Bosch Gmbh Kartusche, Zentrifuge sowie Verfahren zum Mischen einer ersten und zweiten Komponente
DE102011077101A1 (de) 2011-06-07 2012-12-13 Robert Bosch Gmbh Mikrofluidisches System und Verfahren zum Betreiben eines solchen Systems
DE102011078976A1 (de) * 2011-07-11 2013-01-17 Robert Bosch Gmbh Mikrofluidische Vorrichtung sowie Verfahren zur Herstellung einer mikrofluidischen Vorrichtung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120177543A1 (en) * 2005-11-30 2012-07-12 Micronics, Inc. Microfluidic reactor system
US20090185955A1 (en) * 2006-02-13 2009-07-23 Koninklijke Philips Electronics N.V. Microfluidic device for molecular diagnostic applications
EP2259072A1 (fr) * 2008-03-24 2010-12-08 NEC Corporation Mécanisme de commande de passage d'écoulement pour micropuce

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2015062875A1 *

Also Published As

Publication number Publication date
CN105682803A (zh) 2016-06-15
US10562026B2 (en) 2020-02-18
US20160263573A1 (en) 2016-09-15
WO2015062875A1 (fr) 2015-05-07
CN105682803B (zh) 2017-12-12
DE102013222283B3 (de) 2015-01-15

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