EP3004354A4 - Compositions et procédés permettant de moduler l'expression de foxp3 - Google Patents

Compositions et procédés permettant de moduler l'expression de foxp3 Download PDF

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Publication number
EP3004354A4
EP3004354A4 EP14807355.4A EP14807355A EP3004354A4 EP 3004354 A4 EP3004354 A4 EP 3004354A4 EP 14807355 A EP14807355 A EP 14807355A EP 3004354 A4 EP3004354 A4 EP 3004354A4
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EP
European Patent Office
Prior art keywords
compositions
methods
foxp3 expression
modulating
modulating foxp3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14807355.4A
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German (de)
English (en)
Other versions
EP3004354A1 (fr
Inventor
James Barsoum
Mariano SEVERGNINI
James Mcswiggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Translate Bio MA Inc
Original Assignee
RaNA Therapeutics Inc
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Filing date
Publication date
Application filed by RaNA Therapeutics Inc filed Critical RaNA Therapeutics Inc
Publication of EP3004354A1 publication Critical patent/EP3004354A1/fr
Publication of EP3004354A4 publication Critical patent/EP3004354A4/fr
Withdrawn legal-status Critical Current

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/323—Chemical structure of the sugar modified ring structure
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  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
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EP14807355.4A 2013-06-07 2014-06-06 Compositions et procédés permettant de moduler l'expression de foxp3 Withdrawn EP3004354A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361832677P 2013-06-07 2013-06-07
PCT/US2014/041345 WO2014197826A1 (fr) 2013-06-07 2014-06-06 Compositions et procédés permettant de moduler l'expression de foxp3

Publications (2)

Publication Number Publication Date
EP3004354A1 EP3004354A1 (fr) 2016-04-13
EP3004354A4 true EP3004354A4 (fr) 2017-01-11

Family

ID=52008624

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14807355.4A Withdrawn EP3004354A4 (fr) 2013-06-07 2014-06-06 Compositions et procédés permettant de moduler l'expression de foxp3

Country Status (7)

Country Link
US (1) US20160122760A1 (fr)
EP (1) EP3004354A4 (fr)
JP (1) JP2016521556A (fr)
KR (1) KR20160027968A (fr)
AU (1) AU2014274730A1 (fr)
CA (1) CA2914536A1 (fr)
WO (1) WO2014197826A1 (fr)

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US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
KR20150030205A (ko) 2012-05-16 2015-03-19 라나 테라퓨틱스, 인크. Smn 유전자 패밀리 발현을 조절하기 위한 조성물 및 방법
US10174323B2 (en) 2012-05-16 2019-01-08 The General Hospital Corporation Compositions and methods for modulating ATP2A2 expression
EA201492122A1 (ru) 2012-05-16 2015-10-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии utrn
AU2013262709A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating MECP2 expression
EP2850188A4 (fr) 2012-05-16 2016-01-20 Rana Therapeutics Inc Compositions et méthodes pour moduler l'expression de la famille multigénique de l'hémoglobine
CA2921459A1 (fr) 2013-08-16 2015-02-19 Rana Therapeutics, Inc. Oligonucleotides ciblant des regions de l'euchromatine de genes
JP2017509631A (ja) * 2014-03-13 2017-04-06 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト エストロゲン受容体突然変異体を調節する方法及び組成物
WO2017181026A1 (fr) * 2016-04-15 2017-10-19 Translate Bio Ma, Inc. Modulation sélective de l'expression de foxp3
WO2017184082A1 (fr) * 2016-04-22 2017-10-26 Nanyang Technological University Oligonucléotide chimère de perméation de lymphocytes, procédés et utilisations associés
WO2018031871A1 (fr) * 2016-08-12 2018-02-15 Translate Bio Ma, Inc. Modulation ex vivo de l'expression de foxp3
CN110290794A (zh) 2016-11-01 2019-09-27 纽约州州立大学研究基金会 5-卤代尿嘧啶修饰的微rna及其在癌症治疗中的用途
AU2017368050A1 (en) 2016-11-29 2019-06-20 Puretech Lyt, Inc. Exosomes for delivery of therapeutic agents
WO2019094404A1 (fr) * 2017-11-07 2019-05-16 Temple University-Of The Commonwealth System Of Higher Education Compositions et méthodes destinées à des lymphocytes t améliorés
US20210340536A1 (en) * 2018-09-26 2021-11-04 AUM LifeTech, Inc. 2' fana modified foxp3 antisense oligonucleotides and methods of use thereof
TW202028222A (zh) 2018-11-14 2020-08-01 美商Ionis製藥公司 Foxp3表現之調節劑
CN111378622B (zh) * 2018-12-29 2022-12-02 华东师范大学 核酸编码的car-t细胞及其制备方法和应用
WO2020212567A1 (fr) * 2019-04-18 2020-10-22 Proqr Therapeutics Ii B.V. Oligonucléotides antisens pour le traitement du syndrome d'usher
US11866708B2 (en) * 2019-10-22 2024-01-09 Board Of Regents, The University Of Texas System Tailored modulation of gene regulation programs via functional enhancer RNA
WO2022088342A1 (fr) * 2020-10-28 2022-05-05 苏州吉玛基因股份有限公司 Arnsi ciblant le gène foxp3 et son procédé de modification
US20230392760A1 (en) * 2022-06-02 2023-12-07 Black & Decker Inc. Portable illumination apparatus

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WO2008141282A2 (fr) * 2007-05-11 2008-11-20 The Regents Of The University Of Michigan Matériaux et procédés pour la suppression de tumeurs grâce à la foxp3
WO2013173652A1 (fr) * 2012-05-16 2013-11-21 Rana Therapeutics, Inc. Compositions et méthodes pour moduler l'expression génique

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EP1446500B1 (fr) * 2001-05-08 2008-08-20 Darwin Molecular Corporation Methode de regulation de la fonction immune chez les primates a l'aide de la proteine foxp3
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US20160122760A1 (en) 2016-05-05
EP3004354A1 (fr) 2016-04-13
WO2014197826A1 (fr) 2014-12-11
KR20160027968A (ko) 2016-03-10
JP2016521556A (ja) 2016-07-25
AU2014274730A1 (en) 2016-01-21

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