EP2986271A1 - Zahnpasta mit smektitton - Google Patents
Zahnpasta mit smektittonInfo
- Publication number
- EP2986271A1 EP2986271A1 EP14711984.6A EP14711984A EP2986271A1 EP 2986271 A1 EP2986271 A1 EP 2986271A1 EP 14711984 A EP14711984 A EP 14711984A EP 2986271 A1 EP2986271 A1 EP 2986271A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- preferred
- composition
- toothpaste composition
- smectite clay
- toothpaste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Definitions
- a toothpaste composition having:
- abrasives may also be used along with the calcium based abrasive, depending upon the intended degree of abrasion.
- These include synthetic abrasive polishing agents such as amorphous precipitated silica and silica gels.
- Other abrasive agents include magnesium carbonate, sodium metaphosphate, potassium metaphosphate, zirconium silicate, potassium metaphosphate, magnesium orthophosphate, tricalcium phosphate, magnesium orthophosphate, trimagnesium phosphate, aluminum silicate, zirconium silicate and perlite.
- the disclosed composition contains upto 2 wt% thickening silica.
- Conventional gels contain upto 8 wt% thickening silica whereas opaque products typically have 4 to 10 wt%.
- Excessive thickening silica causes an adverse effect on release of flavor ingredients.
- Preferred compositions have 1 .5 wt%, or even less than 1 wt% thickening silica.
- Optimal compositions have less than 0.5 wt% thickening silica.
- Toothpaste compositions typically contain about 20 wt% humectants, which is usually a combination of humectants. This necessitates the inclusion of from about 4 to 6 wt% thickening silica. Such toothpastes have excellent sensory profile, therefore highly preferred by consumers. On the other hand, products with humectants of about 6 to 10 wt% have less preferred sensory profile which may get further affected on reducing the silica content.
- compositions have 3 to 15 wt%, more preferably 4 to 12 wt% and most preferably 6 to 12 wt% total humectant.
- a particularly preferred humectant is sorbitol which is generally available in the form of 70% aqueous solution. Therefore, where sorbitol is used as a humectant, its actual dosage in the formulation is higher than the desired percentage to account for the water in the commercial product.
- Suitable examples include quaternary ammonium compounds such as cetylpyridinium chloride; bis-biguanides such as chlorhexidine, chlorhexidine digluconate, hexetidine, octenidine, alexidine, TRICLOSAN ® and other halogenated bisphenolic compounds such as 2,2' methylenebis-(4-chloro-6-bromophenol).
- a particularly preferred antibacterial agent is TRICLOSAN ® ; a broad-spectrum antimicrobial agent widely used in oral care products.
- compositions which include an antibacterial agent, preferably triclosan we have observed significantly high uptake of the antibacterial agent by dental tissues including teeth. This is a hitherto unreported technical effect which is believed to be due to the presence of smectite clay.
- CHEC carboxymethylhydroxyethyl cellulose
- HPHEC hydroxypropylhydroxyethyl cellulose
- MC methyl cellulose
- MHPC methylhydroxypropyl cellulose
- MHEC methylhydroxyethyl cellulose
- carboxymethylmethyl cellulose CMMC
- HMCMC hydrophobically modified carboxymethyl cellulose
- HMHPC hydrophobically modified hydroxypropyl cellulose
- HMEHEC hydrophobically modified ethylhydroxyethyl cellulose
- HMHPHEC hydrophobically modified hydroxypropylhydroxyethyl cellulose
- a highly preferred binder is Sodium carboxymethyl cellulose (SCMC).
- SCMC Sodium carboxymethyl cellulose
- Particularly preferred sodium carboxymethyl celluloses include those with degree of substitution of from 0.6 to 0.99, preferably from 0.7 to 0.95.
- preferred SCMCs include those with viscosity of 250 mPa.s to 10000 mPa.s as measured on a Brookfield viscometer TA spindle at 30 rpm, 23 °C and reading after 30 seconds when slurried with flavour in a 1 :1 ratio.
- compositions which have cellulosic binder in addition to the smectite clay the ratio of the amount of smectite clay to the cellulosic binder is in the range of 1 :0.2 to 1 :0.9.
- Excessive cellulosic binder leads to compositions which may show tailing effect while dispensing the composition on a toothbrush.
- most of the cellulosic binders and some others like carrageenan are expensive ingredients.
- compositions may also include one or more other ingredients as described hereinafter.
- Other thickening agents may also include one or more other ingredients as described hereinafter.
- Preferred toothpaste compositions can include alkali metal silicate.
- the alkali metal is sodium or potassium, preferably sodium.
- Sodium silicate is generally available as 10 to 40 % aqueous solution, most common being 30 % solution.
- Sodium silicate is available as neutral sodium silicate or alkaline sodium silicate.
- Preferred toothpastes have neutral sodium silicate.
- Sodium silicate is available with varying ratios of Na 2 0: Si0 2 .
- Anionic surfactants useful herein include the water-soluble salts of alkyl sulfates having from 8 to 20 carbon atoms in the alkyl radical (e.g., sodium alkyl sulfate) and the water- soluble salts of sulfonated monoglycerides of fatty acids having from 8 to 20 carbon atoms.
- Sodium lauryl sulfate and sodium coconut monoglyceride sulfonates are examples of anionic surfactants of this type.
- Titanium dioxide can also be added to the composition for opacity. Titanium dioxide is generally included from 0.25 to 5 wt%. It is preferred that the toothpaste compositions contain a flavour. Suitable flavoring components include oil of wintergreen, oil of peppermint, oil of spearmint, clove bud oil, menthol, anethole, methyl salicylate, eucalyptol, cassia, 1-menthyl acetate, sage, eugenol, parsley oil, oxanone, alpha-irisone, marjoram, lemon, orange, propenyl guaethol, cinnamon, vanillin, ethyl vanillin, heliotropine, 4-cis-heptenal, diacetyl, methyl- para-tert-butyl phenyl acetate, and mixtures thereof.
- Suitable flavoring components include oil of wintergreen, oil of peppermint, oil of spearmint, clove bud oil, menthol, anethole
- a preferred toothpaste composition having the formulation as in table 5 was prepared.
- the preferred composition reduces growth of mutans Streptococci by a significantly better margin as compared to other toothpastes.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1399MU2013 | 2013-04-15 | ||
EP13169725 | 2013-05-29 | ||
PCT/EP2014/055891 WO2014170096A1 (en) | 2013-04-15 | 2014-03-25 | Toothpaste containing smectite clay |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2986271A1 true EP2986271A1 (de) | 2016-02-24 |
Family
ID=50346022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14711984.6A Withdrawn EP2986271A1 (de) | 2013-04-15 | 2014-03-25 | Zahnpasta mit smektitton |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2986271A1 (de) |
CN (1) | CN105142597A (de) |
WO (1) | WO2014170096A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105287244A (zh) * | 2015-11-24 | 2016-02-03 | 山东司邦得制药有限公司 | 蒙脱石功能性牙膏及其制备方法 |
EP3880157A1 (de) * | 2018-12-20 | 2021-09-22 | Colgate-Palmolive Company | Mundpflegezusammensetzungen |
EP4106715B1 (de) * | 2020-02-18 | 2023-10-18 | Unilever IP Holdings B.V. | Befeuchtungsmittelfreie zahnpastazusammensetzung |
WO2022072605A1 (en) | 2020-09-30 | 2022-04-07 | Lubrizol Advanced Materials, Inc. | Oral care compositions with improved stability |
CN114306129B (zh) * | 2022-01-10 | 2024-06-07 | 山东中大药业有限公司 | 一种用于口腔清洁的泡腾片及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5257339A (en) * | 1975-11-07 | 1977-05-11 | Kao Corp | Tooth paste composition |
US5188821A (en) | 1987-01-30 | 1993-02-23 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
US6451291B1 (en) | 2000-10-11 | 2002-09-17 | Colgate Palmolive Company | Surfactant system for increasing dental tissue antibacterial agent uptake |
BR0213608A (pt) * | 2001-10-02 | 2004-09-14 | Unilever Nv | Composição oral |
EP2268258A1 (de) | 2008-04-28 | 2011-01-05 | The Procter & Gamble Company | Mundpflegezusammensetzungen |
CN103702652A (zh) * | 2011-07-12 | 2014-04-02 | 荷兰联合利华有限公司 | 含有钙基磨料的牙膏 |
CN102579275B (zh) * | 2012-02-22 | 2013-06-12 | 合肥学院 | 一种含铝镁硅酸盐的美容牙膏及其制备方法 |
-
2014
- 2014-03-25 CN CN201480021383.9A patent/CN105142597A/zh active Pending
- 2014-03-25 WO PCT/EP2014/055891 patent/WO2014170096A1/en active Application Filing
- 2014-03-25 EP EP14711984.6A patent/EP2986271A1/de not_active Withdrawn
Non-Patent Citations (2)
Title |
---|
None * |
See also references of WO2014170096A1 * |
Also Published As
Publication number | Publication date |
---|---|
CN105142597A (zh) | 2015-12-09 |
WO2014170096A1 (en) | 2014-10-23 |
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Legal Events
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DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20170306 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20170718 |