EP2986271A1 - Dentifrice contenant une argile smectite - Google Patents

Dentifrice contenant une argile smectite

Info

Publication number
EP2986271A1
EP2986271A1 EP14711984.6A EP14711984A EP2986271A1 EP 2986271 A1 EP2986271 A1 EP 2986271A1 EP 14711984 A EP14711984 A EP 14711984A EP 2986271 A1 EP2986271 A1 EP 2986271A1
Authority
EP
European Patent Office
Prior art keywords
preferred
composition
toothpaste composition
smectite clay
toothpaste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14711984.6A
Other languages
German (de)
English (en)
Inventor
Sembian CHANDRASEKARAN
Meenakshi IYER
Subhash Madhav PATIL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever PLC
Unilever NV
Original Assignee
Unilever PLC
Unilever NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever PLC, Unilever NV filed Critical Unilever PLC
Publication of EP2986271A1 publication Critical patent/EP2986271A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients

Definitions

  • a toothpaste composition having:
  • abrasives may also be used along with the calcium based abrasive, depending upon the intended degree of abrasion.
  • These include synthetic abrasive polishing agents such as amorphous precipitated silica and silica gels.
  • Other abrasive agents include magnesium carbonate, sodium metaphosphate, potassium metaphosphate, zirconium silicate, potassium metaphosphate, magnesium orthophosphate, tricalcium phosphate, magnesium orthophosphate, trimagnesium phosphate, aluminum silicate, zirconium silicate and perlite.
  • the disclosed composition contains upto 2 wt% thickening silica.
  • Conventional gels contain upto 8 wt% thickening silica whereas opaque products typically have 4 to 10 wt%.
  • Excessive thickening silica causes an adverse effect on release of flavor ingredients.
  • Preferred compositions have 1 .5 wt%, or even less than 1 wt% thickening silica.
  • Optimal compositions have less than 0.5 wt% thickening silica.
  • Toothpaste compositions typically contain about 20 wt% humectants, which is usually a combination of humectants. This necessitates the inclusion of from about 4 to 6 wt% thickening silica. Such toothpastes have excellent sensory profile, therefore highly preferred by consumers. On the other hand, products with humectants of about 6 to 10 wt% have less preferred sensory profile which may get further affected on reducing the silica content.
  • compositions have 3 to 15 wt%, more preferably 4 to 12 wt% and most preferably 6 to 12 wt% total humectant.
  • a particularly preferred humectant is sorbitol which is generally available in the form of 70% aqueous solution. Therefore, where sorbitol is used as a humectant, its actual dosage in the formulation is higher than the desired percentage to account for the water in the commercial product.
  • Suitable examples include quaternary ammonium compounds such as cetylpyridinium chloride; bis-biguanides such as chlorhexidine, chlorhexidine digluconate, hexetidine, octenidine, alexidine, TRICLOSAN ® and other halogenated bisphenolic compounds such as 2,2' methylenebis-(4-chloro-6-bromophenol).
  • a particularly preferred antibacterial agent is TRICLOSAN ® ; a broad-spectrum antimicrobial agent widely used in oral care products.
  • compositions which include an antibacterial agent, preferably triclosan we have observed significantly high uptake of the antibacterial agent by dental tissues including teeth. This is a hitherto unreported technical effect which is believed to be due to the presence of smectite clay.
  • CHEC carboxymethylhydroxyethyl cellulose
  • HPHEC hydroxypropylhydroxyethyl cellulose
  • MC methyl cellulose
  • MHPC methylhydroxypropyl cellulose
  • MHEC methylhydroxyethyl cellulose
  • carboxymethylmethyl cellulose CMMC
  • HMCMC hydrophobically modified carboxymethyl cellulose
  • HMHPC hydrophobically modified hydroxypropyl cellulose
  • HMEHEC hydrophobically modified ethylhydroxyethyl cellulose
  • HMHPHEC hydrophobically modified hydroxypropylhydroxyethyl cellulose
  • a highly preferred binder is Sodium carboxymethyl cellulose (SCMC).
  • SCMC Sodium carboxymethyl cellulose
  • Particularly preferred sodium carboxymethyl celluloses include those with degree of substitution of from 0.6 to 0.99, preferably from 0.7 to 0.95.
  • preferred SCMCs include those with viscosity of 250 mPa.s to 10000 mPa.s as measured on a Brookfield viscometer TA spindle at 30 rpm, 23 °C and reading after 30 seconds when slurried with flavour in a 1 :1 ratio.
  • compositions which have cellulosic binder in addition to the smectite clay the ratio of the amount of smectite clay to the cellulosic binder is in the range of 1 :0.2 to 1 :0.9.
  • Excessive cellulosic binder leads to compositions which may show tailing effect while dispensing the composition on a toothbrush.
  • most of the cellulosic binders and some others like carrageenan are expensive ingredients.
  • compositions may also include one or more other ingredients as described hereinafter.
  • Other thickening agents may also include one or more other ingredients as described hereinafter.
  • Preferred toothpaste compositions can include alkali metal silicate.
  • the alkali metal is sodium or potassium, preferably sodium.
  • Sodium silicate is generally available as 10 to 40 % aqueous solution, most common being 30 % solution.
  • Sodium silicate is available as neutral sodium silicate or alkaline sodium silicate.
  • Preferred toothpastes have neutral sodium silicate.
  • Sodium silicate is available with varying ratios of Na 2 0: Si0 2 .
  • Anionic surfactants useful herein include the water-soluble salts of alkyl sulfates having from 8 to 20 carbon atoms in the alkyl radical (e.g., sodium alkyl sulfate) and the water- soluble salts of sulfonated monoglycerides of fatty acids having from 8 to 20 carbon atoms.
  • Sodium lauryl sulfate and sodium coconut monoglyceride sulfonates are examples of anionic surfactants of this type.
  • Titanium dioxide can also be added to the composition for opacity. Titanium dioxide is generally included from 0.25 to 5 wt%. It is preferred that the toothpaste compositions contain a flavour. Suitable flavoring components include oil of wintergreen, oil of peppermint, oil of spearmint, clove bud oil, menthol, anethole, methyl salicylate, eucalyptol, cassia, 1-menthyl acetate, sage, eugenol, parsley oil, oxanone, alpha-irisone, marjoram, lemon, orange, propenyl guaethol, cinnamon, vanillin, ethyl vanillin, heliotropine, 4-cis-heptenal, diacetyl, methyl- para-tert-butyl phenyl acetate, and mixtures thereof.
  • Suitable flavoring components include oil of wintergreen, oil of peppermint, oil of spearmint, clove bud oil, menthol, anethole
  • a preferred toothpaste composition having the formulation as in table 5 was prepared.
  • the preferred composition reduces growth of mutans Streptococci by a significantly better margin as compared to other toothpastes.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

Cette invention concerne une composition de dentifrice comprenant : (i) de 20 à 60 % en poids d'un abrasif à base de calcium ; (ii) de 3 à 15 % en poids d'un humidifiant ; et (iii) jusqu'à 2 % en poids d'une silice épaississante ; la composition comprenant de 0,2 à 3 % en poids d'argile smectite. La composition décrite offre un profil sensoriel supérieur ainsi qu'une fixation accrue de l'agent antibactérien par le tissu buccal.
EP14711984.6A 2013-04-15 2014-03-25 Dentifrice contenant une argile smectite Withdrawn EP2986271A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1399MU2013 2013-04-15
EP13169725 2013-05-29
PCT/EP2014/055891 WO2014170096A1 (fr) 2013-04-15 2014-03-25 Dentifrice contenant une argile smectite

Publications (1)

Publication Number Publication Date
EP2986271A1 true EP2986271A1 (fr) 2016-02-24

Family

ID=50346022

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14711984.6A Withdrawn EP2986271A1 (fr) 2013-04-15 2014-03-25 Dentifrice contenant une argile smectite

Country Status (3)

Country Link
EP (1) EP2986271A1 (fr)
CN (1) CN105142597A (fr)
WO (1) WO2014170096A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287244A (zh) * 2015-11-24 2016-02-03 山东司邦得制药有限公司 蒙脱石功能性牙膏及其制备方法
EP3880157A1 (fr) * 2018-12-20 2021-09-22 Colgate-Palmolive Company Compositions de soins buccodentaires
CN115175659A (zh) 2020-02-18 2022-10-11 联合利华知识产权控股有限公司 无润湿剂的牙膏组合物
WO2022072605A1 (fr) 2020-09-30 2022-04-07 Lubrizol Advanced Materials, Inc. Compositions de soins bucco-dentaires à stabilité améliorée

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5257339A (en) * 1975-11-07 1977-05-11 Kao Corp Tooth paste composition
US5188821A (en) 1987-01-30 1993-02-23 Colgate-Palmolive Company Antibacterial antiplaque oral composition mouthwash or liquid dentifrice
US6451291B1 (en) 2000-10-11 2002-09-17 Colgate Palmolive Company Surfactant system for increasing dental tissue antibacterial agent uptake
CN1298310C (zh) * 2001-10-02 2007-02-07 荷兰联合利华有限公司 含有精细研磨的天然白垩的口腔组合物
EP2268258A1 (fr) 2008-04-28 2011-01-05 The Procter & Gamble Company Compositions pour soins buccaux
US9308158B2 (en) * 2011-07-12 2016-04-12 Conopco, Inc. Toothpaste comprising calcium based abrasives
CN102579275B (zh) * 2012-02-22 2013-06-12 合肥学院 一种含铝镁硅酸盐的美容牙膏及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2014170096A1 *

Also Published As

Publication number Publication date
WO2014170096A1 (fr) 2014-10-23
CN105142597A (zh) 2015-12-09

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