EP2957337B1 - Système de mélange sous vide et procédé de mélange de ciment osseux en polyméthacrylate de méthyle - Google Patents

Système de mélange sous vide et procédé de mélange de ciment osseux en polyméthacrylate de méthyle Download PDF

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Publication number
EP2957337B1
EP2957337B1 EP15170080.4A EP15170080A EP2957337B1 EP 2957337 B1 EP2957337 B1 EP 2957337B1 EP 15170080 A EP15170080 A EP 15170080A EP 2957337 B1 EP2957337 B1 EP 2957337B1
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EP
European Patent Office
Prior art keywords
cartridge
pump
plunger
mixing system
internal space
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP15170080.4A
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German (de)
English (en)
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EP2957337A1 (fr
Inventor
Sebastian Vogt
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Heraeus Medical GmbH
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Heraeus Medical GmbH
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Publication of EP2957337A1 publication Critical patent/EP2957337A1/fr
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
    • B01F33/71—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming working at super-atmospheric pressure, e.g. in pressurised vessels
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B33/00—Pumps actuated by muscle power, e.g. for inflating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B01F23/51—Methods thereof
    • B01F23/511—Methods thereof characterised by the composition of the liquids or solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B01F23/59—Mixing systems, i.e. flow charts or diagrams
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5014—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use movable by human force, e.g. kitchen or table devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/712—Feed mechanisms for feeding fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7131—Breaking or perforating packages, containers or vials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/718—Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • B01F35/754251—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers reciprocating in the mixing receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/20—Mixing of ingredients for bone cement

Definitions

  • the invention relates to a vacuum mixing system for mixing polymethyl methacrylate bone cement (PMMA bone cement) from two starting components, in particular for mixing a medical bone cement, and for storing the starting components.
  • PMMA bone cement polymethyl methacrylate bone cement
  • the invention further relates to a method for mixing polymethyl methacrylate bone cement.
  • the invention thus provides a vacuum mixing system for the storage, mixing and optionally also the discharge of polymethyl methacrylate bone cement. Furthermore, the invention relates to a method for transfer of monomer liquid into the vacuum mixing system and a method for mixing the components of polymethylmethacrylate bone cement.
  • PMMA bone cements are based on the fundamental work of Sir Charnley.
  • PMMA bone cements consist of a liquid monomer component and a powder component.
  • the monomer component generally contains the monomer methyl methacrylate and an activator (N, N-dimethyl-p-toluidine) dissolved therein.
  • the powder component also referred to as bone cement powder, has one or more polymers, an X-ray opaque and the initiator dibenzoyl peroxide.
  • the polymers of the powder component are prepared based on methyl methacrylate and comonomers such as styrene, methyl acrylate or similar monomers by polymerization, preferably suspension polymerization.
  • the activator reacts N, N-dimethyl-p-toluidine with dibenzoyl peroxide to form radicals.
  • the radicals formed initiate the radical polymerization of the methyl methacrylate.
  • the viscosity of the cement dough increases until it solidifies.
  • the monomer most commonly used in polymethyl methacrylate bone cements is methyl methacrylate.
  • Redox initiator systems usually consist of peroxides, accelerators and optionally suitable reducing agents.
  • a radical formation takes place only when all components of the redox initiator systems interact. Therefore, the components of the redox initiator system are placed in the separate starting components so that they can not initiate radical polymerization.
  • the starting components are storage stable with a suitable composition. It is only when the two starting components are mixed to form a cement dough that the components of the redox initiator system previously stored separately in the two pastes, liquids or powders react, forming radicals which trigger the radical polymerization of the at least one monomer. The radical polymerization then leads to the formation of polymers with consumption of the monomer, wherein the cement paste hardens.
  • PMMA bone cements can be mixed in suitable mixing beakers by means of spatulas by mixing the cement powder with the monomer liquid.
  • a disadvantage of this approach that air pockets may be present in the formed cement dough, which may later cause a destabilization of the bone cement.
  • the mixing of bone cement powder with the monomer liquid in vacuum mixing systems is preferred because air entrainment from the cement dough is largely removed by mixing in a vacuum and thus optimum cement quality is achieved.
  • Vacuum mixed bone cements have significantly reduced porosity and therefore exhibit improved mechanical properties.
  • a variety of vacuum cementing systems have been disclosed, of which the following are by way of example: US 6,033,105 A . US 5,624,184 A . US 4,671,263 A . US 4,973,168 A .
  • a further development in the cementing technique is cementing systems in which both the cement powder and the monomer liquid are already in separate compartments of the mixing systems are packaged and which are mixed together just before the cement application in the cementing system.
  • Such full-prepacked mixing systems have been combined with the EP 0 692 229 A1 , of the DE 10 2009 031 178 B3 , of the US 5,997,544 A , of the US Pat. No. 6,709,149 B1 , of the DE 698 12 726 T2 and the US 5,588,745 A proposed. Even with these mixing systems, an external vacuum source is necessary.
  • the patent DE 10 2009 031 178 B3 discloses a generic vacuum mixing device with a two-part discharge piston, which can also be used for a vacuum mixing device according to the invention.
  • the US 6,536,937 B1 which discloses a vacuum mixing system according to the preamble of claim 1 and a method according to the preamble of claim 16, a vacuum mixing system in which a pump is powered by a motor with energy from an electrical energy storage.
  • a vacuum mixing system in which a pump is powered by a motor with energy from an electrical energy storage.
  • an apparatus and method for generating vacuum for vacuum cementing systems is known in which the flow from a pressurized gas cartridge is used to generate a vacuum.
  • the US 5,571,282 A discloses a motorized mixer for bone cements.
  • vacuum mixing systems When using vacuum mixing systems for cementing, external vacuum pumps must be provided. These vacuum pumps are expensive and must be cleaned after use. Furthermore, vacuum hoses are necessary for connecting the vacuum pumps with the vacuum mixing systems. These vacuum hoses must be enclosed with the vacuum mixing systems. Therefore, before mixing with a vacuum mixing system, the vacuum pump must first be set up in the operating room (operating room) and connected to an energy source such as compressed air or electricity. Thereafter, the vacuum pump is connected to the vacuum mixing system with a vacuum hose. These assembly steps cost valuable operating time and are potentially flawed. The vacuum pump and the connection lines to the vacuum mixing system and to external power sources and supply lines require space and represent potential tripping hazards and obstacles that can interfere with the occasionally hectic flow during an operation.
  • the object of the invention is therefore to overcome the disadvantages of the prior art.
  • the disadvantages of the known vacuum mixing systems with external vacuum source are to be overcome.
  • the invention has the particular task of developing a vacuum mixing system in which a negative pressure is generated only immediately before the mixing of the cement components.
  • the device should be maximally simplified and allow at least one time to generate a negative pressure in a cement cartridge with respect to the surrounding atmosphere.
  • the vacuum mixing system is capable of allowing a transfer of monomer liquid from a monomer container into a cartridge filled with cement powder.
  • a method is then also to be provided which allows for monomer transfer and vacuum mixing in full-prepacked mixing systems.
  • the vacuum mixing system to be developed, mainly from inexpensive plastic can be manufactured.
  • a cost-effective and reliably functioning device for mixing a medical cement and optionally for storage of the starting components and a method for mixing the bone cement is to be found, in which the simplest possible manual operation for mixing the starting components can be used, if possible without an external or additional energy source must be used and without air pockets in the mix can arise.
  • the main component of the polymethyl methacrylate bone cement as a mix should be a powder and the second component should be in the form of a liquid.
  • the two starting components of the bone cement are preferred can be stored separately in the vacuum mixing system and can be safely combined by using the device.
  • a vacuum mixing system for mixing polymethyl methacrylate bone cement comprising at least one cartridge with an evacuable interior for mixing the bone cement, a pump for generating a negative pressure and a connecting line, which generates the interior of the at least one cartridge with the pump a vacuum
  • the vacuum mixing system comprises a cocked return element for driving the pump, which is connected to the pump or connectable and stored in the energy for at least one pumping operation of the pump, wherein in the pumping operation by a consumption of energy from the cocked return element With the pump, a negative pressure can be generated, so that with the negative pressure through the connecting line gas from the interior of the at least one cartridge is evacuated.
  • negative pressure in the present case always refers to a relative to the surrounding atmosphere related pressure, which is smaller than the surrounding atmospheric pressure.
  • the pump is integrated in the vacuum mixing system.
  • the polymethyl methacrylate bone cement is preferably mixed from at least two components or can be produced from at least two components. Particularly preferably, one component is liquid and another component is powdery.
  • the pressure in the interior of the at least one cartridge can be reduced by at least 50% by the pumping process, preferably by at least 90%.
  • the starting components for the mix, in particular for the PMMA bone cement, according to the invention already contained in the cartridges.
  • the device according to the invention is preferably also suitable for storing the starting components, in particular when the containers are inserted into the device or the containers are a fixed part of the device.
  • the mixture is particularly preferably a bone cement, in particular a PMMA bone cement.
  • gas from the interior of the at least one cartridge is evacuated and gas from a line between the interior and a liquid container can be evacuated and the negative pressure with a first component of the PMMA bone cement in the cartridge is to draw mixing liquid from the liquid container into the interior of the cartridge.
  • the pump has a gas-tight pumping space and in the pump a movable piston or a movable wall is provided as a boundary of the pumping space, the piston or the wall with the energy of the tensioned return element in one direction, preferred unidirectional, can be driven, so that is increased by the movement of the piston or the wall of the pump chamber and with the resulting negative pressure in the pump chamber, the interior of the at least one cartridge can be evacuated through the connecting line.
  • the pump has a rotating wheel, a periodically operating piston or a periodically operating diaphragm.
  • the embodiment with a movable piston or a movable wall is preferred according to the invention, since the structure is much simpler, Seaunanrizer (rotating parts could block) and thus cheaper, but at the same time for the short-term generation of a negative pressure in the interior of the cartridge is already sufficient. Due to the special requirements, such as the low volume of the interior of the cartridge, more complex pump systems are not necessary.
  • the increase in volume of the pump chamber is at least as large as the free volume of the interior of the cartridge, preferably the increase in volume of the pump chamber is at least as large as the sum of the volume of the interior of the cartridge in which a first powdered Component of the PMMA bone cement is contained, and the volume of the connecting line and the volume of a conduit between the interior and a liquid container and the volume of one with the first Component of the PMMA bone cement in the cartridge to be mixed liquid in the liquid container, wherein the liquid is a second component of the PMMA bone cement.
  • the volume of the pump space before the pumping process is ideally as small as possible. It may therefore be preferred that the volume of the pump chamber after pumping is at least 5 times greater than the volume of the pump chamber before the pumping process, more preferably at least 10 times greater than the volume of the pump chamber before the pumping process.
  • the vacuum mixing system comprises a mixing device for mixing the contents of the at least one cartridge, wherein preferably the mixing device is arranged in the interior of the cartridge and / or manually or by a motor can be driven.
  • the cartridge has a pressure-tight passage through which a rod or a mixing tube is carried out, with which the mixing device is to be operated from outside the cartridge.
  • the rod or the mixing tube is preferably rotatable and slidably mounted in the implementation in the longitudinal direction. With the mixing device, the contents of the cartridge can be mixed well.
  • the vacuum mixing system has less than 30 kg total weight, more preferably less than 10 kg total weight.
  • the low weight has the advantage that the mixing device can be taken and can be used without connection to supply lines and without much preparation.
  • a particularly easy-to-use vacuum mixing system can be produced in that the vacuum mixing system has a manually operable control element by the operation of the energy from the cocked return element is releasable, which is to be driven by the energy released, the pump and the driven pump evacuated the interior of the cartridge. This simplifies the operation of the vacuum mixing system. Despite the compact design so easy operation can be ensured.
  • the tensioned return element is a tensioned spring, particularly preferably a tensioned steel spring.
  • Tensioned reset elements hold the energy for longer periods.
  • the small amount of stored energy is sufficient to ensure a sufficient negative pressure for evacuating the interior of the cartridge.
  • a movable discharge piston for discharging the mixed bone cement is arranged from the cartridge, wherein the discharge piston is preferably releasably locked or locked to prevent movement of the discharge piston under the action of negative pressure.
  • the discharge piston simplifies the operation of the vacuum mixing system.
  • the pump is driven by the tensioned restoring element, in particular by a tensioned spring element, wherein preferably an expansion or contraction of the restoring element, in particular of the spring element generates a negative pressure in the interior of the cartridge relative to the surrounding atmosphere.
  • This structure is particularly simple and inexpensive to implement. At the same time, however, a reliably operating vacuum mixing system can be constructed with this structure, which is relatively insusceptible to malfunction.
  • the cartridge is a cement powder filled cement cartridge and the vacuum mixing system has a container separate from the cement cartridge, in which a monomer liquid is contained, wherein the container is liquid impermeable connected by an openable partition member with the interior of the cement cartridge and the interior of the cement cartridge is connected to the pump or permeable to gas.
  • This structure is particularly simple and the parts for this can be made of plastic by injection molding.
  • the spring element in the storage state, the spring element is compressed and is held by the piston of the pump by the locked connection element in the compressed state.
  • the piston is displaced so that the volume of the pump chamber formed by the hollow cylinder, the closure and the piston is at least equal to the volume of the interior of the cartridge to be evacuated.
  • a limiting element is arranged, that limits the movement of the piston such that it can not escape from the hollow cylinder.
  • the piston on the side facing away from the closure contains an optical marker which is visually recognizable on the outside of the vacuum mixing system when the maximum movement of the piston has occurred and thereby indicates the position of the piston after its maximum movement.
  • the objects on which the present invention is based are also achieved by a method for mixing polymethyl methacrylate bone cement in an interior of a cartridge of a vacuum mixing system, in particular a vacuum mixing system according to the invention, in which an energy stored in an energy storage unit integrated in the vacuum mixing system is used to drive a pump of the vacuum mixing system is evacuated, with the thus driven pump, the interior of the cartridge and in the interior of the cartridge, a bone cement is mixed, wherein the volume of a pump chamber of the pump is increased by relaxing a return element as an integrated energy storage and by the resulting negative pressure of the interior of the Cartridge is evacuated.
  • a cement powder is contained in the interior of the cartridge and a gas is evacuated from the interior of the cartridge with the pump, a monomer liquid is introduced into the interior of the cartridge and the monomer liquid with the cement powder in the evacuated Interior is mixed.
  • a connecting element is released from a piston of the pump, then a compressed return element moves the piston axially in a hollow cylinder of the pump, whereby a negative pressure relative to the surrounding atmosphere is generated, thereby through a connecting line of gas from the interior of the cartridge is sucked into the hollow cylinder, then manually or motor driven with a mixing device, a cement powder is mixed with a monomer liquid, then the cartridge is removed with the mixed cement dough and the cement paste is pressed out of the cartridge by axial movement of a Austragskolbens.
  • the cement powder is arranged in the cartridge, the monomer liquid is arranged in a separate container from the cartridge, wherein the monomer liquid is separated via a separating element of the cement powder in the cartridge, the separating element is opened before the connecting element of the piston is released, so that a liquid-permeable connection between the interior of the cartridge and the container is formed, then the compressed spring element moves the piston axially in the hollow cylinder, whereby a negative pressure is generated with respect to the surrounding atmosphere, thereby through the connecting line gas from the interior the cartridge is sucked into the hollow cylinder and is sucked by the negative pressure formed in the interior of the cartridge monomer liquid into the cartridge.
  • the invention is based on the surprising finding that, with the aid of a pump and an integrated energy store in the form of a tensioned return element, in which a sufficient amount of energy is stored to evacuate the interior of the cartridge with the pump, one of external energy sources succeeds and provide other supply lines independent vacuum mixing system.
  • the vacuum mixing system according to the invention can be constructed compact, lightweight and space-saving.
  • the pump can be constructed with the simplest means, so that the entire vacuum mixing system can be used as a single-use system.
  • the energy can also be used according to the invention and preferably also for converting a monomer liquid into the cement powder with the pump.
  • the two components of the PMMA bone cement can then be mixed in a vacuum or in the negative pressure.
  • the vacuum mixing system according to the invention also has the advantage that the gases evacuated from the cartridge are not released to the environment, since these gases then do not have to be filtered in order to remove unwanted constituents (such as, for example, methyl methacrylate vapors). Instead, the gases simply remain in the pump or pump space.
  • a device for generating a vacuum or for generating a negative pressure is included, which for the temporary generation of a negative pressure before and during the Mixing a powdery component with a liquid monomer component of the polymethyl methacrylate bone cement is suitable.
  • the idea underlying the invention is based on the recognition that only a relatively small amount of energy is necessary to generate the vacuum or negative pressure in a cartridge, which is necessary to mix the starting components of a bone cement under the vacuum or the vacuum.
  • the amount of energy to transfer the monomer liquid into the cement powder is also low.
  • This small amount of energy can be stored in an internal energy store of the vacuum mixing system with which the pump is driven.
  • Already the amount of energy that is stored in a tensioned steel spring or another restoring element is sufficient according to the invention to provide the energy for driving a vacuum mixing system according to the invention.
  • FIGS. 1 to 3 show a schematic cross-sectional view of a vacuum mixing system according to the invention prior to the pumping operation.
  • the vacuum mixing system consists essentially of three parts, a cartridge system 1, a liquid container 2 and a foot part 3.
  • the cartridge system 1 is connected to the liquid container 2 via the foot part 3.
  • the foot part 3 forms, inter alia, the base of the compact vacuum mixing system.
  • the cartridge system 1 has a cylindrical cartridge 4 with a circular base, which is fixed vertically to the foot part 3. For this purpose, an opening with an internal thread is provided at the front of the cartridge 4, which is screwed onto a socket on the foot part 3 with an external thread.
  • a cement powder (not shown) is contained inside the cartridge 4.
  • a mixing device 6 with two or more mixing blades 6, which are fastened to a mixing tube 8, is arranged inside the cartridge 4.
  • the mixing tube 8 is rotatable and guided in the longitudinal direction displaceable by a sterilization piston 9.
  • the implementation is pressure-tight and gas-tight.
  • the sterilization flask 9 has a membrane (not shown) that is permeable to a sterilizing gas but is not permeable to the cement powder.
  • the sterilization piston 9 is inserted after the filling of the cement powder in the cartridge 4 and closes the interior of the cartridge 4 to the outside. Subsequently, the contents of the cartridge 4 can be sterilized through the permeable membrane with ethylene
  • a sealing piston 10 can be pressed into the sterilization piston 9 and connected to this gas and pressure-tight.
  • the mutually attached pistons 9, 10 then together form a discharge piston 9, 10, with which the contents of the cartridge 4 can be pressed out through the bottom-side opening.
  • the sterilization piston 9 but on the opposite side (in FIGS. 1 to 3 locked above), wherein the lock is releasable.
  • a handle 11 is attached outside the cartridge 4, with which the mixing blades 6 in the interior of the cartridge 4, ie in the interior of the cartridge 4 are manually rotatable and displaceable in the longitudinal direction of the cartridge 4.
  • a passage is provided, which is connected to a connecting line 12 in the form of a flexible vacuum line 12.
  • the sealing piston 10 is otherwise tight.
  • the front of the cartridge 4 (in the FIGS. 1 to 3 below) is connected by the foot part 3 via a fluid line 14 pressure-tight manner with the liquid container 2.
  • a siphon 16 is provided, with which it is prevented that a monomer (not shown) contained in the liquid container 2 can unintentionally penetrate into the cartridge 4.
  • the vacuum line 12 is also guided in the foot part 3 and guided there in the foot part 3 to a pump 18, so that the Implementation in the sealing piston 10 via the vacuum line 12 pressure-tight with the pump 18 is more precisely connected to the interior of the pump 18.
  • the pump 18 has a stable hollow cylinder 20 which is pressure-tightly separated into two parts via a piston 22.
  • the mouth 24 and the terminal 24 is provided for the vacuum line 12.
  • This part of the interior of the hollow cylinder 20 forms a pump chamber 26.
  • a negative pressure in the pump chamber 26 can thus act through the vacuum line 12 into the interior of the cartridge 4, or a gas from the interior of the cartridge 4 are evacuated when the sealing piston 10, as in the Figures 2 and 3 shown connected to the sterilization piston 9.
  • the vacuum mixing system is characterized by a tensioned steel spring 28, which is arranged in the pumping space 26 about a screw 30 and about a cylindrical extension on the piston 22 around.
  • the screw 30 is gas and pressure tight and rotatably guided through a passage in the pump chamber 26.
  • the screw 30 forms for a closure of the pump chamber 26 and the interior of the hollow cylinder 20.
  • the screw 30 is screwed with an external thread 32 in an internal thread 33 in the cylindrical extension of the piston 22 and thus holds the piston 22 in position.
  • the steel spring 28 is between the piston 22 and the side (the base) of the hollow cylinder 20 with the passage for the screw 30 (this page is in the FIGS.
  • the steel spring 28 is thus used as a compression spring 28.
  • an amount of energy is stored sufficient to evacuate with the pump 18, the interior of the cartridge 4, the vacuum line 12 and the liquid line 14 and the monomer liquid from the liquid container 2 through the liquid line 14 into the interior of the cartridge 4 to draw.
  • an extension 34 is arranged in the form of a pin 34, which emerge from the hollow cylinder 20 through an opening 36 in the base of the hollow cylinder 20, which faces the base with the passage for the screw 30 can.
  • a glass ampoule 40 is arranged with a breakable head 42.
  • the glass ampoule 40 contains the monomer liquid.
  • the head 42 of the glass ampule 40 can be broken off or sheared off by turning a rotary lever 44.
  • the rotary lever 44 thus opens the connection and thus establishes a connection between the monomer liquid and the liquid line 14.
  • a valve element (not shown) may be provided, which can be opened with the rotary lever 44.
  • the liquid container 2 is closed gas-tight and pressure-tight with a lid 46 after the glass ampoule 40 has been inserted into the liquid container 2.
  • the monomer liquid After breaking the glass ampule 40, the monomer liquid is available in the liquid container 2 and can be passed through the liquid line 14 into the interior of the ampoule 4, in which a negative pressure in the interior of the ampoule 4 is used to remove the monomer liquid from the liquid container 2 to suck the interior of the ampoule 4.
  • the monomer liquid can then be mixed with the cement powder with the mixing device 6 under vacuum or under reduced pressure to produce the bone cement or a bone cement paste.
  • the vacuum mixing system is characterized by the following method.
  • the pump 18 is triggered by the screw 30 is screwed out with the external thread 28 from the internal thread 33 of the piston 22. This is done when the cartridge 4 is ready for use by inserting the seal piston 10, as in FIG FIG. 2 shown.
  • the energy of the compressed steel spring 28 is released and the piston 22 is accelerated in the direction of the opening 36.
  • the pump chamber 26 is increased.
  • the pressure in the pump chamber 26 is reduced. Gas flows from the vacuum line 12, the interior of the cartridge 4 and the liquid line 14 into the pump chamber.
  • the interior of the cartridge 4 is evacuated.
  • the piston 22 is up to the end of the hollow cylinder 20 (in the FIGS. 1 to 3 right) accelerates until the pin 34 protrudes from the opening 36.
  • This arrangement is in FIG. 3 shown.
  • the volume increase of the pump chamber 26 must sufficient to evacuate the gas from the vacuum line 12, the interior of the cartridge 4 and the liquid line 14 and to draw the monomer liquid from the liquid container 2 into the interior of the cartridge 4.
  • the expanded pumping space 26 is as in FIG. 3 shown, to greater than the volumes of the lines 12, 14, the interior of the cartridge 4 and the liquid volume of the monomer liquid. It should be remembered that the FIGS. 1 to 3 with respect to the size ratios of the pump chamber 26 and the other volumes are shown only schematically.
  • the mixing tube 8 is pulled out as far as from the interior of the cartridge 4 upwards and can then be stopped at a predetermined breaking point.
  • the sealing piston 10 is rotated against the sterilization piston 9 and thus the gas passage closed by the sealing piston 10.
  • the vacuum line 12 is withdrawn from the sealing piston 10.
  • the cartridge 4 is unscrewed from the foot part 3 and screwed into the internal thread a dispensing tube (not shown), through which the mixed bone cement can be applied.
  • the delivery piston or discharge piston assembled from the sterilization piston 9 and the sealing piston 10 is unlocked and can be driven into the interior of the cartridge 4 with an application device (not shown). As a result, the contents of the cartridge 4, that is, the mixed under negative pressure bone cement from the opposite opening and pressed by the screwed discharge pipe.
  • the components of the vacuum mixing system can be made of a plastic except for the glass ampoule 40 and the steel spring 28 and the output components of the bone cement by injection molding.
  • the lines 12, 14 may be made of a different plastic.
  • the vacuum line 12 must be flexible in order to be able to arrange the sealing piston 10 movably on the mixing tube 8.
  • the lines 12, 14 and the pump 18 are arranged up to the head of the screw 30 in a plastic housing, which has a flat bottom, so that the vacuum mixing system can be placed on a flat surface.
  • the two starting components of the bone cement can be stored and mixed at any later time under vacuum. It has to do that Vacuum mixing system to be connected to any external supply (electricity, water or compressed gas).
  • the energy required to generate the negative pressure is stored in the tensioned steel spring 28 as energy storage.
  • a tensioned tension spring could be used, which is stretched between the opening 36 and the piston 22 in the interior of the hollow cylinder 20 to train, or it could be a tensioned gas spring are used.
  • the construction with a steel spring 28, in particular with a compression spring 28 is simpler and less expensive.
  • FIG. 4 shows a schematic cross-sectional view of another vacuum mixing system according to the invention with a simplified structure.
  • the vacuum mixing system comprises a cartridge system 51 which is screwed onto a base 53.
  • the cartridge system 51 includes a cartridge 54 having a cylindrical interior.
  • the interior of the cartridge 54 is at the front (in FIG. 4 below), wherein the front discharge opening has an internal thread and the cartridge 54 is screwed with the internal thread on an external thread on the base 53.
  • mixing vanes 56 of a mixing device 56 are arranged on a mixing tube 58 which is movable in the interior of the cartridge 54 in the longitudinal direction and can be rotated axially.
  • the mixing tube 58 is guided by a two-part discharge piston 59, 60, which consists of a sterilization piston 59 and a sealing piston 60.
  • the function of the two Austragskolbenmaschine 59, 60 corresponds to the function of Austragskolbenforce 9, 10 according to the first embodiment.
  • the mixing tube 58 terminates at a handle 61 with which the mixing device 56 from outside the cartridge 54 is operable.
  • this version does not have a fluid line which is located in the connection area (in FIG. 4 below) would have to open into the cartridge 54.
  • All components of the bone cement are simply attached to the back of the cartridge 54 (in FIG. 4 top) filled in the interior of the cartridge 54.
  • the two piston parts 59, 60 are first released from the cartridge 54.
  • the sterilizing piston 59 is first inserted, the contents briefly sterilized (for this purpose, the sterilizing piston 59 is permeable to ethylene dioxide) and then the sealing piston 60 with a flexible connected thereto Connecting line 62 and vacuum line 62 used in the sterilization piston 59 and connected thereto via a detent.
  • the sealing piston 60 By inserting the sealing piston 60, the interior of the cartridge 54 is sealed to the outside gas-tight and pressure-tight up to the connection for the vacuum line 62 to the outside.
  • the vacuum line 62 is connected to a pump 68 which is open on one side at the base surfaces in some areas (in FIG. 4 Open below) hollow cylinder 70 is constructed, which is perpendicular to the base 53.
  • the pump 68 also has a piston 72, which in an unlocked state (in FIG. 4 not shown) in the hollow cylinder 70 is axially movable and divides the interior of the hollow cylinder 70 in two gas-tight and pressure-tight parts.
  • the vacuum line 62 opens into a pump chamber 76, which is closed to the outside gas and pressure-tight.
  • a tensioned compression spring 78 is arranged in the pump chamber 76, which presses the piston 72 in the direction of the base 53 facing the base surface of the hollow cylinder 70.
  • the reason why the piston 72 does not move in the locked state due to the compression spring 78 is because the piston 72 is secured with a screw 80 manually operable from the outside.
  • the screw 80 has for this purpose an external thread 82, which engages in an internal thread 83 in an axial tube piece of the piston 72 and thereby holds this in position.
  • the screw 80 is gas- and pressure-tight and rotatably guided by the upper top surface of the hollow cylinder 70. By turning the screw 80 it can be released from the piston 72 and the pump 68 is triggered.
  • the screw 80 thus serves as a manual control element for retrieving the energy from the compression spring 78, which serves as an energy store.
  • the pressure spring 78 accelerates the unlocked or released piston 72 in the direction of the pedestal 53. While the air escapes from the part of the interior of the hollow cylinder 70 facing the pedestal 53 through an opening 86, the pressure in the expanding pump chamber 76 decreases. As a result, gases are evacuated from the vacuum line 62 and through the vacuum line 62 from the interior of the cartridge 54.
  • the piston 72 is pressed by the compression spring 78 as far as the stop on the base 53 facing the base surface of the hollow cylinder 70.
  • an extension 84 on the base 53 pressed side of the piston 72 through the opening 86 and tilts there a rocker arm 87. By the movement and the position of the rocker arm 87 can be seen from the outside that and whether the pump 68 has completed the pumping operation.
  • the increase in volume of the pumping space 76 by the pumping operation is sufficient to generate a sufficient vacuum in the interior of the cartridge 54.
  • a vacuum may already be sufficient if the pressure in the interior of the cartridge 54 is reduced by at least 50%, but is preferably reduced by at least 90%.
  • the starting components filled therein can be mixed with the mixing device 56 by moving the mixing tube 58 with the handle 61.
  • the sealing piston 60 is rotated against the sterilizing piston 59 and thus the gas passage closed by the sealing piston 60.
  • the vacuum line 62 is withdrawn or removed from the sealing piston 60.
  • the cartridge 54 is unscrewed from the base 53 and screwed into the internal thread, a dispensing tube (not shown), through which the mixed bone cement from the cartridge 54 can be applied.
  • the dispensing piston 59, 60 assembled from the sterilizing piston 59 and the sealing piston 60 is unlatched and can be driven into the interior of the cartridge 54 with an application device, that is, with a conventional dispensing device (not shown).
  • an application device that is, with a conventional dispensing device (not shown).
  • the components of the vacuum mixing system can be manufactured by injection molding of a plastic except for the starting components of the bone cement. Preferably, however, there is also the compression spring 78 made of steel.
  • the vacuum line 62 may be made of a different plastic. The vacuum line 62 must be flexible in order to be able to arrange the sealing piston 60 movably on the mixing tube 58.
  • the vacuum mixing system does not need to be connected to any external supply (electricity, water or compressed gas) to be fully functional. As a result, the vacuum mixing system interferes less than conventional vacuum mixing systems and can also be used mobile at any time.
  • the for generating the negative pressure or Vacuum necessary energy is stored in the tensioned compression spring 78 as energy storage, which can easily be triggered by operating the screw 80.
  • a tensioned tension spring or a tensioned gas spring could also be used.
  • the structure with a compression spring 78 made of steel is simpler and less expensive and therefore preferred.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Accessories For Mixers (AREA)

Claims (19)

  1. Système de mélange sous vide pour le mélange de ciment osseux de polyméthylméthacrylate présentant
    au moins une cartouche (4, 54) avec un espace interne pouvant être évacué pour le mélange du ciment osseux,
    une pompe (18, 68) pour la génération d'une dépression et
    une conduite de connexion (12, 62) qui connecte l'espace interne de l'au moins une cartouche (4, 54) à la pompe (18, 68) pour la génération d'une dépression,
    caractérisé en ce que
    le système de mélange sous vide présente un élément de rappel tendu (28, 78) pour l'entraînement de la pompe (18, 68) qui est connecté ou peut être connecté à la pompe (18, 68) et dans lequel de l'énergie est emmagasinée pour au moins un processus de pompage de la pompe (18, 68), dans lequel une dépression peut être générée lors du processus de pompage par une consommation d'énergie provenant de l'élément de rappel tendu (28, 78) avec la pompe (18, 68) de sorte que du gaz provenant de l'espace interne de l'au moins une cartouche (4, 54) peut être évacué avec la dépression à travers la conduite de connexion (12, 62).
  2. Système de mélange sous vide selon la revendication 1, caractérisé en ce que la pompe (18, 68) présente un espace de pompage étanche au gaz (26, 76) et un piston mobile (22, 72) ou une paroi mobile est prévu(e) dans la pompe (18, 68) comme délimitation de l'espace de pompage (26, 76), dans lequel le piston (22, 72) ou la paroi peut être entraîné(e) avec l'énergie de l'élément de rappel tendu (28, 78) dans une direction, de préférence unidirectionnelle, de sorte que l'espace de pompage (26, 76) est agrandi par le déplacement du piston (22, 72) ou de la paroi et l'espace interne de l'au moins une cartouche (4, 54) peut être évacué à travers la conduite de connexion (12, 62) avec la dépression se produisant de ce fait dans l'espace de pompage (26, 76).
  3. Système de mélange sous vide selon la revendication 2, caractérisé en ce que l'agrandissement de volume de l'espace de pompage (26, 76) est au moins aussi grand que le volume libre de l'espace interne de la cartouche (4, 54), de préférence l'agrandissement de volume de l'espace de pompage (26, 76) est au moins aussi grand que la somme du volume de l'espace interne de la cartouche (4, 54) dans lequel un premier composant pulvérulent du ciment osseux de PMMA est contenu et du volume de la conduite de connexion (12, 62) et du volume d'une conduite (14) entre l'espace interne et un récipient de fluide (2) et du volume d'un fluide à mélanger avec le premier composant du ciment osseux de PMMA dans la cartouche (4, 54) dans le récipient de fluide (2), dans lequel le fluide est un second composant du ciment osseux de PMMA.
  4. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    le système de mélange sous vide présente un dispositif de mélange (6, 56) pour le mélange du contenu de l'au moins une cartouche (4, 54), dans lequel le dispositif de mélange (6, 56) est de préférence disposé dans l'espace interne de la cartouche (4, 54) et peut être entraîné manuellement ou par un moteur.
  5. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    le système de mélange sous vide a moins de 30 kg de poids total, a de manière particulièrement préférée moins de 10 kg de poids total.
  6. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    le système de mélange sous vide présente un élément de commande (30, 80) pouvant être commandé manuellement par la commande duquel l'énergie provenant de l'élément de rappel tendu (28, 78) peut être libérée, dans lequel la pompe (18, 68) est à entraîner par l'énergie libérée et la pompe entraînée (18, 68) évacue l'espace interne de la cartouche (4, 54).
  7. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    l'élément de rappel tendu (28, 78) est un ressort tendu (28, 78), de manière particulièrement préférée un ressort d'acier tendu (28).
  8. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    un piston d'extraction mobile (9, 10, 59, 60) pour l'extraction du ciment osseux mélangé de la cartouche (4, 54) est disposé dans l'espace interne de la cartouche (4, 54), dans lequel le piston d'extraction (9, 10, 59, 60) est de préférence bloqué ou peut être bloqué de manière à pouvoir être détaché pour empêcher un déplacement du piston d'extraction (9, 10, 59, 60) sous l'effet de la dépression.
  9. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    la pompe (18, 68) est à entraîner par l'élément de rappel tendu (28, 78), notamment par un élément de ressort tendu (28, 78), dans lequel une expansion ou une contraction de l'élément de rappel (28, 78), notamment de l'élément de ressort (28, 78), génère de préférence une dépression dans l'espace interne de la cartouche (4, 54) par rapport à l'atmosphère environnante.
  10. Système de mélange sous vide selon une des revendications précédentes,
    caractérisé en ce que
    la cartouche (4, 54) est une cartouche de ciment (4, 54) remplie de poudre de ciment et le système de mélange sous vide présente un récipient (2) séparé de la cartouche de ciment (4, 54) dans lequel un fluide monomère est contenu, dans lequel le récipient (2) est connecté à l'espace interne de la cartouche de ciment (4, 54) de manière imperméable au fluide à travers un élément de séparation à ouvrir (44) et l'espace interne de la cartouche de ciment (4, 54) est connecté ou peut être connecté à la pompe (18, 68) de manière perméable au gaz.
  11. Système de mélange sous vide selon une des revendications précédentes, caractérisé en ce que
    la pompe (18, 68) est construite avec
    un cylindre creux (20, 70), dans lequel le cylindre creux (20, 70) est connecté ou peut être connecté à l'espace interne de la cartouche (4, 54),
    une fermeture étanche au gaz à une extrémité du cylindre creux,
    un piston (22, 72) qui est disposé de manière mobile axialement, de manière étanche au gaz dans le cylindre creux (20, 70),
    au moins un élément de ressort (28, 78) comme élément de rappel tendu (28, 78) qui est disposé entre le piston (22, 72) et la fermeture,
    un élément de connexion (30, 80) qui est connecté au piston (22, 72) de manière à pouvoir être détaché, qui maintient le piston (22, 72) de manière fixe en position dans le cylindre creux (20, 70) et maintient l'élément de ressort (28, 78) tendu ou comprimé, dans lequel l'élément de connexion (30, 80) est guidé hors du cylindre creux (20, 70) à travers un passage étanche au gaz et peut être détaché du piston (22, 72) de l'extérieur,
    dans lequel après détachement de la connexion de l'élément de connexion (30, 80) par expansion de l'élément de ressort (28, 78), le piston (22, 72) peut être déplacé axialement à l'opposé de la fermeture.
  12. Système de mélange sous vide selon la revendication 11, caractérisé en ce que
    l'élément de ressort (28, 78) est comprimé à l'état de stockage et est maintenu dans l'état comprimé avec le piston (22, 72) de la pompe (18, 68) par l'élément de connexion bloqué (30, 80).
  13. Système de mélange sous vide selon la revendication 11 ou 12, caractérisé en ce que
    après l'expansion de l'élément de ressort (28, 78) au sein du cylindre creux (20, 70), le piston (22, 72) est poussé de sorte que le volume de l'espace de pompage (26, 76) formé par le cylindre creux (20, 70), la fermeture et le piston (22, 72) est au moins identique au volume de l'espace interne de la cartouche (4, 54) à évacuer.
  14. Système de mélange sous vide selon une des revendications 11 à 13,
    caractérisé en ce que
    un élément de délimitation est disposé à l'extrémité du cylindre creux (20, 70), que le déplacement du piston (22, 72) est limité de telle sorte que celui-ci ne peut pas sortir du cylindre creux (20, 70).
  15. Système de mélange sous vide selon une des revendications 11 à 14,
    caractérisé en ce que
    le piston (22, 72) contient un marqueur optique (34, 87) sur le côté détourné de la fermeture qui est reconnaissable visuellement sur le côté externe du système de mélange sous vide lors du déplacement maximal effectué du piston (22, 72) et indique de ce fait la position du piston (22, 72) après son déplacement maximal.
  16. Procédé de mélange de ciment osseux de polyméthylméthacrylate dans un espace interne d'une cartouche (4, 54) d'un système de mélange sous vide, notamment d'un système de mélange sous vide selon une des revendications précédentes, dans lequel
    une énergie emmagasinée dans un réservoir d'énergie (28, 78) intégré dans le système de mélange sous vide est utilisée pour l'entraînement d'une pompe (18, 68) du système de mélange sous vide, dans lequel l'espace interne de la cartouche (4, 54) est évacué avec la pompe (18, 68) entraînée de cette manière et un ciment osseux est mélangé dans l'espace interne de la cartouche (4, 54),
    caractérisé en ce que
    le volume d'un espace de pompage (26, 76) de la pompe (18, 68) est agrandi par détente d'un élément de rappel (28, 78) comme réservoir d'énergie intégré (28, 78) et l'espace interne de la cartouche (4, 54) est évacué par la dépression se produisant de ce fait.
  17. Procédé selon la revendication 16, caractérisé en ce que une poudre de ciment est contenue dans l'espace interne de la cartouche (4, 54) et un gaz est évacué de l'espace interne de la cartouche (4, 54) avec la pompe (18, 68), un fluide monomère est introduit dans l'espace interne de la cartouche (4, 54) et le fluide monomère est mélangé à la poudre de ciment dans l'espace interne évacué de la cartouche (4, 54).
  18. Procédé selon une des revendications 16 ou 17, caractérisé en ce que la pompe (18, 68) est construite avec
    un cylindre creux (20, 70), dans lequel le cylindre creux (20, 70) est connecté ou peut être connecté à l'espace interne de la cartouche (4, 54),
    une fermeture étanche au gaz à une extrémité du cylindre creux,
    un piston (22, 72) qui est disposé de manière mobile axialement, de manière étanche au gaz dans le cylindre creux (20, 70),
    au moins un élément de ressort (28, 78) comme élément de rappel tendu (28, 78) qui est disposé entre le piston (22, 72) et la fermeture,
    un élément de connexion (30, 80) qui est connecté au piston (22, 72) de manière à pouvoir être détaché, qui maintient le piston (22, 72) de manière fixe en position dans le cylindre creux (20, 70) et maintient l'élément de ressort (28, 78) tendu ou comprimé, dans lequel un élément de connexion (30, 80) est détaché d'un piston (22, 72) de la pompe (18, 68),
    un élément de rappel comprimé (28, 78) déplace ensuite le piston (22, 72) axialement dans un cylindre creux (20, 70) de la pompe (18, 68), moyennant quoi une dépression est générée par rapport à l'atmosphère environnante, du gaz est ce faisant aspiré de l'espace interne de la cartouche (4, 54) dans le cylindre creux (20, 70) à travers une conduite de connexion (12, 62), une poudre de ciment est ensuite mélangée à un fluide monomère manuellement ou de manière motorisée avec un dispositif de mélange (6, 56), la cartouche (4, 54) est ensuite prélevée de la pâte de ciment mélangée et la pâte de ciment est pressée hors de la cartouche (4, 54) par déplacement axial d'un piston d'extraction (9, 10, 59, 60).
  19. Procédé selon la revendication 18, caractérisé en ce que la poudre de ciment est disposée dans la cartouche (4, 54),
    le fluide monomère est disposé dans un récipient (2) séparé de la cartouche (4, 54), dans lequel le fluide monomère est séparé de la poudre de ciment dans la cartouche (4, 54) par le biais d'un élément de séparation (44), l'élément de séparation (44) est ouvert avant que l'élément de connexion (30, 80) ne soit détaché du piston (22, 72) de sorte qu'une connexion perméable au fluide est formée entre l'espace interne de la cartouche (4, 54) et le récipient (2),
    l'élément de ressort comprimé (28, 78) déplace ensuite le piston (22, 72) axialement dans le cylindre creux (20, 70), moyennant quoi une dépression est générée par rapport à l'atmosphère environnante,
    du gaz est ce faisant aspiré de l'espace interne de la cartouche (4, 54) dans le cylindre creux (20, 70) à travers la conduite de connexion (12, 62) et du fluide monomère est aspiré dans la cartouche (4, 54) par la dépression formée dans l'espace interne de la cartouche (4, 54).
EP15170080.4A 2014-06-18 2015-06-01 Système de mélange sous vide et procédé de mélange de ciment osseux en polyméthacrylate de méthyle Active EP2957337B1 (fr)

Applications Claiming Priority (1)

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DE102014108569.8A DE102014108569B3 (de) 2014-06-18 2014-06-18 Vakuummischsystem und Verfahren zum Mischen von Polymethylmethacrylat-Knochenzement

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US (1) US10130926B2 (fr)
EP (1) EP2957337B1 (fr)
JP (1) JP6087985B2 (fr)
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AU (1) AU2015202968B2 (fr)
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DE102015108783B3 (de) 2015-06-03 2016-07-14 Heraeus Medical Gmbh Vorrichtung zum Mischen und Lagern von Polymethylmethacrylat-Knochenzement
DE102015111320B4 (de) * 2015-07-13 2018-10-18 Heraeus Medical Gmbh Vakuummischsystem und Verfahren zum Mischen von Polymethylmethacrylat-Knochenzement
DE102015116797B4 (de) 2015-10-02 2018-08-23 Heraeus Medical Gmbh Vorrichtung und Verfahren zum Lagern und Mischen eines Knochenzements
DE102015121274B3 (de) 2015-12-07 2017-04-06 Heraeus Medical Gmbh Vakuummischvorrichtung mit Bedienelement und Pumpe zum Mischen von Polymethylmethacrylat-Knochenzement
DE102015121277B3 (de) * 2015-12-07 2017-04-06 Heraeus Medical Gmbh Vakuummischvorrichtung mit Bedienelement, Druck- und Vakuumpumpe zum Mischen von Polymethylmethacrylat-Knochenzement
DE102015121276B3 (de) * 2015-12-07 2017-04-06 Heraeus Medical Gmbh Mischvorrichtung mit Bedienelement und Druckpumpe zum Mischen von Polymethylmethacrylat-Knochenzement
DE102016106261B4 (de) * 2016-04-06 2018-03-15 Heraeus Medical Gmbh Vorrichtung zum Mischen und Lagern von Polymethylmethacrylat-Knochenzement mit Druckpumpe und Ampullenbrecher
DE102016110561A1 (de) * 2016-06-08 2017-12-14 Heraeus Medical Gmbh Lager- und Mischvorrichtung zur Herstellung eines Knochenzements
DE102016110564B4 (de) * 2016-06-08 2018-05-09 Heraeus Medical Gmbh Lager- und Mischvorrichtung für Knochenzement mit Druckpumpe
CN112168324B (zh) * 2019-07-04 2022-09-06 北京中科盛康科技有限公司 一种骨水泥搅拌器
EP3815777B1 (fr) * 2019-10-30 2023-08-02 medmix Switzerland AG Système de mélange et de distribution et procédé de mélange et de distribution de matériau à partir d'un système de mélange et de distribution
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CA2893275C (fr) 2017-07-04
JP2016026545A (ja) 2016-02-18
DE102014108569B3 (de) 2015-10-22
US20150367301A1 (en) 2015-12-24
EP2957337A1 (fr) 2015-12-23
CN105170004A (zh) 2015-12-23
AU2015202968A1 (en) 2016-01-21
US10130926B2 (en) 2018-11-20
CA2893275A1 (fr) 2015-12-18
JP6087985B2 (ja) 2017-03-01
CN105170004B (zh) 2018-03-16
AU2015202968B2 (en) 2016-08-11

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