EP2952196A4 - Comprimé multicouche contenant du telmisartan et de l'hydrochlorothiazide - Google Patents

Comprimé multicouche contenant du telmisartan et de l'hydrochlorothiazide

Info

Publication number
EP2952196A4
EP2952196A4 EP14745455.7A EP14745455A EP2952196A4 EP 2952196 A4 EP2952196 A4 EP 2952196A4 EP 14745455 A EP14745455 A EP 14745455A EP 2952196 A4 EP2952196 A4 EP 2952196A4
Authority
EP
European Patent Office
Prior art keywords
hydrochlorothiazide
tablet containing
multilayer tablet
containing telmisartan
telmisartan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14745455.7A
Other languages
German (de)
English (en)
Other versions
EP2952196A1 (fr
Inventor
Wataru IZUI
Yoshiyuki Ogawa
Mami KATSUMOTO
Masaya Hizaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sawai Pharmaceutical Co Ltd
Original Assignee
Sawai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sawai Pharmaceutical Co Ltd filed Critical Sawai Pharmaceutical Co Ltd
Publication of EP2952196A1 publication Critical patent/EP2952196A1/fr
Publication of EP2952196A4 publication Critical patent/EP2952196A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP14745455.7A 2013-01-31 2014-01-31 Comprimé multicouche contenant du telmisartan et de l'hydrochlorothiazide Withdrawn EP2952196A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013016652 2013-01-31
PCT/JP2014/052361 WO2014119767A1 (fr) 2013-01-31 2014-01-31 Comprimé multicouche contenant du telmisartan et de l'hydrochlorothiazide

Publications (2)

Publication Number Publication Date
EP2952196A1 EP2952196A1 (fr) 2015-12-09
EP2952196A4 true EP2952196A4 (fr) 2016-08-03

Family

ID=51262464

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14745455.7A Withdrawn EP2952196A4 (fr) 2013-01-31 2014-01-31 Comprimé multicouche contenant du telmisartan et de l'hydrochlorothiazide

Country Status (4)

Country Link
US (1) US20150335579A1 (fr)
EP (1) EP2952196A4 (fr)
JP (1) JP6379044B2 (fr)
WO (1) WO2014119767A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6948357B2 (ja) * 2019-03-19 2021-10-13 株式会社Moresco 熱可塑性組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063737A1 (fr) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Therapie combinatoire impliquant le telmisartan et l'hydrochlorothiazide

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1149084C (zh) * 1997-12-26 2004-05-12 大日本制药株式会社 治疗神经变性病药物
PT1854454E (pt) 2002-01-16 2014-01-09 Boehringer Ingelheim Pharma Método para a preparação de telmisartan amorfo
DE10244681A1 (de) * 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung
JP4834553B2 (ja) * 2004-09-17 2011-12-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 医薬組成物
KR101047042B1 (ko) * 2004-11-23 2011-07-06 동화약품주식회사 생체이용율을 향상시킨 경구용 제제
JP2009515956A (ja) * 2005-11-22 2009-04-16 テバ ファーマシューティカル インダストリーズ リミティド テルミサルタンの医薬組成物
US8637078B2 (en) 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
KR100762847B1 (ko) * 2006-01-27 2007-10-04 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
CN101652139A (zh) * 2007-03-29 2010-02-17 第一三共株式会社 药物组合物
CA2644179C (fr) * 2007-11-21 2018-09-25 Pharmascience Inc. Composition pharmaceutique inedite comprenant une matrice de desintegration
KR101057640B1 (ko) * 2009-05-27 2011-08-18 (주)다산메디켐 발포성 층을 포함하는 다층 정제
TWI629059B (zh) * 2010-12-28 2018-07-11 興和股份有限公司 Antipyretic and analgesic composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063737A1 (fr) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Therapie combinatoire impliquant le telmisartan et l'hydrochlorothiazide

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"MICARDIS HCT (TELMISARTAN AND HYDROCHLOROTHIAZIDE) TABLETS, 40MG/12.5 MG 80 MG/12.5 MG AND 80 MG/25 MG", INTERNET CITATION, 19 April 2004 (2004-04-19), XP002365096, Retrieved from the Internet <URL:http://www.fda.gov.medwatch/SAFETY/2004/apr_PI/MicardisHCT_PI.pdf> [retrieved on 20060130] *
ROWE R C ET AL: "Handbook of pharmaceutical excipients, 5th Ed", 1 January 2006, HANDBOOK OF PHARMACEUTICAL EXCIPIENTS, PHARMACEUTICAL PRESS [U.A.], LONDON [U.A.], PAGE(S) I-II, ISBN: 978-1-58212-058-4, XP003028137 *
See also references of WO2014119767A1 *

Also Published As

Publication number Publication date
US20150335579A1 (en) 2015-11-26
JP6379044B2 (ja) 2018-08-22
EP2952196A1 (fr) 2015-12-09
WO2014119767A1 (fr) 2014-08-07
JPWO2014119767A1 (ja) 2017-01-26

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20150807

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AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20160630

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 43/00 20060101ALI20160624BHEP

Ipc: A61K 31/549 20060101AFI20160624BHEP

Ipc: A61P 9/12 20060101ALI20160624BHEP

Ipc: A61K 47/02 20060101ALI20160624BHEP

Ipc: A61K 47/04 20060101ALI20160624BHEP

Ipc: A61K 31/4184 20060101ALI20160624BHEP

Ipc: A61P 7/10 20060101ALI20160624BHEP

Ipc: A61K 47/18 20060101ALI20160624BHEP

Ipc: A61K 9/20 20060101ALI20160624BHEP

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18D Application deemed to be withdrawn

Effective date: 20180117